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Barry Michael Zee, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Anastas JN, Zee BM, Kalin JH, Kim M, Guo R, Alexandrescu S, Blanco MA, Giera S, Gillespie SM, Das J, Wu M, Nocco S, Bonal DM, Nguyen QD, Suva ML, Bernstein BE, Alani R, Golub TR, Cole PA, Filbin MG, Shi Y. Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. 2019 11 11; 36(5):528-544.e10. PMID: 31631026.
  2. Dhall A, Zee BM, Yan F, Blanco MA. Intersection of Epigenetic and Metabolic Regulation of Histone Modifications in Acute Myeloid Leukemia. Front Oncol. 2019; 9:432. PMID: 31192132.
  3. Kang H, Jung YL, McElroy KA, Zee BM, Wallace HA, Woolnough JL, Park PJ, Kuroda MI. Bivalent complexes of PRC1 with orthologs of BRD4 and MOZ/MORF target developmental genes in Drosophila. Genes Dev. 2017 10 01; 31(19):1988-2002. PMID: 29070704.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  4. Alekseyenko AA, Walsh EM, Zee BM, Pakozdi T, Hsi P, Lemieux ME, Dal Cin P, Ince TA, Kharchenko PV, Kuroda MI, French CA. Ectopic protein interactions within BRD4-chromatin complexes drive oncogenic megadomain formation in NUT midline carcinoma. Proc Natl Acad Sci U S A. 2017 05 23; 114(21):E4184-E4192. PMID: 28484033.
    Citations: 4     Fields:    Translation:HumansCells
  5. McElroy KA, Jung YL, Zee BM, Wang CI, Park PJ, Kuroda MI. upSET, the Drosophila homologue of SET3, Is Required for Viability and the Proper Balance of Active and Repressive Chromatin Marks. G3 (Bethesda). 2017 02 09; 7(2):625-635. PMID: 28064188.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  6. Zee BM, Dibona AB, Alekseyenko AA, French CA, Kuroda MI. The Oncoprotein BRD4-NUT Generates Aberrant Histone Modification Patterns. PLoS One. 2016; 11(10):e0163820. PMID: 27698495.
    Citations: 2     Fields:    Translation:HumansCells
  7. Zee BM, Alekseyenko AA, McElroy KA, Kuroda MI. Streamlined discovery of cross-linked chromatin complexes and associated histone modifications by mass spectrometry. Proc Natl Acad Sci U S A. 2016 Feb 16; 113(7):1784-9. PMID: 26831069.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Kang H, McElroy KA, Jung YL, Alekseyenko AA, Zee BM, Park PJ, Kuroda MI. Sex comb on midleg (Scm) is a functional link between PcG-repressive complexes in Drosophila. Genes Dev. 2015 Jun 01; 29(11):1136-50. PMID: 26063573.
    Citations: 12     Fields:    Translation:AnimalsCells
  9. Won KJ, Choi I, LeRoy G, Zee BM, Sidoli S, Gonzales-Cope M, Garcia BA. Proteogenomics analysis reveals specific genomic orientations of distal regulatory regions composed by non-canonical histone variants. Epigenetics Chromatin. 2015; 8:13. PMID: 25878728.
    Citations: 3     Fields:    
  10. Alekseyenko AA, McElroy KA, Kang H, Zee BM, Kharchenko PV, Kuroda MI. BioTAP-XL: Cross-linking/Tandem Affinity Purification to Study DNA Targets, RNA, and Protein Components of Chromatin-Associated Complexes. Curr Protoc Mol Biol. 2015 Jan 05; 109:21.30.1-21.30.32. PMID: 25559106.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  11. Karch KR, Zee BM, Garcia BA. High resolution is not a strict requirement for characterization and quantification of histone post-translational modifications. J Proteome Res. 2014 Dec 05; 13(12):6152-9. PMID: 25325711.
    Citations: 3     Fields:    Translation:HumansCells
  12. Mews P, Zee BM, Liu S, Donahue G, Garcia BA, Berger SL. Histone methylation has dynamics distinct from those of histone acetylation in cell cycle reentry from quiescence. Mol Cell Biol. 2014 Nov; 34(21):3968-80. PMID: 25154414.
    Citations: 10     Fields:    Translation:AnimalsCells
  13. Alekseyenko AA, Gorchakov AA, Zee BM, Fuchs SM, Kharchenko PV, Kuroda MI. Heterochromatin-associated interactions of Drosophila HP1a with dADD1, HIPP1, and repetitive RNAs. Genes Dev. 2014 Jul 01; 28(13):1445-60. PMID: 24990964.
