Harvard Catalyst Profiles

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Ariela Rivkah Orkaby, M.D.


Ben Gurion University, IsraelMD05/2010
Boston University Medical Center, Boston, MA07/2013Internal Medicine
Beth Israel Deaconess Medical Center, Boston, MA06/2014Geriatric Medicine
VA Boston Healthcare System/Brigham & Women's Hospital, Boston, MA06/2016Preventive Cardiology
Harvard T. H. Chan School of Public Health, Boston, MAMPH05/2016Epidemiology
Best Poster Award, American Geriatrics Society Annual Meeting
Young Investigator Travel Award, American College of Cardiology/American Geriatric Society
Finalist (3rd place), Jay D. Coffman Early Career Investigator Award, American Heart Association
Faculty Career Development Award, Brigham Research Institute


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. IK2CX001800 (ORKABY, ARIELA R) Jan 1, 2019 - Dec 31, 2023
    Statins for Primary Preventive of Cardiovascular Disease and Frailty
    Role: Principal Investigator
  2. R03AG060169 (ORKABY, ARIELA R) Aug 1, 2018 - Jul 31, 2020
    Frailty, Statins, and Cardiovascular Disease Burden in Older Adults
    Role: Principal Investigator
  3. BRI-FCDA (ORKABY, ARIELA R) Jul 1, 2018 - Jun 30, 2019
    Brigham Research Institute Faculty Career Development Award/Eleanor and Miles Shore 50th Anniversary Fellowship Program for Scholars in Medicine at Harvard Medical School
    Association between non-steroidal anti-inflammatory drug use, frailty, and function in older men
    Role: PI
  4. P30AG031679 (BHASIN, SHALENDER) Jul 1, 2017 - Jun 30, 2019
    Is Aspirin Use Associated with a Decreased Risk of Frailty and Functional Limitation in Older Men?
    Role: CDA PI
  5. Jul 1, 2014 - Jun 30, 2016
    John A. Hartford Foundation Center of Excellence in Geriatric Medicine and Training

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Orkaby AR, James K, Leuchtenburg J, Solooki E, Gaziano JM, Driver JA. Taking prevention to the next step: implementation of a brief, sustainable frailty assessment in a cardiology clinic. BMJ Open Qual. 2021 Jan; 10(1). PMID: 33408100.
  2. Orkaby AR, Kornej J, Lubitz SA, McManus DD, Travison TG, Sherer JA, Trinquart L, Murabito JM, Benjamin EJ, Preis SR. Association Between Frailty and Atrial Fibrillation in Older Adults: The Framingham Heart Study Offspring Cohort. J Am Heart Assoc. 2021 Jan 05; 10(1):e018557. PMID: 33372538.
  3. Loewenthal J, DuMontier C, Cooper L, Frain L, Waldman LS, Streiter S, Cardin K, Tulebaev S, Javedan H, Orkaby AR, Hshieh T. Adaptation of the comprehensive geriatric assessment to a virtual delivery format. Age Ageing. 2020 Dec 05. PMID: 33284967.
  4. Yourman LC, Cenzer IS, Boscardin WJ, Nguyen BT, Smith AK, Schonberg MA, Schoenborn NL, Widera EW, Orkaby A, Rodriguez A, Lee SJ. Evaluation of Time to Benefit of Statins for the Primary Prevention of Cardiovascular Events in Adults Aged 50 to 75 Years: A Meta-analysis. JAMA Intern Med. 2020 Nov 16. PMID: 33196766.
  5. Orkaby AR, Gagnon DR, Djousse L. New Statin Use and Mortality in Older Veterans-Reply. JAMA. 2020 11 10; 324(18):1908-1909. PMID: 33170238.
  6. O’Mara, L, Streiter S, Orkaby, AR, Ouchi K, Bernacki R. A Framework to Triage Older Adults with COVID-19 to Provide Patient Centered Care. NEJM Catalyst Innovations in Care Delivery. 2020. View Publication.
  7. Sokas CM, Cowan J, Dalton MK, Coogan K, Bader A, Bernacki R, Orkaby AR, Cooper Z. Association Between Patient-Reported Frailty and Non-Home Discharge Among Older Adults Undergoing Surgery. J Am Geriatr Soc. 2020 Dec; 68(12):2909-2913. PMID: 33031587.
