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Olivia Marion Farr, Ph.D.


Wellesley College, Wellesley, MABA05/2008Neuroscience, Psychology
Yale University, New Haven, CTMPhil05/2011Neuroscience
Yale University, New Haven, CTPhD03/2013Neuroscience

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Tuccinardi D, Farr OM, Upadhyay J, Oussaada SM, Mathew H, Paschou SA, Perakakis N, Koniaris A, Kelesidis T, Mantzoros CS. Lorcaserin treatment decreases body weight and reduces cardiometabolic risk factors in obese adults: A six-month, randomized, placebo-controlled, double-blind clinical trial. Diabetes Obes Metab. 2019 Feb 06. PMID: 30724455.
  2. Papathanasiou AE, Nolen-Doerr E, Farr OM, Mantzoros CS. GEOFFREY HARRIS PRIZE LECTURE 2018: Novel pathways regulating neuroendocrine function, energy homeostasis and metabolism in humans. Eur J Endocrinol. 2019 Feb 01; 180(2):R59-R71. PMID: 30475221.
    Citations:    Fields:    
  3. Peradze N, Farr OM, Mantzoros CS. Research developments in metabolism 2018. Metabolism. 2019 Feb; 91:70-79. PMID: 30503805.
    Citations:    Fields:    
  4. Pilitsi E, Farr OM, Polyzos SA, Perakakis N, Nolen-Doerr E, Papathanasiou AE, Mantzoros CS. Pharmacotherapy of obesity: Available medications and drugs under investigation. Metabolism. 2019 Mar; 92:170-192. PMID: 30391259.
    Citations:    Fields:    
  5. Farr OM, Mantzoros CS. Obese individuals with type 2 diabetes demonstrate decreased activation of the salience-related insula and increased activation of the emotion/salience-related amygdala to visual food cues compared to non-obese individuals with diabetes: A preliminary study. Diabetes Obes Metab. 2018 10; 20(10):2500-2503. PMID: 29882627.
    Citations:    Fields:    Translation:Humans
  6. Farr OM, Mantzoros CS. Advances at the intersection of sleep and metabolism research. Metabolism. 2018 07; 84:1-2. PMID: 29634954.
    Citations:    Fields:    
  7. Upadhyay J, Farr O, Perakakis N, Ghaly W, Mantzoros C. Obesity as a Disease. Med Clin North Am. 2018 Jan; 102(1):13-33. PMID: 29156181.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  8. Seo JA, Kang MC, Ciaraldi TP, Kim SS, Park KS, Choe C, Hwang WM, Lim DM, Farr O, Mantzoros C, Henry RR, Kim YB. Circulating ApoJ is closely associated with insulin resistance in human subjects. Metabolism. 2018 01; 78:155-166. PMID: 28986164.
    Citations:    Fields:    Translation:Humans
  9. Farr OM, Tuccinardi D, Upadhyay J, Oussaada SM, Mantzoros CS. Walnut consumption increases activation of the insula to highly desirable food cues: A randomized, double-blind, placebo-controlled, cross-over fMRI study. Diabetes Obes Metab. 2018 01; 20(1):173-177. PMID: 28715141.
    Citations: 2     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  10. Farr OM, Rifas-Shiman SL, Oken E, Taveras EM, Mantzoros CS. Current child, but not maternal, snoring is bi-directionally related to adiposity and cardiometabolic risk markers: A cross-sectional and a prospective cohort analysis. Metabolism. 2017 11; 76:70-80. PMID: 28774733.
    Citations:    Fields:    Translation:Humans
  11. Farr OM, Mantzoros CS. Treating prediabetes in the obese: are GLP-1 analogues the answer? Lancet. 2017 04 08; 389(10077):1371-1372. PMID: 28237265.
    Citations:    Fields:    Translation:Humans
  12. Farr OM, Mantzoros CS. Sleep apnea in relation to metabolism: An urgent need to study underlying mechanisms and to develop novel treatments for this unmet clinical need. Metabolism. 2017 04; 69:207-210. PMID: 28190524.
    Citations: 1     Fields:    Translation:Humans
  13. Farr OM, Mantzoros CS. Treatment options to prevent diabetes in subjects with prediabetes: Efficacy, cost effectiveness and future outlook. Metabolism. 2017 05; 70:192-195. PMID: 28095990.
    Citations:    Fields:    Translation:Humans
  14. Farr OM, Mantzoros CS. Obese individuals with more components of the metabolic syndrome and/or prediabetes demonstrate decreased activation of reward-related brain centers in response to food cues in both the fed and fasting states: a preliminary fMRI study. Int J Obes (Lond). 2017 03; 41(3):471-474. PMID: 28017966.
    Citations: 1     Fields:    Translation:Humans
  15. Perakakis N, Farr OM, Tuccinardi D, Upadhyay J, Mantzoros CS. Research advances in metabolism 2016. Metabolism. 2017 02; 67:41-53. PMID: 28081777.
