Harvard Catalyst Profiles

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Natalia I. Vykhodtseva, Ph.D.

Co-Author

This page shows the publications co-authored by Natalia Vykhodtseva and Nathan McDannold.
Connection Strength

7.788
  1. McDannold N, Zhang Y, Vykhodtseva N. The Effects of Oxygen on Ultrasound-Induced Blood-Brain Barrier Disruption in Mice. Ultrasound Med Biol. 2017 02; 43(2):469-475.
    View in: PubMed
    Score: 0.770
  2. McDannold N, Livingstone M, Top CB, Sutton J, Todd N, Vykhodtseva N. Preclinical evaluation of a low-frequency transcranial MRI-guided focused ultrasound system in a primate model. Phys Med Biol. 2016 11 07; 61(21):7664-7687.
    View in: PubMed
    Score: 0.769
  3. McDannold N, Zhang Y, Vykhodtseva N. Nonthermal ablation in the rat brain using focused ultrasound and an ultrasound contrast agent: long-term effects. J Neurosurg. 2016 12; 125(6):1539-1548.
    View in: PubMed
    Score: 0.733
  4. McDannold N, Zhang YZ, Power C, Jolesz F, Vykhodtseva N. Nonthermal ablation with microbubble-enhanced focused ultrasound close to the optic tract without affecting nerve function. J Neurosurg. 2013 Nov; 119(5):1208-20.
    View in: PubMed
    Score: 0.620
  5. McDannold N, Zhang Y, Vykhodtseva N. Blood-brain barrier disruption and vascular damage induced by ultrasound bursts combined with microbubbles can be influenced by choice of anesthesia protocol. Ultrasound Med Biol. 2011 Aug; 37(8):1259-70.
    View in: PubMed
    Score: 0.530
  6. McDannold N, Zhang Y, Supko JG, Power C, Sun T, Vykhodtseva N, Golby AJ, Reardon DA. Blood-brain barrier disruption and delivery of irinotecan in a rat model using a clinical transcranial MRI-guided focused ultrasound system. Sci Rep. 2020 May 29; 10(1):8766.
    View in: PubMed
    Score: 0.247
  7. White PJ, Zhang YZ, Power C, Vykhodtseva N, McDannold N. Observed Effects of Whole-Brain Radiation Therapy on Focused Ultrasound Blood-Brain Barrier Disruption. Ultrasound Med Biol. 2020 Aug; 46(8):1998-2006.
    View in: PubMed
    Score: 0.247
  8. McDannold N, Zhang Y, Supko JG, Power C, Sun T, Peng C, Vykhodtseva N, Golby AJ, Reardon DA. Acoustic feedback enables safe and reliable carboplatin delivery across the blood-brain barrier with a clinical focused ultrasound system and improves survival in a rat glioma model. Theranostics. 2019; 9(21):6284-6299.
    View in: PubMed
    Score: 0.234
  9. Sun T, Zhang Y, Power C, Alexander PM, Sutton JT, Aryal M, Vykhodtseva N, Miller EL, McDannold NJ. Closed-loop control of targeted ultrasound drug delivery across the blood-brain/tumor barriers in a rat glioma model. Proc Natl Acad Sci U S A. 2017 11 28; 114(48):E10281-E10290.
    View in: PubMed
    Score: 0.207
  10. Park J, Aryal M, Vykhodtseva N, Zhang YZ, McDannold N. Evaluation of permeability, doxorubicin delivery, and drug retention in a rat brain tumor model after ultrasound-induced blood-tumor barrier disruption. J Control Release. 2017 03 28; 250:77-85.
    View in: PubMed
    Score: 0.192
  11. Kobus T, Vykhodtseva N, Pilatou M, Zhang Y, McDannold N. Safety Validation of Repeated Blood-Brain Barrier Disruption Using Focused Ultrasound. Ultrasound Med Biol. 2016 Feb; 42(2):481-92.
    View in: PubMed
    Score: 0.181
  12. McDannold N, Zhang Y, Power C, Arvanitis CD, Vykhodtseva N, Livingstone M. Targeted, noninvasive blockade of cortical neuronal activity. Sci Rep. 2015 Nov 06; 5:16253.
