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Marcos Francisco Vidal Melo, PH.D., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. UG3HL140177 (VIDAL MELO, MARCOS F) Mar 19, 2019 - Feb 29, 2020
    NIH/NHLBI
    1/2: An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
    Role: Principal Investigator
  2. R34HL123438 (VIDAL MELO, MARCOS F) Jul 15, 2015 - Mar 31, 2018
    NIH/NHLBI
    Intraoperative Protective Ventilation and Postoperative Pulmonary Complications
    Role: Principal Investigator
  3. R01HL121228 (VIDAL MELO, MARCOS F) Jan 1, 2014 - Apr 30, 2024
    NIH/NHLBI
    PET/CT-Guided Personalized Mechanical Ventilation to Minimize Ventilator-Induced Lung Injury
    Role: Principal Investigator
  4. R01HL086827 (VIDAL MELO, MARCOS F) Jan 10, 2007 - Dec 31, 2013
    NIH/NHLBI
    PET Imaging of Local Inflammation and Function in Ventilator Induced Lung Injury
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Williams EC, Motta-Ribeiro GC, Vidal Melo MF. Driving Pressure and Transpulmonary Pressure: How Do We Guide Safe Mechanical Ventilation? Anesthesiology. 2019 Jul; 131(1):155-163. PMID: 31094753.
    Citations:    
  2. Kiss T, Bluth T, Braune A, Huhle R, Denz A, Herzog M, Herold J, Vivona L, Millone M, Bergamaschi A, Andreeff M, Scharffenberg M, Wittenstein J, Vidal Melo MF, Koch T, Rocco PRM, Pelosi P, Kotzerke J, Gama de Abreu M. Effects of Positive End-Expiratory Pressure and Spontaneous Breathing Activity on Regional Lung Inflammation in Experimental Acute Respiratory Distress Syndrome. Crit Care Med. 2019 Apr; 47(4):e358-e365. PMID: 30676338.
    Citations:    Fields:    
  3. Szabari MV, Takahashi K, Feng Y, Locascio JJ, Chao W, Carter EA, Vidal Melo MF, Musch G. Relation between Respiratory Mechanics, Inflammation, and Survival in Experimental Mechanical Ventilation. Am J Respir Cell Mol Biol. 2019 Feb; 60(2):179-188. PMID: 30199644.
    Citations:    Fields:    
  4. Motta-Ribeiro GC, Hashimoto S, Winkler T, Baron RM, Grogg K, Paula LFSC, Santos A, Zeng C, Hibbert K, Harris RS, Bajwa E, Vidal Melo MF. Deterioration of Regional Lung Strain and Inflammation during Early Lung Injury. Am J Respir Crit Care Med. 2018 Oct 01; 198(7):891-902. PMID: 29787304.
    Citations:    Fields:    
  5. Fernandez-Bustamante A, Vidal Melo MF. Bedside assessment of lung aeration and stretch. Br J Anaesth. 2018 11; 121(5):1001-1004. PMID: 30336843.
    Citations:    Fields:    
  6. Neto AS, da Costa LGV, Hemmes SNT, Canet J, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Pearse R, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Pelosi P, Schultz MJ. The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study. Eur J Anaesthesiol. 2018 09; 35(9):691-701. PMID: 29916860.
    Citations:    Fields:    
  7. Serpa Neto A, Bos LD, Campos PPZA, Hemmes SNT, Bluth T, Calfee CS, Ferner M, Güldner A, Hollmann MW, India I, Kiss T, Laufenberg-Feldmann R, Sprung J, Sulemanji D, Unzueta C, Vidal Melo MF, Weingarten TN, Tuip-de Boer AM, Pelosi P, Gama de Abreu M, Schultz MJ. Association between pre-operative biological phenotypes and postoperative pulmonary complications: An unbiased cluster analysis. Eur J Anaesthesiol. 2018 09; 35(9):702-709. PMID: 29957706.
    Citations:    Fields:    
  8. Queiroz VNF, da Costa LGV, Barbosa RP, Takaoka F, De Baerdemaeker L, Cesar DS, D'Orto UC, Galdi JR, Gottumukkala V, Cata JP, Hemmes SNT, Hollman MW, Kalmar A, Moura LAB, Mariano RM, Matot I, Mazzinari G, Mills GH, Posso IP, Teruya A, Vidal Melo MF, Sprung J, Weingarten TN, Treschan TA, Koopman S, Eidelman L, Chen LL, Lee JW, Ariño Irujo JJ, Tena B, Groeben H, Pelosi P, de Abreu MG, Schultz MJ, Serpa Neto A. International multicenter observational study on assessment of ventilatory management during general anaesthesia for robotic surgery and its effects on postoperative pulmonary complication (AVATaR): study protocol and statistical analysis plan. BMJ Open. 2018 Aug 23; 8(8):e021643. PMID: 30139899.
