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Gad A Getz, Ph.D.
Title
Professor of Pathology
Institution
Massachusetts General Hospital
Department
Pathology
Address
Massachusetts General Hospital
Cancer Center, 7-220
149 13th Street
Charlestown MA 02129
Phone
617/724-7014
Fax
617/726-5637
vCard
Download vCard
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login for email
)
research activities and funding
|
selected publications
|
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
U24HG012090
(ARDLIE, KRISTIN)
Sep 22, 2021 - Jun 30, 2026
NIH
Developmental GTEx Laboratory, Data Analysis and Coordination Center
Role: Co-Principal Investigator
U24CA264024
(GETZ, GAD A)
Sep 20, 2021 - Aug 31, 2026
NIH
Comprehensive analysis of point mutations in cancer
Role: Principal Investigator
U41HG009494
(ARDLIE, KRISTIN)
Aug 15, 2017 - May 31, 2022
NIH
A portal and integrative collaborative analysis platform for GTEx
Role: Co-Principal Investigator
U24CA210999
(GETZ, GAD A)
Sep 20, 2016 - Aug 31, 2021
NIH
Global Infrastructure for Collaborative High-throughput Cancer Genomics Analysis
Role: Principal Investigator
U24CA210979
(MANI, DENKANIKOTA R)
Sep 15, 2016 - Aug 31, 2021
NIH
Integrated high throughput proteogenomic data analysis center for CPTAC
Role: Principal Investigator
P01CA206978
(WU, CATHERINE JU-YING)
Sep 1, 2016 - Aug 31, 2026
NIH
Comprehensive dissection of the CLL genome & phenome to improve patient outcomes
Role: Co-Principal Investigator
P01CA163222
(FISHER, DAVID E)
Mar 12, 2013 - Jun 30, 2024
NIH
Targetable epigenetic and transcriptional mechanisms in melanoma that shape the microenvironment
Role: Co-Principal Investigator
U24CA143845
(GETZ, GAD)
Sep 29, 2009 - Dec 31, 2016
NIH
The Cancer Genome Atlas Data Analysis Center
Role: Co-Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Parry EM
, Leshchiner I, Guièze R, Johnson C, Tausch E, Parikh SA, Lemvigh C, Broséus J, Hergalant S, Messer C, Utro F, Levovitz C, Rhrissorrakrai K, Li L, Rosebrock D, Yin S, Deng S, Slowik K, Jacobs R, Huang T, Li S, Fell G, Redd R, Lin Z, Knisbacher BA, Livitz D, Schneider C, Ruthen N, Elagina L, Taylor-Weiner A, Persaud B, Martinez A, Fernandes SM, Purroy N, Anandappa AJ, Ma J, Hess J, Rassenti LZ, Kipps TJ, Jain N, Wierda W, Cymbalista F, Feugier P, Kay NE, Livak KJ, Danysh BP, Stewart C,
Neuberg D
,
Davids MS
,
Brown JR
, Parida L, Stilgenbauer S,
Getz G
,
Wu CJ
. Evolutionary history of transformation from chronic lymphocytic leukemia to Richter syndrome. Nat Med. 2023 Jan 09.
PMID:
36624313
.
Citations:
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Dutta AK
,
Alberge JB
,
Lightbody ED
, Boehner CJ, Dunford A, Sklavenitis-Pistofidis R, Mouhieddine TH, Cowan AN, Su NK, Horowitz EM, Barr H, Hevenor L, Beckwith JB, Perry J, Cao A, Lin Z, Kuhr FK, Del Mastro RG,
Nadeem O
, Greipp PT, Stewart C, Auclair D,
Getz G
,
Ghobrial IM
. MinimuMM-seq: Genome sequencing of circulating tumor cells for minimally invasive molecular characterization of multiple myeloma pathology. Cancer Discov. 2022 Dec 07.
PMID:
36477267
.
