Harvard Catalyst Profiles

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Charilaos Filippakis, Ph.D.

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Biography
2007 - 2012
Scholarship of Excellence

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Research
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  1. (Charilaos Filippakis) Jan 15, 2019 - Jan 14, 2022
    The LAM Foundation
    Therapeutic targeting of macropinocytic nutrient uptake in LAM and TSC.
    Role: PI

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Filippakis H, Belaid A, Siroky B, Wu C, Alesi N, Hougard T, Nijmeh J, Lam HC, Henske EP. Vps34-mediated macropinocytosis in Tuberous Sclerosis Complex 2-deficient cells supports tumorigenesis. Sci Rep. 2018 09 21; 8(1):14161. PMID: 30242175.
    Citations:    Fields:    Translation:AnimalsCells
  2. Priolo C, Khabibullin D, Reznik E, Filippakis H, Ogórek B, Kavanagh TR, Nijmeh J, Herbert ZT, Asara JM, Kwiatkowski DJ, Wu CL, Henske EP. Impairment of gamma-glutamyl transferase 1 activity in the metabolic pathogenesis of chromophobe renal cell carcinoma. Proc Natl Acad Sci U S A. 2018 07 03; 115(27):E6274-E6282. PMID: 29891694.
    Citations: 8     Fields:    Translation:HumansCells
  3. Lam HC, Liu HJ, Baglini CV, Filippakis H, Alesi N, Nijmeh J, Du H, Lope AL, Cottrill KA, Handen A, Asara JM, Kwiatkowski DJ, Ben-Sahra I, Oldham WM, Chan SY, Henske EP. Rapamycin-induced miR-21 promotes mitochondrial homeostasis and adaptation in mTORC1 activated cells. Oncotarget. 2017 Sep 12; 8(39):64714-64727. PMID: 29029388.
    Citations: 6     Fields:    
  4. Filippakis H, Alesi N, Ogorek B, Nijmeh J, Khabibullin D, Gutierrez C, Valvezan AJ, Cunningham J, Priolo C, Henske EP. Lysosomal regulation of cholesterol homeostasis in tuberous sclerosis complex is mediated via NPC1 and LDL-R. Oncotarget. 2017 Jun 13; 8(24):38099-38112. PMID: 28498820.
    Citations: 4     Fields:    Translation:HumansCells
  5. Priolo C, Ricoult SJ, Khabibullin D, Filippakis H, Yu J, Manning BD, Clish C, Henske EP. Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis. Am J Respir Cell Mol Biol. 2015 Jul; 53(1):33-41. PMID: 25780943.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  6. Belaid A, Ndiaye PD, Filippakis H, Roux J, Röttinger É, Graba Y, Brest P, Hofman P, Mograbi B. Autophagy : Moving Benchside Promises to Patient Bedsides. Curr Cancer Drug Targets. 2015; 15(8):684-702. PMID: 26452384.
    Citations: 6     Fields:    Translation:Humans
  7. Hu L, Filippakis H, Huang H, Yen TJ, Gjoerup OV. Replication stress and mitotic dysfunction in cells expressing simian virus 40 large T antigen. J Virol. 2013 Dec; 87(24):13179-92. PMID: 24067972.
    Citations: 10     Fields:    Translation:HumansCells
  8. Filippakis H, Dimitropoulou P, Eliopoulos AG, Spandidos DA, Sourvinos G. The enhanced host-cell permissiveness of human cytomegalovirus is mediated by the Ras signaling pathway. Biochim Biophys Acta. 2011 Oct; 1813(10):1872-82. PMID: 21782855.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  9. Androutsopoulos VP, Ruparelia KC, Papakyriakou A, Filippakis H, Tsatsakis AM, Spandidos DA. Anticancer effects of the metabolic products of the resveratrol analogue, DMU-212: structural requirements for potency. Eur J Med Chem. 2011 Jun; 46(6):2586-95. PMID: 21497957.
    Citations: 15     Fields:    Translation:HumansCells
  10. Filippakis H, Spandidos DA, Sourvinos G. Herpesviruses: hijacking the Ras signaling pathway. Biochim Biophys Acta. 2010 Jul; 1803(7):777-85. PMID: 20303365.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.