    Citations:    Fields:    
  8. Orkaby AR, Yang L, Dufour AB, Travison TG, Sesso HD, Driver JA, Djousse L, Gaziano JM. Association Between Long-Term Aspirin Use and Frailty in Men: The Physicians' Health Study. J Gerontol A Biol Sci Med Sci. 2020 Sep 11. PMID: 32918079.
    Citations:    Fields:    
  9. James K, Orkaby AR, Schwartz AW. Foot Examination for Older Adults. Am J Med. 2021 Jan; 134(1):30-35. PMID: 32805226.
    Citations:    Fields:    
  10. Orkaby AR, Driver JA, Ho YL, Lu B, Costa L, Honerlaw J, Galloway A, Vassy JL, Forman DE, Gaziano JM, Gagnon DR, Wilson PWF, Cho K, Djousse L. Association of Statin Use With All-Cause and Cardiovascular Mortality in US Veterans 75 Years and Older. JAMA. 2020 07 07; 324(1):68-78. PMID: 32633800.
    Citations:    Fields:    Translation:Humans
  11. Vassy JL, Lu B, Ho YL, Galloway A, Raghavan S, Honerlaw J, Tarko L, Russo J, Qazi S, Orkaby AR, Tanukonda V, Djousse L, Gaziano JM, Gagnon DR, Cho K, Wilson PWF. Estimation of Atherosclerotic Cardiovascular Disease Risk Among Patients in the Veterans Affairs Health Care System. JAMA Netw Open. 2020 07 01; 3(7):e208236. PMID: 32662843.
    Citations:    Fields:    
  12. Streiter S, Gaziano JM, Orkaby AR. Maximizing the Mini-Cog: Cognitive Decline Caused by Carotid Artery Stenosis. Arch Clin Med Case Rep. 2020; 4(3):456-458. PMID: 32656503.
  13. Orkaby AR. The Highs and Lows of Cholesterol: A Paradox of Healthy Aging? J Am Geriatr Soc. 2020 02; 68(2):236-237. PMID: 31930729.
    Citations:    Fields:    
  14. Ward RE, Orkaby AR, Chen J, Hshieh TT, Driver JA, Gaziano JM, Djousse L. Association between Diet Quality and Frailty Prevalence in the Physicians' Health Study. J Am Geriatr Soc. 2020 Apr; 68(4):770-776. PMID: 31840808.
    Citations: 1     Fields:    
  15. Orkaby AR, Djousse L, Manson JE. Vitamin D supplements and prevention of cardiovascular disease. Curr Opin Cardiol. 2019 11; 34(6):700-705. PMID: 31425172.
    Citations:    Fields:    Translation:Humans
  16. Goyal P, Anderson TS, Bernacki GM, Marcum ZA, Orkaby AR, Kim D, Zullo A, Krishnaswami A, Weissman A, Steinman MA, Rich MW. Physician Perspectives on Deprescribing Cardiovascular Medications for Older Adults. J Am Geriatr Soc. 2020 01; 68(1):78-86. PMID: 31509233.
    Citations: 2     Fields:    Translation:Humans
  17. Imran TF, Orkaby A, Chen J, Selvaraj S, Driver JA, Gaziano JM, Djoussé L. Walking pace is inversely associated with risk of death and cardiovascular disease: The Physicians' Health Study. Atherosclerosis. 2019 10; 289:51-56. PMID: 31450014.
    Citations: 1     Fields:    Translation:Humans
  18. Hawley CE, Roefaro J, Forman DE, Orkaby AR. Statins for Primary Prevention in Those Aged 70 Years and Older: A Critical Review of Recent Cholesterol Guidelines. Drugs Aging. 2019 08; 36(8):687-699. PMID: 31049807.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  19. Orkaby AR, Nussbaum L, Ho YL, Gagnon D, Quach L, Ward R, Quaden R, Yaksic E, Harrington K, Paik JM, Kim DH, Wilson PW, Gaziano JM, Djousse L, Cho K, Driver JA. The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002-2012. J Gerontol A Biol Sci Med Sci. 2019 07 12; 74(8):1257-1264. PMID: 30307533.