Citations:
Fields:
Neo
Neoplasms
Ten Hacken E
, Sewastianik T, Yin S, Brunsting Hoffmann G, Gruber M,
Clement K
,
Penter L
, Redd RA, Ruthen N, Hergalant S, Sholokhova A, Fell G,
Parry EM
, Broseus J, Guieze R,
Lucas F
, Hernandez-Sanchez M, Baranowski K, Southard J, Joyal H, Billington L, Regis FFD, Witten E, Uduman M, Knisbacher BA, Li S, Lyu H, Vaisitti T, Deaglio S, Inghirami G, Feugier P, Stilgenbauer S, Tausch E,
Davids MS
,
Getz G
, Livak KJ, Bozic I,
Neuberg DS
,
Carrasco RD
,
Wu CJ
. In vivo modeling of CLL transformation to Richter's syndrome reveals convergent evolutionary paths and therapeutic vulnerabilities. Blood Cancer Discov. 2022 12 05.
PMID:
36468984
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Tsuji J, Li T,
Grinshpun A
, Coorens T, Russo D, Anderson L, Rees R, Nardone A, Patterson C, Lennon NJ, Cibulskis C, Leshchiner I,
Tayob N
,
Tolaney SM
,
Tung N
, McDonnell DP, Krop IE, Winer EP, Stewart C,
Getz G
,
Jeselsohn R
. Clinical Efficacy and Whole-Exome Sequencing of Liquid Biopsies in a Phase IB/II Study of Bazedoxifene and Palbociclib in Advanced Hormone Receptor-Positive Breast Cancer. Clin Cancer Res. 2022 12 01; 28(23):5066-5078.
PMID:
36215125
; PMCID:
PMC9722539
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
CT
Clinical Trials
Boiarsky R, Haradhvala NJ,
Alberge JB
, Sklavenitis-Pistofidis R, Mouhieddine TH, Zavidij O, Shih MC, Firer D, Miller M,
El-Khoury H
, Anand SK, Aguet F, Sontag D,
Ghobrial IM
,
Getz G
. Single cell characterization of myeloma and its precursor conditions reveals transcriptional signatures of early tumorigenesis. Nat Commun. 2022 11 17; 13(1):7040.
PMID:
36396631
; PMCID:
PMC9672303
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Cells
Sklavenitis-Pistofidis R,
Aranha MP
, Redd RA, Baginska J, Haradhvala NJ, Hallisey M,
Dutta AK
, Savell A, Varmeh S, Heilpern-Mallory D, Ujwary S, Zavidij O, Aguet F, Su NK,
Lightbody ED
, Bustoros M,
Tahri S
, Mouhieddine TH, Wu T, Flechon L, Anand S,
Rosenblatt JM
, Zonder J, Vredenburgh JJ, Boruchov A, Bhutani M, Usmani SZ, Matous J,
Yee AJ
, Jakubowiak A,
Laubach J
, Manier S,
Nadeem O
,
Richardson P
, Badros AZ, Mateos MV,
Trippa L
,
Getz G
,
Ghobrial IM
. Immune biomarkers of response to immunotherapy in patients with high-risk smoldering myeloma. Cancer Cell. 2022 11 14; 40(11):1358-1373.e8.
PMID:
36379208
.
Citations:
1
Fields:
Neo
Neoplasms
Translation:
Humans
Roh W, Geffen Y, Cha H, Miller M, Anand S, Kim J, Heiman DI,
Gainor JF
, Laird PW,
Cherniack AD
, Ock CY, Lee SH,
Getz G
. High-Resolution Profiling of Lung Adenocarcinoma Identifies Expression Subtypes with Specific Biomarkers and Clinically Relevant Vulnerabilities. Cancer Res. 2022 11 02; 82(21):3917-3931.
PMID:
36040373
; PMCID:
PMC9718502
.
Citations:
Fields:
Neo
Neoplasms
Translation:
Humans
Naeem A
, Utro F, Wang Q, Cha J, Vihinen M, Martindale SP, Zhou Y, Ren Y,
Tyekucheva S
,
Kim AS
, Fernandes SM, Saksena G, Rhrissorrakrai K, Levovitz C, Danysh BP, Slowik K, Jacobs RA,
Davids MS
,
Lederer JA
, Zain R, Smith CIE, Leshchiner I, Parida L,
Getz G
,
Brown JR
. Pirtobrutinib Targets BTK C481S in Ibrutinib-Resistant CLL but Second-Site BTK Mutations Lead to Resistance. Blood Adv. 2022 Oct 26.
