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profileMarcos Francisco Vidal Melo, PH.D., M.D.

TitleProfessor of Anaesthesia
InstitutionMassachusetts General Hospital
DepartmentAnaesthesia
AddressMassachusetts General Hospital
Anesthesia & Critical Care
55 Fruit St
Boston MA 02114
Phone617/726-3030
Fax617/726-7536
vCardDownload vCard (login for email)

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R34HL123438     (VIDAL MELO, MARCOS F)Jul 15, 2015 - Mar 31, 2018
NIH/NHLBI
Intraoperative Protective Ventilation and Postoperative Pulmonary Complications
Role: Principal Investigator

R01HL121228     (VIDAL MELO, MARCOS F)Jan 1, 2014 - Dec 31, 2017
NIH/NHLBI
Regional Tidal Lung Strain and Neutrophilic Inflammation in Early Lung Injury
Role: Principal Investigator

R01HL086827     (VIDAL MELO, MARCOS F)Jan 10, 2007 - Dec 31, 2013
NIH/NHLBI
PET Imaging of Local Inflammation and Function in Ventilator Induced Lung Injury
Role: Principal Investigator

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Fernandez-Bustamante A, Schoen J, Vidal Melo MF. Incentive Spirometry After Bariatric Surgery: The Importance of Patient Compliance. JAMA Surg. 2017 Jun 21. PMID: 28636722.
    View in: PubMed
  2. D'Antini D, Huhle R, Herrmann J, Sulemanji DS, Oto J, Raimondo P, Mirabella L, Hemmes SNT, Schultz MJ, Pelosi P, Kaczka DW, Vidal Melo MF, Gama de Abreu M, Cinnella G. Respiratory System Mechanics During Low Versus High Positive End-Expiratory Pressure in Open Abdominal Surgery: A Substudy of PROVHILO Randomized Controlled Trial. Anesth Analg. 2017 Jun 19. PMID: 28632529.
    View in: PubMed
  3. Fernandez-Bustamante A, Vidal Melo MF. The Increasing Call for Protective Ventilation During Anesthesia-Reply. JAMA Surg. 2017 Jun 07. PMID: 28593302.
    View in: PubMed
  4. Bluth T, Teichmann R, Kiss T, Bobek I, Canet J, Cinnella G, De Baerdemaeker L, Gregoretti C, Hedenstierna G, Hemmes SN, Hiesmayr M, Hollmann MW, Jaber S, Laffey JG, Licker MJ, Markstaller K, Matot I, Müller G, Mills GH, Mulier JP, Putensen C, Rossaint R, Schmitt J, Senturk M, Neto AS, Severgnini P, Sprung J, Vidal Melo MF, Wrigge H, Schultz MJ, Pelosi P, Gama de Abreu M. Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial. Trials. 2017 Jun 01; 18(1):247. PMID: 28571581.
    View in: PubMed
  5. Bluth T, Teichmann R, Kiss T, Bobek I, Canet J, Cinnella G, De Baerdemaeker L, Gregoretti C, Hedenstierna G, Hemmes SN, Hiesmayr M, Hollmann MW, Jaber S, Laffey JG, Licker MJ, Markstaller K, Matot I, Müller G, Mills GH, Mulier JP, Putensen C, Rossaint R, Schmitt J, Senturk M, Serpa Neto A, Severgnini P, Sprung J, Vidal Melo MF, Wrigge H, Schultz MJ, Pelosi P, Gama de Abreu M. Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial. Trials. 2017 Apr 28; 18(1):202. PMID: 28454590.
    View in: PubMed
  6. Güldner A, Braune A, Ball L, Leme Silva P, Samary C, Insorsi A, Huhle R, Rentzsch I, Becker C, Oehme L, Andreeff M, Vidal Melo MF, Winkler T, Pelosi P, Rieken Macedo Rocco P, Kotzerke J, Gama de Abreu M. The authors reply. Crit Care Med. 2017 Mar; 45(3):e328-e329. PMID: 28212230.
    View in: PubMed
  7. Fernandez-Bustamante A, Frendl G, Sprung J, Kor DJ, Subramaniam B, Martinez Ruiz R, Lee JW, Henderson WG, Moss A, Mehdiratta N, Colwell MM, Bartels K, Kolodzie K, Giquel J, Vidal Melo MF. Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. JAMA Surg. 2017 Feb 01; 152(2):157-166. PMID: 27829093.
