Malcolm Russell Whitman, Ph.D.
Concepts
This page shows the publications Malcolm Whitman has written about Piperidines.
Connection Strength
0.592
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Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nat Chem Biol. 2012 Feb 12; 8(3):311-7.
Score: 0.259
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Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proc Natl Acad Sci U S A. 2020 04 21; 117(16):8900-8911.
Score: 0.114
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Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model. J Heart Lung Transplant. 2016 Apr; 35(4):518-27.
Score: 0.084
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The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20; 7(288):288ra77.
Score: 0.081
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Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science. 2009 Jun 05; 324(5932):1334-8.
Score: 0.054
Connection Strength
The connection strength for concepts is the sum of the scores for each matching publication.
Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.