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Il-Kyu Choi, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gunathilake M, Lee J, Choi IJ, Kim YI, Yoon J, Sul WJ, Kim JF, Kim J. Alterations in Gastric Microbial Communities Are Associated with Risk of Gastric Cancer in a Korean Population: A Case-Control Study. Cancers (Basel). 2020 Sep 14; 12(9). PMID: 32937864.
    Citations:    
  2. Kim J, Lee J, Choi IJ, Kim YI, Sung J, Kim J. TNF genetic polymorphism (rs1799964) may modify the effect of the dietary inflammatory index on gastric cancer in a case-control study. Sci Rep. 2020 09 03; 10(1):14590. PMID: 32883994.
    Citations:    Fields:    
  3. Yim MJ, Lee JM, Kim HS, Choi G, Kim YM, Lee DS, Choi IW. Inhibitory Effects of a Sargassum miyabei Yendo on Cutibacterium acnes-Induced Skin Inflammation. Nutrients. 2020 Aug 27; 12(9). PMID: 32867396.
    Citations:    Fields:    
  4. Yang HJ, Nam SY, Min BH, Ahn JY, Jang JY, Kim J, Kim JH, Lee WS, Lee BE, Joo MK, Park JM, Shin WG, Lee HL, Gweon TG, Park MI, Choi J, Tae CH, Kim YI, Choi IJ. Clinical outcomes of endoscopic resection for undifferentiated intramucosal early gastric cancer larger than 2 cm. Gastric Cancer. 2020 Aug 24. PMID: 32833124.
    Citations:    Fields:    
  5. Yang HJ, Jang JY, Kim SG, Ahn JY, Nam SY, Kim JH, Min BH, Lee WS, Lee BE, Joo MK, Park JM, Shin WG, Lee HL, Gweon TG, Park MI, Choi J, Tae CH, Kim YI, Choi IJ. Risk factors of lymph node metastasis after non-curative endoscopic resection of undifferentiated-type early gastric cancer. Gastric Cancer. 2020 Jul 04. PMID: 32623585.
    Citations:    Fields:    
  6. Kim JH, Lee J, Choi IJ, Kim YI, Kim J. Dietary patterns and gastric cancer risk in a Korean population: a case-control study. Eur J Nutr. 2020 Apr 29. PMID: 32350654.
    Citations:    Fields:    
  7. Gunathilake M, Lee J, Choi IJ, Kim YI, Kim J. Identification of Dietary Pattern Networks Associated with Gastric Cancer Using Gaussian Graphical Models: A Case-Control Study. Cancers (Basel). 2020 Apr 23; 12(4). PMID: 32340406.
    Citations:    
  8. Shin SY, Kim JH, Kook MC, Park DY, Ryu KW, Choi IJ, Noh SH, Kim H, Lee YC. Clinicopathologic Features of Submucosal Papillary Gastric Cancer Differ from Those of Other Differentiated-Type Histologies. Gut Liver. 2020 Apr 17. PMID: 32295332.
    Citations:    Fields:    
  9. Choi IK, Wang Z, Ke Q, Hong M, Qian Y, Zhao X, Liu Y, Kim HJ, Ritz J, Cantor H, Rajewsky K, Wucherpfennig KW, Zhang B. Signaling by the Epstein-Barr virus LMP1 protein induces potent cytotoxic CD4+ and CD8+ T cell responses. Proc Natl Acad Sci U S A. 2018 01 23; 115(4):E686-E695. PMID: 29311309.
    Citations: 3     Fields:    Translation:AnimalsCells
  10. Jung KH, Choi IK, Lee HS, Yan HH, Son MK, Ahn HM, Hong J, Yun CO, Hong SS. Corrigendum to "Oncolytic adenovirus expressing relaxin (YDC002) enhances therapeutic efficacy of gemcitabine against pancreatic cancer" [Cancer Lett. 396 (2017) 155-166]. Cancer Lett. 2017 09 28; 404:93. PMID: 28646638.