    Citations:    Fields:    
  9. Motta-Ribeiro G, Winkler T, Hashimoto S, Vidal Melo MF. Spatial Heterogeneity of Lung Strain and Aeration and Regional Inflammation During Early Lung Injury Assessed with PET/CT. Acad Radiol. 2019 Mar; 26(3):313-325. PMID: 30057194.
    Citations:    Fields:    
  10. Ball L, Hemmes SNT, Serpa Neto A, Bluth T, Canet J, Hiesmayr M, Hollmann MW, Mills GH, Vidal Melo MF, Putensen C, Schmid W, Severgnini P, Wrigge H, Gama de Abreu M, Schultz MJ, Pelosi P. Intraoperative ventilation settings and their associations with postoperative pulmonary complications in obese patients. Br J Anaesth. 2018 Oct; 121(4):899-908. PMID: 30236252.
    Citations:    Fields:    Translation:Humans
  11. Bagchi A, Vidal Melo MF. Follow the Voxel-A New Method for the Analysis of Regional Strain in Lung Injury. Crit Care Med. 2018 Jun; 46(6):1033-1035. PMID: 29762413.
    Citations:    Fields:    
  12. Morais CCA, Koyama Y, Yoshida T, Plens GM, Gomes S, Lima CAS, Ramos OPS, Pereira SM, Kawaguchi N, Yamamoto H, Uchiyama A, Borges JB, Vidal Melo MF, Tucci MR, Amato MBP, Kavanagh BP, Costa ELV, Fujino Y. High Positive End-Expiratory Pressure Renders Spontaneous Effort Noninjurious. Am J Respir Crit Care Med. 2018 May 15; 197(10):1285-1296. PMID: 29323536.
    Citations: 2     Fields:    
  13. Simonis FD, Barbas CSV, Artigas-Raventós A, Canet J, Determann RM, Anstey J, Hedenstierna G, Hemmes SNT, Hermans G, Hiesmayr M, Hollmann MW, Jaber S, Martin-Loeches I, Mills GH, Pearse RM, Putensen C, Schmid W, Severgnini P, Smith R, Treschan TA, Tschernko EM, Vidal Melo MF, Wrigge H, de Abreu MG, Pelosi P, Schultz MJ, Neto AS. Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT. Ann Intensive Care. 2018 Mar 21; 8(1):39. PMID: 29564726.
    Citations: 1     
  14. Ladha KS, Bateman BT, Houle TT, De Jong MAC, Vidal Melo MF, Huybrechts KF, Kurth T, Eikermann M. Variability in the Use of Protective Mechanical Ventilation During General Anesthesia. Anesth Analg. 2018 02; 126(2):503-512. PMID: 28763357.
    Citations:    Fields:    Translation:Humans
  15. D'Antini D, Huhle R, Herrmann J, Sulemanji DS, Oto J, Raimondo P, Mirabella L, Hemmes SNT, Schultz MJ, Pelosi P, Kaczka DW, Vidal Melo MF, Gama de Abreu M, Cinnella G. Respiratory System Mechanics During Low Versus High Positive End-Expiratory Pressure in Open Abdominal Surgery: A Substudy of PROVHILO Randomized Controlled Trial. Anesth Analg. 2018 01; 126(1):143-149. PMID: 28632529.
    Citations: 2     Fields:    Translation:Humans
  16. Dalia AA, Cronin B, Stone ME, Turner K, Hargrave J, Vidal Melo MF, Essandoh M. Anesthetic Management of Patients With Continuous-Flow Left Ventricular Assist Devices Undergoing Noncardiac Surgery: An Update for Anesthesiologists. J Cardiothorac Vasc Anesth. 2018 04; 32(2):1001-1012. PMID: 29306620.
    Citations:    Fields:    Translation:Humans
  17. Fernandez-Bustamante A, Schoen J, Vidal Melo MF. Incentive Spirometry After Bariatric Surgery: The Importance of Patient Compliance. JAMA Surg. 2017 10 01; 152(10):984-985. PMID: 28636722.
    Citations:    Fields:    
  18. Bagchi A, Rudolph MI, Ng PY, Timm FP, Long DR, Shaefi S, Ladha K, Vidal Melo MF, Eikermann M. The association of postoperative pulmonary complications in 109,360 patients with pressure-controlled or volume-controlled ventilation. Anaesthesia. 2017 Nov; 72(11):1334-1343. PMID: 28891046.
    Citations: 2     Fields:    
  19. Fernandez-Bustamante A, Vidal Melo MF. The Increasing Call for Protective Ventilation During Anesthesia-Reply. JAMA Surg. 2017 09 01; 152(9):894. PMID: 28593302.
