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Lifei Hou, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yuki K, Mitsui Y, Shibamura-Fujiogi M, Hou L, Odegard KC, Soriano SG, Priebe GP, Koutsogiannaki S. Anesthetics isoflurane and sevoflurane attenuate flagellin-mediated inflammation in the lung. Biochem Biophys Res Commun. 2021 06 11; 557:254-260. PMID: 33894411.
    Citations:    Fields:    Translation:HumansAnimalsCells
  2. Shibamura-Fujiogi M, Yuki K, Hou L. Cathepsin L regulates pathogenicCD4 T cells in experimental autoimmune encephalomyelitis. Int Immunopharmacol. 2021 Apr; 93:107425. PMID: 33540247.
    Citations:    Fields:    Translation:HumansAnimalsCells
  3. Shibamura-Fujiogi M, Koutsogiannaki S, Hou L, Yuki K. The Microbial Flora in an Experimental Polymicrobial Abdominal Sepsis Model Probed by 16S rRNA Sequencing. Transl Perioper Pain Med. 2021; 8(1):305-311. PMID: 33521166.
  4. Hou L, Voit RA, Sankaran VG, Springer TA, Yuki K. CD11c regulates hematopoietic stem and progenitor cells under stress. Blood Adv. 2020 12 22; 4(24):6086-6097. PMID: 33351105.
    Citations:    Fields:    Translation:AnimalsCells
  5. Yuki K, Hou L, Shibamura-Fujiogi M, Koutsogiannaki S, Soriano SG. Mechanistic consideration of the effect of perioperative volatile anesthetics on phagocytes. Clin Immunol. 2021 01; 222:108635. PMID: 33217544.
    Citations: 2     Fields:    Translation:HumansCells
  6. Koutsogiannaki S, Bu W, Hou L, Shibamura-Fujiogi M, Ishida H, Ohto U, Eckenhoff RG, Yuki K. The effect of anesthetics on toll like receptor 9. FASEB J. 2020 11; 34(11):14645-14654. PMID: 32901993.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Mitsui Y, Hou L, Huang X, Odegard KC, Pereira LM, Yuki K. Volatile Anesthetic Sevoflurane Attenuates Toll-Like Receptor 1/2 Activation. Anesth Analg. 2020 08; 131(2):631-639. PMID: 32149756.
    Citations: 7     Fields:    Translation:HumansCells
  8. Hou L, Yuki K. SerpinB1 expression in Th17 cells depends on hypoxia-inducible factor 1-alpha. Int Immunopharmacol. 2020 Oct; 87:106826. PMID: 32717567.
    Citations: 1     Fields:    Translation:AnimalsCells
  9. Yuki K, Hou L. Role of ß2 Integrins in Neutrophils and Sepsis. Infect Immun. 2020 05 20; 88(6). PMID: 32205406.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  10. Okuno T, Koutsogiannaki S, Hou L, Bu W, Ohto U, Eckenhoff RG, Yokomizo T, Yuki K. Volatile anesthetics isoflurane and sevoflurane directly target and attenuate Toll-like receptor 4 system. FASEB J. 2019 12; 33(12):14528-14541. PMID: 31675483.
    Citations: 10     Fields:    Translation:AnimalsCells
  11. Hou L, Rao DA, Yuki K, Cooley J, Henderson LA, Jonsson AH, Kaiserman D, Gorman MP, Nigrovic PA, Bird PI, Becher B, Remold-O'Donnell E. SerpinB1 controls encephalitogenic T helper cells in neuroinflammation. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20635-20643. PMID: 31548399.
    Citations: 4     Fields:    Translation:AnimalsCells
  12. Koutsogiannaki S, Hou L, Babazada H, Okuno T, Blazon-Brown N, Soriano SG, Yokomizo T, Yuki K. The volatile anesthetic sevoflurane reduces neutrophil apoptosis via Fas death domain-Fas-associated death domain interaction. FASEB J. 2019 11; 33(11):12668-12679. PMID: 31513427.
    Citations: 5     Fields:    Translation:AnimalsCells
  13. Zha H, Matsunami E, Blazon-Brown N, Koutsogiannaki S, Hou L, Bu W, Babazada H, Odegard KC, Liu R, Eckenhoff RG, Yuki K. Volatile anesthetics affect macrophage phagocytosis. PLoS One. 2019; 14(5):e0216163. PMID: 31071106.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  14. Cao YJ, Xu Y, Liu B, Zheng X, Wu J, Zhang Y, Li XS, Qi Y, Sun YM, Wen WB, Hou L, Wan CP. Dioscin, a Steroidal Saponin Isolated from Dioscorea nipponica, Attenuates Collagen-Induced Arthritis by Inhibiting Th17 Cell Response. Am J Chin Med. 2019; 47(2):423-437. PMID: 30827153.