    Citations:    Fields:    
  11. Jung KH, Choi IK, Lee HS, Yan HH, Son MK, Ahn HM, Hong J, Yun CO, Hong SS. Oncolytic adenovirus expressing relaxin (YDC002) enhances therapeutic efficacy of gemcitabine against pancreatic cancer. Cancer Lett. 2017 06 28; 396:155-166. PMID: 28315430.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  12. Oh E, Choi IK, Hong J, Yun CO. Oncolytic adenovirus coexpressing interleukin-12 and decorin overcomes Treg-mediated immunosuppression inducing potent antitumor effects in a weakly immunogenic tumor model. Oncotarget. 2017 Jan 17; 8(3):4730-4746. PMID: 28002796.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  13. Wares JR, Crivelli JJ, Yun CO, Choi IK, Gevertz JL, Kim PS. Treatment strategies for combining immunostimulatory oncolytic virus therapeutics with dendritic cell injections. Math Biosci Eng. 2015 Dec; 12(6):1237-56. PMID: 26775859.
    Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
  14. Kim PS, Crivelli JJ, Choi IK, Yun CO, Wares JR. Quantitative impact of immunomodulation versus oncolysis with cytokine-expressing virus therapeutics. Math Biosci Eng. 2015 Aug; 12(4):841-58. PMID: 25974336.
    Citations: 8     Fields:    Translation:AnimalsCells
  15. Jeon YR, Ahn HM, Choi IK, Yun CO, Rah DK, Lew DH, Lee WJ. Hepatocyte growth factor-expressing adenovirus upregulates matrix metalloproteinase-1 expression in keloid fibroblasts. Int J Dermatol. 2016 Mar; 55(3):356-61. PMID: 26234705.
    Citations: 1     Fields:    Translation:HumansCells
  16. Choi IK, Shin H, Oh E, Yoo JY, Hwang JK, Shin K, Yu DC, Yun CO. Potent and long-term antiangiogenic efficacy mediated by FP3-expressing oncolytic adenovirus. Int J Cancer. 2015 Nov 01; 137(9):2253-69. PMID: 25944623.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  17. Lee WJ, Ahn HM, Roh H, Na Y, Choi IK, Lee JH, Kim YO, Lew DH, Yun CO. Decorin-expressing adenovirus decreases collagen synthesis and upregulates MMP expression in keloid fibroblasts and keloid spheroids. Exp Dermatol. 2015 Aug; 24(8):591-7. PMID: 25865370.
    Citations: 7     Fields:    Translation:HumansCells
  18. Ryu J, Kaul Z, Yoon AR, Liu Y, Yaguchi T, Na Y, Ahn HM, Gao R, Choi IK, Yun CO, Kaul SC, Wadhwa R. Identification and functional characterization of nuclear mortalin in human carcinogenesis. J Biol Chem. 2014 Sep 05; 289(36):24832-44. PMID: 25012652.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  19. Choi IK, Strauss R, Richter M, Yun CO, Lieber A. Strategies to increase drug penetration in solid tumors. Front Oncol. 2013; 3:193. PMID: 23898462.
    Citations: 34     
  20. Choi IK, Li Y, Oh E, Kim J, Yun CO. Oncolytic adenovirus expressing IL-23 and p35 elicits IFN-?- and TNF-a-co-producing T cell-mediated antitumor immunity. PLoS One. 2013; 8(7):e67512. PMID: 23844018.
    Citations: 19     Fields:    Translation:AnimalsCells
  21. Lim SA, Kim TJ, Lee JE, Sonn CH, Kim K, Kim J, Choi JG, Choi IK, Yun CO, Kim JH, Yee C, Kumar V, Lee KM. Ex vivo expansion of highly cytotoxic human NK cells by cocultivation with irradiated tumor cells for adoptive immunotherapy. Cancer Res. 2013 Apr 15; 73(8):2598-607. PMID: 23580577.
    Citations: 18     Fields:    Translation:HumansCells
  22. Choi IK, Yun CO. Recent developments in oncolytic adenovirus-based immunotherapeutic agents for use against metastatic cancers. Cancer Gene Ther. 2013 Feb; 20(2):70-6. PMID: 23306610.
    Citations: 21     Fields:    Translation:HumansCells
  23. Lee WJ, Choi IK, Lee JH, Kim YO, Yun CO. A novel three-dimensional model system for keloid study: organotypic multicellular scar model. Wound Repair Regen. 2013 Jan-Feb; 21(1):155-65. PMID: 23231705.
    Citations: 3     Fields:    Translation:HumansCells
  24. Lee WJ, Choi IK, Lee JH, Lee JS, Kim YO, Rah DK, Yun CO. Relaxin-expressing adenovirus decreases collagen synthesis and up-regulates matrix metalloproteinase expression in keloid fibroblasts: in vitro experiments. Plast Reconstr Surg. 2012 Sep; 130(3):407e-17e. PMID: 22929264.
