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Rajindra P Aryal, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zeng J, Aryal RP, Stavenhagen K, Luo C, Liu R, Wang X, Chen J, Li H, Matsumoto Y, Wang Y, Wang J, Ju T, Cummings RD. Cosmc deficiency causes spontaneous autoimmunity by breaking B cell tolerance. Sci Adv. 2021 Oct 08; 7(41):eabg9118. PMID: 34613773; PMCID: PMC8494437.
    Citations: 1     Fields:    
  2. Zeng J, Eljalby M, Aryal RP, Lehoux S, Stavenhagen K, Kudelka MR, Wang Y, Wang J, Ju T, von Andrian UH, Cummings RD. Cosmc controls B cell homing. Nat Commun. 2020 08 10; 11(1):3990. PMID: 32778659.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  3. McKitrick TR, Eris D, Mondal N, Aryal RP, McCurley N, Heimburg-Molinaro J, Cummings RD. Antibodies from Lampreys as Smart Anti-Glycan Reagents (SAGRs): Perspectives on Their Specificity, Structure, and Glyco-genomics. Biochemistry. 2020 09 01; 59(34):3111-3122. PMID: 32052624.
    Citations: 10     Fields:    Translation:HumansAnimals
  4. Aryal RP, Kwak PB, Tamayo AG, Gebert M, Chiu PL, Walz T, Weitz CJ. Macromolecular Assemblies of the Mammalian Circadian Clock. Mol Cell. 2017 Sep 07; 67(5):770-782.e6. PMID: 28886335; PMCID: PMC5679067.
    Citations: 85     Fields:    Translation:AnimalsCells
  5. Lehoux S, Mi R, Aryal RP, Wang Y, Schjoldager KT, Clausen H, van Die I, Han Y, Chapman AB, Cummings RD, Ju T. Identification of distinct glycoforms of IgA1 in plasma from patients with immunoglobulin A (IgA) nephropathy and healthy individuals. Mol Cell Proteomics. 2014 Nov; 13(11):3097-113. PMID: 25071157.
    Citations: 14     Fields:    Translation:HumansCells
  6. Aryal RP, Ju T, Cummings RD. Identification of a novel protein binding motif within the T-synthase for the molecular chaperone Cosmc. J Biol Chem. 2014 Apr 25; 289(17):11630-11641. PMID: 24616093.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  7. Ju T, Aryal RP, Kudelka MR, Wang Y, Cummings RD. The Cosmc connection to the Tn antigen in cancer. Cancer Biomark. 2014 Jan 01; 14(1):63-81. PMID: 24643043.
    Citations: 57     Fields:    Translation:HumansAnimalsCells
  8. Ju T, Wang Y, Aryal RP, Lehoux SD, Ding X, Kudelka MR, Cutler C, Zeng J, Wang J, Sun X, Heimburg-Molinaro J, Smith DF, Cummings RD. Tn and sialyl-Tn antigens, aberrant O-glycomics as human disease markers. Proteomics Clin Appl. 2013 Oct; 7(9-10):618-31. PMID: 23857728.
    Citations: 57     Fields:    Translation:HumansAnimals
  9. Gao Y, Aryal RP, Ju T, Cummings RD, Gahlay G, Jarvis DL, Matta KL, Vlahakis JZ, Szarek WA, Brockhausen I. Acceptor specificities and selective inhibition of recombinant human Gal- and GlcNAc-transferases that synthesize core structures 1, 2, 3 and 4 of O-glycans. Biochim Biophys Acta. 2013 Aug; 1830(8):4274-81. PMID: 23578692.
    Citations: 4     Fields:    Translation:HumansCells
  10. Mi R, Song L, Wang Y, Ding X, Zeng J, Lehoux S, Aryal RP, Wang J, Crew VK, van Die I, Chapman AB, Cummings RD, Ju T. Epigenetic silencing of the chaperone Cosmc in human leukocytes expressing tn antigen. J Biol Chem. 2012 Nov 30; 287(49):41523-33. PMID: 23035125.
    Citations: 40     Fields:    Translation:HumansCells
  11. Aryal RP, Ju T, Cummings RD. Tight complex formation between Cosmc chaperone and its specific client non-native T-synthase leads to enzyme activity and client-driven dissociation. J Biol Chem. 2012 May 04; 287(19):15317-29. PMID: 22416136.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  12. Ju T, Xia B, Aryal RP, Wang W, Wang Y, Ding X, Mi R, He M, Cummings RD. A novel fluorescent assay for T-synthase activity. Glycobiology. 2011 Mar; 21(3):352-62. PMID: 20959392.
    Citations: 22     Fields:    Translation:HumansCells
  13. Aryal RP, Ju T, Cummings RD. The endoplasmic reticulum chaperone Cosmc directly promotes in vitro folding of T-synthase. J Biol Chem. 2010 Jan 22; 285(4):2456-62. PMID: 19923218.
    Citations: 39     Fields:    Translation:HumansCells
  14. Ju T, Aryal RP, Stowell CJ, Cummings RD. Regulation of protein O-glycosylation by the endoplasmic reticulum-localized molecular chaperone Cosmc. J Cell Biol. 2008 Aug 11; 182(3):531-42. PMID: 18695044; PMCID: PMC2500138.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.