Harvard Catalyst Profiles

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Jacob Garza, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K22NS094591 (GARZA, JACOB C) Sep 30, 2015 - Sep 29, 2018
    CRISPR/Cas9-Based Functional Characterization of ANK2 Mutations in ASD Neural Circuitry
    Role: Principal Investigator
  2. F31MH083442 (GARZA, JACOB C) May 1, 2008 - Apr 30, 2010
    Mechanisms underlying leptin's effects on adult hippocampal neurogenesis
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bowles KR, Silva MC, Whitney K, Bertucci T, Berlind JE, Lai JD, Garza JC, Boles NC, Mahali S, Strang KH, Marsh JA, Chen C, Pugh DA, Liu Y, Gordon RE, Goderie SK, Chowdhury R, Lotz S, Lane K, Crary JF, Haggarty SJ, Karch CM, Ichida JK, Goate AM, Temple S. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021 08 19; 184(17):4547-4563.e17. PMID: 34314701.
    Citations: 7     Fields:    Translation:HumansCells
  2. Riggs MJ, Garza JC. Neuropsychiatric Illness in the Age of Stem Cell Research. Stem Cells Dev. 2020 09 01; 29(17):1097-1098. PMID: 32877314.
    Citations:    Fields:    Translation:HumansCells
  3. Garza JC, Qi X, Gjeluci K, Leussis MP, Basu H, Reis SA, Zhao WN, Piguel NH, Penzes P, Haggarty SJ, Martens GJ, Poelmans G, Petryshen TL. Disruption of the psychiatric risk gene Ankyrin 3 enhances microtubule dynamics through GSK3/CRMP2 signaling. Transl Psychiatry. 2018 07 25; 8(1):135. PMID: 30046097.
    Citations: 11     Fields:    Translation:AnimalsCells
  4. Petryshen TL, Lewis MC, Dennehy KA, Garza JC, Fava M. Antidepressant-like effect of low dose ketamine and scopolamine co-treatment in mice. Neurosci Lett. 2016 05 04; 620:70-3. PMID: 27033002.
    Citations: 8     Fields:    Translation:Animals
  5. Guo M, Huang TY, Garza JC, Chua SC, Lu XY. Selective deletion of leptin receptors in adult hippocampus induces depression-related behaviours. Int J Neuropsychopharmacol. 2013 May; 16(4):857-67. PMID: 22932068.
    Citations: 45     Fields:    Translation:Animals
  6. Guo M, Lu Y, Garza JC, Li Y, Chua SC, Zhang W, Lu B, Lu XY. Forebrain glutamatergic neurons mediate leptin action on depression-like behaviors and synaptic depression. Transl Psychiatry. 2012; 2:e83. PMID: 22408745.
    Citations: 39     Fields:    Translation:AnimalsCells
  7. Garza JC, Guo M, Zhang W, Lu XY. Leptin increases adult hippocampal neurogenesis in vivo and in vitro. J Biol Chem. 2008 Jun 27; 283(26):18238-47. PMID: 18367451.
    Citations: 108     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.