    Citations:    Fields:    
  20. Staehr-Rye AK, Meyhoff CS, Scheffenbichler FT, Vidal Melo MF, Gätke MR, Walsh JL, Ladha KS, Grabitz SD, Nikolov MI, Kurth T, Rasmussen LS, Eikermann M. High intraoperative inspiratory oxygen fraction and risk of major respiratory complications. Br J Anaesth. 2017 Jul 01; 119(1):140-149. PMID: 28974067.
    Citations:    
  21. Bluth T, Teichmann R, Kiss T, Bobek I, Canet J, Cinnella G, De Baerdemaeker L, Gregoretti C, Hedenstierna G, Hemmes SN, Hiesmayr M, Hollmann MW, Jaber S, Laffey JG, Licker MJ, Markstaller K, Matot I, Müller G, Mills GH, Mulier JP, Putensen C, Rossaint R, Schmitt J, Senturk M, Neto AS, Severgnini P, Sprung J, Vidal Melo MF, Wrigge H, Schultz MJ, Pelosi P, Gama de Abreu M. Erratum to Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial. Trials. 2017 06 01; 18(1):247. PMID: 28571581.
    Citations:    Fields:    
  22. Bluth T, Teichmann R, Kiss T, Bobek I, Canet J, Cinnella G, De Baerdemaeker L, Gregoretti C, Hedenstierna G, Hemmes SN, Hiesmayr M, Hollmann MW, Jaber S, Laffey JG, Licker MJ, Markstaller K, Matot I, Müller G, Mills GH, Mulier JP, Putensen C, Rossaint R, Schmitt J, Senturk M, Serpa Neto A, Severgnini P, Sprung J, Vidal Melo MF, Wrigge H, Schultz MJ, Pelosi P, Gama de Abreu M. Protective intraoperative ventilation with higher versus lower levels of positive end-expiratory pressure in obese patients (PROBESE): study protocol for a randomized controlled trial. Trials. 2017 04 28; 18(1):202. PMID: 28454590.
    Citations: 5     Fields:    Translation:Humans
  23. Güldner A, Braune A, Ball L, Leme Silva P, Samary C, Insorsi A, Huhle R, Rentzsch I, Becker C, Oehme L, Andreeff M, Vidal Melo MF, Winkler T, Pelosi P, Rieken Macedo Rocco P, Kotzerke J, Gama de Abreu M. The authors reply. Crit Care Med. 2017 03; 45(3):e328-e329. PMID: 28212230.
    Citations: 2     Fields:    
  24. Fernandez-Bustamante A, Frendl G, Sprung J, Kor DJ, Subramaniam B, Martinez Ruiz R, Lee JW, Henderson WG, Moss A, Mehdiratta N, Colwell MM, Bartels K, Kolodzie K, Giquel J, Vidal Melo MF. Postoperative Pulmonary Complications, Early Mortality, and Hospital Stay Following Noncardiothoracic Surgery: A Multicenter Study by the Perioperative Research Network Investigators. JAMA Surg. 2017 02 01; 152(2):157-166. PMID: 27829093.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  25. Wellman TJ, de Prost N, Tucci M, Winkler T, Baron RM, Filipczak P, Raby B, Chu JH, Harris RS, Musch G, Dos Reis Falcao LF, Capelozzi V, Venegas JG, Vidal Melo MF. Lung Metabolic Activation as an Early Biomarker of Acute Respiratory Distress Syndrome and Local Gene Expression Heterogeneity. Anesthesiology. 2016 11; 125(5):992-1004. PMID: 27611185.
    Citations: 2     Fields:    Translation:Animals
  26. Güldner A, Braune A, Ball L, Silva PL, Samary C, Insorsi A, Huhle R, Rentzsch I, Becker C, Oehme L, Andreeff M, Vidal Melo MF, Winkler T, Pelosi P, Rocco PR, Kotzerke J, Gama de Abreu M. Comparative Effects of Volutrauma and Atelectrauma on Lung Inflammation in Experimental Acute Respiratory Distress Syndrome. Crit Care Med. 2016 09; 44(9):e854-65. PMID: 27035236.
    Citations: 14     Fields:    Translation:Animals
  27. de Jong MAC, Ladha KS, Vidal Melo MF, Staehr-Rye AK, Bittner EA, Kurth T, Eikermann M. Differential Effects of Intraoperative Positive End-expiratory Pressure (PEEP) on Respiratory Outcome in Major Abdominal Surgery Versus Craniotomy. Ann Surg. 2016 Aug; 264(2):362-369. PMID: 26496082.
    Citations: 8     Fields:    Translation:Humans
  28. Paula LF, Wellman TJ, Winkler T, Spieth PM, Güldner A, Venegas JG, Gama de Abreu M, Carvalho AR, Vidal Melo MF. Regional tidal lung strain in mechanically ventilated normal lungs. J Appl Physiol (1985). 2016 12 01; 121(6):1335-1347. PMID: 27445302.
