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Hisashi Umemori, Ph.D., M.D.

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Mentoring
Available: 07/07/17, Expires: 07/07/21

In the brain, information processing occurs at synapses, and defects in synapse formation underlie many neurological and psychiatric diseases. We are therefore interested in the molecules and mechanisms that regulate synapse formation. The goals of our research are to understand the mechanisms underlying the establishment of appropriate synaptic connections in the mammalian brain and provide clues for the treatment of neurological and psychiatric disorders associated with abnormal synapse formation, such as autism, schizophrenia, and epilepsy. We use molecular & cellular biological, mouse genetics, biochemical, histological, physiological, imaging, and behavioral techniques to understand the principles of functional brain wiring. Students may participate in our studies or can create their own projects.


Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01DA042744 (UMEMORI, HISASHI) Sep 1, 2017 - May 31, 2022
    NIH/NIDA
    Finding the projection-specific dopaminergic synaptic organizers
    Role: Principal Investigator
  2. R01MH111647 (UMEMORI, HISASHI) Aug 16, 2017 - May 31, 2022
    NIH/NIMH
    How do neurons in the brain decide to refine their synaptic connections in vivo?
    Role: Principal Investigator
  3. R01NS092578 (STEVENS, BETH ANN) Mar 15, 2015 - Feb 29, 2020
    NIH/NINDS
    Investigating CD47-SIRPa as novel protective signals during CNS synaptic pruning
    Role: Co-Principal Investigator
  4. R03MH094173 (UMEMORI, HISASHI) Apr 1, 2012 - Mar 31, 2015
    NIH/NIMH
    Small Molecule Inhibitors of FGF22-Mediated Excitatory Synaptogenesis &Epilepsy
    Role: Principal Investigator
  5. R21MH092614 (UMEMORI, HISASHI) Aug 1, 2011 - Jul 31, 2014
    NIH/NIMH
    Synapse Maturation by Activity-Dependent Ectodomain Shedding of SIRP
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Li T, Chiou B, Gilman CK, Luo R, Koshi T, Yu D, Oak HC, Giera S, Johnson-Venkatesh E, Muthukumar AK, Stevens B, Umemori H, Piao X. A splicing isoform of GPR56 mediates microglial synaptic refinement via phosphatidylserine binding. EMBO J. 2020 May 25; e104136. PMID: 32452062.
    Citations:    
  2. Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, Motohashi J, Pai EL, Pelkey KA, Pereira A, Philips T, Sinclair JL, Stogsdill JA, Traunmüller L, Wang J, Wortel J, You W, Abumaria N, Beier KT, Brose N, Burgess HA, Cepko CL, Cloutier JF, Eroglu C, Goebbels S, Kaeser PS, Kay JN, Lu W, Luo L, Mandai K, McBain CJ, Nave KA, Prado MAM, Prado VF, Rothstein J, Rubenstein JLR, Saher G, Sakimura K, Sanes JR, Scheiffele P, Takai Y, Umemori H, Verhage M, Yuzaki M, Zoghbi HY, Kawabe H, Craig AM. Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron. 2020 Apr 08; 106(1):37-65.e5. PMID: 32027825.
    Citations:    
  3. Terauchi A, Durlacher E, Pitino J, Umemori H. Neuronal fibroblast growth factor 22 signaling during development, but not in adults, is involved in anhedonia. Neuroreport. 2020 01 27; 31(2):125-130. PMID: 31895747.
    Citations:    
  4. Lehrman EK, Wilton DK, Litvina EY, Welsh CA, Chang ST, Frouin A, Walker AJ, Heller MD, Umemori H, Chen C, Stevens B. CD47 Protects Synapses from Excess Microglia-Mediated Pruning during Development. Neuron. 2018 10 10; 100(1):120-134.e6. PMID: 30308165.