    View in: PubMed
  8. Wellman TJ, de Prost N, Tucci M, Winkler T, Baron RM, Filipczak P, Raby B, Chu JH, Harris RS, Musch G, Dos Reis Falcao LF, Capelozzi V, Venegas JG, Vidal Melo MF. Lung Metabolic Activation as an Early Biomarker of Acute Respiratory Distress Syndrome and Local Gene Expression Heterogeneity. Anesthesiology. 2016 Nov; 125(5):992-1004. PMID: 27611185.
    View in: PubMed
  9. Güldner A, Braune A, Ball L, Silva PL, Samary C, Insorsi A, Huhle R, Rentzsch I, Becker C, Oehme L, Andreeff M, Vidal Melo MF, Winkler T, Pelosi P, Rocco PR, Kotzerke J, Gama de Abreu M. Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome. Crit Care Med. 2016 Sep; 44(9):e854-65. PMID: 27035236.
    View in: PubMed
  10. de Jong MAC, Ladha KS, Vidal Melo MF, Staehr-Rye AK, Bittner EA, Kurth T, Eikermann M. Differential Effects of Intraoperative Positive End-expiratory Pressure (PEEP) on Respiratory Outcome in Major Abdominal Surgery Versus Craniotomy. Ann Surg. 2016 Aug; 264(2):362-369. PMID: 26496082; PMCID: PMC4841734 [Available on 08/01/17].
  11. Paula LF, Wellman TJ, Winkler T, Spieth PM, Güldner A, Venegas JG, Gama de Abreu M, Carvalho AR, Vidal Melo MF. Regional tidal lung strain in mechanically ventilated normal lungs. J Appl Physiol (1985). 2016 Dec 01; 121(6):1335-1347. PMID: 27445302.
    View in: PubMed
  12. Freitas CR, Malbouisson LM, Benicio A, Negri EM, Bini FM, Massoco CO, Otsuki DA, Melo MF, Carmona MJ. Lung Perfusion and Ventilation During Cardiopulmonary Bypass Reduces Early Structural Damage to Pulmonary Parenchyma. Anesth Analg. 2016 Apr; 122(4):943-52. PMID: 26991612.
    View in: PubMed
  13. Ladha K, Vidal Melo MF, McLean DJ, Wanderer JP, Grabitz SD, Kurth T, Eikermann M. Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study. BMJ. 2015 Jul 14; 351:h3646. PMID: 26174419; PMCID: PMC4501577.
  14. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015 May 06; 15:56. PMID: 25907273; PMCID: PMC4491899.
  15. Wellman TJ, Winkler T, Vidal Melo MF. Modeling of Tracer Transport Delays for Improved Quantification of Regional Pulmonary ¹8F-FDG Kinetics, Vascular Transit Times, and Perfusion. Ann Biomed Eng. 2015 Nov; 43(11):2722-34. PMID: 25940652; PMCID: PMC4618094 [Available on 11/01/16].
  16. Wiener-Kronish JP, Vidal Melo MF. New investigations of core competencies: perioperative mechanical ventilation and assessment of lung function. Anesthesiology. 2015 Apr; 122(4):723-4. PMID: 25668412; PMCID: PMC4644128.
  17. Wanderer JP, Ehrenfeld JM, Epstein RH, Kor DJ, Bartz RR, Fernandez-Bustamante A, Vidal Melo MF, Blum JM. Temporal trends and current practice patterns for intraoperative ventilation at U.S. academic medical centers: a retrospective study. BMC Anesthesiol. 2015; 15:40. PMID: 25852301; PMCID: PMC4387596.
  18. de Prost N, Feng Y, Wellman T, Tucci MR, Costa EL, Musch G, Winkler T, Harris RS, Venegas JG, Chao W, Vidal Melo MF. 18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome. J Nucl Med. 2014 Nov; 55(11):1871-7. PMID: 25286924; PMCID: PMC4258066.
  19. Costa EL, Vidal Melo MF. Diaphragmatic electrical activity: a new tool to assess lung hyperinflation? Anesthesiology. 2014 Sep; 121(3):447-9. PMID: 25046571; PMCID: PMC4165652.
  20. Badgaiyan RD, Weise S, Wack DS, Vidal Melo MF. Attenuation of regional cerebral blood flow during memory processing after coronary artery bypass surgery. Anesth Analg. 2014 Sep; 119(3):550-3. PMID: 24977634; PMCID: PMC4139436.
