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Gad A Getz, Ph.D.
Title
Professor of Pathology
Institution
Massachusetts General Hospital
Department
Pathology
Address
Massachusetts General Hospital
Cancer Center, 7-220
149 13th Street
Charlestown MA 02129
Phone
617/724-7014
Fax
617/726-5637
vCard
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research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
U24HG012090
(ARDLIE, KRISTIN)
Sep 22, 2021 - Jun 30, 2026
NIH
Developmental GTEx Laboratory, Data Analysis and Coordination Center
Role: Co-Principal Investigator
U24CA264024
(GETZ, GAD A)
Sep 20, 2021 - Aug 31, 2026
NIH
Comprehensive analysis of point mutations in cancer
Role: Principal Investigator
U41HG009494
(ARDLIE, KRISTIN)
Aug 15, 2017 - May 31, 2022
NIH
A portal and integrative collaborative analysis platform for GTEx
Role: Co-Principal Investigator
U24CA210999
(GETZ, GAD A)
Sep 20, 2016 - Aug 31, 2021
NIH
Global Infrastructure for Collaborative High-throughput Cancer Genomics Analysis
Role: Principal Investigator
U24CA210979
(MANI, DENKANIKOTA R)
Sep 15, 2016 - Aug 31, 2021
NIH
Integrated high throughput proteogenomic data analysis center for CPTAC
Role: Principal Investigator
P01CA206978
(WU, CATHERINE JU-YING)
Sep 1, 2016 - Aug 31, 2026
NIH
Comprehensive dissection of the CLL genome & phenome to improve patient outcomes
Role: Co-Principal Investigator
P01CA163222
(FISHER, DAVID E)
Mar 12, 2013 - Jun 30, 2024
NIH
Targetable epigenetic and transcriptional mechanisms in melanoma that shape the microenvironment
Role: Co-Principal Investigator
U24CA143845
(GETZ, GAD)
Sep 29, 2009 - Dec 31, 2016
NIH
The Cancer Genome Atlas Data Analysis Center
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
El-Khoury H
, Lee DJ,
Alberge JB
, Redd R, Cea-Curry CJ, Perry J, Barr H, Murphy C, Sakrikar D, Barnidge D, Bustoros M, Leblebjian H, Cowan A, Davis MI, Amstutz J, Boehner CJ,
Lightbody ED
, Sklavenitis-Pistofidis R, Perkins MC, Harding S,
Mo CC
, Kapoor P, Mikhael J, Borrello IM, Fonseca R,
Weiss ST
, Karlson E,
Trippa L
,
Rebbeck TR
,
Getz G
,
Marinac CR
,
Ghobrial IM
. Prevalence of monoclonal gammopathies and clinical outcomes in a high-risk US population screened by mass spectrometry: a multicentre cohort study. Lancet Haematol. 2022 Mar 25.
PMID:
35344689
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Freeman SS,
Sade-Feldman M
, Kim J, Stewart C, Gonye ALK,
Ravi A
, Arniella MB, Gushterova I, LaSalle TJ, Blaum EM, Yizhak K, Frederick DT, Sharova T, Leshchiner I, Elagina L, Spiro OG, Livitz D, Rosebrock D, Aguet F, Carrot-Zhang J, Ha G, Lin Z,
Chen JH
, Barzily-Rokni M, Hammond MR, Vitzthum von Eckstaedt HC, Blackmon SM, Jiao YJ, Gabriel S, Lawrence DP,
Duncan LM
,
Stemmer-Rachamimov AO
, Wargo JA,
Flaherty KT
, Sullivan RJ,
Boland GM
,
Meyerson M
,
Getz G
,
Hacohen N
. Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma. Cell Rep Med. 2022 Feb 15; 3(2):100500.
PMID:
35243413
.
Citations:
Fields:
Med
Medicine (General)
Dutta AK
,
Alberge JB
, Sklavenitis-Pistofidis R,
Lightbody ED
,
Getz G
,
Ghobrial IM
. Single-cell profiling of tumour evolution in multiple myeloma - opportunities for precision medicine. Nat Rev Clin Oncol. 2022 Apr; 19(4):223-236.
PMID:
35017721
.
Citations:
1
Fields:
Neo
Neoplasms
Ito T
, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, Dutta S,
Pal D
, Paolella BR, Rothberg MV, Root DE, Johannessen CM, Parida L,
Getz G
, Vazquez F, Doench JG, Zamanighomi M,
Sellers WR
. Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Nat Genet. 2021 12; 53(12):1664-1672.
PMID:
34857952
.
Citations:
2
Fields:
Gen
Genetics
Translation:
Humans
Cells
Penter L
, Gohil SH, Lareau C, Ludwig LS,
Parry EM
, Huang T, Li S, Zhang W, Livitz D, Leshchiner I, Parida L,
Getz G
, Rassenti LZ, Kipps TJ,
Brown JR
,
Davids MS
,
Neuberg DS
, Livak KJ,
Sankaran VG
,
Wu CJ
. Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History. Cancer Discov. 2021 Dec 01; 11(12):3048-3063.
PMID:
34112698
.
Citations:
4
Fields:
Neo
Neoplasms
Ouspenskaia T, Law T, Clauser KR, Klaeger S, Sarkizova S, Aguet F, Li B, Christian E, Knisbacher BA, Le PM, Hartigan CR, Keshishian H, Apffel A,
Oliveira G
, Zhang W, Chen S, Chow YT, Ji Z, Jungreis I, Shukla SA, Justesen S, Bachireddy P, Kellis M,
Getz G
,
Hacohen N
, Keskin DB, Carr SA,
Wu CJ
, Regev A. Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer. Nat Biotechnol. 2022 Feb; 40(2):209-217.
PMID:
34663921
.
