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Peter Jacob Fried, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01AG070077 (FRIED, PETER J) Mar 1, 2021 - Feb 28, 2026
    Neurobiological mechanisms of altered cortical plasticity in Type-2 diabetes mellitus
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Sherazi SAM, Abbasi A, Jamil A, Uzair M, Ikram A, Qamar S, Olamide AA, Arshad M, Fried PJ, Ljubisavljevic M, Wang R, Bashir S. Molecular hallmarks of long non-coding RNAs in aging and its significant effect on aging-associated diseases. Neural Regen Res. 2023 May; 18(5):959-968. PMID: 36254975.
  2. Di Lorenzo F, Oliviero A, Guerra A, Fried PJ. Editorial: Non-invasive Brain Stimulation for Neurodegenerative Disorders: From Investigation to Therapeutic Application. Front Neurol. 2022; 13:820942. PMID: 35309570; PMCID: PMC8929759.
  3. Hinchman CA, Fried PJ, Jannati A, Press DZ, Pascual-Leone A, Stern AP. Corticomotor plasticity as a predictor of response to high frequency transcranial magnetic stimulation treatment for major depressive disorder. J Affect Disord. 2022 04 15; 303:114-122. PMID: 35139416.
    Citations:    Fields:    Translation:Humans
  4. Ross JM, Ozdemir RA, Lian SJ, Fried PJ, Schmitt EM, Inouye SK, Pascual-Leone A, Shafi MM. A structured ICA-based process for removing auditory evoked potentials. Sci Rep. 2022 01 26; 12(1):1391. PMID: 35082350; PMCID: PMC8791940.
    Citations: 1     Fields:    Translation:Humans
  5. Cabral DF, Fried P, Koch S, Rice J, Rundek T, Pascual-Leone A, Sacco R, Wright CB, Gomes-Osman J. Efficacy of mechanisms of neuroplasticity after a stroke. Restor Neurol Neurosci. 2022; 40(2):73-84. PMID: 35570503.
    Citations:    Fields:    Translation:Humans
  6. Boucher PO, Ozdemir RA, Momi D, Burke MJ, Jannati A, Fried PJ, Pascual-Leone A, Shafi MM, Santarnecchi E. Sham-derived effects and the minimal reliability of theta burst stimulation. Sci Rep. 2021 10 27; 11(1):21170. PMID: 34707206; PMCID: PMC8551312.
    Citations:    Fields:    Translation:HumansCells
  7. Corp DT, Bereznicki HGK, Clark GM, Youssef GJ, Fried PJ, Jannati A, Davies CB, Gomes-Osman J, Kirkovski M, Albein-Urios N, Fitzgerald PB, Koch G, Di Lazzaro V, Pascual-Leone A, Enticott PG. Large-scale analysis of interindividual variability in single and paired-pulse TMS data. Clin Neurophysiol. 2021 10; 132(10):2639-2653. PMID: 34344609.
    Citations: 5     Fields:    Translation:Humans
  8. Zadey S, Buss SS, McDonald K, Press DZ, Pascual-Leone A, Fried PJ. Higher motor cortical excitability linked to greater cognitive dysfunction in Alzheimer's disease: results from two independent cohorts. Neurobiol Aging. 2021 12; 108:24-33. PMID: 34479168; PMCID: PMC8616846.
    Citations: 2     Fields:    Translation:Humans
  9. Ozdemir RA, Boucher P, Fried PJ, Momi D, Jannati A, Pascual-Leone A, Santarnecchi E, Shafi MM. Reproducibility of cortical response modulation induced by intermittent and continuous theta-burst stimulation of the human motor cortex. Brain Stimul. 2021 Jul-Aug; 14(4):949-964. PMID: 34126233.