    Citations: 1     Fields:    Translation:AnimalsCells
  15. Wang CZ, Hou L, Wan JY, Yao H, Yuan J, Zeng J, Park CW, Kim SH, Seo DB, Shin KS, Zhang CF, Chen L, Zhang QH, Liu Z, Sava-Segal C, Yuan CS. Ginseng berry polysaccharides on inflammation-associated colon cancer: inhibiting T-cell differentiation, promoting apoptosis, and enhancing the effects of 5-fluorouracil. J Ginseng Res. 2020 Mar; 44(2):282-290. PMID: 32148410.
    Citations: 4     
  16. Qi Y, Gao F, Hou L, Wan C. Anti-Inflammatory and Immunostimulatory Activities of Astragalosides. Am J Chin Med. 2017; 45(6):1157-1167. PMID: 28830214.
    Citations: 23     Fields:    Translation:HumansAnimalsCells
  17. Hou L, Huang H. Immune suppressive properties of artemisinin family drugs. Pharmacol Ther. 2016 10; 166:123-7. PMID: 27411673.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  18. El Ouaamari A, Dirice E, Gedeon N, Hu J, Zhou JY, Shirakawa J, Hou L, Goodman J, Karampelias C, Qiang G, Boucher J, Martinez R, Gritsenko MA, De Jesus DF, Kahraman S, Bhatt S, Smith RD, Beer HD, Jungtrakoon P, Gong Y, Goldfine AB, Liew CW, Doria A, Andersson O, Qian WJ, Remold-O'Donnell E, Kulkarni RN. SerpinB1 Promotes Pancreatic ß Cell Proliferation. Cell Metab. 2016 Jan 12; 23(1):194-205. PMID: 26701651.
    Citations: 78     Fields:    Translation:HumansAnimalsCells
  19. Hou L, Cooley J, Swanson R, Ong PC, Pike RN, Bogyo M, Olson ST, Remold-O'Donnell E. The protease cathepsin L regulates Th17 cell differentiation. J Autoimmun. 2015 Dec; 65:56-63. PMID: 26343333.
    Citations: 14     Fields:    Translation:AnimalsCells
  20. Liang Y, Jie Z, Hou L, Yi P, Wang W, Kwota Z, Salvato M, de Waal Malefyt R, Soong L, Sun J. IL-33 promotes innate IFN-? production and modulates dendritic cell response in LCMV-induced hepatitis in mice. Eur J Immunol. 2015 Nov; 45(11):3052-63. PMID: 26249267.
    Citations: 19     Fields:    Translation:AnimalsCells
  21. Shi C, Li H, Yang Y, Hou L. Anti-inflammatory and immunoregulatory functions of artemisinin and its derivatives. Mediators Inflamm. 2015; 2015:435713. PMID: 25960615.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  22. Hou L, Wang T, Sun J. ?d T cells in infection and autoimmunity. Int Immunopharmacol. 2015 Oct; 28(2):887-91. PMID: 25864620.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  23. Hou L, Block KE, Huang H. Artesunate abolishes germinal center B cells and inhibits autoimmune arthritis. PLoS One. 2014; 9(8):e104762. PMID: 25116436.
    Citations: 9     Fields:    Translation:AnimalsCells
  24. Hou L, Jie Z, Liang Y, Desai M, Soong L, Sun J. Type 1 interferon-induced IL-7 maintains CD8+ T-cell responses and homeostasis by suppressing PD-1 expression in viral hepatitis. Cell Mol Immunol. 2015 Mar; 12(2):213-21. PMID: 25027969.
    Citations: 12     Fields:    Translation:AnimalsCells
  25. Jie Z, Liang Y, Hou L, Dong C, Iwakura Y, Soong L, Cong Y, Sun J. Intrahepatic innate lymphoid cells secrete IL-17A and IL-17F that are crucial for T cell priming in viral infection. J Immunol. 2014 Apr 01; 192(7):3289-300. PMID: 24600029.
    Citations: 17     Fields:    Translation:AnimalsCells
  26. Zhao P, Hou L, Farley K, Sundrud MS, Remold-O'Donnell E. SerpinB1 regulates homeostatic expansion of IL-17+ ?d and CD4+ Th17 cells. J Leukoc Biol. 2014 Mar; 95(3):521-30. PMID: 24249741.
    Citations: 9     Fields:    Translation:AnimalsCells
  27. Liang Y, Jie Z, Hou L, Aguilar-Valenzuela R, Vu D, Soong L, Sun J. IL-33 induces nuocytes and modulates liver injury in viral hepatitis. J Immunol. 2013 Jun 01; 190(11):5666-75. PMID: 23630360.
    Citations: 37     Fields:    Translation:AnimalsCells
  28. Wan CP, Gao LX, Hou LF, Yang XQ, He PL, Yang YF, Tang W, Yue JM, Li J, Zuo JP. Astragaloside II triggers T cell activation through regulation of CD45 protein tyrosine phosphatase activity. Acta Pharmacol Sin. 2013 Apr; 34(4):522-30. PMID: 23524573.
    Citations: 16     Fields:    Translation:AnimalsCells
  29. Hou L, Jie Z, Desai M, Liang Y, Soong L, Wang T, Sun J. Early IL-17 production by intrahepatic T cells is important for adaptive immune responses in viral hepatitis. J Immunol. 2013 Jan 15; 190(2):621-9. PMID: 23233727.