PMID:
36287227
.
Citations:
Fields:
Hem
Hematology
Gao GF, Oh C, Saksena G, Deng D, Westlake LC, Hill BA, Reich M, Schumacher SE, Berger AC,
Carter SL
,
Cherniack AD
,
Meyerson M
, Tabak B,
Beroukhim R
,
Getz G
. Tangent normalization for somatic copy-number inference in cancer genome analysis. Bioinformatics. 2022 10 14; 38(20):4677-4686.
PMID:
36040167
; PMCID:
PMC9563697
.
Citations:
Fields:
Com
Computational Biology
Translation:
Humans
Haradhvala NJ,
Leick MB
, Maurer K, Gohil SH, Larson RC, Yao N,
Gallagher KME
, Katsis K,
Frigault MJ
, Southard J, Li S, Kann MC, Silva H,
Jan M
, Rhrissorrakrai K, Utro F, Levovitz C, Jacobs RA, Slowik K, Danysh BP, Livak KJ, Parida L,
Ferry J
,
Jacobson C
,
Wu CJ
,
Getz G
,
Maus MV
. Distinct cellular dynamics associated with response to CAR-T therapy for refractory B cell lymphoma. Nat Med. 2022 09; 28(9):1848-1859.
PMID:
36097221
; PMCID:
PMC9509487
.
Citations:
1
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Tsai JW
,
Cejas P
, Wang DK, Patel S, Wu DW, Arounleut P, Wei X, Zhou N, Syamala S, Dubois FPB, Crane A, Pelton K, Vogelzang J, Sousa C, Baguette A, Chen X,
Condurat AL
,
Dixon-Clarke SE
, Zhou KN, Lu SD, Gonzalez EM, Chacon MS, Digiacomo JJ, Kumbhani R, Novikov D, Hunter J, Tsoli M, Ziegler DS, Dirksen U, Jager N, Balasubramanian GP, Kramm CM, Nathrath M, Bielack S, Baker SJ, Zhang J, McFarland JM,
Getz G
, Aguet F, Jabado N, Witt O, Pfister SM,
Ligon KL
,
Hovestadt V
, Kleinman CL,
Long H
, Jones DTW,
Bandopadhayay P
, Phoenix TN. FOXR2 Is an Epigenetically Regulated Pan-Cancer Oncogene That Activates ETS Transcriptional Circuits. Cancer Res. 2022 09 02; 82(17):2980-3001.
PMID:
35802025
; PMCID:
PMC9437574
.
Citations:
Fields:
Neo
Neoplasms
Knisbacher BA, Lin Z,
Hahn CK
, Nadeu F, Duran-Ferrer M, Stevenson KE, Tausch E, Delgado J, Barbera-Mourelle A, Taylor-Weiner A, Bousquets-Muñoz P, Diaz-Navarro A, Dunford A, Anand S, Kretzmer H, Gutierrez-Abril J, López-Tamargo S, Fernandes SM, Sun C, Sivina M, Rassenti LZ, Schneider C, Li S, Parida L,
Meissner A
, Aguet F, Burger JA, Wiestner A, Kipps TJ,
Brown JR
, Hallek M, Stewart C,
Neuberg DS
, Martín-Subero JI, Puente XS, Stilgenbauer S,
Wu CJ
, Campo E,
Getz G
. Molecular map of chronic lymphocytic leukemia and its impact on outcome. Nat Genet. 2022 11; 54(11):1664-1674.
PMID:
35927489
.