Citations:
9
Fields:
Bio
Biotechnology
Tewari AK
, Cheung ATM, Crowdis J, Conway JR, Camp SY, Wankowicz SA, Livitz DG, Park J, Lis RT, Bosma-Moody A, He MX,
AlDubayan SH
, Zhang Z, McKay RR, Leshchiner I, Brown M,
Balk SP
,
Getz G
,
Taplin ME
,
Van Allen EM
. Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer. Cell Rep. 2021 09 07; 36(10):109665.
PMID:
34496240
.
Citations:
1
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Coates JT
,
Sun S
, Leshchiner I, Thimmiah N, Martin EE, McLoughlin D, Danysh BP, Slowik K, Jacobs RA, Rhrissorrakrai K, Utro F, Levovitz C, Denault E, Walmsley CS, Kambadakone A,
Stone JR
,
Isakoff SJ
, Parida L,
Juric D
,
Getz G
,
Bardia A
,
Ellisen LW
. Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021 10; 11(10):2436-2445.
PMID:
34404686
.
Citations:
2
Fields:
Neo
Neoplasms
Satpathy S, Krug K, Jean Beltran PM, Savage SR, Petralia F, Kumar-Sinha C, Dou Y, Reva B, Kane MH, Avanessian SC, Vasaikar SV, Krek A, Lei JT, Jaehnig EJ, Omelchenko T, Geffen Y, Bergstrom EJ, Stathias V, Christianson KE, Heiman DI, Cieslik MP, Cao S, Song X, Ji J, Liu W, Li K, Wen B, Li Y, Gümüs ZH, Selvan ME, Soundararajan R, Visal TH, Raso MG, Parra ER, Babur Ö, Vats P, Anand S, Schraink T, Cornwell M, Rodrigues FM, Zhu H, Mo CK, Zhang Y, da Veiga Leprevost F, Huang C, Chinnaiyan AM, Wyczalkowski MA, Omenn GS, Newton CJ, Schurer S, Ruggles KV, Fenyö D, Jewell SD, Thiagarajan M, Mesri M, Rodriguez H, Mani SA, Udeshi ND,
Getz G
, Suh J, Li QK, Hostetter G, Paik PK, Dhanasekaran SM, Govindan R, Ding L, Robles AI, Clauser KR, Nesvizhskii AI, Wang P, Carr SA, Zhang B, Mani DR,
Gillette MA
. A proteogenomic portrait of lung squamous cell carcinoma. Cell. 2021 08 05; 184(16):4348-4371.e40.
PMID:
34358469
.
Citations:
6
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Beauchamp EM
, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A, Wong W, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M,
Niroula A
, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Desai P, Cho MH, Johnson AD, Loos R,
MacArthur DG
, Lek M,
Neuberg DS
, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C,
Getz G
, Bradley RK, Jaiswal S,
Ebert BL
. ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021 09; 2(5):500-517.
PMID:
34568833
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Gutierrez C, Al'Khafaji AM, Brenner E, Johnson KE, Gohil SH, Lin Z, Knisbacher BA, Durrett RE, Li S,
Parvin S
, Biran A, Zhang W, Rassenti L, Kipps TJ, Livak KJ,
Neuberg D
,
Letai A
,
Getz G
,
Wu CJ
, Brock A. Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. Nat Cancer. 2021 Jul; 2(7):758-772.
PMID:
34939038
.
Citations:
4
Murali I
, Kasar S,
Naeem A
,
Tyekucheva S
,
Khalsa JK
, Thrash EM,
Itchaki G
, Livitz D, Leshchiner I, Dong S, Fernandes SM,
Getz G
, Johnson A,
Brown JR
. Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia. Blood. 2021 07 08; 138(1):44-56.
PMID:
33684943
.
Citations:
6
Fields:
Hem
Hematology
Translation:
Humans
Cells
Sklavenitis-Pistofidis R, Haradhvala NJ,
Getz G
,
Ghobrial IM
. Inflammatory stromal cells in the myeloma microenvironment. Nat Immunol. 2021 06; 22(6):677-678.
PMID:
34017125
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Mani DR, Maynard M, Kothadia R, Krug K, Christianson KE, Heiman D, Clauser KR, Birger C,
Getz G
, Carr SA. PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis. Nat Methods. 2021 06; 18(6):580-582.
PMID:
34040252
.
Citations:
4
Fields:
Cli
Clinical Laboratory Techniques
Graubert A, Aguet F,
Ravi A
, Ardlie KG,
Getz G
. RNA-SeQC 2: Efficient RNA-seq quality control and quantification for large cohorts. Bioinformatics. 2021 Mar 02.
PMID:
33677499
.
Citations:
2
Fields:
Com
Computational Biology
Sklavenitis-Pistofidis R,
Getz G
,
Ghobrial I
. Single-cell RNA sequencing: one step closer to the clinic. Nat Med. 2021 03; 27(3):375-376.
PMID:
33664491
.
Citations:
1
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L,
Rheinbay E
, Liu EM, Trieu T, Haan D, Yau C, Hinoue T, Liu Y, Shapira O, Kumar K, Mungall KL, Zhang H,
Lee JJ
, Berger A, Gao GF, Zhitomirsky B, Liang WW,
Zhou M
, Moorthi S, Berger AH, Collisson EA, Zody MC, Ding L,
Cherniack AD
,
Getz G
, Elemento O, Benz CC, Stuart J, Zenklusen JC,
Beroukhim R
, Chang JC, Campbell JD, Hayes DN, Yang L, Laird PW, Weinstein JN,
Kwiatkowski DJ
, Tsao MS, Travis WD, Khurana E, Berman BP, Hoadley KA, Robine N,
Meyerson M
, Govindan R, Imielinski M. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Rep. 2021 02 02; 34(5):108707.
PMID:
33535033
.