  21. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Zheng H, Venegas JG, Vidal Melo MF. Effect of local tidal lung strain on inflammation in normal and lipopolysaccharide-exposed sheep*. Crit Care Med. 2014 Jul; 42(7):e491-500. PMID: 24758890; PMCID: PMC4123638.
  22. Musch G, Winkler T, Harris RS, Vidal Melo MF, Wellman TJ, de Prost N, Kradin RL, Venegas JG. Lung [(18)F]fluorodeoxyglucose uptake and ventilation-perfusion mismatch in the early stage of experimental acute smoke inhalation. Anesthesiology. 2014 Mar; 120(3):683-93. PMID: 24051392; PMCID: PMC4129461.
  23. Eikermann M, Vidal Melo MF. Therapeutic range of spontaneous breathing during mechanical ventilation. Anesthesiology. 2014 Mar; 120(3):536-9. PMID: 24424072; PMCID: PMC3985085.
  24. de Prost N, Costa EL, Wellman T, Musch G, Tucci MR, Winkler T, Harris R, Venegas JG, Kavanagh BP, Vidal Melo MF. Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care. 2013 Aug 15; 17(4):R175. PMID: 23947920; PMCID: PMC4056777.
  25. Kang S, Singh J, Vidal Melo M, Gulur P. Spinal cord stimulation for intercostal neuralgia in a patient with implantable cardiac defibrillator and biventricular pacing. Neuromodulation. 2014 Jun; 17(4):386-8. PMID: 23837496.
    View in: PubMed
  26. Saha D, Takahashi K, de Prost N, Winkler T, Pinilla-Vera M, Baron RM, Vidal Melo MF. Micro-autoradiographic assessment of cell types contributing to 2-deoxy-2-[(18)F]fluoro-D-glucose uptake during ventilator-induced and endotoxemic lung injury. Mol Imaging Biol. 2013 Feb; 15(1):19-27. PMID: 22752654.
    View in: PubMed
  27. Harris RS, Fujii-Rios H, Winkler T, Musch G, Vidal Melo MF, Venegas JG. Ventilation defect formation in healthy and asthma subjects is determined by lung inflation. PLoS One. 2012; 7(12):e53216. PMID: 23285270; PMCID: PMC3532117.
  28. Dittrich AS, Winkler T, Wellman T, de Prost N, Musch G, Harris RS, Vidal Melo MF. Modeling 18F-FDG kinetics during acute lung injury: experimental data and estimation errors. PLoS One. 2012; 7(10):e47588. PMID: 23118881; PMCID: PMC3485257.
  29. Vidal Melo MF, Musch G, Kaczka DW. Pulmonary pathophysiology and lung mechanics in anesthesiology: a case-based overview. Anesthesiol Clin. 2012 Dec; 30(4):759-84. PMID: 23089508; PMCID: PMC3479443.
  30. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, Vidal Melo MF. Effect of regional lung inflation on ventilation heterogeneity at different length scales during mechanical ventilation of normal sheep lungs. J Appl Physiol (1985). 2012 Sep; 113(6):947-57. PMID: 22678958; PMCID: PMC3472483.
  31. Harris RS, Venegas JG, Wongviriyawong C, Winkler T, Kone M, Musch G, Vidal Melo MF, de Prost N, Hamilos DL, Afshar R, Cho J, Luster AD, Medoff BD. 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma. J Nucl Med. 2011 Nov; 52(11):1713-20. PMID: 21990575; PMCID: PMC3855676.
  32. Takahashi K, Saha D, Shattino I, Pavlov VI, Stahl GL, Finnegan P, Melo MF. Complement 3 is involved with ventilator-induced lung injury. Int Immunopharmacol. 2011 Dec; 11(12):2138-43. PMID: 21979496; PMCID: PMC3512097.
  33. Carvalho AR, Ichinose F, Schettino IA, Hess D, Rojas J, Giannella-Neto A, Agnihotri A, Walker J, MacGillivray TE, Vidal Melo MF. Tidal lung recruitment and exhaled nitric oxide during coronary artery bypass grafting in patients with and without chronic obstructive pulmonary disease. Lung. 2011 Dec; 189(6):499-509. PMID: 21952833.
    View in: PubMed
  34. de Prost N, Costa EL, Wellman T, Musch G, Winkler T, Tucci MR, Harris RS, Venegas JG, Vidal Melo MF. Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation. J Appl Physiol (1985). 2011 Nov; 111(5):1249-58. PMID: 21799132; PMCID: PMC3220309.