    View in: PubMed
    Score: 0.180
  13. Arvanitis CD, Vykhodtseva N, Jolesz F, Livingstone M, McDannold N. Cavitation-enhanced nonthermal ablation in deep brain targets: feasibility in a large animal model. J Neurosurg. 2016 May; 124(5):1450-9.
    View in: PubMed
    Score: 0.178
  14. Aryal M, Park J, Vykhodtseva N, Zhang YZ, McDannold N. Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model. Phys Med Biol. 2015 Mar 21; 60(6):2511-27.
    View in: PubMed
    Score: 0.172
  15. Aryal M, Vykhodtseva N, Zhang YZ, McDannold N. Multiple sessions of liposomal doxorubicin delivery via focused ultrasound mediated blood-brain barrier disruption: a safety study. J Control Release. 2015 Apr 28; 204:60-9.
    View in: PubMed
    Score: 0.172
  16. Aryal M, Vykhodtseva N, Zhang YZ, Park J, McDannold N. Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improve outcomes in a rat glioma model. J Control Release. 2013 Jul 10; 169(1-2):103-11.
    View in: PubMed
    Score: 0.151
  17. Arvanitis CD, Livingstone MS, Vykhodtseva N, McDannold N. Controlled ultrasound-induced blood-brain barrier disruption using passive acoustic emissions monitoring. PLoS One. 2012; 7(9):e45783.
    View in: PubMed
    Score: 0.145
  18. Park EJ, Zhang YZ, Vykhodtseva N, McDannold N. Ultrasound-mediated blood-brain/blood-tumor barrier disruption improves outcomes with trastuzumab in a breast cancer brain metastasis model. J Control Release. 2012 Nov 10; 163(3):277-84.
    View in: PubMed
    Score: 0.145
  19. Park J, Zhang Y, Vykhodtseva N, Akula JD, McDannold NJ. Targeted and reversible blood-retinal barrier disruption via focused ultrasound and microbubbles. PLoS One. 2012; 7(8):e42754.
    View in: PubMed
    Score: 0.144
  20. Park J, Zhang Y, Vykhodtseva N, Jolesz FA, McDannold NJ. The kinetics of blood brain barrier permeability and targeted doxorubicin delivery into brain induced by focused ultrasound. J Control Release. 2012 Aug 20; 162(1):134-42.
    View in: PubMed
    Score: 0.142
  21. McDannold N, Arvanitis CD, Vykhodtseva N, Livingstone MS. Temporary disruption of the blood-brain barrier by use of ultrasound and microbubbles: safety and efficacy evaluation in rhesus macaques. Cancer Res. 2012 Jul 15; 72(14):3652-63.
    View in: PubMed
    Score: 0.141
  22. Vykhodtseva N, McDannold N, Hynynen K. Progress and problems in the application of focused ultrasound for blood-brain barrier disruption. Ultrasonics. 2008 Aug; 48(4):279-96.
    View in: PubMed
    Score: 0.107
  23. McDannold N, Vykhodtseva N, Hynynen K. Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption. Ultrasound Med Biol. 2008 Jun; 34(6):930-7.
    View in: PubMed
    Score: 0.106
  24. McDannold N, Vykhodtseva N, Hynynen K. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med Biol. 2008 May; 34(5):834-40.
    View in: PubMed
    Score: 0.105
  25. McDannold N, Vykhodtseva N, Hynynen K. Use of ultrasound pulses combined with Definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med Biol. 2007 Apr; 33(4):584-90.
    View in: PubMed
    Score: 0.099
  26. Vykhodtseva N, McDannold N, Hynynen K. Induction of apoptosis in vivo in the rabbit brain with focused ultrasound and Optison. Ultrasound Med Biol. 2006 Dec; 32(12):1923-9.
    View in: PubMed
    Score: 0.097
  27. McDannold NJ, Vykhodtseva NI, Hynynen K. Microbubble contrast agent with focused ultrasound to create brain lesions at low power levels: MR imaging and histologic study in rabbits. Radiology. 2006 Oct; 241(1):95-106.
    View in: PubMed
    Score: 0.096
  28. McDannold N, Vykhodtseva N, Hynynen K. Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys Med Biol. 2006 Feb 21; 51(4):793-807.
    View in: PubMed
    Score: 0.091
  29. McDannold N, Vykhodtseva N, Raymond S, Jolesz FA, Hynynen K. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med Biol. 2005 Nov; 31(11):1527-37.