    Citations: 23     Fields:    Translation:AnimalsCells
  14. Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors. PLoS One. 2014; 9(4):e95535. PMID: 24740276.
    Citations: 2     Fields:    
  15. Smadbeck J, Peterson MB, Zee BM, Garapaty S, Mago A, Lee C, Giannis A, Trojer P, Garcia BA, Floudas CA. De novo peptide design and experimental validation of histone methyltransferase inhibitors. PLoS One. 2014; 9(2):e90095. PMID: 24587223.
    Citations: 4     Fields:    Translation:HumansCells
  16. Leroy G, Dimaggio PA, Chan EY, Zee BM, Blanco MA, Bryant B, Flaniken IZ, Liu S, Kang Y, Trojer P, Garcia BA. A quantitative atlas of histone modification signatures from human cancer cells. Epigenetics Chromatin. 2013 Jul 05; 6(1):20. PMID: 23826629.
    Citations: 32     Fields:    
  17. Stadler SC, Vincent CT, Fedorov VD, Patsialou A, Cherrington BD, Wakshlag JJ, Mohanan S, Zee BM, Zhang X, Garcia BA, Condeelis JS, Brown AM, Coonrod SA, Allis CD. Dysregulation of PAD4-mediated citrullination of nuclear GSK3ß activates TGF-ß signaling and induces epithelial-to-mesenchymal transition in breast cancer cells. Proc Natl Acad Sci U S A. 2013 Jul 16; 110(29):11851-6. PMID: 23818587.
    Citations: 20     Fields:    Translation:HumansCells
  18. Evertts AG, Zee BM, Dimaggio PA, Gonzales-Cope M, Coller HA, Garcia BA. Quantitative dynamics of the link between cellular metabolism and histone acetylation. J Biol Chem. 2013 Apr 26; 288(17):12142-51. PMID: 23482559.
    Citations: 33     Fields:    Translation:HumansCells
  19. Cao XJ, Zee BM, Garcia BA. Heavy methyl-SILAC labeling coupled with liquid chromatography and high-resolution mass spectrometry to study the dynamics of site-specific histone methylation. Methods Mol Biol. 2013; 977:299-313. PMID: 23436372.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  20. Zee BM, Garcia BA. Validation of protein acetylation by mass spectrometry. Methods Mol Biol. 2013; 981:1-11. PMID: 23381849.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  21. Voigt P, LeRoy G, Drury WJ, Zee BM, Son J, Beck DB, Young NL, Garcia BA, Reinberg D. Asymmetrically modified nucleosomes. Cell. 2012 Sep 28; 151(1):181-93. PMID: 23021224.
    Citations: 120     Fields:    Translation:HumansAnimalsCells
  22. LeRoy G, Chepelev I, DiMaggio PA, Blanco MA, Zee BM, Zhao K, Garcia BA. Proteogenomic characterization and mapping of nucleosomes decoded by Brd and HP1 proteins. Genome Biol. 2012 Aug 16; 13(8):R68. PMID: 22897906.
    Citations: 40     Fields:    Translation:HumansCells
  23. Blanco MA, LeRoy G, Khan Z, Aleckovic M, Zee BM, Garcia BA, Kang Y. Global secretome analysis identifies novel mediators of bone metastasis. Cell Res. 2012 Sep; 22(9):1339-55. PMID: 22688892.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  24. Pannorfi R, Zee BM, Vatnick I, Berner N, Hiebert SM. Dietary lipid saturation influences environmental temperature preference but not resting metabolic rate in the Djungarian Hamster (Phodopus sungorus). Physiol Biochem Zool. 2012 Jul-Aug; 85(4):405-14. PMID: 22705490.
    Citations: 1     Fields:    Translation:Animals
  25. Zee BM, Britton LM, Wolle D, Haberman DM, Garcia BA. Origins and formation of histone methylation across the human cell cycle. Mol Cell Biol. 2012 Jul; 32(13):2503-14. PMID: 22547680.
    Citations: 28     Fields:    Translation:HumansCells
  26. Zee BM, Garcia BA. Discovery of lysine post-translational modifications through mass spectrometric detection. Essays Biochem. 2012; 52:147-63. PMID: 22708569.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  27. Kuo AJ, Cheung P, Chen K, Zee BM, Kioi M, Lauring J, Xi Y, Park BH, Shi X, Garcia BA, Li W, Gozani O. NSD2 links dimethylation of histone H3 at lysine 36 to oncogenic programming. Mol Cell. 2011 Nov 18; 44(4):609-20. PMID: 22099308.