    Citations:    Fields:    
  5. Nagappan-Chettiar S, Johnson-Venkatesh EM, Umemori H. Tyrosine phosphorylation of the transmembrane protein SIRPa: Sensing synaptic activity and regulating ectodomain cleavage for synapse maturation. J Biol Chem. 2018 08 03; 293(31):12026-12042. PMID: 29914984.
    Citations:    Fields:    
  6. Terauchi A, Gavin E, Wilson J, Umemori H. Selective Inactivation of Fibroblast Growth Factor 22 (FGF22) in CA3 Pyramidal Neurons Impairs Local Synaptogenesis and Affective Behavior Without Affecting Dentate Neurogenesis. Front Synaptic Neurosci. 2017; 9:17. PMID: 29311892.
    Citations:    
  7. Mathew RS, Tatarakis A, Rudenko A, Johnson-Venkatesh EM, Yang YJ, Murphy EA, Todd TP, Schepers ST, Siuti N, Martorell AJ, Falls WA, Hammack SE, Walsh CA, Tsai LH, Umemori H, Bouton ME, Moazed D. A microRNA negative feedback loop downregulates vesicle transport and inhibits fear memory. Elife. 2016 12 21; 5. PMID: 28001126.
    Citations: 1     Fields:    Translation:AnimalsCells
  8. Nagappan-Chettiar S, Johnson-Venkatesh EM, Umemori H. Activity-dependent proteolytic cleavage of cell adhesion molecules regulates excitatory synaptic development and function. Neurosci Res. 2017 Mar; 116:60-69. PMID: 27965136.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Hu HT, Umemori H, Hsueh YP. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Sci Rep. 2016 09 15; 6:33592. PMID: 27627962.
    Citations: 6     Fields:    Translation:AnimalsCells
  10. Terauchi A, Johnson-Venkatesh EM, Bullock B, Lehtinen MK, Umemori H. Retrograde fibroblast growth factor 22 (FGF22) signaling regulates insulin-like growth factor 2 (IGF2) expression for activity-dependent synapse stabilization in the mammalian brain. Elife. 2016 04 15; 5. PMID: 27083047.
    Citations: 4     Fields:    Translation:AnimalsCells
  11. Dabrowski A, Umemori H. Buttressing a balanced brain: Target-derived FGF signaling regulates excitatory/inhibitory tone and adult neurogenesis within the maturating hippocampal network. Neurogenesis (Austin). 2016; 3(1):e1168504. PMID: 27605441.
    Citations: 1     
  12. Williams AJ, Yee P, Smith MC, Murphy GG, Umemori H. Deletion of fibroblast growth factor 22 (FGF22) causes a depression-like phenotype in adult mice. Behav Brain Res. 2016 07 01; 307:11-7. PMID: 27036645.
    Citations: 3     Fields:    Translation:Animals
  13. Johnson-Venkatesh EM, Khan MN, Murphy GG, Sutton MA, Umemori H. Excitability governs neural development in a hippocampal region-specific manner. Development. 2015 Nov 15; 142(22):3879-91. PMID: 26417041.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Dabrowski A, Terauchi A, Strong C, Umemori H. Distinct sets of FGF receptors sculpt excitatory and inhibitory synaptogenesis. Development. 2015 May 15; 142(10):1818-30. PMID: 25926357.
    Citations: 5     Fields:    Translation:AnimalsCells
  15. Jacobi A, Loy K, Schmalz AM, Hellsten M, Umemori H, Kerschensteiner M, Bareyre FM. FGF22 signaling regulates synapse formation during post-injury remodeling of the spinal cord. EMBO J. 2015 May 05; 34(9):1231-43. PMID: 25766255.
