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Jakob Tobias Sieker, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sieker JT, Horowitz C, Hu CK, Lacombe-Daphnis M, Chirokas B, Pina C, Heger NE, Rabson AR, Zhou M, Bogen SA, Horowitz GL. Analytic Sensitivity of 3 Nucleic Acid Detection Assays in Diagnosis of SARS-CoV-2 Infection. J Appl Lab Med. 2021 03 01; 6(2):421-428. PMID: 33674879.
    Citations: 1     Fields:    Translation:Humans
  2. Karamchedu NP, Murray MM, Sieker JT, Proffen BL, Portilla G, Costa MQ, Molino J, Fleming BC. Bridge-Enhanced Anterior Cruciate Ligament Repair Leads to Greater Limb Asymmetry and Less Cartilage Damage Than Untreated ACL Transection or ACL Reconstruction in the Porcine Model. Am J Sports Med. 2021 03; 49(3):667-674. PMID: 33534613.
    Citations:    Fields:    Translation:Animals
  3. Dower J, Dima D, Sieker J, Pilichowska M, Varga C. Eculizumab-induced late erythroid maturation arrest: a case report. Br J Haematol. 2020 10; 191(1):120-122. PMID: 32671821.
    Citations: 1     Fields:    Translation:HumansCells
  4. Voss A, Andreß B, Pauzenberger L, Herbst E, Pogorzelski J, John D, Smolen D, Roessler PP, Tobert DG, Sieker JT. Research productivity during orthopedic surgery residency correlates with pre-planned and protected research time: a survey of German-speaking countries. Knee Surg Sports Traumatol Arthrosc. 2021 Jan; 29(1):292-299. PMID: 32303802.
    Citations:    Fields:    Translation:Humans
  5. Richard D, Liu Z, Cao J, Kiapour AM, Willen J, Yarlagadda S, Jagoda E, Kolachalama VB, Sieker JT, Chang GH, Muthuirulan P, Young M, Masson A, Konrad J, Hosseinzadeh S, Maridas DE, Rosen V, Krawetz R, Roach N, Capellini TD. Evolutionary Selection and Constraint on Human Knee Chondrocyte Regulation Impacts Osteoarthritis Risk. Cell. 2020 04 16; 181(2):362-381.e28. PMID: 32220312.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  6. Ayturk UM, Sieker JT, Haslauer CM, Proffen BL, Weissenberger MH, Warman ML, Fleming BC, Murray MM. Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis. PLoS One. 2020; 15(2):e0229449. PMID: 32107493.
    Citations: 1     Fields:    Translation:AnimalsCells
  7. Gardner OF, Juneja SC, Whetstone H, Nartiss Y, Sieker JT, Veillette C, Keller GM, Craft AM. Effective repair of articular cartilage using human pluripotent stem cell-derived tissue. Eur Cell Mater. 2019 11 05; 38:215-227. PMID: 31688947.
    Citations:    Fields:    Translation:HumansAnimalsCells
  8. Beveridge JE, Proffen BL, Karamchedu NP, Chin KE, Sieker JT, Badger GJ, Kiapour AM, Murray MM, Fleming BC. Cartilage Damage Is Related to ACL Stiffness in a Porcine Model of ACL Repair. J Orthop Res. 2019 10; 37(10):2249-2257. PMID: 31125133.
    Citations: 1     Fields:    Translation:Animals
  9. Kiapour AM, Sieker JT, Proffen BL, Lam TT, Fleming BC, Murray MM. Synovial fluid proteome changes in ACL injury-induced posttraumatic osteoarthritis: Proteomics analysis of porcine knee synovial fluid. PLoS One. 2019; 14(3):e0212662. PMID: 30822327.
    Citations: 1     Fields:    Translation:Animals
  10. Prager P, Kunz M, Ebert R, Klein-Hitpass L, Sieker J, Barthel T, Jakob F, Konrads C, Steinert A. Mesenchymal Stem Cells Isolated from the Anterior Cruciate Ligament: Characterization and Comparison of Cells from Young and Old Donors. Knee Surg Relat Res. 2018 Sep 01; 30(3):193-205. PMID: 29554721.
    Citations: 5     
  11. Dhingra R, Rai P, Sieker J, Roper J. Myxedema Ascites: An Unusual Presentation of Uncontrolled Hypothyroidism. Cureus. 2018 May 14; 10(5):e2627. PMID: 30027019.