    Citations: 11     Fields:    Translation:Humans
  20. Chen MY, Orkaby AR, Rosenberg MA, Driver JA. Frailty, Implantable Cardioverter Defibrillators, and Mortality: a Systematic Review. J Gen Intern Med. 2019 10; 34(10):2224-2231. PMID: 31264082.
    Citations: 2     Fields:    
  21. Streiter S, Orkaby AR. "Like a Man of 70 Years": Aging and the Words We Use. J Am Geriatr Soc. 2019 10; 67(10):2208-2209. PMID: 31112284.
    Citations:    Fields:    Translation:Humans
  22. Wei LJ, Sun R, Orkaby AR, Kim DH, Zhu H. Biodegradable-polymer stents versus durable-polymer stents. Lancet. 2019 05 11; 393(10184):1932-1933. PMID: 31084958.
    Citations:    Fields:    
  23. Imran TF, Kurgansky KE, Patel YR, Orkaby AR, McLean RR, Ho YL, Cho K, Gaziano JM, Djousse L, Gagnon DR, Joseph J. Serial sodium values and adverse outcomes in heart failure with preserved ejection fraction. Int J Cardiol. 2019 09 01; 290:119-124. PMID: 30929975.
    Citations: 1     Fields:    Translation:Humans
  24. Orkaby AR, Lunetta KL, Sun FJ, Driver JA, Benjamin EJ, Hamburg NM, Mitchell GF, Vasan RS, Murabito JM. Cross-Sectional Association of Frailty and Arterial Stiffness in Community-Dwelling Older Adults: The Framingham Heart Study. J Gerontol A Biol Sci Med Sci. 2019 02 15; 74(3):373-379. PMID: 29917058.
    Citations: 3     Fields:    Translation:Humans
  25. Bean JF, Orkaby AR, Driver JA. Geriatric Rehabilitation Should Not Be an Oxymoron: A Path Forward. Arch Phys Med Rehabil. 2019 05; 100(5):995-1000. PMID: 30735624.
    Citations:    Fields:    Translation:Humans
  26. Yaksic E, Lecky V, Sharnprapai S, Tungkhar T, Cho K, Driver JA, Orkaby AR. Defining Frailty in Research Abstracts: A Systematic Review and Recommendations for Standardization. J Frailty Aging. 2019; 8(2):67-71. PMID: 30997918.
    Citations:    Fields:    Translation:Humans
  27. Goyal P, Alpert C, Orkaby AR. Time to Get Going on Involving FITs in Clinical Trials. J Am Coll Cardiol. 2018 12 04; 72(22):2802-2805. PMID: 30497566.
    Citations:    Fields:    Translation:Humans
  28. Panayi AC, Orkaby AR, Sakthivel D, Endo Y, Varon D, Roh D, Orgill DP, Neppl RL, Javedan H, Bhasin S, Sinha I. Impact of frailty on outcomes in surgical patients: A systematic review and meta-analysis. Am J Surg. 2019 08; 218(2):393-400. PMID: 30509455.
    Citations: 4     Fields:    Translation:Humans
  29. Orkaby AR, Rich MW, Sun R, Lux E, Wei LJ, Kim DH. Pravastatin for Primary Prevention in Older Adults: Restricted Mean Survival Time Analysis. J Am Geriatr Soc. 2018 10; 66(10):1987-1991. PMID: 30251369.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  30. Schwartz A, Orkaby A. Toenail Examination Reveals Unmet Care Needs-Reply. JAMA Intern Med. 2018 09 01; 178(9):1283. PMID: 30193249.
    Citations:    Fields:    
  31. McCaw ZR, Orkaby AR, Wei LJ, Kim DH, Rich MW. Applying Evidence-Based Medicine to Shared Decision Making: Value of Restricted MeanSurvival Time. Am J Med. 2019 01; 132(1):13-15. PMID: 30076822.