    Citations: 4     Fields:    Translation:AnimalsCells
  16. Terauchi A, Timmons KM, Kikuma K, Pechmann Y, Kneussel M, Umemori H. Selective synaptic targeting of the excitatory and inhibitory presynaptic organizers FGF22 and FGF7. J Cell Sci. 2015 Jan 15; 128(2):281-92. PMID: 25431136.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  17. Wang Q, Terauchi A, Yee CH, Umemori H, Traynor JR. 5-HT1A receptor-mediated phosphorylation of extracellular signal-regulated kinases (ERK1/2) is modulated by regulator of G protein signaling protein 19. Cell Signal. 2014 Sep; 26(9):1846-52. PMID: 24793302.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  18. Williams AJ, Umemori H. The best-laid plans go oft awry: synaptogenic growth factor signaling in neuropsychiatric disease. Front Synaptic Neurosci. 2014; 6:4. PMID: 24672476.
    Citations: 7     
  19. Toth AB, Terauchi A, Zhang LY, Johnson-Venkatesh EM, Larsen DJ, Sutton MA, Umemori H. Synapse maturation by activity-dependent ectodomain shedding of SIRPa. Nat Neurosci. 2013 Oct; 16(10):1417-25. PMID: 24036914.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  20. Lee CH, Umemori H. Suppression of epileptogenesis-associated changes in response to seizures in FGF22-deficient mice. Front Cell Neurosci. 2013; 7:43. PMID: 23616746.
    Citations: 10     
  21. Lee CH, Javed D, Althaus AL, Parent JM, Umemori H. Neurogenesis is enhanced and mossy fiber sprouting arises in FGF7-deficient mice during development. Mol Cell Neurosci. 2012 Nov; 51(3-4):61-7. PMID: 22889808.
    Citations: 14     Fields:    Translation:AnimalsCells
  22. Singh R, Su J, Brooks J, Terauchi A, Umemori H, Fox MA. Fibroblast growth factor 22 contributes to the development of retinal nerve terminals in the dorsal lateral geniculate nucleus. Front Mol Neurosci. 2012; 4:61. PMID: 22363257.
    Citations: 14     
  23. Yasuda M, Johnson-Venkatesh EM, Zhang H, Parent JM, Sutton MA, Umemori H. Multiple forms of activity-dependent competition refine hippocampal circuits in vivo. Neuron. 2011 Jun 23; 70(6):1128-42. PMID: 21689599.
    Citations: 24     Fields:    Translation:AnimalsCells
  24. Terauchi A, Umemori H. Specific sets of intrinsic and extrinsic factors drive excitatory and inhibitory circuit formation. Neuroscientist. 2012 Jun; 18(3):271-86. PMID: 21652588.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  25. Dabrowski A, Umemori H. Orchestrating the synaptic network by tyrosine phosphorylation signalling. J Biochem. 2011 Jun; 149(6):641-53. PMID: 21508038.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  26. Delawary M, Tezuka T, Kiyama Y, Yokoyama K, Inoue T, Hattori S, Hashimoto R, Umemori H, Manabe T, Yamamoto T, Nakazawa T. NMDAR2B tyrosine phosphorylation regulates anxiety-like behavior and CRF expression in the amygdala. Mol Brain. 2010 Nov 30; 3:37. PMID: 21118530.
    Citations: 8     Fields:    Translation:AnimalsCells
  27. Johnson-Venkatesh EM, Umemori H. Secreted factors as synaptic organizers. Eur J Neurosci. 2010 Jul; 32(2):181-90. PMID: 20646052.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  28. Terauchi A, Johnson-Venkatesh EM, Toth AB, Javed D, Sutton MA, Umemori H. Distinct FGFs promote differentiation of excitatory and inhibitory synapses. Nature. 2010 Jun 10; 465(7299):783-7. PMID: 20505669.