Citations:
Fields:
Gen
Genetics
Translation:
Humans
Cells
Ricciuti B
,
Wang X
, Alessi JV, Rizvi H,
Mahadevan NR
,
Li YY
, Polio A, Lindsay J,
Umeton R
, Sinha R, Vokes NI, Recondo G, Lamberti G, Lawrence M,
Vaz VR
, Leonardi GC, Plodkowski AJ, Gupta H,
Cherniack AD
, Tolstorukov MY, Sharma B, Felt KD,
Gainor JF
,
Ravi A
,
Getz G
, Schalper KA, Henick B, Forde P, Anagnostou V, Jänne PA,
Van Allen EM
, Nishino M,
Sholl LM
, Christiani DC, Lin X,
Rodig SJ
, Hellmann MD,
Awad MM
. Association of High Tumor Mutation Burden in Non-Small Cell Lung Cancers With Increased Immune Infiltration and Improved Clinical Outcomes of PD-L1 Blockade Across PD-L1 Expression Levels. JAMA Oncol. 2022 08 01; 8(8):1160-1168.
PMID:
35708671
; PMCID:
PMC9204620
.
Citations:
Fields:
Neo
Neoplasms
Sklavenitis-Pistofidis R,
Getz G
,
Ghobrial I
, Papaioannou M. Multiple Myeloma With Amplification of Chr1q: Therapeutic Opportunity and Challenges. Front Oncol. 2022; 12:961421.
PMID:
35912171
; PMCID:
PMC9331166
.
Citations:
Bustoros M, Anand S, Sklavenitis-Pistofidis R, Redd R, Boyle EM, Zhitomirsky B, Dunford AJ,
Tai YT
, Chavda SJ, Boehner C, Neuse CJ,
Rahmat M
,
Dutta A
, Casneuf T, Verona R, Kastritis E,
Trippa L
, Stewart C, Walker BA, Davies FE, Dimopoulos MA, Bergsagel PL, Yong K, Morgan GJ, Aguet F,
Getz G
,
Ghobrial IM
. Genetic subtypes of smoldering multiple myeloma are associated with distinct pathogenic phenotypes and clinical outcomes. Nat Commun. 2022 06 15; 13(1):3449.
PMID:
35705541
; PMCID:
PMC9200804
.
Citations:
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Eraslan G, Drokhlyansky E, Anand S, Fiskin E,
Subramanian A
, Slyper M, Wang J, Van Wittenberghe N, Rouhana JM, Waldman J, Ashenberg O, Lek M, Dionne D,
Win TS
, Cuoco MS, Kuksenko O, Tsankov AM, Branton PA, Marshall JL,
Greka A
,
Getz G
, Segrè AV, Aguet F, Rozenblatt-Rosen O, Ardlie KG, Regev A. Single-nucleus cross-tissue molecular reference maps toward understanding disease gene function. Science. 2022 05 13; 376(6594):eabl4290.
PMID:
35549429
; PMCID:
PMC9383269
.
Citations:
4
Fields:
Sci
Science
Translation:
Humans
Cells
Larson RC, Kann MC,
Bailey SR
, Haradhvala NJ, Llopis PM, Bouffard AA, Scarfó I,
Leick MB
,
Grauwet K
, Berger TR, Stewart K,
Anekal PV
,
Jan M
, Joung J, Schmidts A, Ouspenskaia T, Law T, Regev A,
Getz G
,
Maus MV
. CAR T cell killing requires the IFN?R pathway in solid but not liquid tumours. Nature. 2022 04; 604(7906):563-570.
PMID:
35418687
.
Citations:
2
Fields:
Sci
Science
Translation:
Humans
Cells
El-Khoury H
, Lee DJ,
Alberge JB
, Redd R, Cea-Curry CJ, Perry J, Barr H, Murphy C, Sakrikar D, Barnidge D, Bustoros M, Leblebjian H, Cowan A, Davis MI, Amstutz J, Boehner CJ,
Lightbody ED
, Sklavenitis-Pistofidis R, Perkins MC, Harding S,
Mo CC
, Kapoor P, Mikhael J, Borrello IM, Fonseca R,
Weiss ST
, Karlson E,
Trippa L
,
Rebbeck TR
,
Getz G
,
Marinac CR
,
Ghobrial IM
. Prevalence of monoclonal gammopathies and clinical outcomes in a high-risk US population screened by mass spectrometry: a multicentre cohort study. Lancet Haematol. 2022 May; 9(5):e340-e349.