    Citations: 4     Fields:    Translation:Animals
  29. Freitas CR, Malbouisson LM, Benicio A, Negri EM, Bini FM, Massoco CO, Otsuki DA, Melo MF, Carmona MJ. Lung Perfusion and Ventilation During Cardiopulmonary Bypass Reduces Early Structural Damage to Pulmonary Parenchyma. Anesth Analg. 2016 Apr; 122(4):943-52. PMID: 26991612.
    Citations: 2     Fields:    Translation:Animals
  30. Ladha K, Vidal Melo MF, McLean DJ, Wanderer JP, Grabitz SD, Kurth T, Eikermann M. Intraoperative protective mechanical ventilation and risk of postoperative respiratory complications: hospital based registry study. BMJ. 2015 Jul 14; 351:h3646. PMID: 26174419.
    Citations: 39     Fields:    Translation:Humans
  31. Fernandez-Bustamante A, Hashimoto S, Serpa Neto A, Moine P, Vidal Melo MF, Repine JE. Perioperative lung protective ventilation in obese patients. BMC Anesthesiol. 2015 May 06; 15:56. PMID: 25907273.
    Citations: 9     Fields:    Translation:HumansAnimals
  32. Wellman TJ, Winkler T, Vidal Melo MF. Modeling of Tracer Transport Delays for Improved Quantification of Regional Pulmonary ¹8F-FDG Kinetics, Vascular Transit Times, and Perfusion. Ann Biomed Eng. 2015 Nov; 43(11):2722-34. PMID: 25940652.
    Citations:    Fields:    Translation:Animals
  33. Wiener-Kronish JP, Vidal Melo MF. New investigations of core competencies: perioperative mechanical ventilation and assessment of lung function. Anesthesiology. 2015 Apr; 122(4):723-4. PMID: 25668412.
    Citations:    Fields:    Translation:Humans
  34. Wanderer JP, Ehrenfeld JM, Epstein RH, Kor DJ, Bartz RR, Fernandez-Bustamante A, Vidal Melo MF, Blum JM. Temporal trends and current practice patterns for intraoperative ventilation at U.S. academic medical centers: a retrospective study. BMC Anesthesiol. 2015; 15:40. PMID: 25852301.
    Citations: 8     Fields:    Translation:Humans
  35. de Prost N, Feng Y, Wellman T, Tucci MR, Costa EL, Musch G, Winkler T, Harris RS, Venegas JG, Chao W, Vidal Melo MF. 18F-FDG kinetics parameters depend on the mechanism of injury in early experimental acute respiratory distress syndrome. J Nucl Med. 2014 Nov; 55(11):1871-7. PMID: 25286924.
    Citations: 11     Fields:    Translation:AnimalsCells
  36. Costa EL, Vidal Melo MF. Diaphragmatic electrical activity: a new tool to assess lung hyperinflation? Anesthesiology. 2014 Sep; 121(3):447-9. PMID: 25046571.
    Citations:    Fields:    Translation:Humans
  37. Badgaiyan RD, Weise S, Wack DS, Vidal Melo MF. Attenuation of regional cerebral blood flow during memory processing after coronary artery bypass surgery. Anesth Analg. 2014 Sep; 119(3):550-3. PMID: 24977634.
    Citations: 1     Fields:    Translation:Humans
  38. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Zheng H, Venegas JG, Vidal Melo MF. Effect of local tidal lung strain on inflammation in normal and lipopolysaccharide-exposed sheep*. Crit Care Med. 2014 Jul; 42(7):e491-500. PMID: 24758890.
    Citations: 19     Fields:    Translation:Animals
  39. Musch G, Winkler T, Harris RS, Vidal Melo MF, Wellman TJ, de Prost N, Kradin RL, Venegas JG. Lung [(18)F]fluorodeoxyglucose uptake and ventilation-perfusion mismatch in the early stage of experimental acute smoke inhalation. Anesthesiology. 2014 Mar; 120(3):683-93. PMID: 24051392.
    Citations: 4     Fields:    Translation:Animals
  40. Eikermann M, Vidal Melo MF. Therapeutic range of spontaneous breathing during mechanical ventilation. Anesthesiology. 2014 Mar; 120(3):536-9. PMID: 24424072.
    Citations: 1     Fields:    Translation:Animals
  41. de Prost N, Costa EL, Wellman T, Musch G, Tucci MR, Winkler T, Harris R, Venegas JG, Kavanagh BP, Vidal Melo MF. Effects of ventilation strategy on distribution of lung inflammatory cell activity. Crit Care. 2013 Aug 15; 17(4):R175. PMID: 23947920.