    Citations:    Fields:    Translation:HumansAnimals
  16. Farr OM, Upadhyay J, Gavrieli A, Camp M, Spyrou N, Kaye H, Mathew H, Vamvini M, Koniaris A, Kilim H, Srnka A, Migdal A, Mantzoros CS. Lorcaserin Administration Decreases Activation of Brain Centers in Response to Food Cues and These Emotion- and Salience-Related Changes Correlate With Weight Loss Effects: A 4-Week-Long Randomized, Placebo-Controlled, Double-Blind Clinical Trial. Diabetes. 2016 10; 65(10):2943-53. PMID: 27385157; PMCID: PMC5033259.
    Citations: 7     Fields:    Translation:Humans
  17. Kline RL, Zhang S, Farr OM, Hu S, Zaborszky L, Samanez-Larkin GR, Li CS. The Effects of Methylphenidate on Resting-State Functional Connectivity of the Basal Nucleus of Meynert, Locus Coeruleus, and Ventral Tegmental Area in Healthy Adults. Front Hum Neurosci. 2016; 10:149. PMID: 27148006; PMCID: PMC4834346.
    Citations: 7     
  18. Farr OM, Tsoukas MA, Triantafyllou G, Dincer F, Filippaios A, Ko BJ, Mantzoros CS. Short-term administration of the GLP-1 analog liraglutide decreases circulating leptin and increases GIP levels and these changes are associated with alterations in CNS responses to food cues: A randomized, placebo-controlled, crossover study. Metabolism. 2016 Jul; 65(7):945-53. PMID: 27282865; PMCID: PMC4902873.
    Citations: 7     Fields:    Translation:Humans
  19. Vamvini MT, Hamnvik OP, Sahin-Efe A, Gavrieli A, Dincer F, Farr OM, Mantzoros CS. Differential Effects of Oral and Intravenous Lipid Administration on Key Molecules Related to Energy Homeostasis. J Clin Endocrinol Metab. 2016 05; 101(5):1989-97. PMID: 26964729.
    Citations:    Fields:    Translation:Humans
  20. Farr OM, Li CS, Mantzoros CS. Central nervous system regulation of eating: Insights from human brain imaging. Metabolism. 2016 May; 65(5):699-713. PMID: 27085777.
    Citations: 9     Fields:    Translation:HumansCells
  21. Farr OM, Sofopoulos M, Tsoukas MA, Dincer F, Thakkar B, Sahin-Efe A, Filippaios A, Bowers J, Srnka A, Gavrieli A, Ko BJ, Liakou C, Kanyuch N, Tseleni-Balafouta S, Mantzoros CS. GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue liraglutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial. Diabetologia. 2016 05; 59(5):954-65. PMID: 26831302; PMCID: PMC4826792.
    Citations: 11     Fields:    Translation:Humans
  22. Manza P, Hu S, Ide JS, Farr OM, Zhang S, Leung HC, Li CS. The effects of methylphenidate on cerebral responses to conflict anticipation and unsigned prediction error in a stop-signal task. J Psychopharmacol. 2016 Mar; 30(3):283-93. PMID: 26755547.
    Citations: 3     Fields:    Translation:Humans
  23. Mathew H, Farr OM, Mantzoros CS. Metabolic health and weight: Understanding metabolically unhealthy normal weight or metabolically healthy obese patients. Metabolism. 2016 Jan; 65(1):73-80. PMID: 26683798; PMCID: PMC4750380.
    Citations: 13     Fields:    Translation:HumansAnimals
  24. Farr OM, Gavrieli A, Mantzoros CS. Leptin applications in 2015: what have we learned about leptin and obesity? Curr Opin Endocrinol Diabetes Obes. 2015 Oct; 22(5):353-9. PMID: 26313897; PMCID: PMC4610373.
    Citations: 8     Fields:    Translation:HumansAnimals
  25. Gavrieli A, Farr OM, Davis CR, Crowell JA, Mantzoros CS. Early life adversity and/or posttraumatic stress disorder severity are associated with poor diet quality, including consumption of trans fatty acids, and fewer hours of resting or sleeping in a US middle-aged population: A cross-sectional and prospective study. Metabolism. 2015 Nov; 64(11):1597-610. PMID: 26404481; PMCID: PMC4609606.
    Citations: 8     Fields:    Translation:Humans
  26. Farr OM, Ko BJ, Joung KE, Zaichenko L, Usher N, Tsoukas M, Thakkar B, Davis CR, Crowell JA, Mantzoros CS. Posttraumatic stress disorder, alone or additively with early life adversity, is associated with obesity and cardiometabolic risk. Nutr Metab Cardiovasc Dis. 2015 May; 25(5):479-88. PMID: 25770759; PMCID: PMC4404181.
    Citations: 12     Fields:    Translation:Humans
  27. Farr OM, Camp M, Mantzoros CS. New research developments and insights from Metabolism. Metabolism. 2015 Mar; 64(3):354-67. PMID: 25549908; PMCID: PMC4459594.