Citations:
2
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Krug K, Jaehnig EJ, Satpathy S, Blumenberg L, Karpova A, Anurag M, Miles G, Mertins P, Geffen Y, Tang LC, Heiman DI, Cao S, Maruvka YE, Lei JT, Huang C, Kothadia RB, Colaprico A, Birger C, Wang J, Dou Y, Wen B, Shi Z, Liao Y, Wiznerowicz M, Wyczalkowski MA, Chen XS, Kennedy JJ, Paulovich AG, Thiagarajan M, Kinsinger CR, Hiltke T, Boja ES, Mesri M, Robles AI, Rodriguez H, Westbrook TF, Ding L,
Getz G
, Clauser KR, Fenyö D, Ruggles KV, Zhang B, Mani DR, Carr SA, Ellis MJ,
Gillette MA
. Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. 2020 11 25; 183(5):1436-1456.e31.
PMID:
33212010
.
Citations:
44
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Hong X
, Roh W, Sullivan RJ, Wong KHK,
Wittner BS
, Guo H, Dubash TD,
Sade-Feldman M
, Wesley B,
Horwitz E
,
Boland GM
, Marvin DL, Bonesteel T, Lu C, Aguet F,
Burr R
, Freeman SS, Parida L, Calhoun K, Jewett MK, Nieman LT,
Hacohen N
, Näär AM, Ting DT, Toner M,
Stott SL
,
Getz G
,
Maheswaran S
, Haber DA. The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis. Cancer Discov. 2021 03; 11(3):678-695.
PMID:
33203734
.
Citations:
19
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Giannikou K
, Zhu Z, Kim J,
Winden KD
, Tyburczy ME, Marron D, Parker JS, Hebert Z, Bongaarts A, Taing L,
Long HW
, Pisano WV,
Alexandrescu S
, Godlewski B, Nellist M, Kotulska K, Jozwiak S, Roszkowski M, Mandera M,
Thiele EA
,
Lidov H
,
Getz G
, Devinsky O,
Lawrence MS
,
Ligon KL
, Ellison DW,
Sahin M
, Aronica E,
Meredith DM
,
Kwiatkowski DJ
. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile. Mod Pathol. 2021 02; 34(2):264-279.
PMID:
33051600
.
Citations:
Fields:
Pat
Pathology
Translation:
Humans
Cells
Bachireddy P, Ennis C, Nguyen VN, Gohil SH,
Clement K
, Shukla SA, Forman J, Barkas N, Freeman S, Bavli N, Elagina L, Leshchiner I, Mohammad AW, Mathewson ND, Keskin DB, Rassenti LZ, Kipps TJ,
Brown JR
,
Getz G
,
Ho VT
, Gnirke A,
Neuberg D
,
Soiffer RJ
,
Ritz J
, Alyea EP,
Kharchenko PV
,
Wu CJ
. Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect. Sci Transl Med. 2020 09 16; 12(561).
PMID:
32938797
.
Citations:
3
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Bellmunt J, Kim J, Reardon B, Perera-Bel J, Orsola A, Rodriguez-Vida A, Wankowicz SA, Bowden M,
Barletta JA
, Morote J, de Torres I, Juanpere N, Lloreta-Trull J, Hernandez S,
Mouw KW
,
Taplin ME
,
Cejas P
,
Long HW
,
Van Allen EM
,
Getz G
,
Kwiatkowski DJ
. Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer. Cancer Res. 2020 10 15; 80(20):4476-4486.
PMID:
32868381
.
Citations:
9
Fields:
Neo
Neoplasms
Translation:
Humans
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D,
Getz G
,
Boland GM
, Chen F,
Buenrostro JD
,
Hacohen N
,
Wu CJ
,
Aryee MJ
, Regev A,
Sankaran VG
. Massively parallel single-cell mitochondrial DNA genotyping and chromatin profiling. Nat Biotechnol. 2021 04; 39(4):451-461.
PMID:
32788668
.
Citations:
31
Fields:
Bio
Biotechnology
Translation:
Humans
Cells
Gillette MA
, Satpathy S, Cao S, Dhanasekaran SM, Vasaikar SV, Krug K, Petralia F, Li Y, Liang WW, Reva B, Krek A, Ji J, Song X, Liu W, Hong R, Yao L, Blumenberg L, Savage SR, Wendl MC, Wen B, Li K, Tang LC, MacMullan MA, Avanessian SC, Kane MH, Newton CJ, Cornwell M, Kothadia RB, Ma W, Yoo S, Mannan R, Vats P, Kumar-Sinha C, Kawaler EA, Omelchenko T, Colaprico A, Geffen Y, Maruvka YE, da Veiga Leprevost F, Wiznerowicz M, Gümüs ZH, Veluswamy RR, Hostetter G, Heiman DI, Wyczalkowski MA, Hiltke T, Mesri M, Kinsinger CR, Boja ES, Omenn GS, Chinnaiyan AM, Rodriguez H, Li QK, Jewell SD, Thiagarajan M,
Getz G
, Zhang B, Fenyö D, Ruggles KV, Cieslik MP, Robles AI, Clauser KR, Govindan R, Wang P, Nesvizhskii AI, Ding L, Mani DR, Carr SA. Proteogenomic Characterization Reveals Therapeutic Vulnerabilities in Lung Adenocarcinoma. Cell. 2020 07 09; 182(1):200-225.e35.
PMID:
32649874
.
Citations:
87
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Vidula N
, Dubash T,
Lawrence MS
,
Simoneau A
,
Niemierko A
, Blouch E, Nagy B, Roh W, Chirn B, Reeves BA, Malvarosa G,
Lennerz J
,
Isakoff SJ
,
Juric D
,
Micalizzi D
,
Wander S
,
Spring L
,
Moy B
, Shannon K, Younger J, Lanman R, Toner M,
Iafrate AJ
,
Getz G
,
Zou L
,
Ellisen LW
,
Maheswaran S
, Haber DA,
Bardia A
. Identification of Somatically Acquired BRCA1/2 Mutations by cfDNA Analysis in Patients with Metastatic Breast Cancer. Clin Cancer Res. 2020 09 15; 26(18):4852-4862.
