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Maria Carmela Speranza, Ph.D.

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Biography
2016
Award for the fifth Women in Medicine & Science Symposium
2015
Research excellence award

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Liu HJ, Lizotte PH, Du H, Speranza MC, Lam HC, Vaughan S, Alesi N, Wong KK, Freeman GJ, Sharpe AH, Henske EP. TSC2-deficient tumors have evidence of T cell exhaustion and respond to anti-PD-1/anti-CTLA-4 immunotherapy. JCI Insight. 2018 Apr 19; 3(8). PMID: 29669930.
    View in: PubMed
  2. Ricklefs FL, Alayo Q, Krenzlin H, Mahmoud AB, Speranza MC, Nakashima H, Hayes JL, Lee K, Balaj L, Passaro C, Rooj AK, Krasemann S, Carter BS, Chen CC, Steed T, Treiber J, Rodig S, Yang K, Nakano I, Lee H, Weissleder R, Breakefield XO, Godlewski J, Westphal M, Lamszus K, Freeman GJ, Bronisz A, Lawler SE, Chiocca EA. Immune evasion mediated by PD-L1 on glioblastoma-derived extracellular vesicles. Sci Adv. 2018 Mar; 4(3):eaar2766. PMID: 29532035.
    View in: PubMed
  3. Speranza MC, Passaro C, Ricklefs F, Kasai K, Klein SR, Nakashima H, Kaufmann JK, Ahmed AK, Nowicki MO, Obi P, Bronisz A, Aguilar-Cordova E, Aguilar LK, Guzik BW, Breakefield X, Weissleder R, Freeman GJ, Reardon DA, Wen PY, Chiocca EA, Lawler SE. Preclinical investigation of combined gene-mediated cytotoxic immunotherapy and immune checkpoint blockade in glioblastoma. Neuro Oncol. 2018 Jan 22; 20(2):225-235. PMID: 29016938.
    View in: PubMed
  4. Lawler SE, Speranza MC, Cho CF, Chiocca EA. Oncolytic Viruses in Cancer Treatment: A Review. JAMA Oncol. 2017 Jun 01; 3(6):841-849. PMID: 27441411.
    View in: PubMed
  5. Cho CF, Lee K, Speranza MC, Bononi FC, Viapiano MS, Luyt LG, Weissleder R, Chiocca EA, Lee H, Lawler SE. Design of a Microfluidic Chip for Magnetic-Activated Sorting of One-Bead-One-Compound Libraries. ACS Comb Sci. 2016 06 13; 18(6):271-8. PMID: 27124678.
    View in: PubMed
  6. Speranza MC, Nowicki MO, Behera P, Cho CF, Chiocca EA, Lawler SE. BKM-120 (Buparlisib): A Phosphatidyl-Inositol-3 Kinase Inhibitor with Anti-Invasive Properties in Glioblastoma. Sci Rep. 2016 Feb 05; 6:20189. PMID: 26846842; PMCID: PMC4742861.
  7. Speranza MC, Kasai K, Lawler SE. Preclinical Mouse Models for Analysis of the Therapeutic Potential of Engineered Oncolytic Herpes Viruses. ILAR J. 2016; 57(1):63-72. PMID: 27034396; PMCID: PMC4816123 [Available on 03/31/17].
  8. Nakashima H, Kaufmann JK, Wang PY, Nguyen T, Speranza MC, Kasai K, Okemoto K, Otsuki A, Nakano I, Fernandez S, Goins WF, Grandi P, Glorioso JC, Lawler S, Cripe TP, Chiocca EA. Histone deacetylase 6 inhibition enhances oncolytic viral replication in glioma. J Clin Invest. 2015 Nov 02; 125(11):4269-80. PMID: 26524593; PMCID: PMC4639993.
  9. De Rosa A, Pellegatta S, Rossi M, Tunici P, Magnoni L, Speranza MC, Malusa F, Miragliotta V, Mori E, Finocchiaro G, Bakker A. A radial glia gene marker, fatty acid binding protein 7 (FABP7), is involved in proliferation and invasion of glioblastoma cells. PLoS One. 2012; 7(12):e52113. PMID: 23284888; PMCID: PMC3528762.
  10. Frattini V, Pisati F, Speranza MC, Poliani PL, Frigé G, Cantini G, Kapetis D, Cominelli M, Rossi A, Finocchiaro G, Pellegatta S. FOXP3, a novel glioblastoma oncosuppressor, affects proliferation and migration. Oncotarget. 2012 Oct; 3(10):1146-57. PMID: 23888189; PMCID: PMC3717952.
  11. Speranza MC, Frattini V, Pisati F, Kapetis D, Porrati P, Eoli M, Pellegatta S, Finocchiaro G. NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma. Oncotarget. 2012 Jul; 3(7):723-34. PMID: 22869051; PMCID: PMC3443255.
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