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Michael Miller, M.D.,Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. K08AG065502 (MILLER, MICHAEL B) Mar 1, 2020 - Feb 28, 2025
    Genome-Wide Somatic Mutation in Alzheimer's Disease Pathogenesis Using Single Neuron Analysis
    Role: Principal Investigator
  2. F30NS064637 (MILLER, MICHAEL B) Jan 1, 2009 - Dec 31, 2013
    Role of PrPc Polybasic domains in prion conversion
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Choudhury S, Huang AY, Kim J, Zhou Z, Morillo K, Maury EA, Tsai JW, Miller MB, Lodato MA, Araten S, Hilal N, Lee EA, Chen MH, Walsh CA. Somatic mutations in single human cardiomyocytes reveal age-associated DNA damage and widespread oxidative genotoxicity. Nat Aging. 2022 Aug; 2(8):714-725. PMID: 36051457.
  2. Stern AM, Liu L, Jin S, Liu W, Meunier AL, Ericsson M, Miller MB, Batson M, Sun T, Kathuria S, Reczek D, Pradier L, Selkoe DJ. A calcium-sensitive antibody isolates soluble amyloid-ß aggregates and fibrils from Alzheimer's disease brain. Brain. 2022 07 29; 145(7):2528-2540. PMID: 35084489; PMCID: PMC9337809.
    Citations:    Fields:    
  3. Miller MB, Huang AY, Kim J, Zhou Z, Kirkham SL, Maury EA, Ziegenfuss JS, Reed HC, Neil JE, Rento L, Ryu SC, Ma CC, Luquette LJ, Ames HM, Oakley DH, Frosch MP, Hyman BT, Lodato MA, Lee EA, Walsh CA. Somatic genomic changes in single Alzheimer's disease neurons. Nature. 2022 04; 604(7907):714-722. PMID: 35444284; PMCID: PMC9357465.
    Citations: 1     Fields:    Translation:HumansCells
  4. McGinnis SM, Stern AM, Woods JK, Torre M, Feany MB, Miller MB, Silbersweig DA, Gale SA, Daffner KR. Case Study 1: A 55-Year-Old Woman With Progressive Cognitive, Perceptual, and Motor Impairments. J Neuropsychiatry Clin Neurosci. 2022 Winter; 34(1):8-15. PMID: 34763525; PMCID: PMC8813898.
    Citations:    Fields:    Translation:Humans
  5. Miller MB, Reed HC, Walsh CA. Brain Somatic Mutation in Aging and Alzheimer's Disease. Annu Rev Genomics Hum Genet. 2021 08 31; 22:239-256. PMID: 33979534.
    Citations: 6     Fields:    Translation:HumansCells
  6. Doan RN, Miller MB, Kim SN, Rodin RE, Ganz J, Bizzotto S, Morillo KS, Huang AY, Digumarthy R, Zemmel Z, Walsh CA. MIPP-Seq: ultra-sensitive rapid detection and validation of low-frequency mosaic mutations. BMC Med Genomics. 2021 02 12; 14(1):47. PMID: 33579278.
    Citations: 4     Fields:    Translation:Humans
  7. Shah K, Folpe AL, Miller M, Morgan JA, Raut CP, Doyle LA. Primary intra-abdominal melanoma arising in association with extracutaneous blue naevus: a report of two cases. Histopathology. 2021 Jan; 78(2):281-289. PMID: 32698251.
    Citations:    Fields:    Translation:HumansCells
  8. Kim J, Zhao B, Huang AY, Miller MB, Lodato MA, Walsh CA, Lee EA. APP gene copy number changes reflect exogenous contamination. Nature. 2020 08; 584(7821):E20-E28. PMID: 32814883; PMCID: PMC7704338.
    Citations: 7     Fields:    
  9. Cagney DN, Miller MB, Dubuc A, Delalle I, Ligon AH, Chukwueke U, Al-Mefty O, Aizer A, Ligon K, Wen P. Clinical Importance of CDKN2A Loss and Monosomy 10 in Pilocytic Astrocytoma. Cureus. 2019 May 23; 11(5):e4726. PMID: 31355086; PMCID: PMC6649926.
    Citations: 1     
  10. Giantini Larsen AM, Cote DJ, Zaidi HA, Bi WL, Schmitt PJ, Iorgulescu JB, Miller MB, Smith TR, Lopes MB, Jane JA, Laws ER. Spindle cell oncocytoma of the pituitary gland. J Neurosurg. 2018 10 19; 131(2):517-525. PMID: 30485213; PMCID: PMC6486883.
    Citations: 8     Fields:    Translation:Humans
  11. Berkowitz AL, Miller MB, Mir SA, Cagney D, Chavakula V, Guleria I, Aizer A, Ligon KL, Chi JH. Glioproliferative Lesion of the Spinal Cord as a Complication of "Stem-Cell Tourism". N Engl J Med. 2016 Jul 14; 375(2):196-8. PMID: 27331440.