  35. de Prost N, El-Karak C, Avila M, Ichinose F, Vidal Melo MF. Changes in cysteinyl leukotrienes during and after cardiac surgery with cardiopulmonary bypass in patients with and without chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg. 2011 Jun; 141(6):1496-502.e3. PMID: 21377695; PMCID: PMC4014305.
  36. Schroeder T, Melo MF, Venegas JG. Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation. Acad Radiol. 2011 Apr; 18(4):418-23. PMID: 21292507; PMCID: PMC3114040.
  37. Ficke DJ, Lee J, Chaney MA, Bas H, Vidal-Melo MF, Stone ME. Case 6-2010: Noncardiac surgery in patients with a left ventricular assist device. J Cardiothorac Vasc Anesth. 2010 Dec; 24(6):1002-9. PMID: 21109156.
    View in: PubMed
  38. de Prost N, Tucci MR, Melo MF. Assessment of lung inflammation with 18F-FDG PET during acute lung injury. AJR Am J Roentgenol. 2010 Aug; 195(2):292-300. PMID: 20651183; PMCID: PMC3172046.
  39. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, Melo MF. Measurement of regional specific lung volume change using respiratory-gated PET of inhaled 13N-nitrogen. J Nucl Med. 2010 Apr; 51(4):646-53. PMID: 20237036; PMCID: PMC3177560.
  40. Costa EL, Musch G, Winkler T, Schroeder T, Harris RS, Jones HA, Venegas JG, Vidal Melo MF. Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep. Anesthesiology. 2010 Mar; 112(3):658-69. PMID: 20179503; PMCID: PMC2829720.
  41. Vidal Melo MF, Winkler T, Harris RS, Musch G, Greene RE, Venegas JG. Spatial heterogeneity of lung perfusion assessed with (13)N PET as a vascular biomarker in chronic obstructive pulmonary disease. J Nucl Med. 2010 Jan; 51(1):57-65. PMID: 20008987.
    View in: PubMed
  42. Costa EL, Vidal Melo MF. Lung water: what you see (with computed tomography) and what you get (with a bedside device). Anesthesiology. 2009 Nov; 111(5):933-5. PMID: 19858867; PMCID: PMC2770091.
  43. Harris RS, Winkler T, Musch G, Vidal Melo MF, Schroeder T, Tgavalekos N, Venegas JG. The prone position results in smaller ventilation defects during bronchoconstriction in asthma. J Appl Physiol (1985). 2009 Jul; 107(1):266-74. PMID: 19443742; PMCID: PMC2711796.
  44. Carvalho AR, Spieth PM, Pelosi P, Vidal Melo MF, Koch T, Jandre FC, Giannella-Neto A, de Abreu MG. Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration. Intensive Care Med. 2008 Dec; 34(12):2291-9. PMID: 18825365; PMCID: PMC3177558.
  45. Melo MF, Leone BJ. Introduction of new monitors into clinical anesthesia. Anesth Analg. 2008 Sep; 107(3):749-50. PMID: 18713878.
    View in: PubMed
  46. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Modeling pulmonary kinetics of 2-deoxy-2-[18F]fluoro-D-glucose during acute lung injury. Acad Radiol. 2008 Jun; 15(6):763-75. PMID: 18486012; PMCID: PMC2474713.
  47. Alexander JH, Emery RW, Carrier M, Ellis SJ, Mehta RH, Hasselblad V, Menasche P, Khalil A, Cote R, Bennett-Guerrero E, Mack MJ, Schuler G, Harrington RA, Tardif JC. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial. JAMA. 2008 Apr 16; 299(15):1777-87. PMID: 18381567.
    View in: PubMed
  48. Loeppky JA, Icenogle MV, Charlton GA, Conn CA, Maes D, Riboni K, Gates L, Melo MF, Roach RC. Hypoxemia and acute mountain sickness: which comes first? High Alt Med Biol. 2008; 9(4):271-9. PMID: 19115910.
    View in: PubMed
  49. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Image-derived input function for assessment of 18F-FDG uptake by the inflamed lung. J Nucl Med. 2007 Nov; 48(11):1889-96. PMID: 17942803; PMCID: PMC3172049.