PMID:
35344689
; PMCID:
PMC9067621
.
Citations:
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Freeman SS,
Sade-Feldman M
, Kim J, Stewart C, Gonye ALK,
Ravi A
, Arniella MB, Gushterova I, LaSalle TJ, Blaum EM, Yizhak K, Frederick DT, Sharova T, Leshchiner I, Elagina L, Spiro OG, Livitz D, Rosebrock D, Aguet F, Carrot-Zhang J, Ha G, Lin Z,
Chen JH
, Barzily-Rokni M, Hammond MR, Vitzthum von Eckstaedt HC, Blackmon SM, Jiao YJ, Gabriel S, Lawrence DP,
Duncan LM
,
Stemmer-Rachamimov AO
, Wargo JA,
Flaherty KT
, Sullivan RJ,
Boland GM
,
Meyerson M
,
Getz G
,
Hacohen N
. Combined tumor and immune signals from genomes or transcriptomes predict outcomes of checkpoint inhibition in melanoma. Cell Rep Med. 2022 02 15; 3(2):100500.
PMID:
35243413
; PMCID:
PMC8861826
.
Citations:
1
Fields:
Med
Medicine (General)
Translation:
Humans
Cells
Dutta AK
,
Alberge JB
, Sklavenitis-Pistofidis R,
Lightbody ED
,
Getz G
,
Ghobrial IM
. Single-cell profiling of tumour evolution in multiple myeloma - opportunities for precision medicine. Nat Rev Clin Oncol. 2022 04; 19(4):223-236.
PMID:
35017721
.
Citations:
3
Fields:
Neo
Neoplasms
Translation:
Humans
Ito T, Young MJ, Li R, Jain S, Wernitznig A, Krill-Burger JM, Lemke CT, Monducci D, Rodriguez DJ, Chang L, Dutta S,
Pal D
, Paolella BR, Rothberg MV, Root DE, Johannessen CM, Parida L,
Getz G
, Vazquez F, Doench JG, Zamanighomi M,
Sellers WR
. Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers. Nat Genet. 2021 12; 53(12):1664-1672.
PMID:
34857952
.
Citations:
4
Fields:
Gen
Genetics
Translation:
Humans
Cells
Penter L
, Gohil SH, Lareau C, Ludwig LS,
Parry EM
, Huang T, Li S, Zhang W, Livitz D, Leshchiner I, Parida L,
Getz G
, Rassenti LZ, Kipps TJ,
Brown JR
,
Davids MS
,
Neuberg DS
, Livak KJ,
Sankaran VG
,
Wu CJ
. Longitudinal Single-Cell Dynamics of Chromatin Accessibility and Mitochondrial Mutations in Chronic Lymphocytic Leukemia Mirror Disease History. Cancer Discov. 2021 12 01; 11(12):3048-3063.
PMID:
34112698
; PMCID:
PMC8660953
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Ouspenskaia T, Law T, Clauser KR, Klaeger S, Sarkizova S, Aguet F, Li B, Christian E, Knisbacher BA, Le PM, Hartigan CR, Keshishian H, Apffel A,
Oliveira G
, Zhang W, Chen S, Chow YT, Ji Z, Jungreis I, Shukla SA, Justesen S, Bachireddy P, Kellis M,
Getz G
,
Hacohen N
,
Keskin DB
, Carr SA,
Wu CJ
, Regev A. Unannotated proteins expand the MHC-I-restricted immunopeptidome in cancer. Nat Biotechnol. 2022 02; 40(2):209-217.
PMID:
34663921
.
Citations:
11
Fields:
Bio
Biotechnology
Translation:
Humans
Tewari AK
, Cheung ATM, Crowdis J, Conway JR, Camp SY, Wankowicz SA, Livitz DG, Park J, Lis RT, Bosma-Moody A, He MX,
AlDubayan SH
, Zhang Z, McKay RR, Leshchiner I, Brown M,
Balk SP
,
Getz G
,
Taplin ME
,
Van Allen EM
. Molecular features of exceptional response to neoadjuvant anti-androgen therapy in high-risk localized prostate cancer. Cell Rep. 2021 09 07; 36(10):109665.