PMID:
32571788
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Mouhieddine TH
,
Sperling AS
, Redd R, Park J, Leventhal M,
Gibson CJ
, Manier S,
Nassar AH
, Capelletti M, Huynh D, Bustoros M, Sklavenitis-Pistofidis R,
Tahri S
, Hornburg K, Dumke H, Itani MM, Boehner CJ, Liu CJ,
AlDubayan SH
, Reardon B,
Van Allen EM
, Keats JJ, Stewart C, Mehr S, Auclair D, Schlossman RL,
Munshi NC
,
Anderson KC
, Steensma DP,
Laubach JP
,
Richardson PG
,
Ritz J
,
Ebert BL
,
Soiffer RJ
,
Trippa L
,
Getz G
,
Neuberg DS
,
Ghobrial IM
. Clonal hematopoiesis is associated with adverse outcomes in multiple myeloma patients undergoing transplant. Nat Commun. 2020 06 12; 11(1):2996.
PMID:
32533060
.
Citations:
18
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Bustoros M, Sklavenitis-Pistofidis R, Park J, Redd R, Zhitomirsky B, Dunford AJ, Salem K,
Tai YT
, Anand S,
Mouhieddine TH
, Chavda SJ, Boehner C, Elagina L, Neuse CJ, Cha J,
Rahmat M
, Taylor-Weiner A,
Van Allen E
, Kumar S, Kastritis E, Leshchiner I,
Morgan EA
,
Laubach J
, Casneuf T,
Richardson P
,
Munshi NC
,
Anderson KC
,
Trippa L
, Aguet F, Stewart C, Dimopoulos MA, Yong K, Bergsagel PL, Manier S,
Getz G
,
Ghobrial IM
. Genomic Profiling of Smoldering Multiple Myeloma Identifies Patients at a High Risk of Disease Progression. J Clin Oncol. 2020 07 20; 38(21):2380-2389.
PMID:
32442065
.
Citations:
32
Fields:
Neo
Neoplasms
Translation:
Humans
Zavidij O, Haradhvala NJ,
Mouhieddine TH
, Sklavenitis-Pistofidis R,
Cai S
, Reidy M,
Rahmat M
, Flaifel A, Ferland B, Su NK,
Agius MP
, Park J, Manier S, Bustoros M, Huynh D, Capelletti M, Berrios B, Liu CJ, He MX, Braggio E, Fonseca R, Maruvka Y,
Guerriero JL
, Goldman M,
van Allen E
,
McCarroll SA
,
Azzi J
,
Getz G
,
Ghobrial IM
. Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020 05; 1(5):493-506.
PMID:
33409501
.
Citations:
45
Parsons HA
, Rhoades J, Reed SC, Gydush G, Ram P, Exman P, Xiong K, Lo CC, Li T, Fleharty M, Kirkner GJ, Rotem D,
Cohen O
, Yu F, Fitarelli-Kiehl M, Leong KW, Hughes ME, Rosenberg SM,
Collins LC
, Miller KD, Blumenstiel B,
Trippa L
, Cibulskis C,
Neuberg DS
, DeFelice M, Freeman SS, Lennon NJ,
Wagle N
, Ha G, Stover DG,
Choudhury AD
,
Getz G
,
Winer EP
,
Meyerson M
,
Lin NU
, Krop I, Love JC,
Makrigiorgos GM
,
Partridge AH
,
Mayer EL
,
Golub TR
, Adalsteinsson VA. Sensitive Detection of Minimal Residual Disease in Patients Treated for Early-Stage Breast Cancer. Clin Cancer Res. 2020 06 01; 26(11):2556-2564.
PMID:
32170028
.
Citations:
20
Fields:
Neo
Neoplasms
Translation:
Humans
Rheinbay E
, Nielsen MM, Abascal F,
Wala JA
, Shapira O, Tiao G, Hornshøj H, Hess JM, Juul RI, Lin Z, Feuerbach L, Sabarinathan R, Madsen T, Kim J, Mularoni L, Shuai S, Lanzós A, Herrmann C, Maruvka YE, Shen C, Amin SB,
Bandopadhayay P
, Bertl J, Boroevich KA, Busanovich J, Carlevaro-Fita J, Chakravarty D, Chan CWY, Craft D, Dhingra P, Diamanti K, Fonseca NA, Gonzalez-Perez A, Guo Q, Hamilton MP, Haradhvala NJ, Hong C, Isaev K, Johnson TA, Juul M, Kahles A, Kahraman A, Kim Y, Komorowski J, Kumar K, Kumar S, Lee D, Lehmann KV, Li Y, Liu EM, Lochovsky L, Park K, Pich O, Roberts ND, Saksena G, Schumacher SE, Sidiropoulos N, Sieverling L, Sinnott-Armstrong N, Stewart C, Tamborero D, Tubio JMC, Umer HM, Uusküla-Reimand L, Wadelius C, Wadi L, Yao X, Zhang CZ, Zhang J, Haber JE, Hobolth A, Imielinski M, Kellis M,
Lawrence MS
, von Mering C, Nakagawa H, Raphael BJ, Rubin MA,
Sander C
, Stein LD, Stuart JM, Tsunoda T, Wheeler DA, Johnson R, Reimand J, Gerstein M, Khurana E, Campbell PJ, López-Bigas N, Weischenfeldt J,
Beroukhim R
, Martincorena I, Pedersen JS,
Getz G
. Analyses of non-coding somatic drivers in 2,658 cancer whole genomes. Nature. 2020 02; 578(7793):102-111.
PMID:
32025015
.
Citations:
123
Fields:
Sci
Science
Translation:
Humans
Chapuy B, Stewart C, Dunford AJ, Kim J, Wienand K, Kamburov A,
Griffin GK
, Chen PH, Lako A, Redd RA, Cote CM, Ducar MD, Thorner AR,
Rodig SJ
,
Getz G
,
Shipp MA
. Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade. Blood. 2019 12 26; 134(26):2369-2382.