    Citations: 26     Fields:    Translation:AnimalsCells
  30. Hou LF, He SJ, Li X, Wan CP, Yang Y, Zhang XH, He PL, Zhou Y, Zhu FH, Yang YF, Li Y, Tang W, Zuo JP. SM934 treated lupus-prone NZB × NZW F1 mice by enhancing macrophage interleukin-10 production and suppressing pathogenic T cell development. PLoS One. 2012; 7(2):e32424. PMID: 22389703.
    Citations: 25     Fields:    Translation:AnimalsCells
  31. Hou LF, He SJ, Li X, Yang Y, He PL, Zhou Y, Zhu FH, Yang YF, Li Y, Tang W, Zuo JP. Oral administration of artemisinin analog SM934 ameliorates lupus syndromes in MRL/lpr mice by inhibiting Th1 and Th17 cell responses. Arthritis Rheum. 2011 Aug; 63(8):2445-55. PMID: 21484768.
    Citations: 44     Fields:    Translation:AnimalsCells
  32. Yan J, Jie Z, Hou L, Wanderley JL, Soong L, Gupta S, Qiu S, Chan T, Sun J. Parenchymal expression of CD40 exacerbates adenovirus-induced hepatitis in mice. Hepatology. 2011 May; 53(5):1455-67. PMID: 21360722.
    Citations: 12     Fields:    Translation:AnimalsCells
  33. Ni J, Zhu YN, Zhong XG, Ding Y, Hou LF, Tong XK, Tang W, Ono S, Yang YF, Zuo JP. The chemokine receptor antagonist, TAK-779, decreased experimental autoimmune encephalomyelitis by reducing inflammatory cell migration into the central nervous system, without affecting T cell function. Br J Pharmacol. 2009 Dec; 158(8):2046-56. PMID: 20050195.
    Citations: 13     Fields:    Translation:AnimalsCells
  34. Wang JX, Hou LF, Yang Y, Tang W, Li Y, Zuo JP. SM905, an artemisinin derivative, inhibited NO and pro-inflammatory cytokine production by suppressing MAPK and NF-kappaB pathways in RAW 264.7 macrophages. Acta Pharmacol Sin. 2009 Oct; 30(10):1428-35. PMID: 19801997.
    Citations: 25     Fields:    Translation:AnimalsCells
  35. Hou LF, He SJ, Wang JX, Yang Y, Zhu FH, Zhou Y, He PL, Zhang Y, Yang YF, Li Y, Tang W, Zuo JP. SM934, a water-soluble derivative of arteminisin, exerts immunosuppressive functions in vitro and in vivo. Int Immunopharmacol. 2009 Dec; 9(13-14):1509-17. PMID: 19772931.
    Citations: 15     Fields:    Translation:AnimalsCellsPHPublic Health
  36. Chen HJ, Wang WL, Wang GF, Shi LP, Gu M, Ren YD, Hou LF, He PL, Zhu FH, Zhong XG, Tang W, Zuo JP, Nan FJ. Rational design and synthesis of 2,2-bisheterocycle tandem derivatives as non-nucleoside hepatitis B virus inhibitors. ChemMedChem. 2008 Sep; 3(9):1316-21. PMID: 18663717.
    Citations: 7     Fields:    Translation:Cells
  37. Wan J, Zhu YN, Feng JQ, Chen HJ, Zhang RJ, Ni J, Chen ZH, Hou LF, Liu QF, Zhang J, Yang L, Tang W, Yang YF, Nan FJ, Zhao WM, Zuo JP. Periplocoside A, a pregnane glycoside from Periploca sepium Bge, prevents concanavalin A-induced mice hepatitis through inhibiting NKT-derived inflammatory cytokine productions. Int Immunopharmacol. 2008 Sep; 8(9):1248-56. PMID: 18602071.
    Citations: 5     Fields:    Translation:AnimalsCells
  38. Wang JX, Tang W, Yang ZS, Wan J, Shi LP, Zhang Y, Zhou R, Ni J, Hou LF, Zhou Y, He PL, Yang YF, Li Y, Zuo JP. Suppressive effect of a novel water-soluble artemisinin derivative SM905 on T cell activation and proliferation in vitro and in vivo. Eur J Pharmacol. 2007 Jun 14; 564(1-3):211-8. PMID: 17349993.
    Citations: 10     Fields:    Translation:AnimalsCells
  39. Hou LF, Dai Y, Xia YF, Gong ZN. Alleviation of picryl chloride-induced delayed type hypersensitivity reaction by saponin fraction of Gleditsia sinensis. Biol Pharm Bull. 2006 May; 29(5):1056-9. PMID: 16651747.
    Citations: 1     Fields:    Translation:AnimalsCells
  40. Dai Y, Hou LF, Chan YP, Cheng L, But PP. Inhibition of immediate allergic reactions by ethanol extract from Plumbago zeylanica stems. Biol Pharm Bull. 2004 Mar; 27(3):429-32. PMID: 14993817.
    Citations: 8     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.