  50. Musch G, Bellani G, Vidal Melo MF, Harris RS, Winkler T, Schroeder T, Venegas JG. Relation between shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2008 Feb 01; 177(3):292-300. PMID: 17932380; PMCID: PMC2218852.
  51. Chumnanvej S, Wood MJ, MacGillivray TE, Melo MF. Perioperative echocardiographic examination for ventricular assist device implantation. Anesth Analg. 2007 Sep; 105(3):583-601. PMID: 17717209.
    View in: PubMed
  52. Musch G, Venegas JG, Bellani G, Winkler T, Schroeder T, Petersen B, Harris RS, Melo MF. Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury. Anesthesiology. 2007 Apr; 106(4):723-35. PMID: 17413910.
    View in: PubMed
  53. Tgavalekos NT, Musch G, Harris RS, Vidal Melo MF, Winkler T, Schroeder T, Callahan R, Lutchen KR, Venegas JG. Relationship between airway narrowing, patchy ventilation and lung mechanics in asthmatics. Eur Respir J. 2007 Jun; 29(6):1174-81. PMID: 17360726.
    View in: PubMed
  54. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Winkler T, Venegas JG. PET imaging of regional 18F-FDG uptake and lung function after cigarette smoke inhalation. J Nucl Med. 2007 Mar; 48(3):413-9. PMID: 17332619.
    View in: PubMed
  55. Loeppky JA, Icenogle MV, Caprihan A, Vidal Melo MF, Altobelli SA. CO2 rebreathing model in COPD: blood-to-gas equilibration. Eur J Appl Physiol. 2006 Nov; 98(5):450-60. PMID: 16960726.
    View in: PubMed
  56. Harris RS, Winkler T, Tgavalekos N, Musch G, Melo MF, Schroeder T, Chang Y, Venegas JG. Regional pulmonary perfusion, inflation, and ventilation defects in bronchoconstricted patients with asthma. Am J Respir Crit Care Med. 2006 Aug 01; 174(3):245-53. PMID: 16690973; PMCID: PMC2648114.
  57. Venegas JG, Schroeder T, Harris S, Winkler RT, Melo MF. The distribution of ventilation during bronchoconstriction is patchy and bimodal: a PET imaging study. Respir Physiol Neurobiol. 2005 Aug 25; 148(1-2):57-64. PMID: 15994134.
    View in: PubMed
  58. Tgavalekos NT, Tawhai M, Harris RS, Musch G, Mush G, Vidal-Melo M, Venegas JG, Lutchen KR. Identifying airways responsible for heterogeneous ventilation and mechanical dysfunction in asthma: an image functional modeling approach. J Appl Physiol (1985). 2005 Dec; 99(6):2388-97. PMID: 16081622.
    View in: PubMed
  59. Loeppky JA, Caprihan A, Altobelli SA, Icenogle MV, Scotto P, Vidal Melo MF. Validation of a two-compartment model of ventilation/perfusion distribution. Respir Physiol Neurobiol. 2006 Mar 28; 151(1):74-92. PMID: 16024300.
    View in: PubMed
  60. Richter T, Bellani G, Scott Harris R, Vidal Melo MF, Winkler T, Venegas JG, Musch G. Effect of prone position on regional shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):480-7. PMID: 15901611; PMCID: PMC2718529.
  61. Shaff DA, Raines DE, Vidal Melo MF, King ME, Misra S, Chen LL. Anesthetic management for transurethral resection of the bladder in a 74-year-old man with uncorrected tetralogy of Fallot. J Clin Anesth. 2005 May; 17(3):198-201. PMID: 15896587.
    View in: PubMed
  62. Venegas JG, Winkler T, Musch G, Vidal Melo MF, Layfield D, Tgavalekos N, Fischman AJ, Callahan RJ, Bellani G, Harris RS. Self-organized patchiness in asthma as a prelude to catastrophic shifts. Nature. 2005 Apr 07; 434(7034):777-82. PMID: 15772676.
    View in: PubMed
  63. Melo MF, Harris RS, Layfield JD, Venegas JG. Topographic basis of bimodal ventilation-perfusion distributions during bronchoconstriction in sheep. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):714-21. PMID: 15640360.
    View in: PubMed
  64. Musch G, Harris RS, Vidal Melo MF, O'Neill KR, Layfield JD, Winkler T, Venegas JG. Mechanism by which a sustained inflation can worsen oxygenation in acute lung injury. Anesthesiology. 2004 Feb; 100(2):323-30. PMID: 14739807.