PMID:
31697821
.
Citations:
20
Fields:
Hem
Hematology
Translation:
Humans
Wienand K, Chapuy B, Stewart C, Dunford AJ, Wu D, Kim J, Kamburov A, Wood TR, Cader FZ, Ducar MD, Thorner AR, Nag A, Heubeck AT, Buonopane MJ, Redd RA, Bojarczuk K,
Lawton LN
,
Armand P
,
Rodig SJ
, Fromm JR,
Getz G
,
Shipp MA
. Genomic analyses of flow-sorted Hodgkin Reed-Sternberg cells reveal complementary mechanisms of immune evasion. Blood Adv. 2019 12 10; 3(23):4065-4080.
PMID:
31816062
.
Citations:
27
Fields:
Hem
Hematology
Translation:
Humans
Cells
Parikh AR
, Leshchiner I, Elagina L,
Goyal L
, Levovitz C, Siravegna G, Livitz D, Rhrissorrakrai K, Martin EE, Van Seventer EE, Hanna M, Slowik K, Utro F, Pinto CJ, Wong A, Danysh BP, de la Cruz FF, Fetter IJ, Nadres B, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Clark JW
, Giantonio B,
Murphy JE
,
Nipp RD
, Roeland E,
Ryan DP
,
Weekes CD
, Kwak EL, Faris JE,
Wo JY
, Aguet F, Dey-Guha I, Hazar-Rethinam M,
Dias-Santagata D
, Ting DT, Zhu AX,
Hong TS
,
Golub TR
,
Iafrate AJ
, Adalsteinsson VA, Bardelli A, Parida L,
Juric D
,
Getz G
,
Corcoran RB
. Author Correction: Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. Nat Med. 2019 Dec; 25(12):1949.
PMID:
31745334
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Taylor-Weiner A, Aguet F, Haradhvala NJ, Gosai S, Anand S, Kim J, Ardlie K,
Van Allen EM
,
Getz G
. Scaling computational genomics to millions of individuals with GPUs. Genome Biol. 2019 11 01; 20(1):228.
PMID:
31675989
.
Citations:
14
Fields:
Gen
Genetics
Guièze R, Liu VM, Rosebrock D, Jourdain AA, Hernández-Sánchez M, Martinez Zurita A, Sun J,
Ten Hacken E
, Baranowski K, Thompson PA, Heo JM, Cartun Z, Aygün O,
Iorgulescu JB
, Zhang W, Notarangelo G, Livitz D, Li S,
Davids MS
, Biran A, Fernandes SM,
Brown JR
, Lako A, Ciantra ZB, Lawlor MA, Keskin DB, Udeshi ND, Wierda WG, Livak KJ,
Letai AG
,
Neuberg D
,
Harper JW
, Carr SA, Piccioni F,
Ott CJ
, Leshchiner I, Johannessen CM, Doench J,
Mootha VK
,
Getz G
,
Wu CJ
. Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies. Cancer Cell. 2019 10 14; 36(4):369-384.e13.
PMID:
31543463
.
Citations:
73
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Hess JM,
Bernards A
, Kim J, Miller M, Taylor-Weiner A, Haradhvala NJ,
Lawrence MS
,
Getz G
. Passenger Hotspot Mutations in Cancer. Cancer Cell. 2019 09 16; 36(3):288-301.e14.
PMID:
31526759
.
Citations:
24
Fields:
Neo
Neoplasms
Translation:
Humans
Parikh AR
, Leshchiner I, Elagina L,
Goyal L
, Levovitz C, Siravegna G, Livitz D, Rhrissorrakrai K, Martin EE, Van Seventer EE, Hanna M, Slowik K, Utro F, Pinto CJ, Wong A, Danysh BP, de la Cruz FF, Fetter IJ, Nadres B, Shahzade HA, Allen JN,
Blaszkowsky LS
,
Clark JW
, Giantonio B,
Murphy JE
,
Nipp RD
, Roeland E,
Ryan DP
,
Weekes CD
, Kwak EL, Faris JE,
Wo JY
, Aguet F, Dey-Guha I, Hazar-Rethinam M,
Dias-Santagata D
, Ting DT, Zhu AX,
Hong TS
,
Golub TR
,
Iafrate AJ
, Adalsteinsson VA, Bardelli A, Parida L,
Juric D
,
Getz G
,
Corcoran RB
. Liquid versus tissue biopsy for detecting acquired resistance and tumor heterogeneity in gastrointestinal cancers. Nat Med. 2019 09; 25(9):1415-1421.
PMID:
31501609
.
Citations:
104
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID,
Wheeler MA
, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J,
Reardon DA
, Zhang H,
Robson SC
,
Getz G
,
Weiner HL
,
Quintana FJ
. Author Correction: Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39. Nat Neurosci. 2019 Sep; 22(9):1533.
PMID:
31197266
.
Citations:
2
Fields:
Neu
Neurology
Nissim S
, Leshchiner I,
Mancias JD
, Greenblatt MB, Maertens O,
Cassa CA
, Rosenfeld JA, Cox AG, Hedgepeth J, Wucherpfennig JI, Kim AJ, Henderson JE, Gonyo P, Brandt A, Lorimer E, Unger B, Prokop JW, Heidel JR, Wang XX,
Ukaegbu CI
, Jennings BC,
Paulo JA
, Gableske S, Fierke CA,
Getz G
,
Sunyaev SR
, Wade Harper J,
Cichowski K
, Kimmelman AC, Houvras Y,
Syngal S
, Williams C,
Goessling W
. Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer. Nat Genet. 2019 09; 51(9):1308-1314.
PMID:
31406347
.