    Citations: 5     Fields:    Translation:Humans
  10. Fried PJ, Santarnecchi E, Antal A, Bartres-Faz D, Bestmann S, Carpenter LL, Celnik P, Edwards D, Farzan F, Fecteau S, George MS, He B, Kim YH, Leocani L, Lisanby SH, Loo C, Luber B, Nitsche MA, Paulus W, Rossi S, Rossini PM, Rothwell J, Sack AT, Thut G, Ugawa Y, Ziemann U, Hallett M, Pascual-Leone A. Training in the practice of noninvasive brain stimulation: Recommendations from an IFCN committee. Clin Neurophysiol. 2021 03; 132(3):819-837. PMID: 33549501.
    Citations: 5     Fields:    Translation:Humans
  11. Buss SS, Press DZ, McDonald K, Kitchener E, O'Connor M, Donohoe K, Shafi MM, Pascual-Leone A, Fried PJ. LTP-like plasticity is impaired in amyloid-positive amnestic MCI but independent of PET-amyloid burden. Neurobiol Aging. 2020 12; 96:109-116. PMID: 33002764.
    Citations: 1     Fields:    Translation:Humans
  12. Corp DT, Bereznicki HGK, Clark GM, Youssef GJ, Fried PJ, Jannati A, Davies CB, Gomes-Osman J, Stamm J, Chung SW, Bowe SJ, Rogasch NC, Fitzgerald PB, Koch G, Di Lazzaro V, Pascual-Leone A, Enticott PG. Large-scale analysis of interindividual variability in theta-burst stimulation data: Results from the 'Big TMS Data Collaboration'. Brain Stimul. 2020 Sep - Oct; 13(5):1476-1488. PMID: 32758665.
    Citations: 20     Fields:    Translation:Humans
  13. Brem AK, Di Iorio R, Fried PJ, Oliveira-Maia AJ, Marra C, Profice P, Quaranta D, Schilberg L, Atkinson NJ, Seligson EE, Rossini PM, Pascual-Leone A. Corticomotor Plasticity Predicts Clinical Efficacy of Combined Neuromodulation and Cognitive Training in Alzheimer's Disease. Front Aging Neurosci. 2020; 12:200. PMID: 32733232; PMCID: PMC7360860.
    Citations: 9     
  14. Shaafi Kabiri N, Brooks C, Comery T, Kelley ME, Fried P, Bhangu J, Thomas K. The Hawthorne Effect in Eye-blinking: Awareness that One's Blinks are Being Counted Alters Blink Behavior. Curr Eye Res. 2020 11; 45(11):1380-1384. PMID: 32272023.
    Citations: 1     Fields:    Translation:Humans
  15. Morris TP, Fried PJ, Macone J, Stillman A, Gomes-Osman J, Costa-Miserachs D, Tormos Muñoz JM, Santarnecchi E, Pascual-Leone A. Light aerobic exercise modulates executive function and cortical excitability. Eur J Neurosci. 2020 04; 51(7):1723-1734. PMID: 31605625.
    Citations: 7     Fields:    Translation:Humans
  16. Benwell CSY, Davila-Pérez P, Fried PJ, Jones RN, Travison TG, Santarnecchi E, Pascual-Leone A, Shafi MM. EEG spectral power abnormalities and their relationship with cognitive dysfunction in patients with Alzheimer's disease and type 2 diabetes. Neurobiol Aging. 2020 01; 85:83-95. PMID: 31727363.
    Citations: 12     Fields:    
  17. Morris TP, Davila-Pérez P, Jannati A, Menardi A, Pascual-Leone A, Fried PJ. Aftereffects of Intermittent Theta-Burst Stimulation in Adjacent, Non-Target Muscles. Neuroscience. 2019 10 15; 418:157-165. PMID: 31476358.
    Citations: 3     Fields:    Translation:Humans
  18. Fried PJ, Pascual-Leone A, Bolo NR. Diabetes and the link between neuroplasticity and glutamate in the aging human motor cortex. Clin Neurophysiol. 2019 09; 130(9):1502-1510. PMID: 31295719.