    Citations: 16     Fields:    Translation:AnimalsCells
  42. Kang S, Singh J, Vidal Melo M, Gulur P. Spinal cord stimulation for intercostal neuralgia in a patient with implantable cardiac defibrillator and biventricular pacing. Neuromodulation. 2014 Jun; 17(4):386-8. PMID: 23837496.
    Citations:    Fields:    Translation:Humans
  43. Saha D, Takahashi K, de Prost N, Winkler T, Pinilla-Vera M, Baron RM, Vidal Melo MF. Micro-autoradiographic assessment of cell types contributing to 2-deoxy-2-[(18)F]fluoro-D-glucose uptake during ventilator-induced and endotoxemic lung injury. Mol Imaging Biol. 2013 Feb; 15(1):19-27. PMID: 22752654.
    Citations: 16     Fields:    Translation:AnimalsCells
  44. Harris RS, Fujii-Rios H, Winkler T, Musch G, Vidal Melo MF, Venegas JG. Ventilation defect formation in healthy and asthma subjects is determined by lung inflation. PLoS One. 2012; 7(12):e53216. PMID: 23285270.
    Citations: 8     Fields:    Translation:Humans
  45. Dittrich AS, Winkler T, Wellman T, de Prost N, Musch G, Harris RS, Vidal Melo MF. Modeling 18F-FDG kinetics during acute lung injury: experimental data and estimation errors. PLoS One. 2012; 7(10):e47588. PMID: 23118881.
    Citations: 8     Fields:    Translation:HumansAnimals
  46. Vidal Melo MF, Musch G, Kaczka DW. Pulmonary pathophysiology and lung mechanics in anesthesiology: a case-based overview. Anesthesiol Clin. 2012 Dec; 30(4):759-84. PMID: 23089508.
    Citations: 1     Fields:    Translation:Humans
  47. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, Vidal Melo MF. Effect of regional lung inflation on ventilation heterogeneity at different length scales during mechanical ventilation of normal sheep lungs. J Appl Physiol (1985). 2012 Sep; 113(6):947-57. PMID: 22678958.
    Citations: 17     Fields:    Translation:Animals
  48. Harris RS, Venegas JG, Wongviriyawong C, Winkler T, Kone M, Musch G, Vidal Melo MF, de Prost N, Hamilos DL, Afshar R, Cho J, Luster AD, Medoff BD. 18F-FDG uptake rate is a biomarker of eosinophilic inflammation and airway response in asthma. J Nucl Med. 2011 Nov; 52(11):1713-20. PMID: 21990575.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  49. Takahashi K, Saha D, Shattino I, Pavlov VI, Stahl GL, Finnegan P, Melo MF. Complement 3 is involved with ventilator-induced lung injury. Int Immunopharmacol. 2011 Dec; 11(12):2138-43. PMID: 21979496.
    Citations: 5     Fields:    Translation:AnimalsCells
  50. Carvalho AR, Ichinose F, Schettino IA, Hess D, Rojas J, Giannella-Neto A, Agnihotri A, Walker J, MacGillivray TE, Vidal Melo MF. Tidal lung recruitment and exhaled nitric oxide during coronary artery bypass grafting in patients with and without chronic obstructive pulmonary disease. Lung. 2011 Dec; 189(6):499-509. PMID: 21952833.
    Citations: 2     Fields:    Translation:Humans
  51. de Prost N, Costa EL, Wellman T, Musch G, Winkler T, Tucci MR, Harris RS, Venegas JG, Vidal Melo MF. Effects of surfactant depletion on regional pulmonary metabolic activity during mechanical ventilation. J Appl Physiol (1985). 2011 Nov; 111(5):1249-58. PMID: 21799132.
    Citations: 15     Fields:    Translation:Animals
  52. de Prost N, El-Karak C, Avila M, Ichinose F, Vidal Melo MF. Changes in cysteinyl leukotrienes during and after cardiac surgery with cardiopulmonary bypass in patients with and without chronic obstructive pulmonary disease. J Thorac Cardiovasc Surg. 2011 Jun; 141(6):1496-502.e3. PMID: 21377695.
    Citations: 4     Fields:    Translation:Humans
  53. Schroeder T, Melo MF, Venegas JG. Analysis of 2-[Fluorine-18]-Fluoro-2-deoxy-D-glucose uptake kinetics in PET studies of pulmonary inflammation. Acad Radiol. 2011 Apr; 18(4):418-23. PMID: 21292507.
    Citations: 5     Fields:    Translation:Humans
  54. Ficke DJ, Lee J, Chaney MA, Bas H, Vidal-Melo MF, Stone ME. Case 6-2010: Noncardiac surgery in patients with a left ventricular assist device. J Cardiothorac Vasc Anesth. 2010 Dec; 24(6):1002-9. PMID: 21109156.
