Harvard Catalyst Profiles

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Malcolm Russell Whitman, Ph.D.

Concepts

This page shows the publications Malcolm Whitman has written about Animals.
Connection Strength

0.209
  1. A secreted tyrosine kinase acts in the extracellular environment. Cell. 2014 Aug 28; 158(5):1033-1044.
    View in: PubMed
    Score: 0.014
  2. A mutation in TGFB3 associated with a syndrome of low muscle mass, growth retardation, distal arthrogryposis and clinical features overlapping with Marfan and Loeys-Dietz syndrome. Am J Med Genet A. 2013 Aug; 161A(8):2040-6.
    View in: PubMed
    Score: 0.013
  3. Regarding the mechanism of action of a proposed peptide agonist of the bone morphogenetic protein receptor activin-like kinase 3. Nat Med. 2013 Jul; 19(7):809-10.
    View in: PubMed
    Score: 0.013
  4. Halofuginone and other febrifugine derivatives inhibit prolyl-tRNA synthetase. Nat Chem Biol. 2012 Feb 12; 8(3):311-7.
    View in: PubMed
    Score: 0.012
  5. The role and regulation of GDF11 in Smad2 activation during tailbud formation in the Xenopus embryo. Mech Dev. 2010 Sep-Dec; 127(9-12):485-95.
    View in: PubMed
    Score: 0.011
  6. Oxidative stress drives disulfide bond formation between basic helix-loop-helix transcription factors. J Cell Biochem. 2010 Feb 01; 109(2):417-24.
    View in: PubMed
    Score: 0.011
  7. TRIQK, a novel family of small proteins localized to the endoplasmic reticulum membrane, is conserved across vertebrates. Zoolog Sci. 2008 Jul; 25(7):706-13.
    View in: PubMed
    Score: 0.009
  8. Identification of a novel pool of extracellular pro-myostatin in skeletal muscle. J Biol Chem. 2008 Mar 14; 283(11):7027-35.
    View in: PubMed
    Score: 0.009
  9. TGF-beta signaling is required for multiple processes during Xenopus tail regeneration. Dev Biol. 2008 Mar 01; 315(1):203-16.
    View in: PubMed
    Score: 0.009
  10. Inhibitor-resistant type I receptors reveal specific requirements for TGF-beta signaling in vivo. Dev Biol. 2006 Jul 15; 295(2):730-42.
    View in: PubMed
    Score: 0.008
  11. A Serpin family gene, protease nexin-1 has an activity distinct from protease inhibition in early Xenopus embryos. Mech Dev. 2006 Jun; 123(6):463-71.
    View in: PubMed
    Score: 0.008
  12. XCR2, one of three Xenopus EGF-CFC genes, has a distinct role in the regulation of left-right patterning. Development. 2006 Jan; 133(2):237-50.
    View in: PubMed
    Score: 0.008
  13. TGFbeta signaling at the summit. Development. 2005 Oct; 132(19):4205-10.
    View in: PubMed
    Score: 0.008
  14. Conditional BMP inhibition in Xenopus reveals stage-specific roles for BMPs in neural and neural crest induction. Dev Biol. 2005 Jan 15; 277(2):425-42.
    View in: PubMed
    Score: 0.007
  15. p53 and TGF-beta in development: prelude to tumor suppression? Cell. 2003 May 02; 113(3):275-6.
    View in: PubMed
    Score: 0.007
  16. Endogenous patterns of BMP signaling during early chick development. Dev Biol. 2002 Apr 01; 244(1):44-65.
    View in: PubMed
    Score: 0.006
  17. The secreted tyrosine kinase VLK is essential for normal platelet activation and thrombus formation. Blood. 2022 01 06; 139(1):104-117.
    View in: PubMed
    Score: 0.006
  18. Nodal signaling in early vertebrate embryos: themes and variations. Dev Cell. 2001 Nov; 1(5):605-17.
    View in: PubMed
    Score: 0.006
  19. Nodal signals to Smads through Cripto-dependent and Cripto-independent mechanisms. Mol Cell. 2001 May; 7(5):949-57.
    View in: PubMed
    Score: 0.006
  20. Aminoacyl-tRNA synthetase inhibition activates a pathway that branches from the canonical amino acid response in mammalian cells. Proc Natl Acad Sci U S A. 2020 04 21; 117(16):8900-8911.
    View in: PubMed
    Score: 0.005
  21. Smads and early developmental signaling by the TGFbeta superfamily. Genes Dev. 1998 Aug 15; 12(16):2445-62.
    View in: PubMed
    Score: 0.005
  22. Smad4 and FAST-1 in the assembly of activin-responsive factor. Nature. 1997 Sep 04; 389(6646):85-9.
    View in: PubMed
    Score: 0.004
  23. A transcriptional partner for MAD proteins in TGF-beta signalling. Nature. 1996 Oct 24; 383(6602):691-6.
    View in: PubMed
    Score: 0.004
  24. Halofuginone treatment reduces interleukin-17A and ameliorates features of chronic lung allograft dysfunction in a mouse orthotopic lung transplant model. J Heart Lung Transplant. 2016 Apr; 35(4):518-27.
    View in: PubMed
    Score: 0.004
  25. The cytoplasmic prolyl-tRNA synthetase of the malaria parasite is a dual-stage target of febrifugine and its analogs. Sci Transl Med. 2015 May 20; 7(288):288ra77.
    View in: PubMed
    Score: 0.004
  26. Halofuginone inhibits TH17 cell differentiation by activating the amino acid starvation response. Science. 2009 Jun 05; 324(5932):1334-8.
    View in: PubMed
    Score: 0.003
  27. Xnr2 and Xnr5 unprocessed proteins inhibit Wnt signaling upstream of dishevelled. Dev Dyn. 2005 Dec; 234(4):900-10.
    View in: PubMed
    Score: 0.002
  28. New roles for FoxH1 in patterning the early embryo. Development. 2004 Oct; 131(20):5065-78.
    View in: PubMed
    Score: 0.002
  29. Mixer/Bon and FoxH1/Sur have overlapping and divergent roles in Nodal signaling and mesendoderm induction. Development. 2003 Dec; 130(23):5589-99.
    View in: PubMed
    Score: 0.002
  30. Regulation of the Lim-1 gene is mediated through conserved FAST-1/FoxH1 sites in the first intron. Dev Dyn. 2002 Dec; 225(4):448-56.
    View in: PubMed
    Score: 0.002
  31. Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning. Genes Dev. 2002 Nov 01; 16(21):2749-54.
    View in: PubMed
    Score: 0.002
Connection Strength

The connection strength for concepts is the sum of the scores for each matching publication.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.

Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.