    Citations:    Fields:    Translation:Humans
  32. Patel YR, Robbins JM, Kurgansky KE, Imran T, Orkaby AR, McLean RR, Ho YL, Cho K, Michael Gaziano J, Djousse L, Gagnon DR, Joseph J. Development and validation of a heart failure with preserved ejection fraction cohort using electronic medical records. BMC Cardiovasc Disord. 2018 06 28; 18(1):128. PMID: 29954337.
    Citations: 2     Fields:    Translation:Humans
  33. Patel YR, Kurgansky KE, Imran TF, Orkaby AR, McLean RR, Ho YL, Cho K, Gaziano JM, Djousse L, Gagnon DR, Joseph J. Prognostic Significance of Baseline Serum Sodium in Heart Failure With Preserved Ejection Fraction. J Am Heart Assoc. 2018 06 13; 7(12). PMID: 29899018.
    Citations: 1     Fields:    Translation:Humans
  34. Orkaby AR, Schwartz AW. Toenails as the "Hemoglobin A1c" of Functional Independence-Beyond the Polished Wingtips. JAMA Intern Med. 2018 05 01; 178(5):598-599. PMID: 29630696.
    Citations:    Fields:    Translation:Humans
  35. Orkaby AR. Backwards and Forwards. J Gen Intern Med. 2018 02; 33(2):233-234. PMID: 29192389.
    Citations:    Fields:    Translation:Humans
  36. Orkaby AR, Onuma O, Qazi S, Gaziano JM, Driver JA. Preventing cardiovascular disease in older adults: One size does not fit all. Cleve Clin J Med. 2018 Jan; 85(1):55-64. PMID: 29328899.
    Citations:    Fields:    Translation:Humans
  37. Orkaby AR, Forman DE. Physical activity and CVD in older adults: an expert's perspective. Expert Rev Cardiovasc Ther. 2018 Jan; 16(1):1-10. PMID: 29256628.
    Citations: 7     Fields:    Translation:Humans
  38. Orkaby AR, Rich MW. Cardiovascular Screening and Primary Prevention in Older Adults. Clin Geriatr Med. 2018 02; 34(1):81-93. PMID: 29129219.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  39. Orkaby AR, Cho K, Cormack J, Gagnon DR, Driver JA. Metformin vs sulfonylurea use and risk of dementia in US veterans aged =65 years with diabetes. Neurology. 2017 Oct 31; 89(18):1877-1885. PMID: 28954880.
    Citations: 17     Fields:    Translation:Humans
  40. Orkaby AR, Gaziano JM, Djousse L, Driver JA. Statins for Primary Prevention of Cardiovascular Events and Mortality in Older Men. J Am Geriatr Soc. 2017 Nov; 65(11):2362-2368. PMID: 28892121.
    Citations: 9     Fields:    Translation:Humans
  41. Orkaby AR, Hshieh TT, Gaziano JM, Djousse L, Driver JA. Comparison of two frailty indices in the physicians' health study. Arch Gerontol Geriatr. 2017 Jul; 71:21-27. PMID: 28242579.
    Citations: 2     Fields:    Translation:Humans
  42. Orkaby AR, Ozonoff A, Reisman JI, Miller DR, Zhao S, Rose AJ. Continued Use of Warfarin in Veterans with Atrial Fibrillation After Dementia Diagnosis. J Am Geriatr Soc. 2017 Feb; 65(2):249-256. PMID: 28039854.
    Citations: 8     Fields:    Translation:Humans
  43. Orkaby AR, Forman DE. Assessing Risks and Benefits of Invasive Cardiac Procedures in Patients with Advanced Multimorbidity. Clin Geriatr Med. 2016 05; 32(2):359-71. PMID: 27113152.
    Citations: 1     Fields:    Translation:Humans
  44. Orkaby AR, Chen B, Iliaki EF, Sulis CA, Oates DJ. A curious case of Lactobacillus casei in a prosthetic joint: was it the yogurt? J Am Geriatr Soc. 2012 Jun; 60(6):1177-8. PMID: 22690992.
    Citations: 2     Fields:    Translation:HumansCells
  45. Geller JS, Orkaby A, Cleghorn GD. Impact of a group medical visit program on Latino health-related quality of life. Explore (NY). 2011 Mar-Apr; 7(2):94-9. PMID: 21397870.
    Citations: 11     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.