    Citations: 1     Fields:    Translation:HumansAnimals
  28. Farr OM, Fiorenza C, Papageorgiou P, Brinkoetter M, Ziemke F, Koo BB, Rojas R, Mantzoros CS. Leptin therapy alters appetite and neural responses to food stimuli in brain areas of leptin-sensitive subjects without altering brain structure. J Clin Endocrinol Metab. 2014 Dec; 99(12):E2529-38. PMID: 25279500; PMCID: PMC4255115.
    Citations: 8     Fields:    Translation:Humans
  29. Upadhyay J, Farr OM, Mantzoros CS. The role of leptin in regulating bone metabolism. Metabolism. 2015 Jan; 64(1):105-13. PMID: 25497343; PMCID: PMC4532332.
    Citations: 25     Fields:    Translation:HumansAnimals
  30. Stieg MR, Sievers C, Farr O, Stalla GK, Mantzoros CS. Leptin: A hormone linking activation of neuroendocrine axes with neuropathology. Psychoneuroendocrinology. 2015 Jan; 51:47-57. PMID: 25290346.
    Citations: 10     Fields:    Translation:Humans
  31. Farr OM, Sloan DM, Keane TM, Mantzoros CS. Stress- and PTSD-associated obesity and metabolic dysfunction: a growing problem requiring further research and novel treatments. Metabolism. 2014 Dec; 63(12):1463-8. PMID: 25267015; PMCID: PMC4459590.
    Citations: 6     Fields:    Translation:Humans
  32. Tsoukas MA, Farr OM, Mantzoros CS. Leptin in congenital and HIV-associated lipodystrophy. Metabolism. 2015 Jan; 64(1):47-59. PMID: 25267014.
    Citations: 9     Fields:    Translation:HumansAnimals
  33. Farr OM, Tsoukas MA, Mantzoros CS. Leptin and the brain: influences on brain development, cognitive functioning and psychiatric disorders. Metabolism. 2015 Jan; 64(1):114-30. PMID: 25092133.
    Citations: 15     Fields:    Translation:HumansAnimals
  34. Farr OM, Zhang S, Hu S, Matuskey D, Abdelghany O, Malison RT, Li CS. The effects of methylphenidate on resting-state striatal, thalamic and global functional connectivity in healthy adults. Int J Neuropsychopharmacol. 2014 Aug; 17(8):1177-91. PMID: 24825078; PMCID: PMC4506752.
    Citations: 12     Fields:    Translation:Humans
  35. Farr OM, Hu S, Matuskey D, Zhang S, Abdelghany O, Li CS. The effects of methylphenidate on cerebral activations to salient stimuli in healthy adults. Exp Clin Psychopharmacol. 2014 Apr; 22(2):154-65. PMID: 24188171.
    Citations: 10     Fields:    Translation:Humans
  36. Tsoukas MA, Farr OM, Mantzoros CS. Advances in metabolism. Metabolism. 2013 Dec; 62(12):1700-13. PMID: 24112391.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  37. Zhang S, Hu S, Chao HH, Ide JS, Luo X, Farr OM, Li CS. Ventromedial prefrontal cortex and the regulation of physiological arousal. Soc Cogn Affect Neurosci. 2014 Jul; 9(7):900-8. PMID: 23620600; PMCID: PMC4090954.
    Citations: 19     Fields:    Translation:Humans
  38. Luo X, Zhang S, Hu S, Bednarski SR, Erdman E, Farr OM, Hong KI, Sinha R, Mazure CM, Li CS. Error processing and gender-shared and -specific neural predictors of relapse in cocaine dependence. Brain. 2013 Apr; 136(Pt 4):1231-44. PMID: 23485852.
    Citations: 37     Fields:    Translation:HumansCellsPHPublic Health
  39. Ide JS, Zhang S, Hu S, Matuskey D, Bednarski SR, Erdman E, Farr OM, Li CS. Gray matter volume correlates of global positive alcohol expectancy in non-dependent adult drinkers. Addict Biol. 2014 Sep; 19(5):895-906. PMID: 23461484.
    Citations: 6     Fields:    Translation:Humans
  40. Farr OM, Hu S, Zhang S, Li CS. Decreased saliency processing as a neural measure of Barratt impulsivity in healthy adults. Neuroimage. 2012 Nov 15; 63(3):1070-7. PMID: 22885245.
    Citations: 23     Fields:    Translation:Humans
  41. Zhang S, Hu S, Chao HH, Luo X, Farr OM, Li CS. Cerebral correlates of skin conductance responses in a cognitive task. Neuroimage. 2012 Sep; 62(3):1489-98. PMID: 22634217; PMCID: PMC3408848.
    Citations: 16     Fields:    Translation:Humans
  42. Hendrick OM, Luo X, Zhang S, Li CS. Saliency processing and obesity: a preliminary imaging study of the stop signal task. Obesity (Silver Spring). 2012 Sep; 20(9):1796-802. PMID: 21720427; PMCID: PMC3653271.
    Citations: 27     Fields:    Translation:Humans
  43. Hendrick OM, Ide JS, Luo X, Li CS. Dissociable processes of cognitive control during error and non-error conflicts: a study of the stop signal task. PLoS One. 2010 Oct 06; 5(10):e13155. PMID: 20949134; PMCID: PMC2950843.
    Citations: 32     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.