    View in: PubMed
  65. Vidal Melo MF. Clinical respiratory physiology of the neonate and infant with congenital heart disease. Int Anesthesiol Clin. 2004; 42(4):29-43. PMID: 15577698.
    View in: PubMed
  66. Vidal Melo MF, Barazanji K, Winga E, Johnson RL. Estimate of pulmonary diffusing capacity for oxygen during exercise in humans from routine O(2) and CO(2) measurements. Clin Physiol Funct Imaging. 2004 Jan; 24(1):46-57. PMID: 14717748.
    View in: PubMed
  67. Vidal Melo MF, Layfield D, Harris RS, O'Neill K, Musch G, Richter T, Winkler T, Fischman AJ, Venegas JG. Quantification of regional ventilation-perfusion ratios with PET. J Nucl Med. 2003 Dec; 44(12):1982-91. PMID: 14660725.
    View in: PubMed
  68. O'Neill K, Venegas JG, Richter T, Harris RS, Layfield JD, Musch G, Winkler T, Melo MF. Modeling kinetics of infused 13NN-saline in acute lung injury. J Appl Physiol (1985). 2003 Dec; 95(6):2471-84. PMID: 12897030.
    View in: PubMed
  69. Musch G, Layfield JD, Harris RS, Melo MF, Winkler T, Callahan RJ, Fischman AJ, Venegas JG. Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. J Appl Physiol (1985). 2002 Nov; 93(5):1841-51. PMID: 12381773.
    View in: PubMed
  70. Vidal Melo MF, Harris RS, Layfield D, Musch G, Venegas JG. Changes in regional ventilation after autologous blood clot pulmonary embolism. Anesthesiology. 2002 Sep; 97(3):671-81. PMID: 12218535.
    View in: PubMed
  71. Gamma de Abreu M, Melo MF, Giannella-Neto A. Pulmonary capillary blood flow by partial CO2 rebreathing: importance of the regularity of the respiratory pattern. Clin Physiol. 2000 Sep; 20(5):388-98. PMID: 10971551.
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  72. Vidal Melo MF. Effect of cardiac output on pulmonary gas exchange: role of diffusion limitation with VA/Q mismatch. Respir Physiol. 1998 Jul; 113(1):23-32. PMID: 9776547.
    View in: PubMed
  73. Giannella-Neto A, Bellido C, Barbosa RB, Melo MF. Design and calibration of unicapillary pneumotachographs. J Appl Physiol (1985). 1998 Jan; 84(1):335-43. PMID: 9451654.
    View in: PubMed
  74. Pedrosa RC, Melo MF, Saad EA. [Anaerobic threshold detected using "V-slope analysis" in chronic chagasic disease]. Rev Soc Bras Med Trop. 1997 Mar-Apr; 30(2):129-38. PMID: 9148336.
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  75. Bottino DA, Giannella-Neto A, David CM, Melo MF. Decision support system to assist mechanical ventilation in the adult respiratory distress syndrome. Int J Clin Monit Comput. 1997; 14(2):73-81. PMID: 9336731.
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  76. Scalon JD, Melo MF, Panerai RB. A method for predicting the utilization of medical technology in neonatal care. Technol Health Care. 1996 Mar; 3(4):273-8. PMID: 8705402.
    View in: PubMed
  77. Vidal Melo MF, Loeppky JA, Caprihan A, Luft UC. Alveolar ventilation to perfusion heterogeneity and diffusion impairment in a mathematical model of gas exchange. Comput Biomed Res. 1993 Apr; 26(2):103-20. PMID: 8477584.
    View in: PubMed
  78. Vidal-Melo MF, Schosser R, Barcelos CS, Zwissler B, Messmer K. Heterogeneity of left ventricular perfusion during pulmonary edema and microembolism treated with positive end-expiratory pressure and norepinephrine. Braz J Med Biol Res. 1993; 26(1):37-42. PMID: 8220266.
    View in: PubMed
  79. Vidal Melo MF, Caprihan A, Luft UC, Loeppky JA. Distribution of ventilation and diffusion with perfusion in a two-compartment model of gas exchange. Adv Exp Med Biol. 1990; 277:653-64. PMID: 2128995.
    View in: PubMed
  80. Melo MF, Giannella Neto A. Automatisation of the single-breath nitrogen washout test. Med Biol Eng Comput. 1989 Mar; 27(2):137-46. PMID: 2601432.
    View in: PubMed
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