    Citations: 73     Fields:    Translation:AnimalsCells
  29. Taniguchi S, Nakazawa T, Tanimura A, Kiyama Y, Tezuka T, Watabe AM, Katayama N, Yokoyama K, Inoue T, Izumi-Nakaseko H, Kakuta S, Sudo K, Iwakura Y, Umemori H, Inoue T, Murphy NP, Hashimoto K, Kano M, Manabe T, Yamamoto T. Involvement of NMDAR2A tyrosine phosphorylation in depression-related behaviour. EMBO J. 2009 Dec 02; 28(23):3717-29. PMID: 19834457.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  30. Umemori H. Weaving the neuronal net with target-derived fibroblast growth factors. Dev Growth Differ. 2009 Apr; 51(3):263-70. PMID: 19210540.
    Citations: 13     Fields:    Translation:HumansAnimals
  31. Umemori H, Sanes JR. Signal regulatory proteins (SIRPS) are secreted presynaptic organizing molecules. J Biol Chem. 2008 Dec 05; 283(49):34053-61. PMID: 18819922.
    Citations: 22     Fields:    Translation:AnimalsCells
  32. Nakazawa T, Kuriu T, Tezuka T, Umemori H, Okabe S, Yamamoto T. Regulation of dendritic spine morphology by an NMDA receptor-associated Rho GTPase-activating protein, p250GAP. J Neurochem. 2008 May; 105(4):1384-93. PMID: 18331582.
    Citations: 24     Fields:    Translation:AnimalsCells
  33. Fox MA, Sanes JR, Borza DB, Eswarakumar VP, Fässler R, Hudson BG, John SW, Ninomiya Y, Pedchenko V, Pfaff SL, Rheault MN, Sado Y, Segal Y, Werle MJ, Umemori H. Distinct target-derived signals organize formation, maturation, and maintenance of motor nerve terminals. Cell. 2007 Apr 06; 129(1):179-93. PMID: 17418794.
    Citations: 92     Fields:    Translation:HumansAnimalsCells
  34. Nakazawa T, Komai S, Watabe AM, Kiyama Y, Fukaya M, Arima-Yoshida F, Horai R, Sudo K, Ebine K, Delawary M, Goto J, Umemori H, Tezuka T, Iwakura Y, Watanabe M, Yamamoto T, Manabe T. NR2B tyrosine phosphorylation modulates fear learning as well as amygdaloid synaptic plasticity. EMBO J. 2006 Jun 21; 25(12):2867-77. PMID: 16710293.
    Citations: 48     Fields:    Translation:AnimalsCells
  35. Fox MA, Umemori H. Seeking long-term relationship: axon and target communicate to organize synaptic differentiation. J Neurochem. 2006 Jun; 97(5):1215-31. PMID: 16638017.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
  36. Zhang X, Ibrahimi OA, Olsen SK, Umemori H, Mohammadi M, Ornitz DM. Receptor specificity of the fibroblast growth factor family. The complete mammalian FGF family. J Biol Chem. 2006 Jun 09; 281(23):15694-700. PMID: 16597617.
    Citations: 335     Fields:    Translation:HumansCells
  37. Umemori H, Linhoff MW, Ornitz DM, Sanes JR. FGF22 and its close relatives are presynaptic organizing molecules in the mammalian brain. Cell. 2004 Jul 23; 118(2):257-70. PMID: 15260994.
    Citations: 92     Fields:    Translation:AnimalsCells
  38. Yoshida Y, Nakamura T, Komoda M, Satoh H, Suzuki T, Tsuzuku JK, Miyasaka T, Yoshida EH, Umemori H, Kunisaki RK, Tani K, Ishii S, Mori S, Suganuma M, Noda T, Yamamoto T. Mice lacking a transcriptional corepressor Tob are predisposed to cancer. Genes Dev. 2003 May 15; 17(10):1201-6. PMID: 12756225.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  39. Yoshida Y, von Bubnoff A, Ikematsu N, Blitz IL, Tsuzuku JK, Yoshida EH, Umemori H, Miyazono K, Yamamoto T, Cho KW. Tob proteins enhance inhibitory Smad-receptor interactions to repress BMP signaling. Mech Dev. 2003 May; 120(5):629-37. PMID: 12782279.