PMID:
34496240
.
Citations:
2
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Coates JT
,
Sun S
, Leshchiner I, Thimmiah N, Martin EE, McLoughlin D, Danysh BP, Slowik K, Jacobs RA, Rhrissorrakrai K, Utro F, Levovitz C, Denault E,
Walmsley CS
, Kambadakone A,
Stone JR
,
Isakoff SJ
, Parida L,
Juric D
,
Getz G
,
Bardia A
,
Ellisen LW
. Parallel Genomic Alterations of Antigen and Payload Targets Mediate Polyclonal Acquired Clinical Resistance to Sacituzumab Govitecan in Triple-Negative Breast Cancer. Cancer Discov. 2021 10; 11(10):2436-2445.
PMID:
34404686
; PMCID:
PMC8495771
.
Citations:
4
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Satpathy S, Krug K, Jean Beltran PM, Savage SR, Petralia F, Kumar-Sinha C, Dou Y, Reva B, Kane MH, Avanessian SC, Vasaikar SV, Krek A, Lei JT, Jaehnig EJ, Omelchenko T, Geffen Y, Bergstrom EJ, Stathias V, Christianson KE, Heiman DI, Cieslik MP, Cao S, Song X, Ji J, Liu W, Li K, Wen B, Li Y, Gümüs ZH, Selvan ME, Soundararajan R, Visal TH, Raso MG, Parra ER, Babur Ö, Vats P, Anand S, Schraink T, Cornwell M, Rodrigues FM, Zhu H, Mo CK, Zhang Y, da Veiga Leprevost F, Huang C, Chinnaiyan AM, Wyczalkowski MA, Omenn GS, Newton CJ, Schurer S, Ruggles KV, Fenyö D, Jewell SD, Thiagarajan M, Mesri M, Rodriguez H, Mani SA, Udeshi ND,
Getz G
, Suh J, Li QK, Hostetter G, Paik PK, Dhanasekaran SM, Govindan R, Ding L, Robles AI, Clauser KR, Nesvizhskii AI, Wang P, Carr SA, Zhang B, Mani DR,
Gillette MA
. A proteogenomic portrait of lung squamous cell carcinoma. Cell. 2021 08 05; 184(16):4348-4371.e40.
PMID:
34358469
; PMCID:
PMC8475722
.
Citations:
9
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Beauchamp EM, Leventhal M, Bernard E, Hoppe ER, Todisco G, Creignou M, Gallì A, Castellano CA, McConkey M, Tarun A,
Wong W
, Schenone M, Stanclift C, Tanenbaum B, Malolepsza E, Nilsson B, Bick AG, Weinstock JS, Miller M,
Niroula A
, Dunford A, Taylor-Weiner A, Wood T, Barbera A, Anand S, Psaty BM, Desai P, Cho MH, Johnson AD, Loos R, MacArthur DG, Lek M,
Neuberg DS
, Lage K, Carr SA, Hellstrom-Lindberg E, Malcovati L, Papaemmanuil E, Stewart C,
Getz G
, Bradley RK, Jaiswal S,
Ebert BL
. ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021 09; 2(5):500-517.
PMID:
34568833
; PMCID:
PMC8462124
.
Citations:
1
Fields:
Hem
Hematology
Neo
Neoplasms
Translation:
Humans
Animals
Cells
Gutierrez C
, Al'Khafaji AM, Brenner E, Johnson KE, Gohil SH, Lin Z, Knisbacher BA, Durrett RE, Li S,
Parvin S
, Biran A, Zhang W, Rassenti L, Kipps TJ, Livak KJ,
Neuberg D
,
Letai A
,
Getz G
,
Wu CJ
, Brock A. Multifunctional barcoding with ClonMapper enables high-resolution study of clonal dynamics during tumor evolution and treatment. Nat Cancer. 2021 07; 2(7):758-772.