    Citations: 4     Fields:    Translation:Humans
  55. de Prost N, Tucci MR, Melo MF. Assessment of lung inflammation with 18F-FDG PET during acute lung injury. AJR Am J Roentgenol. 2010 Aug; 195(2):292-300. PMID: 20651183.
    Citations: 24     Fields:    Translation:Humans
  56. Wellman TJ, Winkler T, Costa EL, Musch G, Harris RS, Venegas JG, Melo MF. Measurement of regional specific lung volume change using respiratory-gated PET of inhaled 13N-nitrogen. J Nucl Med. 2010 Apr; 51(4):646-53. PMID: 20237036.
    Citations: 14     Fields:    Translation:Animals
  57. Costa EL, Musch G, Winkler T, Schroeder T, Harris RS, Jones HA, Venegas JG, Vidal Melo MF. Mild endotoxemia during mechanical ventilation produces spatially heterogeneous pulmonary neutrophilic inflammation in sheep. Anesthesiology. 2010 Mar; 112(3):658-69. PMID: 20179503.
    Citations: 27     Fields:    Translation:AnimalsCells
  58. Vidal Melo MF, Winkler T, Harris RS, Musch G, Greene RE, Venegas JG. Spatial heterogeneity of lung perfusion assessed with (13)N PET as a vascular biomarker in chronic obstructive pulmonary disease. J Nucl Med. 2010 Jan; 51(1):57-65. PMID: 20008987.
    Citations: 20     Fields:    Translation:Humans
  59. Costa EL, Vidal Melo MF. Lung water: what you see (with computed tomography) and what you get (with a bedside device). Anesthesiology. 2009 Nov; 111(5):933-5. PMID: 19858867.
    Citations: 2     Fields:    Translation:HumansAnimals
  60. Harris RS, Winkler T, Musch G, Vidal Melo MF, Schroeder T, Tgavalekos N, Venegas JG. The prone position results in smaller ventilation defects during bronchoconstriction in asthma. J Appl Physiol (1985). 2009 Jul; 107(1):266-74. PMID: 19443742.
    Citations: 12     Fields:    Translation:Humans
  61. Carvalho AR, Spieth PM, Pelosi P, Vidal Melo MF, Koch T, Jandre FC, Giannella-Neto A, de Abreu MG. Ability of dynamic airway pressure curve profile and elastance for positive end-expiratory pressure titration. Intensive Care Med. 2008 Dec; 34(12):2291-9. PMID: 18825365.
    Citations: 26     Fields:    Translation:Animals
  62. Melo MF, Leone BJ. Introduction of new monitors into clinical anesthesia. Anesth Analg. 2008 Sep; 107(3):749-50. PMID: 18713878.
    Citations:    Fields:    Translation:HumansPHPublic Health
  63. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Modeling pulmonary kinetics of 2-deoxy-2-[18F]fluoro-D-glucose during acute lung injury. Acad Radiol. 2008 Jun; 15(6):763-75. PMID: 18486012.
    Citations: 23     Fields:    Translation:Animals
  64. Alexander JH, Emery RW, Carrier M, Ellis SJ, Mehta RH, Hasselblad V, Menasche P, Khalil A, Cote R, Bennett-Guerrero E, Mack MJ, Schuler G, Harrington RA, Tardif JC. Efficacy and safety of pyridoxal 5'-phosphate (MC-1) in high-risk patients undergoing coronary artery bypass graft surgery: the MEND-CABG II randomized clinical trial. JAMA. 2008 Apr 16; 299(15):1777-87. PMID: 18381567.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  65. Loeppky JA, Icenogle MV, Charlton GA, Conn CA, Maes D, Riboni K, Gates L, Melo MF, Roach RC. Hypoxemia and acute mountain sickness: which comes first? High Alt Med Biol. 2008; 9(4):271-9. PMID: 19115910.
    Citations: 7     Fields:    Translation:HumansPHPublic Health
  66. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Venegas JG, Winkler T. Image-derived input function for assessment of 18F-FDG uptake by the inflamed lung. J Nucl Med. 2007 Nov; 48(11):1889-96. PMID: 17942803.
    Citations: 16     Fields:    Translation:HumansAnimals
  67. Musch G, Bellani G, Vidal Melo MF, Harris RS, Winkler T, Schroeder T, Venegas JG. Relation between shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2008 Feb 01; 177(3):292-300. PMID: 17932380.
    Citations: 15     Fields:    Translation:Animals
  68. Chumnanvej S, Wood MJ, MacGillivray TE, Melo MF. Perioperative echocardiographic examination for ventricular assist device implantation. Anesth Analg. 2007 Sep; 105(3):583-601. PMID: 17717209.