    Citations: 18     Fields:    Translation:AnimalsCells
  40. Nakazawa T, Watabe AM, Tezuka T, Yoshida Y, Yokoyama K, Umemori H, Inoue A, Okabe S, Manabe T, Yamamoto T. p250GAP, a novel brain-enriched GTPase-activating protein for Rho family GTPases, is involved in the N-methyl-d-aspartate receptor signaling. Mol Biol Cell. 2003 Jul; 14(7):2921-34. PMID: 12857875.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  41. Kohda K, Kamiya Y, Matsuda S, Kato K, Umemori H, Yuzaki M. Heteromer formation of delta2 glutamate receptors with AMPA or kainate receptors. Brain Res Mol Brain Res. 2003 Jan 31; 110(1):27-37. PMID: 12573530.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  42. Umemori H, Ogura H, Tozawa N, Mikoshiba K, Nishizumi H, Yamamoto T. Impairment of N-methyl-D-aspartate receptor-controlled motor activity in LYN-deficient mice. Neuroscience. 2003; 118(3):709-13. PMID: 12710978.
    Citations: 8     Fields:    Translation:AnimalsCells
  43. Nakazawa T, Komai S, Tezuka T, Hisatsune C, Umemori H, Semba K, Mishina M, Manabe T, Yamamoto T. Characterization of Fyn-mediated tyrosine phosphorylation sites on GluR epsilon 2 (NR2B) subunit of the N-methyl-D-aspartate receptor. J Biol Chem. 2001 Jan 05; 276(1):693-9. PMID: 11024032.
    Citations: 130     Fields:    Translation:HumansAnimalsCells
  44. Yoshida Y, Tanaka S, Umemori H, Minowa O, Usui M, Ikematsu N, Hosoda E, Imamura T, Kuno J, Yamashita T, Miyazono K, Noda M, Noda T, Yamamoto T. Negative regulation of BMP/Smad signaling by Tob in osteoblasts. Cell. 2000 Dec 22; 103(7):1085-97. PMID: 11163184.
    Citations: 81     Fields:    Translation:AnimalsCells
  45. Hironaka K, Umemori H, Tezuka T, Mishina M, Yamamoto T. The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits. J Biol Chem. 2000 May 26; 275(21):16167-73. PMID: 10748123.
    Citations: 14     Fields:    Translation:AnimalsCells
  46. Umemori H, Hayashi T, Inoue T, Nakanishi S, Mikoshiba K, Yamamoto T. Involvement of protein tyrosine phosphatases in activation of the trimeric G protein Gq/11. Oncogene. 1999 Dec 02; 18(51):7399-402. PMID: 10602498.
    Citations: 3     Fields:    Translation:AnimalsCells
  47. Hisatsune C, Umemori H, Mishina M, Yamamoto T. Phosphorylation-dependent interaction of the N-methyl-D-aspartate receptor epsilon 2 subunit with phosphatidylinositol 3-kinase. Genes Cells. 1999 Nov; 4(11):657-66. PMID: 10620012.
    Citations: 19     Fields:    Translation:AnimalsCells
  48. Horikawa K, Nishizumi H, Umemori H, Aizawa S, Takatsu K, Yamamoto T. Distinctive roles of Fyn and Lyn in IgD- and IgM-mediated signaling. Int Immunol. 1999 Sep; 11(9):1441-9. PMID: 10464165.
    Citations: 8     Fields:    Translation:AnimalsCells
  49. Umemori H, Kadowaki Y, Hirosawa K, Yoshida Y, Hironaka K, Okano H, Yamamoto T. Stimulation of myelin basic protein gene transcription by Fyn tyrosine kinase for myelination. J Neurosci. 1999 Feb 15; 19(4):1393-7. PMID: 9952416.