Citations:
19
Fields:
Gen
Genetics
Translation:
Humans
Animals
Cells
Yizhak K, Aguet F, Kim J, Hess JM, Kübler K, Grimsby J, Frazer R, Zhang H, Haradhvala NJ, Rosebrock D, Livitz D, Li X, Arich-Landkof E, Shoresh N, Stewart C, Segrè AV, Branton PA, Polak P, Ardlie KG,
Getz G
. RNA sequence analysis reveals macroscopic somatic clonal expansion across normal tissues. Science. 2019 Jun 07; 364(6444).
PMID:
31171663
.
Citations:
133
Fields:
Sci
Science
Translation:
Humans
Cells
Amin-Mansour A,
George S
, Sioletic S,
Carter SL
, Rosenberg M, Taylor-Weiner A, Stewart C, Chevalier A, Seepo S, Tracy A,
Getz G
, Hornick JL,
Nucci MR
,
Quade B
,
Demetri GD
,
Raut CP
, Garraway LA,
Van Allen EM
,
Wagner AJ
. Genomic Evolutionary Patterns of Leiomyosarcoma and Liposarcoma. Clin Cancer Res. 2019 08 15; 25(16):5135-5142.
PMID:
31164371
.
Citations:
6
Fields:
Neo
Neoplasms
Translation:
Humans
Gruber M, Bozic I, Leshchiner I, Livitz D, Stevenson K, Rassenti L, Rosebrock D, Taylor-Weiner A, Olive O, Goyetche R, Fernandes SM, Sun J, Stewart C, Wong A, Cibulskis C, Zhang W, Reiter JG, Gerold JM, Gribben JG, Rai KR, Keating MJ,
Brown JR
,
Neuberg D
, Kipps TJ, Nowak MA,
Getz G
,
Wu CJ
. Growth dynamics in naturally progressing chronic lymphocytic leukaemia. Nature. 2019 06; 570(7762):474-479.
PMID:
31142838
.
Citations:
26
Fields:
Sci
Science
Translation:
Humans
Cells
Goyal L
,
Shi L
, Liu LY,
Fece de la Cruz F
,
Lennerz JK
,
Raghavan S
, Leschiner I, Elagina L, Siravegna G, Ng RWS, Vu P, Patra KC, Saha SK,
Uppot RN
,
Arellano R
, Reyes S, Sagara T, Otsuki S, Nadres B, Shahzade HA, Dey-Guha I, Fetter IJ, Baiev I, Van Seventer EE,
Murphy JE
,
Ferrone CR
,
Tanabe KK
,
Deshpande V
, Harding JJ, Yaeger R, Kelley RK, Bardelli A,
Iafrate AJ
,
Hahn WC
, Benes CH, Ting DT, Hirai H,
Getz G
,
Juric D
, Zhu AX,
Corcoran RB
, Bardeesy N. TAS-120 Overcomes Resistance to ATP-Competitive FGFR Inhibitors in Patients with FGFR2 Fusion-Positive Intrahepatic Cholangiocarcinoma. Cancer Discov. 2019 08; 9(8):1064-1079.
PMID:
31109923
.
Citations:
69
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ghandi M, Huang FW, Jané-Valbuena J, Kryukov GV, Lo CC, McDonald ER, Barretina J, Gelfand ET, Bielski CM, Li H, Hu K, Andreev-Drakhlin AY, Kim J, Hess JM, Haas BJ, Aguet F, Weir BA, Rothberg MV, Paolella BR,
Lawrence MS
, Akbani R, Lu Y, Tiv HL, Gokhale PC, de Weck A, Mansour AA, Oh C, Shih J, Hadi K, Rosen Y, Bistline J, Venkatesan K, Reddy A, Sonkin D, Liu M, Lehar J, Korn JM, Porter DA, Jones MD, Golji J, Caponigro G, Taylor JE, Dunning CM, Creech AL, Warren AC, McFarland JM, Zamanighomi M, Kauffmann A, Stransky N, Imielinski M, Maruvka YE,
Cherniack AD
, Tsherniak A, Vazquez F, Jaffe JD,
Lane AA
,
Weinstock DM
, Johannessen CM, Morrissey MP, Stegmeier F, Schlegel R,
Hahn WC
,
Getz G
, Mills GB, Boehm JS,
Golub TR
, Garraway LA,
Sellers WR
. Next-generation characterization of the Cancer Cell Line Encyclopedia. Nature. 2019 05; 569(7757):503-508.
PMID:
31068700
.
Citations:
638
Fields:
Sci
Science
Translation:
Humans
Cells
Chan EM
, Shibue T, McFarland JM, Gaeta B, Ghandi M, Dumont N, Gonzalez A, McPartlan JS, Li T, Zhang Y, Bin Liu J, Lazaro JB, Gu P, Piett CG, Apffel A, Ali SO, Deasy R, Keskula P, Ng RWS, Roberts EA, Reznichenko E, Leung L, Alimova M, Schenone M, Islam M, Maruvka YE, Liu Y, Roper J,
Raghavan S
,
Giannakis M
, Tseng YY,
Nagel ZD
,
D'Andrea A
, Root DE, Boehm JS,
Getz G
, Chang S,
Golub TR
, Tsherniak A, Vazquez F, Bass AJ. WRN helicase is a synthetic lethal target in microsatellite unstable cancers. Nature. 2019 04; 568(7753):551-556.
PMID:
30971823
.
Citations:
87
Fields:
Sci
Science
Translation:
Humans
Cells
Takenaka MC, Gabriely G, Rothhammer V, Mascanfroni ID,
Wheeler MA
, Chao CC, Gutiérrez-Vázquez C, Kenison J, Tjon EC, Barroso A, Vandeventer T, de Lima KA, Rothweiler S, Mayo L, Ghannam S, Zandee S, Healy L, Sherr D, Farez MF, Prat A, Antel J,
Reardon DA
, Zhang H,
Robson SC
,
Getz G
,
Weiner HL
,
Quintana FJ
. Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39. Nat Neurosci. 2019 05; 22(5):729-740.