    Citations: 6     Fields:    Translation:HumansCells
  25. Koo T, Choi IK, Kim M, Lee JS, Oh E, Kim J, Yun CO. Negative regulation-resistant p53 variant enhances oncolytic adenoviral gene therapy. Hum Gene Ther. 2012 Jun; 23(6):609-22. PMID: 22248367.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  26. Koom WS, Park SY, Kim W, Kim M, Kim JS, Kim H, Choi IK, Yun CO, Seong J. Combination of radiotherapy and adenovirus-mediated p53 gene therapy for MDM2-overexpressing hepatocellular carcinoma. J Radiat Res. 2012; 53(2):202-10. PMID: 22510592.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  27. Choi KJ, Zhang SN, Choi IK, Kim JS, Yun CO. Strengthening of antitumor immune memory and prevention of thymic atrophy mediated by adenovirus expressing IL-12 and GM-CSF. Gene Ther. 2012 Jul; 19(7):711-23. PMID: 21993173.
    Citations: 16     Fields:    Translation:AnimalsCells
  28. Lee WJ, Yun CO, Yun IS, Kim YO, Choi IK, Yun TJ, Rah DK. Augmentation of rat skin flap viability by relaxin-expressing adenovirus. Wound Repair Regen. 2011 Nov; 19(6):709-17. PMID: 22092841.
    Citations: 2     Fields:    Translation:AnimalsCells
  29. Lee WJ, Kim YO, Choi IK, Rah DK, Yun CO. Adenovirus-relaxin gene therapy for keloids: implication for reversing pathological fibrosis. Br J Dermatol. 2011 Sep; 165(3):673-7. PMID: 21623756.
    Citations: 5     Fields:    Translation:HumansCells
  30. Yoon AR, Gao R, Kaul Z, Choi IK, Ryu J, Noble JR, Kato Y, Saito S, Hirano T, Ishii T, Reddel RR, Yun CO, Kaul SC, Wadhwa R. MicroRNA-296 is enriched in cancer cells and downregulates p21WAF1 mRNA expression via interaction with its 3' untranslated region. Nucleic Acids Res. 2011 Oct; 39(18):8078-91. PMID: 21724611.
    Citations: 19     Fields:    Translation:HumansCells
  31. Zhang SN, Choi IK, Huang JH, Yoo JY, Choi KJ, Yun CO. Optimizing DC vaccination by combination with oncolytic adenovirus coexpressing IL-12 and GM-CSF. Mol Ther. 2011 Aug; 19(8):1558-68. PMID: 21468000.
    Citations: 29     Fields:    Translation:AnimalsCellsPHPublic Health
  32. Choi IK, Lee JS, Zhang SN, Park J, Sonn CH, Lee KM, Yun CO. Oncolytic adenovirus co-expressing IL-12 and IL-18 improves tumor-specific immunity via differentiation of T cells expressing IL-12Rß2 or IL-18Ra. Gene Ther. 2011 Sep; 18(9):898-909. PMID: 21451575.
    Citations: 38     Fields:    Translation:AnimalsCells
  33. Wadhwa R, Ryu J, Gao R, Choi IK, Morrow G, Kaur K, Kim I, Kaul SC, Yun CO, Tanguay RM. Proproliferative functions of Drosophila small mitochondrial heat shock protein 22 in human cells. J Biol Chem. 2010 Feb 05; 285(6):3833-9. PMID: 19948727.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  34. Choi IK, Lee YS, Yoo JY, Yoon AR, Kim H, Kim DS, Seidler DG, Kim JH, Yun CO. Effect of decorin on overcoming the extracellular matrix barrier for oncolytic virotherapy. Gene Ther. 2010 Feb; 17(2):190-201. PMID: 19907500.
    Citations: 25     Fields:    Translation:AnimalsCells
  35. Huang JH, Zhang SN, Choi KJ, Choi IK, Kim JH, Lee MG, Lee M, Kim H, Yun CO. Therapeutic and tumor-specific immunity induced by combination of dendritic cells and oncolytic adenovirus expressing IL-12 and 4-1BBL. Mol Ther. 2010 Feb; 18(2):264-74. PMID: 19738604.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
  36. Lee YS, Kim JH, Choi KJ, Choi IK, Kim H, Cho S, Cho BC, Yun CO. Enhanced antitumor effect of oncolytic adenovirus expressing interleukin-12 and B7-1 in an immunocompetent murine model. Clin Cancer Res. 2006 Oct 01; 12(19):5859-68. PMID: 17020994.
    Citations: 42     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.