    Citations: 27     Fields:    Translation:AnimalsCells
  50. Tezuka T, Umemori H, Akiyama T, Nakanishi S, Yamamoto T. PSD-95 promotes Fyn-mediated tyrosine phosphorylation of the N-methyl-D-aspartate receptor subunit NR2A. Proc Natl Acad Sci U S A. 1999 Jan 19; 96(2):435-40. PMID: 9892651.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  51. Hayashi T, Umemori H, Mishina M, Yamamoto T. The AMPA receptor interacts with and signals through the protein tyrosine kinase Lyn. Nature. 1999 Jan 07; 397(6714):72-6. PMID: 9892356.
    Citations: 46     Fields:    Translation:AnimalsCells
  52. Miyatake S, Nakaseko C, Umemori H, Yamamoto T, Saito T. Src family tyrosine kinases associate with and phosphorylate CTLA-4 (CD152). Biochem Biophys Res Commun. 1998 Aug 19; 249(2):444-8. PMID: 9712716.
    Citations: 13     Fields:    Translation:AnimalsCells
  53. Yoshida Y, Matsuda S, Ikematsu N, Kawamura-Tsuzuku J, Inazawa J, Umemori H, Yamamoto T. ANA, a novel member of Tob/BTG1 family, is expressed in the ventricular zone of the developing central nervous system. Oncogene. 1998 May; 16(20):2687-93. PMID: 9632145.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  54. Hisatsune C, Umemori H, Inoue T, Michikawa T, Kohda K, Mikoshiba K, Yamamoto T. Phosphorylation-dependent regulation of N-methyl-D-aspartate receptors by calmodulin. J Biol Chem. 1997 Aug 15; 272(33):20805-10. PMID: 9252405.
    Citations: 22     Fields:    Translation:HumansCells
  55. Umemori H, Inoue T, Kume S, Sekiyama N, Nagao M, Itoh H, Nakanishi S, Mikoshiba K, Yamamoto T. Activation of the G protein Gq/11 through tyrosine phosphorylation of the alpha subunit. Science. 1997 Jun 20; 276(5320):1878-81. PMID: 9188537.
    Citations: 20     Fields:    Translation:AnimalsCells
  56. Fusaki N, Matsuda S, Nishizumi H, Umemori H, Yamamoto T. Physical and functional interactions of protein tyrosine kinases, p59fyn and ZAP-70, in T cell signaling. J Immunol. 1996 Feb 15; 156(4):1369-77. PMID: 8568236.
    Citations: 7     Fields:    Translation:AnimalsCells
  57. Tezuka T, Umemori H, Fusaki N, Yagi T, Takata M, Kurosaki T, Yamamoto T. Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling. J Exp Med. 1996 Feb 01; 183(2):675-80. PMID: 8627181.
    Citations: 24     Fields:    Translation:Cells
  58. Umemori H, Sato S, Yagi T, Aizawa S, Yamamoto T. Initial events of myelination involve Fyn tyrosine kinase signalling. Nature. 1994 Feb 10; 367(6463):572-6. PMID: 7509042.
    Citations: 86     Fields:    Translation:AnimalsCells
  59. Yamanashi Y, Okada M, Semba T, Yamori T, Umemori H, Tsunasawa S, Toyoshima K, Kitamura D, Watanabe T, Yamamoto T. Identification of HS1 protein as a major substrate of protein-tyrosine kinase(s) upon B-cell antigen receptor-mediated signaling. Proc Natl Acad Sci U S A. 1993 Apr 15; 90(8):3631-5. PMID: 7682714.
    Citations: 42     Fields:    Translation:HumansCells
  60. Umemori H, Wanaka A, Kato H, Takeuchi M, Tohyama M, Yamamoto T. Specific expressions of Fyn and Lyn, lymphocyte antigen receptor-associated tyrosine kinases, in the central nervous system. Brain Res Mol Brain Res. 1992 Dec; 16(3-4):303-10. PMID: 1337939.
    Citations: 28     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.