    Citations: 16     Fields:    Translation:Humans
  69. Musch G, Venegas JG, Bellani G, Winkler T, Schroeder T, Petersen B, Harris RS, Melo MF. Regional gas exchange and cellular metabolic activity in ventilator-induced lung injury. Anesthesiology. 2007 Apr; 106(4):723-35. PMID: 17413910.
    Citations: 36     Fields:    Translation:Animals
  70. Tgavalekos NT, Musch G, Harris RS, Vidal Melo MF, Winkler T, Schroeder T, Callahan R, Lutchen KR, Venegas JG. Relationship between airway narrowing, patchy ventilation and lung mechanics in asthmatics. Eur Respir J. 2007 Jun; 29(6):1174-81. PMID: 17360726.
    Citations: 24     Fields:    Translation:Humans
  71. Schroeder T, Vidal Melo MF, Musch G, Harris RS, Winkler T, Venegas JG. PET imaging of regional 18F-FDG uptake and lung function after cigarette smoke inhalation. J Nucl Med. 2007 Mar; 48(3):413-9. PMID: 17332619.
    Citations: 16     Fields:    Translation:AnimalsPHPublic Health
  72. Loeppky JA, Icenogle MV, Caprihan A, Vidal Melo MF, Altobelli SA. CO2 rebreathing model in COPD: blood-to-gas equilibration. Eur J Appl Physiol. 2006 Nov; 98(5):450-60. PMID: 16960726.
    Citations:    Fields:    Translation:Humans
  73. Harris RS, Winkler T, Tgavalekos N, Musch G, Melo MF, Schroeder T, Chang Y, Venegas JG. Regional pulmonary perfusion, inflation, and ventilation defects in bronchoconstricted patients with asthma. Am J Respir Crit Care Med. 2006 Aug 01; 174(3):245-53. PMID: 16690973.
    Citations: 34     Fields:    Translation:Humans
  74. Venegas JG, Schroeder T, Harris S, Winkler RT, Melo MF. The distribution of ventilation during bronchoconstriction is patchy and bimodal: a PET imaging study. Respir Physiol Neurobiol. 2005 Aug 25; 148(1-2):57-64. PMID: 15994134.
    Citations: 28     Fields:    Translation:Animals
  75. Tgavalekos NT, Tawhai M, Harris RS, Musch G, Mush G, Vidal-Melo M, Venegas JG, Lutchen KR. Identifying airways responsible for heterogeneous ventilation and mechanical dysfunction in asthma: an image functional modeling approach. J Appl Physiol (1985). 2005 Dec; 99(6):2388-97. PMID: 16081622.
    Citations: 42     Fields:    Translation:HumansCTClinical Trials
  76. Loeppky JA, Caprihan A, Altobelli SA, Icenogle MV, Scotto P, Vidal Melo MF. Validation of a two-compartment model of ventilation/perfusion distribution. Respir Physiol Neurobiol. 2006 Mar 28; 151(1):74-92. PMID: 16024300.
    Citations: 4     Fields:    Translation:HumansAnimals
  77. Richter T, Bellani G, Scott Harris R, Vidal Melo MF, Winkler T, Venegas JG, Musch G. Effect of prone position on regional shunt, aeration, and perfusion in experimental acute lung injury. Am J Respir Crit Care Med. 2005 Aug 15; 172(4):480-7. PMID: 15901611.
    Citations: 31     Fields:    Translation:Animals
  78. Shaff DA, Raines DE, Vidal Melo MF, King ME, Misra S, Chen LL. Anesthetic management for transurethral resection of the bladder in a 74-year-old man with uncorrected tetralogy of Fallot. J Clin Anesth. 2005 May; 17(3):198-201. PMID: 15896587.
    Citations:    Fields:    Translation:Humans
  79. Venegas JG, Winkler T, Musch G, Vidal Melo MF, Layfield D, Tgavalekos N, Fischman AJ, Callahan RJ, Bellani G, Harris RS. Self-organized patchiness in asthma as a prelude to catastrophic shifts. Nature. 2005 Apr 07; 434(7034):777-82. PMID: 15772676.
    Citations: 115     Fields:    Translation:Humans
  80. Melo MF, Harris RS, Layfield JD, Venegas JG. Topographic basis of bimodal ventilation-perfusion distributions during bronchoconstriction in sheep. Am J Respir Crit Care Med. 2005 Apr 01; 171(7):714-21. PMID: 15640360.
    Citations: 11     Fields:    Translation:Animals
  81. Musch G, Harris RS, Vidal Melo MF, O'Neill KR, Layfield JD, Winkler T, Venegas JG. Mechanism by which a sustained inflation can worsen oxygenation in acute lung injury. Anesthesiology. 2004 Feb; 100(2):323-30. PMID: 14739807.
    Citations: 26     Fields:    Translation:Animals
  82. Vidal Melo MF. Clinical respiratory physiology of the neonate and infant with congenital heart disease. Int Anesthesiol Clin. 2004; 42(4):29-43. PMID: 15577698.
