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Shawn M Lyons, Ph.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R00GM124458 (LYONS, SHAWN M) Sep 13, 2018 - Jan 31, 2023
    NIH/NIGMS
    Regulation of Ribosome Biogenesis During Stress
    Role: Principal Investigator
  2. K99GM124458 (LYONS, SHAWN M) Sep 13, 2018 - Aug 31, 2019
    NIH/NIGMS
    Regulation of Ribosome Biogenesis During Stress
    Role: Principal Investigator
  3. F32GM119283 (LYONS, SHAWN M) Apr 1, 2016 - Mar 31, 2018
    NIH/NIGMS
    Characterization of tiRNA-mediated Translational Repression
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Kedersha N, Panas MD, Achorn CA, Lyons S, Tisdale S, Hickman T, Thomas M, Lieberman J, McInerney GM, Ivanov P, Anderson P. Correction: G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2020 01 06; 219(1). PMID: 31851327.
    Citations:    
  2. Gámbaro F, Li Calzi M, Fagúndez P, Costa B, Greif G, Mallick E, Lyons S, Ivanov P, Witwer K, Cayota A, Tosar JP. Stable tRNA halves can be sorted into extracellular vesicles and delivered to recipient cells in a concentration-dependent manner. RNA Biol. 2019 Dec 29; 1-15. PMID: 31885318.
    Citations:    
  3. Aulas A, Lyons SM, Fay MM, Anderson P, Ivanov P. Nitric oxide triggers the assembly of "type II" stress granules linked to decreased cell viability. Cell Death Dis. 2018 11 13; 9(11):1129. PMID: 30425239.
    Citations:    Fields:    
  4. Lyons SM, Fay MM, Ivanov P. The role of RNA modifications in the regulation of tRNA cleavage. FEBS Lett. 2018 09; 592(17):2828-2844. PMID: 30058219.
    Citations:    Fields:    
  5. Lyons SM, Gudanis D, Coyne SM, Gdaniec Z, Ivanov P. Author Correction: Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs. Nat Commun. 2017 12 05; 8(1):2020. PMID: 29209051.
    Citations:    Fields:    
  6. Lyons SM, Gudanis D, Coyne SM, Gdaniec Z, Ivanov P. Identification of functional tetramolecular RNA G-quadruplexes derived from transfer RNAs. Nat Commun. 2017 10 24; 8(1):1127. PMID: 29066746.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  7. Fay MM, Lyons SM, Ivanov P. RNA G-Quadruplexes in Biology: Principles and Molecular Mechanisms. J Mol Biol. 2017 07 07; 429(14):2127-2147. PMID: 28554731.
    Citations: 11     Fields:    Translation:Cells
  8. Lyons SM, Fay MM, Akiyama Y, Anderson PJ, Ivanov P. RNA biology of angiogenin: Current state and perspectives. RNA Biol. 2017 02; 14(2):171-178. PMID: 28010172.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  9. Aulas A, Fay MM, Lyons SM, Achorn CA, Kedersha N, Anderson P, Ivanov P. Stress-specific differences in assembly and composition of stress granules and related foci. J Cell Sci. 2017 03 01; 130(5):927-937. PMID: 28096475.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  10. Lyons SM, Anderson P. RNA-Seeded Functional Amyloids Balance Growth and Survival. Dev Cell. 2016 10 24; 39(2):131-132. PMID: 27780035.
    Citations:    Fields:    
  11. Lyons SM, Cunningham CH, Welch JD, Groh B, Guo AY, Wei B, Whitfield ML, Xiong Y, Marzluff WF. A subset of replication-dependent histone mRNAs are expressed as polyadenylated RNAs in terminally differentiated tissues. Nucleic Acids Res. 2016 Nov 02; 44(19):9190-9205. PMID: 27402160.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  12. Mineo M, Ricklefs F, Rooj AK, Lyons SM, Ivanov P, Ansari KI, Nakano I, Chiocca EA, Godlewski J, Bronisz A. The Long Non-coding RNA HIF1A-AS2 Facilitates the Maintenance of Mesenchymal Glioblastoma Stem-like Cells in Hypoxic Niches. Cell Rep. 2016 06 14; 15(11):2500-9. PMID: 27264189.
    Citations: 19     Fields:    Translation:HumansCells
  13. Lyons SM, Achorn C, Kedersha NL, Anderson PJ, Ivanov P. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016 08 19; 44(14):6949-60. PMID: 27174937.
    Citations: 17     Fields:    Translation:HumansCells
  14. Kedersha N, Panas MD, Achorn CA, Lyons S, Tisdale S, Hickman T, Thomas M, Lieberman J, McInerney GM, Ivanov P, Anderson P. G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits. J Cell Biol. 2016 Mar 28; 212(7):845-60. PMID: 27022092.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  15. Johnson ME, Grassetti AV, Taroni JN, Lyons SM, Schweppe D, Gordon JK, Spiera RF, Lafyatis R, Anderson PJ, Gerber SA, Whitfield ML. Stress granules and RNA processing bodies are novel autoantibody targets in systemic sclerosis. Arthritis Res Ther. 2016 Jan 22; 18:27. PMID: 26801089.
    Citations: 1     Fields:    Translation:HumansCells
  16. Brooks L, Lyons SM, Mahoney JM, Welch JD, Liu Z, Marzluff WF, Whitfield ML. A multiprotein occupancy map of the mRNP on the 3' end of histone mRNAs. RNA. 2015 Nov; 21(11):1943-65. PMID: 26377992.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  17. Terzo EA, Lyons SM, Poulton JS, Temple BR, Marzluff WF, Duronio RJ. Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body. Mol Biol Cell. 2015 Apr 15; 26(8):1559-74. PMID: 25694448.
    Citations: 6     Fields:    Translation:AnimalsCells
  18. Lyons SM, Ricciardi AS, Guo AY, Kambach C, Marzluff WF. The C-terminal extension of Lsm4 interacts directly with the 3' end of the histone mRNP and is required for efficient histone mRNA degradation. RNA. 2014 Jan; 20(1):88-102. PMID: 24255165.
    Citations: 10     Fields:    Translation:HumansCells
  19. Su W, Slepenkov SV, Slevin MK, Lyons SM, Ziemniak M, Kowalska J, Darzynkiewicz E, Jemielity J, Marzluff WF, Rhoads RE. mRNAs containing the histone 3' stem-loop are degraded primarily by decapping mediated by oligouridylation of the 3' end. RNA. 2013 Jan; 19(1):1-16. PMID: 23188809.
    Citations: 19     Fields:    Translation:HumansCells
  20. Martin L, Meier M, Lyons SM, Sit RV, Marzluff WF, Quake SR, Chang HY. Systematic reconstruction of RNA functional motifs with high-throughput microfluidics. Nat Methods. 2012 Dec; 9(12):1192-4. PMID: 23142872.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  21. Yang T, Lyons S, Aguilar C, Cuhel R, Teske A. Microbial communities and chemosynthesis in yellowstone lake sublacustrine hydrothermal vent waters. Front Microbiol. 2011; 2:130. PMID: 21716640.
    Citations: 6     
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.