    Citations: 5     Fields:    Translation:Humans
  19. Jannati A, Fried PJ, Block G, Oberman LM, Rotenberg A, Pascual-Leone A. Test-Retest Reliability of the Effects of Continuous Theta-Burst Stimulation. Front Neurosci. 2019; 13:447. PMID: 31156361; PMCID: PMC6533847.
    Citations: 15     
  20. Buss SS, Fried PJ, Pascual-Leone A. Therapeutic noninvasive brain stimulation in Alzheimer's disease and related dementias. Curr Opin Neurol. 2019 04; 32(2):292-304. PMID: 30720478.
    Citations: 18     Fields:    Translation:Humans
  21. Burke MJ, Fried PJ, Pascual-Leone A. Transcranial magnetic stimulation: Neurophysiological and clinical applications. Handb Clin Neurol. 2019; 163:73-92. PMID: 31590749.
    Citations: 14     Fields:    Translation:Humans
  22. Davila-Pérez P, Jannati A, Fried PJ, Cudeiro Mazaira J, Pascual-Leone A. The Effects of Waveform and Current Direction on the Efficacy and Test-Retest Reliability of Transcranial Magnetic Stimulation. Neuroscience. 2018 11 21; 393:97-109. PMID: 30300705.
    Citations: 15     Fields:    Translation:Humans
  23. Gomes-Osman J, Indahlastari A, Fried PJ, Cabral DLF, Rice J, Nissim NR, Aksu S, McLaren ME, Woods AJ. Non-invasive Brain Stimulation: Probing Intracortical Circuits and Improving Cognition in the Aging Brain. Front Aging Neurosci. 2018; 10:177. PMID: 29950986.
    Citations: 19     
  24. Buss SS, Padmanabhan J, Saxena S, Pascual-Leone A, Fried PJ. Atrophy in Distributed Networks Predicts Cognition in Alzheimer's Disease and Type 2 Diabetes. J Alzheimers Dis. 2018; 65(4):1301-1312. PMID: 30149455.
    Citations: 5     Fields:    Translation:Humans
  25. Menardi A, Pascual-Leone A, Fried PJ, Santarnecchi E. The Role of Cognitive Reserve in Alzheimer's Disease and Aging: A Multi-Modal Imaging Review. J Alzheimers Dis. 2018; 66(4):1341-1362. PMID: 30507572; PMCID: PMC8972845.
    Citations: 11     Fields:    Translation:Humans
  26. Gedankien T, Fried PJ, Pascual-Leone A, Shafi MM. Intermittent theta-burst stimulation induces correlated changes in cortical and corticospinal excitability in healthy older subjects. Clin Neurophysiol. 2017 12; 128(12):2419-2427. PMID: 29096215.
    Citations: 6     Fields:    Translation:Humans
  27. Fried PJ, Jannati A, Davila-Pérez P, Pascual-Leone A. Reproducibility of Single-Pulse, Paired-Pulse, and Intermittent Theta-Burst TMS Measures in Healthy Aging, Type-2 Diabetes, and Alzheimer's Disease. Front Aging Neurosci. 2017; 9:263. PMID: 28871222; PMCID: PMC5566559.
    Citations: 25     
  28. Fischer DB, Fried PJ, Ruffini G, Ripolles O, Salvador R, Banus J, Ketchabaw WT, Santarnecchi E, Pascual-Leone A, Fox MD. Multifocal tDCS targeting the resting state motor network increases cortical excitability beyond traditional tDCS targeting unilateral motor cortex. Neuroimage. 2017 08 15; 157:34-44. PMID: 28572060.
    Citations: 47     Fields:    Translation:Humans
  29. Hatchard T, Mioduszewski O, Fall C, Byron-Alhassan A, Fried P, Smith AM. Neural impact of low-level alcohol use on response inhibition: An fMRI investigation in young adults. Behav Brain Res. 2017 06 30; 329:12-19. PMID: 28435127.