  12. Sieker JT, Proffen BL, Waller KA, Chin KE, Karamchedu NP, Akelman MR, Perrone GS, Kiapour AM, Konrad J, Fleming BC, Murray MM. Transcriptional profiling of synovium in a porcine model of early post-traumatic osteoarthritis. J Orthop Res. 2018 Feb 20. PMID: 29460983.
    Citations: 3     Fields:    
  13. Beveridge JE, Machan JT, Walsh EG, Kiapour AM, Karamchedu NP, Chin KE, Proffen BL, Sieker JT, Murray MM, Fleming BC. Magnetic resonance measurements of tissue quantity and quality using T2 * relaxometry predict temporal changes in the biomechanical properties of the healing ACL. J Orthop Res. 2018 06; 36(6):1701-1709. PMID: 29227559.
    Citations: 11     Fields:    Translation:Animals
  14. Sieker JT, Proffen BL, Waller KA, Chin KE, Karamchedu NP, Akelman MR, Perrone GS, Kiapour AM, Konrad J, Murray MM, Fleming BC. Transcriptional profiling of articular cartilage in a porcine model of early post-traumatic osteoarthritis. J Orthop Res. 2018 01; 36(1):318-329. PMID: 28671352.
    Citations: 6     Fields:    Translation:Animals
  15. Perrone GS, Proffen BL, Kiapour AM, Sieker JT, Fleming BC, Murray MM. Bench-to-bedside: Bridge-enhanced anterior cruciate ligament repair. J Orthop Res. 2017 12; 35(12):2606-2612. PMID: 28608618.
    Citations: 7     Fields:    Translation:HumansAnimals
  16. Sieker JT, Ayturk UM, Proffen BL, Weissenberger MH, Kiapour AM, Murray MM. Immediate Administration of Intraarticular Triamcinolone Acetonide After Joint Injury Modulates Molecular Outcomes Associated With Early Synovitis. Arthritis Rheumatol. 2016 07; 68(7):1637-47. PMID: 26866935.
    Citations: 9     Fields:    Translation:Animals
  17. Proffen BL, Sieker JT, Murray MM, Akelman MR, Chin KE, Perrone GS, Patel TK, Fleming BC. Extracellular matrix-blood composite injection reduces post-traumatic osteoarthritis after anterior cruciate ligament injury in the rat. J Orthop Res. 2016 06; 34(6):995-1003. PMID: 26629963.
    Citations: 3     Fields:    Translation:Animals
  18. Proffen BL, Perrone GS, Fleming BC, Sieker JT, Kramer J, Hawes ML, Murray MM. Effect of low-temperature ethylene oxide and electron beam sterilization on the in vitro and in vivo function of reconstituted extracellular matrix-derived scaffolds. J Biomater Appl. 2015 Oct; 30(4):435-49. PMID: 26088294.
    Citations: 6     Fields:    Translation:AnimalsCellsPHPublic Health
  19. Proffen BL, Perrone GS, Fleming BC, Sieker JT, Kramer J, Hawes ML, Badger GJ, Murray MM. Electron beam sterilization does not have a detrimental effect on the ability of extracellular matrix scaffolds to support in vivo ligament healing. J Orthop Res. 2015 Jul; 33(7):1015-23. PMID: 25676876.
    Citations: 7     Fields:    Translation:AnimalsCellsPHPublic Health
  20. Proffen BL, Sieker JT, Murray MM. Bio-enhanced repair of the anterior cruciate ligament. Arthroscopy. 2015 May; 31(5):990-7. PMID: 25595694.
    Citations: 13     Fields:    Translation:HumansAnimals
  21. Sieker JT, Kunz M, Weißenberger M, Gilbert F, Frey S, Rudert M, Steinert AF. Direct bone morphogenetic protein 2 and Indian hedgehog gene transfer for articular cartilage repair using bone marrow coagulates. Osteoarthritis Cartilage. 2015 Mar; 23(3):433-42. PMID: 25463442.
    Citations: 11     Fields:    Translation:AnimalsCells
  22. Sieker JT, Rudert M, Steinert AF. Symptomatic loosening of a total knee arthroplasty caused by a tibial chondrosarcoma - a case report. Springerplus. 2014; 3:308. PMID: 24995155.
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.