PMID:
34939038
; PMCID:
PMC8691751
.
Citations:
7
Translation:
Humans
Cells
Murali I
, Kasar S,
Naeem A
,
Tyekucheva S
, Khalsa JK, Thrash EM, Itchaki G, Livitz D, Leshchiner I, Dong S, Fernandes SM,
Getz G
, Johnson A,
Brown JR
. Activation of the MAPK pathway mediates resistance to PI3K inhibitors in chronic lymphocytic leukemia. Blood. 2021 07 08; 138(1):44-56.
PMID:
33684943
; PMCID:
PMC8493976
.
Citations:
7
Fields:
Hem
Hematology
Translation:
Humans
Cells
Mani DR, Maynard M, Kothadia R, Krug K, Christianson KE, Heiman D, Clauser KR, Birger C,
Getz G
, Carr SA. PANOPLY: a cloud-based platform for automated and reproducible proteogenomic data analysis. Nat Methods. 2021 06; 18(6):580-582.
PMID:
34040252
; PMCID:
PMC8791030
.
Citations:
4
Fields:
Cli
Clinical Laboratory Techniques
Sklavenitis-Pistofidis R, Haradhvala NJ,
Getz G
,
Ghobrial IM
. Inflammatory stromal cells in the myeloma microenvironment. Nat Immunol. 2021 06; 22(6):677-678.
PMID:
34017125
.
Citations:
Fields:
All
Allergy and Immunology
Translation:
Humans
Cells
Graubert A, Aguet F,
Ravi A
, Ardlie KG,
Getz G
. RNA-SeQC 2: Efficient RNA-seq quality control and quantification for large cohorts. Bioinformatics. 2021 Mar 02.
PMID:
33677499
; PMCID:
PMC8479667
.
Citations:
3
Fields:
Com
Computational Biology
Sklavenitis-Pistofidis R,
Getz G
,
Ghobrial I
. Single-cell RNA sequencing: one step closer to the clinic. Nat Med. 2021 03; 27(3):375-376.
PMID:
33664491
.
Citations:
3
Fields:
Med
Medicine (General)
Mol
Molecular Biology
Translation:
Humans
Cells
Carrot-Zhang J, Yao X, Devarakonda S, Deshpande A, Damrauer JS, Silva TC, Wong CK, Choi HY, Felau I, Robertson AG, Castro MAA, Bao L,
Rheinbay E
, Liu EM, Trieu T, Haan D, Yau C, Hinoue T, Liu Y, Shapira O, Kumar K, Mungall KL, Zhang H,
Lee JJ
, Berger A, Gao GF, Zhitomirsky B, Liang WW,
Zhou M
, Moorthi S, Berger AH, Collisson EA, Zody MC, Ding L,
Cherniack AD
,
Getz G
, Elemento O, Benz CC, Stuart J, Zenklusen JC,
Beroukhim R
, Chang JC, Campbell JD, Hayes DN, Yang L, Laird PW, Weinstein JN,
Kwiatkowski DJ
, Tsao MS, Travis WD, Khurana E, Berman BP, Hoadley KA, Robine N,
Meyerson M
, Govindan R, Imielinski M. Whole-genome characterization of lung adenocarcinomas lacking the RTK/RAS/RAF pathway. Cell Rep. 2021 02 02; 34(5):108707.
PMID:
33535033
; PMCID:
PMC8009291
.
Citations:
3
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Krug K, Jaehnig EJ, Satpathy S, Blumenberg L, Karpova A, Anurag M, Miles G, Mertins P, Geffen Y, Tang LC, Heiman DI, Cao S, Maruvka YE, Lei JT, Huang C, Kothadia RB, Colaprico A, Birger C, Wang J, Dou Y, Wen B, Shi Z, Liao Y, Wiznerowicz M, Wyczalkowski MA, Chen XS, Kennedy JJ, Paulovich AG, Thiagarajan M, Kinsinger CR, Hiltke T, Boja ES, Mesri M, Robles AI, Rodriguez H, Westbrook TF, Ding L,
Getz G
, Clauser KR, Fenyö D, Ruggles KV, Zhang B, Mani DR, Carr SA, Ellis MJ,
Gillette MA
. Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy. Cell. 2020 11 25; 183(5):1436-1456.e31.