PMID:
30962630
.
Citations:
128
Fields:
Neu
Neurology
Translation:
Humans
Animals
Cells
Maruvka YE, Haradhvala NJ,
Getz G
. Analyzing Frequently Mutated Genes and the Association With Tumor Mutation Load. JAMA Oncol. 2019 04 01; 5(4):577.
PMID:
30844029
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Kangeyan D, Dunford A, Iyer S, Stewart C, Hanna M,
Getz G
,
Aryee MJ
. A (fire)cloud-based DNA methylation data preprocessing and quality control platform. BMC Bioinformatics. 2019 Mar 29; 20(1):160.
PMID:
30922215
.
Citations:
4
Fields:
Com
Computational Biology
Translation:
Humans
Cells
Kim J,
Kwiatkowski D
, McConkey DJ, Meeks JJ, Freeman SS, Bellmunt J,
Getz G
, Lerner SP. The Cancer Genome Atlas Expression Subtypes Stratify Response to Checkpoint Inhibition in Advanced Urothelial Cancer and Identify a Subset of Patients with High Survival Probability. Eur Urol. 2019 06; 75(6):961-964.
PMID:
30851984
.
Citations:
39
Fields:
Uro
Urology
Translation:
Humans
Cells
Artomov M
, Joseph V, Tiao G, Thomas T, Schrader K, Klein RJ, Kiezun A, Gupta N, Margolin L, Stratigos AJ, Kim I, Shannon K,
Ellisen LW
, Haber D,
Getz G
,
Tsao H
, Lipkin SM,
Altshuler D
, Offit K,
Daly MJ
. Case-control analysis identifies shared properties of rare germline variation in cancer predisposing genes. Eur J Hum Genet. 2019 05; 27(5):824-828.
PMID:
30718883
.
Citations:
2
Fields:
Gen
Genetics
Translation:
Humans
Yin S
, Gambe RG, Sun J, Martinez AZ, Cartun ZJ, Regis FFD, Wan Y, Fan J, Brooks AN, Herman SEM,
Ten Hacken E
, Taylor-Weiner A, Rassenti LZ, Ghia EM, Kipps TJ, Obeng EA, Cibulskis CL,
Neuberg D
,
Campagna DR
,
Fleming MD
,
Ebert BL
, Wiestner A, Leshchiner I,
DeCaprio JA
,
Getz G
,
Reed R
,
Carrasco RD
,
Wu CJ
, Wang L. A Murine Model of Chronic Lymphocytic Leukemia Based on B Cell-Restricted Expression of Sf3b1 Mutation and Atm Deletion. Cancer Cell. 2019 02 11; 35(2):283-296.e5.
PMID:
30712845
.
Citations:
21
Fields:
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Barretina J, Caponigro G, Stransky N, Venkatesan K, Margolin AA, Kim S, Wilson CJ, Lehár J, Kryukov GV, Sonkin D, Reddy A, Liu M, Murray L, Berger MF, Monahan JE, Morais P, Meltzer J, Korejwa A, Jané-Valbuena J, Mapa FA, Thibault J, Bric-Furlong E, Raman P, Shipway A, Engels IH, Cheng J, Yu GK, Yu J, Aspesi P, de Silva M, Jagtap K, Jones MD, Wang L, Hatton C, Palescandolo E, Gupta S, Mahan S, Sougnez C, Onofrio RC, Liefeld T,
MacConaill L
, Winckler W, Reich M, Li N, Mesirov JP, Gabriel SB,
Getz G
, Ardlie K, Chan V, Myer VE, Weber BL, Porter J, Warmuth M, Finan P, Harris JL,
Meyerson M
,
Golub TR
, Morrissey MP,
Sellers WR
, Schlegel R, Garraway LA. Addendum: The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity. Nature. 2019 01; 565(7738):E5-E6.
PMID:
30559381
.
Citations:
22
Fields:
Sci
Science
Keskin DB,
Anandappa AJ
, Sun J, Tirosh I, Mathewson ND, Li S,
Oliveira G
, Giobbie-Hurder A, Felt K, Gjini E, Shukla SA, Hu Z, Li L, Le PM, Allesøe RL, Richman AR, Kowalczyk MS, Abdelrahman S, Geduldig JE, Charbonneau S, Pelton K,
Iorgulescu JB
, Elagina L, Zhang W, Olive O, McCluskey C, Olsen LR, Stevens J,
Lane WJ
, Salazar AM, Daley H,
Wen PY
,
Chiocca EA
, Harden M, Lennon NJ, Gabriel S,
Getz G
,
Lander ES
, Regev A,
Ritz J
,
Neuberg D
,
Rodig SJ
,
Ligon KL
, Suvà ML,
Wucherpfennig KW
,
Hacohen N
,
Fritsch EF
, Livak KJ,
Ott PA
,
Wu CJ
,
Reardon DA
. Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial. Nature. 2019 01; 565(7738):234-239.
PMID:
30568305
.
Citations:
356
Fields:
Sci
Science
Translation:
Humans
Cells
CT
Clinical Trials
Brody Y, Kimmerling RJ, Maruvka YE, Benjamin D, Elacqua JJ, Haradhvala NJ, Kim J,
Mouw KW
, Frangaj K, Koren A,
Getz G
, Manalis SR, Blainey PC. Quantification of somatic mutation flow across individual cell division events by lineage sequencing. Genome Res. 2018 12; 28(12):1901-1918.
PMID:
30459213
.
Citations:
9
Fields:
Gen
Genetics
Translation:
Humans
Cells
Choudhury AD
, Werner L, Francini E, Wei XX, Ha G, Freeman SS, Rhoades J, Reed SC, Gydush G, Rotem D, Lo C,
Taplin ME
, Harshman LC, Zhang Z, O'Connor EP, Stover DG,
Parsons HA
,
Getz G
,
Meyerson M
, Love JC,
Hahn WC
, Adalsteinsson VA. Tumor fraction in cell-free DNA as a biomarker in prostate cancer. JCI Insight. 2018 11 02; 3(21).