    View in: PubMed
    Score: 0.090
  30. Hynynen K, McDannold N, Sheikov NA, Jolesz FA, Vykhodtseva N. Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage. 2005 Jan 01; 24(1):12-20.
    View in: PubMed
    Score: 0.085
  31. McDannold N, Vykhodtseva N, Jolesz FA, Hynynen K. MRI investigation of the threshold for thermally induced blood-brain barrier disruption and brain tissue damage in the rabbit brain. Magn Reson Med. 2004 May; 51(5):913-23.
    View in: PubMed
    Score: 0.081
  32. McDannold N, Fossheim SL, Rasmussen H, Martin H, Vykhodtseva N, Hynynen K. Heat-activated liposomal MR contrast agent: initial in vivo results in rabbit liver and kidney. Radiology. 2004 Mar; 230(3):743-52.
    View in: PubMed
    Score: 0.080
  33. Hynynen K, McDannold N, Martin H, Jolesz FA, Vykhodtseva N. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). Ultrasound Med Biol. 2003 Mar; 29(3):473-81.
    View in: PubMed
    Score: 0.075
  34. Vykhodtseva N, McDannold N, Martin H, Bronson RT, Hynynen K. Apoptosis in ultrasound-produced threshold lesions in the rabbit brain. Ultrasound Med Biol. 2001 Jan; 27(1):111-7.
    View in: PubMed
    Score: 0.064
  35. Peng C, Sun T, Vykhodtseva N, Power C, Zhang Y, Mcdannold N, Porter T. Intracranial Non-thermal Ablation Mediated by Transcranial Focused Ultrasound and Phase-Shift Nanoemulsions. Ultrasound Med Biol. 2019 08; 45(8):2104-2117.
    View in: PubMed
    Score: 0.057
  36. Crake C, Papademetriou IT, Zhang Y, Vykhodtseva N, McDannold NJ, Porter TM. Simultaneous Passive Acoustic Mapping and Magnetic Resonance Thermometry for Monitoring of Cavitation-Enhanced Tumor Ablation in Rabbits Using Focused Ultrasound and Phase-Shift Nanoemulsions. Ultrasound Med Biol. 2018 12; 44(12):2609-2624.
    View in: PubMed
    Score: 0.055
  37. Kopechek JA, Park EJ, Zhang YZ, Vykhodtseva NI, McDannold NJ, Porter TM. Cavitation-enhanced MR-guided focused ultrasound ablation of rabbit tumors in vivo using phase shift nanoemulsions. Phys Med Biol. 2014 Jul 07; 59(13):3465-81.
    View in: PubMed
    Score: 0.041
  38. Treat LH, McDannold N, Zhang Y, Vykhodtseva N, Hynynen K. Improved anti-tumor effect of liposomal doxorubicin after targeted blood-brain barrier disruption by MRI-guided focused ultrasound in rat glioma. Ultrasound Med Biol. 2012 Oct; 38(10):1716-25.
    View in: PubMed
    Score: 0.036
  39. Treat LH, McDannold N, Vykhodtseva N, Zhang Y, Tam K, Hynynen K. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int J Cancer. 2007 Aug 15; 121(4):901-7.
    View in: PubMed
    Score: 0.025
  40. Hynynen K, McDannold N, Vykhodtseva N, Raymond S, Weissleder R, Jolesz FA, Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J Neurosurg. 2006 Sep; 105(3):445-54.
    View in: PubMed
    Score: 0.024
  41. Hynynen K, Clement GT, McDannold N, Vykhodtseva N, King R, White PJ, Vitek S, Jolesz FA. 500-element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn Reson Med. 2004 Jul; 52(1):100-7.
    View in: PubMed
    Score: 0.020
  42. Sheikov N, McDannold N, Vykhodtseva N, Jolesz F, Hynynen K. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med Biol. 2004 Jul; 30(7):979-89.
    View in: PubMed
    Score: 0.020
  43. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Non-invasive opening of BBB by focused ultrasound. Acta Neurochir Suppl. 2003; 86:555-8.
    View in: PubMed
    Score: 0.018
  44. Hynynen K, McDannold N, Vykhodtseva N, Jolesz FA. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology. 2001 Sep; 220(3):640-6.
    View in: PubMed
    Score: 0.017
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.