    Citations: 1     Fields:    Translation:Humans
  83. Vidal Melo MF, Barazanji K, Winga E, Johnson RL. Estimate of pulmonary diffusing capacity for oxygen during exercise in humans from routine O(2) and CO(2) measurements. Clin Physiol Funct Imaging. 2004 Jan; 24(1):46-57. PMID: 14717748.
    Citations:    Fields:    Translation:HumansCellsCTClinical Trials
  84. Vidal Melo MF, Layfield D, Harris RS, O'Neill K, Musch G, Richter T, Winkler T, Fischman AJ, Venegas JG. Quantification of regional ventilation-perfusion ratios with PET. J Nucl Med. 2003 Dec; 44(12):1982-91. PMID: 14660725.
    Citations: 41     Fields:    Translation:Animals
  85. O'Neill K, Venegas JG, Richter T, Harris RS, Layfield JD, Musch G, Winkler T, Melo MF. Modeling kinetics of infused 13NN-saline in acute lung injury. J Appl Physiol (1985). 2003 Dec; 95(6):2471-84. PMID: 12897030.
    Citations: 14     Fields:    Translation:Animals
  86. Musch G, Layfield JD, Harris RS, Melo MF, Winkler T, Callahan RJ, Fischman AJ, Venegas JG. Topographical distribution of pulmonary perfusion and ventilation, assessed by PET in supine and prone humans. J Appl Physiol (1985). 2002 Nov; 93(5):1841-51. PMID: 12381773.
    Citations: 54     Fields:    Translation:Humans
  87. Vidal Melo MF, Harris RS, Layfield D, Musch G, Venegas JG. Changes in regional ventilation after autologous blood clot pulmonary embolism. Anesthesiology. 2002 Sep; 97(3):671-81. PMID: 12218535.
    Citations: 20     Fields:    Translation:Animals
  88. Gamma de Abreu M, Melo MF, Giannella-Neto A. Pulmonary capillary blood flow by partial CO2 rebreathing: importance of the regularity of the respiratory pattern. Clin Physiol. 2000 Sep; 20(5):388-98. PMID: 10971551.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  89. Vidal Melo MF. Effect of cardiac output on pulmonary gas exchange: role of diffusion limitation with VA/Q mismatch. Respir Physiol. 1998 Jul; 113(1):23-32. PMID: 9776547.
    Citations: 3     Fields:    
  90. Giannella-Neto A, Bellido C, Barbosa RB, Melo MF. Design and calibration of unicapillary pneumotachographs. J Appl Physiol (1985). 1998 Jan; 84(1):335-43. PMID: 9451654.
    Citations: 3     Fields:    Translation:Animals
  91. Pedrosa RC, Melo MF, Saad EA. [Anaerobic threshold detected using "V-slope analysis" in chronic chagasic disease]. Rev Soc Bras Med Trop. 1997 Mar-Apr; 30(2):129-38. PMID: 9148336.
    Citations:    Fields:    Translation:Humans
  92. Bottino DA, Giannella-Neto A, David CM, Melo MF. Decision support system to assist mechanical ventilation in the adult respiratory distress syndrome. Int J Clin Monit Comput. 1997; 14(2):73-81. PMID: 9336731.
    Citations:    Fields:    Translation:Humans
  93. Scalon JD, Melo MF, Panerai RB. A method for predicting the utilization of medical technology in neonatal care. Technol Health Care. 1996 Mar; 3(4):273-8. PMID: 8705402.
    Citations:    Fields:    Translation:Humans
  94. Vidal Melo MF, Loeppky JA, Caprihan A, Luft UC. Alveolar ventilation to perfusion heterogeneity and diffusion impairment in a mathematical model of gas exchange. Comput Biomed Res. 1993 Apr; 26(2):103-20. PMID: 8477584.
    Citations: 3     Fields:    Translation:HumansCells
  95. Vidal-Melo MF, Schosser R, Barcelos CS, Zwissler B, Messmer K. Heterogeneity of left ventricular perfusion during pulmonary edema and microembolism treated with positive end-expiratory pressure and norepinephrine. Braz J Med Biol Res. 1993; 26(1):37-42. PMID: 8220266.
    Citations:    Fields:    Translation:Animals
  96. Vidal Melo MF, Caprihan A, Luft UC, Loeppky JA. Distribution of ventilation and diffusion with perfusion in a two-compartment model of gas exchange. Adv Exp Med Biol. 1990; 277:653-64. PMID: 2128995.
    Citations:    Fields:    Translation:Humans
  97. Melo MF, Giannella Neto A. Automatisation of the single-breath nitrogen washout test. Med Biol Eng Comput. 1989 Mar; 27(2):137-46. PMID: 2601432.
    Citations:    Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.