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Brian Adair, Ph.D.

Co-Author

This page shows the publications co-authored by Brian Adair and M. Arnaout.
Connection Strength

2.572
  1. Adair BD, Alonso JL, van Agthoven J, Hayes V, Ahn HS, Yu IS, Lin SW, Xiong JP, Poncz M, Arnaout MA. Structure-guided design of pure orthosteric inhibitors of aIIbß3 that prevent thrombosis but preserve hemostasis. Nat Commun. 2020 01 21; 11(1):398.
    View in: PubMed
    Score: 0.970
  2. Adair BD, Xiong JP, Alonso JL, Hyman BT, Arnaout MA. EM structure of the ectodomain of integrin CD11b/CD18 and localization of its ligand-binding site relative to the plasma membrane. PLoS One. 2013; 8(2):e57951.
    View in: PubMed
    Score: 0.602
  3. Van Agthoven JF, Shams H, Cochran FV, Alonso JL, Kintzing JR, Garakani K, Adair BD, Xiong JP, Mofrad MRK, Cochran JR, Arnaout MA. Structural Basis of the Differential Binding of Engineered Knottins to Integrins aVß3 and a5ß1. Structure. 2019 09 03; 27(9):1443-1451.e6.
    View in: PubMed
    Score: 0.234
  4. Mahalingam B, Van Agthoven JF, Xiong JP, Alonso JL, Adair BD, Rui X, Anand S, Mehrbod M, Mofrad MR, Burger C, Goodman SL, Arnaout MA. Atomic basis for the species-specific inhibition of aV integrins by monoclonal antibody 17E6 is revealed by the crystal structure of aVß3 ectodomain-17E6 Fab complex. J Biol Chem. 2014 May 16; 289(20):13801-9.
    View in: PubMed
    Score: 0.162
  5. Van Agthoven JF, Xiong JP, Alonso JL, Rui X, Adair BD, Goodman SL, Arnaout MA. Structural basis for pure antagonism of integrin aVß3 by a high-affinity form of fibronectin. Nat Struct Mol Biol. 2014 Apr; 21(4):383-8.
    View in: PubMed
    Score: 0.162
  6. Adair BD, Altintas MM, Möller CC, Arnaout MA, Reiser J. Structure of the kidney slit diaphragm adapter protein CD2-associated protein as determined with electron microscopy. J Am Soc Nephrol. 2014 Jul; 25(7):1465-73.
    View in: PubMed
    Score: 0.161
  7. Mahalingam B, Ajroud K, Alonso JL, Anand S, Adair BD, Horenstein AL, Malavasi F, Xiong JP, Arnaout MA. Stable coordination of the inhibitory Ca2+ ion at the metal ion-dependent adhesion site in integrin CD11b/CD18 by an antibody-derived ligand aspartate: implications for integrin regulation and structure-based drug design. J Immunol. 2011 Dec 15; 187(12):6393-401.
    View in: PubMed
    Score: 0.138
  8. Adair BD, Xiong JP, Maddock C, Goodman SL, Arnaout MA, Yeager M. Three-dimensional EM structure of the ectodomain of integrin {alpha}V{beta}3 in a complex with fibronectin. J Cell Biol. 2005 Mar 28; 168(7):1109-18.
    View in: PubMed
    Score: 0.087
  9. Wei C, Li J, Adair BD, Zhu K, Cai J, Merchant M, Samelko B, Liao Z, Koh KH, Tardi NJ, Dande RR, Liu S, Ma J, Dibartolo S, Hägele S, Peev V, Hayek SS, Cimbaluk DJ, Tracy M, Klein J, Sever S, Shattil SJ, Arnaout MA, Reiser J. uPAR isoform 2 forms a dimer and induces severe kidney disease in mice. J Clin Invest. 2019 04 02; 129(5):1946-1959.
    View in: PubMed
    Score: 0.057
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.