Xianjun Dong, Ph.D.
|Title||Instructor in Neurology|
|Institution||Brigham and Women's Hospital|
|Address||Brigham and Women|
60 Fenwood Rd
Boston MA 02115
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|2010||Chinese Government Award for Outstanding Self-financed Students Abroad;|
|2000||Liu Yonglin Fellowship, Southeast University|
|2000||2nd prize in the National Undergraduate Mathematical Contest in Modelling|
|2000||Honour Student, Southeast University|
|2001||1st prize (Meritorious) in the international Interdisciplinary Contest in Modelling|
|2002||Honour Graduate, Southeast University|
|2002||1st prize in the 2002 National Undergraduate Electronic Design Contest;|
|2009||Scholarship for “Chromatin Domains and Insulators” workshop|
|2009||MCB Travel Fellowship, University of Bergen|
Dr. Dong is a computational biologist with more than 10 years of research experience. His research interests include developing and applying computational algorithms to integrate and analyze genomics and next-generation sequencing (NGS) data in order to provide better understanding of molecular mechanisms and biological processes that underlie development and diseases. Before his PhD, he was trained in Biomedical Engineering in both Bachelor and Master. He took his PhD with Dr. Lenhard Boris by studying transcriptional gene regulation in vertebrate genomes. He discovered a list of novel regulatory elements (i.e. enhancers) coupled in coding exons, by using the methods of comparative genomics and epigenomics. Later he did a postdoctoral research with Prof. Weng Zhiping in UMass Medical School, where he has exclusively involved in the scale-up phase of the ENCODE Project, specifically by modeling gene expression with various genomic and epigenomics features (e.g. H3K4me3, H3K36, H3K79 etc.) in various cellular context. He has also had fun in the world of small RNA, esp. piRNA and miRNA, in studying their roles in development and in neuronal disease. Recently he moved to Brigham and Women's Hospital and Harvard Medical School and worked as a bioinformatics lead in Dr. Scherzer Clemens's neurogenomics lab. The main interest of Dr. Dong's research is to understand both the structure and the function of brain genome of patients with Parkinson's disease, by analyzing NGS data like RNA-seq, genotyping, genome sequencing etc..
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