    Citations: 107     Fields:    Translation:HumansAnimalsCells
  28. Britton LM, Gonzales-Cope M, Zee BM, Garcia BA. Breaking the histone code with quantitative mass spectrometry. Expert Rev Proteomics. 2011 Oct; 8(5):631-43. PMID: 21999833.
    Citations: 44     Fields:    Translation:HumansCells
  29. Torrente MP, Zee BM, Young NL, Baliban RC, LeRoy G, Floudas CA, Hake SB, Garcia BA. Proteomic interrogation of human chromatin. PLoS One. 2011; 6(9):e24747. PMID: 21935452.
    Citations: 13     Fields:    Translation:HumansCells
  30. Zee BM, Young NL, Garcia BA. Quantitative proteomic approaches to studying histone modifications. Curr Chem Genomics. 2011; 5(Suppl 1):106-14. PMID: 21966350.
    Citations: 5     
  31. Wu L, Zee BM, Wang Y, Garcia BA, Dou Y. The RING finger protein MSL2 in the MOF complex is an E3 ubiquitin ligase for H2B K34 and is involved in crosstalk with H3 K4 and K79 methylation. Mol Cell. 2011 Jul 08; 43(1):132-44. PMID: 21726816.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  32. Hergeth SP, Dundr M, Tropberger P, Zee BM, Garcia BA, Daujat S, Schneider R. Isoform-specific phosphorylation of human linker histone H1.4 in mitosis by the kinase Aurora B. J Cell Sci. 2011 May 15; 124(Pt 10):1623-8. PMID: 21511733.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  33. Zee BM, Levin RS, DiMaggio PA, Garcia BA. Global turnover of histone post-translational modifications and variants in human cells. Epigenetics Chromatin. 2010 Dec 06; 3(1):22. PMID: 21134274.
    Citations: 56     Fields:    
  34. Levy D, Kuo AJ, Chang Y, Schaefer U, Kitson C, Cheung P, Espejo A, Zee BM, Liu CL, Tangsombatvisit S, Tennen RI, Kuo AY, Tanjing S, Cheung R, Chua KF, Utz PJ, Shi X, Prinjha RK, Lee K, Garcia BA, Bedford MT, Tarakhovsky A, Cheng X, Gozani O. Lysine methylation of the NF-?B subunit RelA by SETD6 couples activity of the histone methyltransferase GLP at chromatin to tonic repression of NF-?B signaling. Nat Immunol. 2011 Jan; 12(1):29-36. PMID: 21131967.
    Citations: 94     Fields:    Translation:HumansCells
  35. Weiss T, Hergeth S, Zeissler U, Izzo A, Tropberger P, Zee BM, Dundr M, Garcia BA, Daujat S, Schneider R. Histone H1 variant-specific lysine methylation by G9a/KMT1C and Glp1/KMT1D. Epigenetics Chromatin. 2010 Mar 24; 3(1):7. PMID: 20334638.
    Citations: 37     Fields:    
  36. Evertts AG, Zee BM, Garcia BA. Modern approaches for investigating epigenetic signaling pathways. J Appl Physiol (1985). 2010 Sep; 109(3):927-33. PMID: 20110548.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  37. Zee BM, Garcia BA. Electron transfer dissociation facilitates sequencing of adenosine diphosphate-ribosylated peptides. Anal Chem. 2010 Jan 01; 82(1):28-31. PMID: 19928949.
    Citations: 8     Fields:    Translation:Cells
  38. Zee BM, Levin RS, Xu B, LeRoy G, Wingreen NS, Garcia BA. In vivo residue-specific histone methylation dynamics. J Biol Chem. 2010 Jan 29; 285(5):3341-50. PMID: 19940157.
    Citations: 100     Fields:    Translation:HumansCells
  39. Plazas-Mayorca MD, Zee BM, Young NL, Fingerman IM, LeRoy G, Briggs SD, Garcia BA. One-pot shotgun quantitative mass spectrometry characterization of histones. J Proteome Res. 2009 Nov; 8(11):5367-74. PMID: 19764812.
    Citations: 69     Fields:    Translation:HumansCells
  40. LeRoy G, Weston JT, Zee BM, Young NL, Plazas-Mayorca MD, Garcia BA. Heterochromatin protein 1 is extensively decorated with histone code-like post-translational modifications. Mol Cell Proteomics. 2009 Nov; 8(11):2432-42. PMID: 19567367.
    Citations: 43     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.