Harvard Catalyst Profiles

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Matthew M Schaefers, Ph.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R21AI159211 (SCHAEFERS, MATTHEW M) Mar 17, 2021 - Feb 28, 2023
    Identification of novel anti-virulence compounds against Pathogenic Burkholderia
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chung H, Merakou C, Schaefers MM, Flett KB, Martini S, Lu R, Blumenthal JA, Webster SS, Cross AR, Al Ahmar R, Halpin E, Anderson M, Moore NS, Snesrud EC, Yu HD, Goldberg JB, O'Toole GA, McGann P, Stam JA, Hinkle M, McAdam AJ, Kishony R, Priebe GP. Rapid expansion and extinction of antibiotic resistance mutations during treatment of acute bacterial respiratory infections. Nat Commun. 2022 03 09; 13(1):1231. PMID: 35264582.
    Citations:    Fields:    
  2. Schaefers MM, Wang BX, Boisvert NM, Martini SJ, Bonney SL, Marshall CW, Laub MT, Cooper VS, Priebe GP. Evolution towards Virulence in a Burkholderia Two-Component System. mBio. 2021 08 31; 12(4):e0182321. PMID: 34372701.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Schaefers MM. Regulation of Virulence by Two-Component Systems in Pathogenic Burkholderia. Infect Immun. 2020 06 22; 88(7). PMID: 32284365.
    Citations: 5     Fields:    Translation:HumansCells
  4. Merakou C, Schaefers MM, Priebe GP. Progress Toward the Elusive Pseudomonas aeruginosa Vaccine. Surg Infect (Larchmt). 2018 Nov/Dec; 19(8):757-768. PMID: 30388058.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  5. Schaefers MM, Duan B, Mizrahi B, Lu R, Reznor G, Kohane DS, Priebe GP. PLGA-encapsulation of the Pseudomonas aeruginosa PopB vaccine antigen improves Th17 responses and confers protection against experimental acute pneumonia. Vaccine. 2018 11 12; 36(46):6926-6932. PMID: 30314911.
    Citations: 10     Fields:    Translation:AnimalsCells
  6. Roux D, Schaefers M, Clark BS, Weatherholt M, Renaud D, Scott D, LiPuma JJ, Priebe G, Gerard C, Yoder-Himes DR. A putative lateral flagella of the cystic fibrosis pathogen Burkholderia dolosa regulates swimming motility and host cytokine production. PLoS One. 2018; 13(1):e0189810. PMID: 29346379.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Koutsogiannaki S, Schaefers MM, Okuno T, Ohba M, Yokomizo T, Priebe GP, DiNardo JA, Sulpicio SG, Yuki K. From the Cover: Prolonged Exposure to Volatile Anesthetic Isoflurane Worsens the Outcome of Polymicrobial Abdominal Sepsis. Toxicol Sci. 2017 04 01; 156(2):402-411. PMID: 28003439.
    Citations: 26     Fields:    Translation:Animals
  8. Chamberlain M, Koutsogiannaki S, Schaefers M, Babazada H, Liu R, Yuki K. The Differential Effects of Anesthetics on Bacterial Behaviors. PLoS One. 2017; 12(1):e0170089. PMID: 28099463.
    Citations: 3     Fields:    Translation:Cells
  9. Schaefers MM, Liao TL, Boisvert NM, Roux D, Yoder-Himes D, Priebe GP. An Oxygen-Sensing Two-Component System in the Burkholderia cepacia Complex Regulates Biofilm, Intracellular Invasion, and Pathogenicity. PLoS Pathog. 2017 01; 13(1):e1006116. PMID: 28046077.
    Citations: 18     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  10. Schaefers MM, Breshears LM, Anderson MJ, Lin YC, Grill AE, Panyam J, Southern PJ, Schlievert PM, Peterson ML. Epithelial proinflammatory response and curcumin-mediated protection from staphylococcal toxic shock syndrome toxin-1. PLoS One. 2012; 7(3):e32813. PMID: 22431984.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  11. Spaulding AR, Satterwhite EA, Lin YC, Chuang-Smith ON, Frank KL, Merriman JA, Schaefers MM, Yarwood JM, Peterson ML, Schlievert PM. Comparison of Staphylococcus aureus strains for ability to cause infective endocarditis and lethal sepsis in rabbits. Front Cell Infect Microbiol. 2012; 2:18. PMID: 22919610.
    Citations: 23     Fields:    Translation:AnimalsCells
  12. Strandberg KL, Peterson ML, Schaefers MM, Case LC, Pack MC, Chase DJ, Schlievert PM. Reduction in Staphylococcus aureus growth and exotoxin production and in vaginal interleukin 8 levels due to glycerol monolaurate in tampons. Clin Infect Dis. 2009 Dec 01; 49(11):1711-7. PMID: 19863450.
    Citations: 19     Fields:    Translation:HumansCells
  13. Lin YC, Schlievert PM, Anderson MJ, Fair CL, Schaefers MM, Muthyala R, Peterson ML. Glycerol monolaurate and dodecylglycerol effects on Staphylococcus aureus and toxic shock syndrome toxin-1 in vitro and in vivo. PLoS One. 2009 Oct 19; 4(10):e7499. PMID: 19838303.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  14. Brosnahan AJ, Schaefers MM, Amundson WH, Mantz MJ, Squier CA, Peterson ML, Schlievert PM. Novel toxic shock syndrome toxin-1 amino acids required for biological activity. Biochemistry. 2008 Dec 09; 47(49):12995-3003. PMID: 19012411.
    Citations: 15     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.