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Halil-Ibrahim Aksoylar, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Aksoylar HI, Boussiotis VA. PD-1+ Treg cells: a foe in cancer immunotherapy? Nat Immunol. 2020 11; 21(11):1311-1312. PMID: 32973361.
    Citations: 2     Fields:    Translation:HumansCells
  2. Bardhan K, Aksoylar HI, Le Bourgeois T, Strauss L, Weaver JD, Delcuze B, Charest A, Patsoukis N, Boussiotis VA. Publisher Correction: Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells. Sci Rep. 2020 Sep 23; 10(1):15905. PMID: 32963251.
    Citations:    Fields:    
  3. Aksoylar HI, Tijaro-Ovalle NM, Boussiotis VA, Patsoukis N. T Cell Metabolism in Cancer Immunotherapy. Immunometabolism. 2020; 2(3). PMID: 32642279.
    Citations: 4     
  4. Patsoukis N, Duke-Cohan JS, Chaudhri A, Aksoylar HI, Wang Q, Council A, Berg A, Freeman GJ, Boussiotis VA. Interaction of SHP-2 SH2 domains with PD-1 ITSM induces PD-1 dimerization and SHP-2 activation. Commun Biol. 2020 03 17; 3(1):128. PMID: 32184441.
    Citations: 8     
  5. Bardhan K, Aksoylar HI, Le Bourgeois T, Strauss L, Weaver JD, Delcuze B, Charest A, Patsoukis N, Boussiotis VA. Phosphorylation of PD-1-Y248 is a marker of PD-1-mediated inhibitory function in human T cells. Sci Rep. 2019 11 21; 9(1):17252. PMID: 31754127.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  6. Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T. Author Correction: Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses. Nat Immunol. 2019 Nov; 20(11):1555. PMID: 31551573.
    Citations: 1     Fields:    
  7. Langston PK, Nambu A, Jung J, Shibata M, Aksoylar HI, Lei J, Xu P, Doan MT, Jiang H, MacArthur MR, Gao X, Kong Y, Chouchani ET, Locasale JW, Snyder NW, Horng T. Glycerol phosphate shuttle enzyme GPD2 regulates macrophage inflammatory responses. Nat Immunol. 2019 09; 20(9):1186-1195. PMID: 31384058.
    Citations: 19     Fields:    Translation:AnimalsCells
  8. Yazicioglu YF, Aksoylar HI, Pal R, Patsoukis N, Boussiotis VA. Unraveling Key Players of Humoral Immunity: Advanced and Optimized Lymphocyte Isolation Protocol from Murine Peyer's Patches. J Vis Exp. 2018 11 21; (141). PMID: 30531720.
    Citations:    Fields:    Translation:AnimalsCells
  9. Le Bourgeois T, Strauss L, Aksoylar HI, Daneshmandi S, Seth P, Patsoukis N, Boussiotis VA. Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy. Front Oncol. 2018; 8:237. PMID: 30123774.
    Citations: 38     
  10. Patterson AR, Endale M, Lampe K, Aksoylar HI, Flagg A, Woodgett JR, Hildeman D, Jordan MB, Singh H, Kucuk Z, Bleesing J, Hoebe K. Gimap5-dependent inactivation of GSK3ß is required for CD4+ T cell homeostasis and prevention of immune pathology. Nat Commun. 2018 01 30; 9(1):430. PMID: 29382851.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  11. Covarrubias AJ, Aksoylar HI, Yu J, Snyder NW, Worth AJ, Iyer SS, Wang J, Ben-Sahra I, Byles V, Polynne-Stapornkul T, Espinosa EC, Lamming D, Manning BD, Zhang Y, Blair IA, Horng T. Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation. Elife. 2016 Feb 19; 5. PMID: 26894960.
    Citations: 97     Fields:    Translation:AnimalsCells
  12. Covarrubias AJ, Aksoylar HI, Horng T. Control of macrophage metabolism and activation by mTOR and Akt signaling. Semin Immunol. 2015 Aug; 27(4):286-96. PMID: 26360589.
    Citations: 64     Fields:    Translation:HumansAnimalsCells
  13. Endale M, Aksoylar HI, Hoebe K. Central role of gimap5 in maintaining peripheral tolerance and T cell homeostasis in the gut. Mediators Inflamm. 2015; 2015:436017. PMID: 25944983.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  14. Aksoylar HI, Lampe K, Barnes MJ, Plas DR, Hoebe K. Loss of immunological tolerance in Gimap5-deficient mice is associated with loss of Foxo in CD4+ T cells. J Immunol. 2012 Jan 01; 188(1):146-54. PMID: 22106000.
    Citations: 15     Fields:    Translation:AnimalsCells
  15. Barnes MJ, Aksoylar H, Krebs P, Bourdeau T, Arnold CN, Xia Y, Khovananth K, Engel I, Sovath S, Lampe K, Laws E, Saunders A, Butcher GW, Kronenberg M, Steinbrecher K, Hildeman D, Grimes HL, Beutler B, Hoebe K. Loss of T cell and B cell quiescence precedes the onset of microbial flora-dependent wasting disease and intestinal inflammation in Gimap5-deficient mice. J Immunol. 2010 Apr 01; 184(7):3743-54. PMID: 20190135.
    Citations: 36     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.