    Citations: 5     Fields:    Translation:Humans
  30. Fried PJ, Schilberg L, Brem AK, Saxena S, Wong B, Cypess AM, Horton ES, Pascual-Leone A. Humans with Type-2 Diabetes Show Abnormal Long-Term Potentiation-Like Cortical Plasticity Associated with Verbal Learning Deficits. J Alzheimers Dis. 2017; 55(1):89-100. PMID: 27636847; PMCID: PMC5193103.
    Citations: 23     Fields:    Translation:Humans
  31. Gonsalvez I, Baror R, Fried P, Santarnecchi E, Pascual-Leone A. Therapeutic Noninvasive Brain Stimulation in Alzheimer's Disease. Curr Alzheimer Res. 2017; 14(4):362-376. PMID: 27697061.
    Citations: 22     Fields:    Translation:Humans
  32. Chang WH, Fried PJ, Saxena S, Jannati A, Gomes-Osman J, Kim YH, Pascual-Leone A. Optimal number of pulses as outcome measures of neuronavigated transcranial magnetic stimulation. Clin Neurophysiol. 2016 08; 127(8):2892-2897. PMID: 27156431.
    Citations: 41     Fields:    Translation:Humans
  33. Wang Y, Hao Y, Zhou J, Fried PJ, Wang X, Zhang J, Fang J, Pascual-Leone A, Manor B. Direct current stimulation over the human sensorimotor cortex modulates the brain's hemodynamic response to tactile stimulation. Eur J Neurosci. 2015 Aug; 42(3):1933-40. PMID: 25989209; PMCID: PMC4523467.
    Citations: 12     Fields:    Translation:Humans
  34. Mir-Moghtadaei A, Caballero R, Fried P, Fox MD, Lee K, Giacobbe P, Daskalakis ZJ, Blumberger DM, Downar J. Concordance Between BeamF3 and MRI-neuronavigated Target Sites for Repetitive Transcranial Magnetic Stimulation of the Left Dorsolateral Prefrontal Cortex. Brain Stimul. 2015 Sep-Oct; 8(5):965-73. PMID: 26115776.
    Citations: 51     Fields:    Translation:Humans
  35. Fried PJ, Rushmore RJ, Moss MB, Valero-Cabré A, Pascual-Leone A. Causal evidence supporting functional dissociation of verbal and spatial working memory in the human dorsolateral prefrontal cortex. Eur J Neurosci. 2014 Jun; 39(11):1973-81. PMID: 24713032.
    Citations: 18     Fields:    Translation:Humans
  36. Brem AK, Fried PJ, Horvath JC, Robertson EM, Pascual-Leone A. Is neuroenhancement by noninvasive brain stimulation a net zero-sum proposition? Neuroimage. 2014 Jan 15; 85 Pt 3:1058-68. PMID: 23880500.
    Citations: 39     Fields:    Translation:Humans
  37. Fried PJ, Elkin-Frankston S, Rushmore RJ, Hilgetag CC, Valero-Cabre A. Characterization of visual percepts evoked by noninvasive stimulation of the human posterior parietal cortex. PLoS One. 2011; 6(11):e27204. PMID: 22087266.
    Citations: 13     Fields:    Translation:Humans
  38. Elkin-Frankston S, Fried P, Rushmore RJ, Valero-Cabré A. From qualia to quantia: a system to document and quantify phosphene percepts elicited by non-invasive neurostimulation of the human occipital cortex. J Neurosci Methods. 2011 Jun 15; 198(2):149-57. PMID: 21419796.
    Citations: 3     Fields:    Translation:HumansCells
  39. Elkin-Frankston S, Fried PJ, Pascual-Leone A, Rushmore RJ, Valero-Cabr A. A novel approach for documenting phosphenes induced by transcranial magnetic stimulation. J Vis Exp. 2010 Apr 01; (38). PMID: 20360672.
    Citations: 9     Fields:    Translation:Humans
  40. Smith A, Fried P, Hogan M, Cameron I. The effects of prenatal and current marijuana exposure on response inhibition: a functional magnetic resonance imaging study. Brain Cogn. 2004 Mar; 54(2):147-9. PMID: 15025044.
    Citations: 2     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.