PMID:
33212010
.
Citations:
65
Fields:
Cel
Cell Biology
Translation:
Humans
Cells
Hong X, Roh W, Sullivan RJ, Wong KHK,
Wittner BS
, Guo H, Dubash TD,
Sade-Feldman M
, Wesley B,
Horwitz E
,
Boland GM
, Marvin DL, Bonesteel T, Lu C, Aguet F,
Burr R
, Freeman SS, Parida L, Calhoun K, Jewett MK, Nieman LT,
Hacohen N
, Näär AM, Ting DT, Toner M,
Stott SL
,
Getz G
,
Maheswaran S
, Haber DA. The Lipogenic Regulator SREBP2 Induces Transferrin in Circulating Melanoma Cells and Suppresses Ferroptosis. Cancer Discov. 2021 03; 11(3):678-695.
PMID:
33203734
; PMCID:
PMC7933049
.
Citations:
26
Fields:
Neo
Neoplasms
Translation:
Humans
Cells
Giannikou K, Zhu Z, Kim J,
Winden KD
, Tyburczy ME, Marron D, Parker JS, Hebert Z, Bongaarts A, Taing L,
Long HW
, Pisano WV,
Alexandrescu S
, Godlewski B, Nellist M, Kotulska K, Jozwiak S, Roszkowski M, Mandera M,
Thiele EA
,
Lidov H
,
Getz G
, Devinsky O,
Lawrence MS
,
Ligon KL
, Ellison DW,
Sahin M
, Aronica E,
Meredith DM
,
Kwiatkowski DJ
. Subependymal giant cell astrocytomas are characterized by mTORC1 hyperactivation, a very low somatic mutation rate, and a unique gene expression profile. Mod Pathol. 2021 02; 34(2):264-279.
PMID:
33051600
; PMCID:
PMC9361192
.
Citations:
2
Fields:
Pat
Pathology
Translation:
Humans
Cells
Bachireddy P, Ennis C, Nguyen VN, Gohil SH,
Clement K
, Shukla SA, Forman J, Barkas N, Freeman S, Bavli N, Elagina L, Leshchiner I, Mohammad AW, Mathewson ND,
Keskin DB
, Rassenti LZ, Kipps TJ,
Brown JR
,
Getz G
,
Ho VT
, Gnirke A,
Neuberg D
,
Soiffer RJ
,
Ritz J
, Alyea EP,
Kharchenko PV
,
Wu CJ
. Distinct evolutionary paths in chronic lymphocytic leukemia during resistance to the graft-versus-leukemia effect. Sci Transl Med. 2020 09 16; 12(561).
PMID:
32938797
; PMCID:
PMC7829680
.
Citations:
6
Fields:
Med
Medicine (General)
Sci
Science
Translation:
Humans
Bellmunt J, Kim J, Reardon B, Perera-Bel J, Orsola A, Rodriguez-Vida A, Wankowicz SA, Bowden M,
Barletta JA
, Morote J, de Torres I, Juanpere N, Lloreta-Trull J, Hernandez S,
Mouw KW
,
Taplin ME
,
Cejas P
,
Long HW
,
Van Allen EM
,
Getz G
,
Kwiatkowski DJ
. Genomic Predictors of Good Outcome, Recurrence, or Progression in High-Grade T1 Non-Muscle-Invasive Bladder Cancer. Cancer Res. 2020 10 15; 80(20):4476-4486.
PMID:
32868381
; PMCID:
PMC9361191
.
Citations:
15
Fields:
Neo
Neoplasms
Translation:
Humans
Lareau CA, Ludwig LS, Muus C, Gohil SH, Zhao T, Chiang Z, Pelka K, Verboon JM, Luo W, Christian E, Rosebrock D,
Getz G
,
Boland GM
, Chen F,