    Citations: 42     Fields:    Translation:Humans
  12. Miller MB, Bi WL, Ramkissoon LA, Kang YJ, Abedalthagafi M, Knoff DS, Agarwalla PK, Wen PY, Reardon DA, Alexander BM, Laws ER, Dunn IF, Beroukhim R, Ligon KL, Ramkissoon SH. MAPK activation and HRAS mutation identified in pituitary spindle cell oncocytoma. Oncotarget. 2016 Jun 14; 7(24):37054-37063. PMID: 27175596.
    Citations: 12     Fields:    Translation:HumansCells
  13. Tolchin B, Fantaneanu T, Miller M, Helgager J, Lee JW. Status epilepticus caused by cerebral amyloid angiopathy-related inflammation. Epilepsy Behav Case Rep. 2016; 6:19-22. PMID: 27408804; PMCID: PMC4925902.
    Citations: 3     
  14. Farmakiotis D, Liakos A, Miller MB, Krane JF, Baden LR, Hammond SP. An Avid Imitator. J Clin Med Res. 2016 Mar; 8(3):257-9. PMID: 26858802; PMCID: PMC4737040.
  15. Noble GP, Wang DW, Walsh DJ, Barone JR, Miller MB, Nishina KA, Li S, Supattapone S. A Structural and Functional Comparison Between Infectious and Non-Infectious Autocatalytic Recombinant PrP Conformers. PLoS Pathog. 2015 Jun; 11(6):e1005017. PMID: 26125623; PMCID: PMC4488359.
    Citations: 21     Fields:    Translation:AnimalsCells
  16. Sridharan V, Urbanski LM, Bi WL, Thistle K, Miller MB, Ramkissoon S, Reardon DA, Dunn IF. Multicentric Low-Grade Gliomas. World Neurosurg. 2015 Oct; 84(4):1045-50. PMID: 26004698.
    Citations: 3     Fields:    Translation:Humans
  17. Thomas AA, Fisher JL, Rahme GJ, Hampton TH, Baron U, Olek S, Schwachula T, Rhodes CH, Gui J, Tafe LJ, Tsongalis GJ, Lefferts JA, Wishart H, Kleen J, Miller M, Whipple CA, de Abreu FB, Ernstoff MS, Fadul CE. Regulatory T cells are not a strong predictor of survival for patients with glioblastoma. Neuro Oncol. 2015 Jun; 17(6):801-9. PMID: 25618892; PMCID: PMC4483125.
    Citations: 22     Fields:    Translation:HumansCells
  18. Noble GP, Walsh DJ, Miller MB, Jackson WS, Supattapone S. Requirements for mutant and wild-type prion protein misfolding in vitro. Biochemistry. 2015 Feb 10; 54(5):1180-7. PMID: 25584902.
    Citations: 12     Fields:    Translation:AnimalsCells
  19. Miller MB, Wang DW, Wang F, Noble GP, Ma J, Woods VL, Li S, Supattapone S. Cofactor molecules induce structural transformation during infectious prion formation. Structure. 2013 Nov 05; 21(11):2061-8. PMID: 24120764.
    Citations: 42     Fields:    Translation:AnimalsCells
  20. Praitis V, Simske J, Kniss S, Mandt R, Imlay L, Feddersen C, Miller MB, Mushi J, Liszewski W, Weinstein R, Chakravorty A, Ha DG, Schacht Farrell A, Sullivan-Wilson A, Stock T. The secretory pathway calcium ATPase PMR-1/SPCA1 has essential roles in cell migration during Caenorhabditis elegans embryonic development. PLoS Genet. 2013 May; 9(5):e1003506. PMID: 23696750.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  21. Supattapone S and MB Miller. Prions and Diseases: Physiology and Pathophysiology. Chapter 7: Cofactor Involvement in Prion Propagation. 2013; 1:93-105. View Publication.
  22. Turnbaugh JA, Unterberger U, Saá P, Massignan T, Fluharty BR, Bowman FP, Miller MB, Supattapone S, Biasini E, Harris DA. The N-terminal, polybasic region of PrP(C) dictates the efficiency of prion propagation by binding to PrP(Sc). J Neurosci. 2012 Jun 27; 32(26):8817-30. PMID: 22745483.
    Citations: 42     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  23. Miller MB, Geoghegan JC, Supattapone S. Dissociation of infectivity from seeding ability in prions with alternate docking mechanism. PLoS Pathog. 2011 Jul; 7(7):e1002128. PMID: 21779169.
    Citations: 34     Fields:    Translation:AnimalsCells
  24. Miller MB, Supattapone S. Superparamagnetic nanoparticle capture of prions for amplification. J Virol. 2011 Mar; 85(6):2813-7. PMID: 21228242.
    Citations: 9     Fields:    Translation:Animals
  25. Geoghegan JC, Miller MB, Kwak AH, Harris BT, Supattapone S. Trans-dominant inhibition of prion propagation in vitro is not mediated by an accessory cofactor. PLoS Pathog. 2009 Jul; 5(7):e1000535. PMID: 19649330.
    Citations: 38     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.