PMID:
30385733
.
Citations:
25
Fields:
Med
Medicine (General)
Translation:
Humans
CT
Clinical Trials
Sade-Feldman M
, Yizhak K, Bjorgaard SL, Ray JP, de Boer CG,
Jenkins RW
, Lieb DJ,
Chen JH
, Frederick DT, Barzily-Rokni M, Freeman SS, Reuben A,
Hoover PJ
,
Villani AC
, Ivanova E, Portell A, Lizotte PH, Aref AR, Eliane JP, Hammond MR, Vitzthum H, Blackmon SM, Li B, Gopalakrishnan V, Reddy SM, Cooper ZA,
Paweletz CP
,
Barbie DA
,
Stemmer-Rachamimov A
,
Flaherty KT
, Wargo JA,
Boland GM
, Sullivan RJ,
Getz G
,
Hacohen N
. Defining T Cell States Associated with Response to Checkpoint Immunotherapy in Melanoma. Cell. 2018 11 01; 175(4):998-1013.e20.
PMID:
30388456
.
Citations:
380
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Stewart C, Leshchiner I, Hess J,
Getz G
. Comment on "DNA damage is a pervasive cause of sequencing errors, directly confounding variant identification". Science. 2018 09 28; 361(6409).
PMID:
30262473
.
Citations:
Fields:
Sci
Science
Translation:
Humans
Udler MS
, Kim J, von Grotthuss M, Bonàs-Guarch S,
Cole JB
, Chiou J, Boehnke M, Laakso M, Atzmon G, Glaser B, Mercader JM, Gaulton K,
Flannick J
,
Getz G
,
Florez JC
. Type 2 diabetes genetic loci informed by multi-trait associations point to disease mechanisms and subtypes: A soft clustering analysis. PLoS Med. 2018 09; 15(9):e1002654.
PMID:
30240442
.
Citations:
106
Fields:
Med
Medicine (General)
Translation:
Humans
Giacomelli AO, Yang X, Lintner RE, McFarland JM, Duby M, Kim J,
Howard TP
, Takeda DY, Ly SH, Kim E, Gannon HS, Hurhula B, Sharpe T, Goodale A, Fritchman B, Steelman S, Vazquez F, Tsherniak A,
Aguirre AJ
, Doench JG, Piccioni F, Roberts CWM,
Meyerson M
,
Getz G
, Johannessen CM, Root DE,
Hahn WC
. Mutational processes shape the landscape of TP53 mutations in human cancer. Nat Genet. 2018 10; 50(10):1381-1387.
PMID:
30224644
.
Citations:
104
Fields:
Gen
Genetics
Translation:
Humans
Cells
Miao D, Margolis CA, Vokes NI,
Liu D
, Taylor-Weiner A, Wankowicz SM, Adeegbe D, Keliher D, Schilling B, Tracy A, Manos M, Chau NG,
Hanna GJ
, Polak P,
Rodig SJ
,
Signoretti S
,
Sholl LM
, Engelman JA,
Getz G
, Jänne PA,
Haddad RI
,
Choueiri TK
,
Barbie DA
,
Haq R
,
Awad MM
, Schadendorf D,
Hodi FS
, Bellmunt J, Wong KK, Hammerman P,
Van Allen EM
. Genomic correlates of response to immune checkpoint blockade in microsatellite-stable solid tumors. Nat Genet. 2018 09; 50(9):1271-1281.
PMID:
30150660
.
Citations:
150
Fields:
Gen
Genetics
Translation:
Humans
Cells
Gopal RK
, Kübler K,
Calvo SE
, Polak P, Livitz D, Rosebrock D,
Sadow PM
, Campbell B, Donovan SE, Amin S, Gigliotti BJ, Grabarek Z, Hess JM, Stewart C, Braunstein LZ, Arndt PF, Mordecai S,
Shih AR
, Chaves F, Zhan T,
Lubitz CC
, Kim J,
Iafrate AJ
,
Wirth L
,
Parangi S
, Leshchiner I,
Daniels GH
,
Mootha VK
,
Dias-Santagata D
,
Getz G
, McFadden DG. Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma. Cancer Cell. 2018 08 13; 34(2):242-255.e5.
PMID:
30107175
.
Citations:
52
Fields:
Neo
Neoplasms
Translation:
Humans
Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, O'Rourke R, Garrity A, Tubelli AA,
Bandopadhayay P
, Tsherniak A, Vazquez F, Wong B, Birger C, Ghandi M, Thorner AR, Bittker JA,
Meyerson M
,
Getz G
,
Beroukhim R
,
Golub TR
. Genetic and transcriptional evolution alters cancer cell line drug response. Nature. 2018 08; 560(7718):325-330.
PMID:
30089904
.
Citations:
233
Fields:
Sci
Science
Translation:
Humans
Cells
Chapuy B, Stewart C, Dunford AJ, Kim J, Kamburov A, Redd RA, Lawrence MS, Roemer MGM, Li AJ, Ziepert M, Staiger AM, Wala JA, Ducar MD, Leshchiner I, Rheinbay E, Taylor-Weiner A, Coughlin CA, Hess JM, Pedamallu CS, Livitz D, Rosebrock D, Rosenberg M, Tracy AA, Horn H, van Hummelen P, Feldman AL, Link BK, Novak AJ, Cerhan JR, Habermann TM, Siebert R, Rosenwald A, Thorner AR,
Meyerson ML
,
Golub TR
,
Beroukhim R
, Wulf GG, Ott G,
Rodig SJ
, Monti S,
Neuberg DS
, Loeffler M, Pfreundschuh M, Trümper L,
Getz G
,
Shipp MA
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