Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Caroline Heintz, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Bhadra M, Howell P, Dutta S, Heintz C, Mair WB. Alternative splicing in aging and longevity. Hum Genet. 2020 Mar; 139(3):357-369. PMID: 31834493.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  2. Silva-García CG, Lanjuin A, Heintz C, Dutta S, Clark NM, Mair WB. Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans. G3 (Bethesda). 2019 07 09; 9(7):2195-2198. PMID: 31064766.
    Citations: 13     Fields:    Translation:Animals
  3. Silva-García CG, Lanjuin A, Heintz C, Dutta S, Clark NM, Mair WB. Single-Copy Knock-In Loci for Defined Gene Expression in Caenorhabditis elegans. G3 (Bethesda). 2019 Jul 01; 9(7):2195-2198. PMID: 33877345.
    Citations: 1     Fields:    
  4. Heintz C, Doktor TK, Lanjuin A, Escoubas CC, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB. Corrigendum: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans. Nature. 2017 07 27; 547(7664):476. PMID: 28700577.
    Citations: 3     Fields:    
  5. Heintz C, Doktor TK, Lanjuin A, Escoubas C, Zhang Y, Weir HJ, Dutta S, Silva-García CG, Bruun GH, Morantte I, Hoxhaj G, Manning BD, Andresen BS, Mair WB. Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans. Nature. 2017 01 05; 541(7635):102-106. PMID: 27919065; PMCID: PMC5361225.
    Citations: 68     Fields:    Translation:AnimalsCells
  6. Shen N, Heintz C, Thiel C, Okun JG, Hoffmann GF, Blau N. Co-expression of phenylalanine hydroxylase variants and effects of interallelic complementation on in vitro enzyme activity and genotype-phenotype correlation. Mol Genet Metab. 2016 Mar; 117(3):328-35. PMID: 26803807.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  7. Heintz C, Mair W. You are what you host: microbiome modulation of the aging process. Cell. 2014 Jan 30; 156(3):408-11. PMID: 24485451.
    Citations: 96     Fields:    Translation:HumansAnimals
  8. Heintz C, Cotton RG, Blau N. Tetrahydrobiopterin, its mode of action on phenylalanine hydroxylase, and importance of genotypes for pharmacological therapy of phenylketonuria. Hum Mutat. 2013 Jul; 34(7):927-36. PMID: 23559577.
    Citations: 20     Fields:    Translation:Humans
  9. Heintz C, Dobrowolski SF, Andersen HS, Demirkol M, Blau N, Andresen BS. Splicing of phenylalanine hydroxylase (PAH) exon 11 is vulnerable: molecular pathology of mutations in PAH exon 11. Mol Genet Metab. 2012 Aug; 106(4):403-11. PMID: 22698810.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  10. Heintz C, Troxler H, Martinez A, Thöny B, Blau N. Quantification of phenylalanine hydroxylase activity by isotope-dilution liquid chromatography-electrospray ionization tandem mass spectrometry. Mol Genet Metab. 2012 Apr; 105(4):559-65. PMID: 22300847.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  11. Dobrowolski SF, Heintz C, Miller T, Ellingson C, Ellingson C, Ozer I, Gökçay G, Baykal T, Thöny B, Demirkol M, Blau N. Molecular genetics and impact of residual in vitro phenylalanine hydroxylase activity on tetrahydrobiopterin responsiveness in Turkish PKU population. Mol Genet Metab. 2011 Feb; 102(2):116-21. PMID: 21147011.
    Citations: 18     Fields:    Translation:Humans
  12. Karacic I, Meili D, Sarnavka V, Heintz C, Thöny B, Ramadza DP, Fumic K, Mardesic D, Baric I, Blau N. Genotype-predicted tetrahydrobiopterin (BH4)-responsiveness and molecular genetics in Croatian patients with phenylalanine hydroxylase (PAH) deficiency. Mol Genet Metab. 2009 Jul; 97(3):165-71. PMID: 19394257.
    Citations: 30     Fields:    Translation:HumansCTClinical Trials
  13. Buck I, Morceau F, Cristofanon S, Heintz C, Chateauvieux S, Reuter S, Dicato M, Diederich M. Tumor necrosis factor alpha inhibits erythroid differentiation in human erythropoietin-dependent cells involving p38 MAPK pathway, GATA-1 and FOG-1 downregulation and GATA-2 upregulation. Biochem Pharmacol. 2008 Nov 15; 76(10):1229-39. PMID: 18805401.
    Citations: 19     Fields:    Translation:HumansCells
  14. Neuenschwander M, Butz M, Heintz C, Kast P, Hilvert D. A simple selection strategy for evolving highly efficient enzymes. Nat Biotechnol. 2007 Oct; 25(10):1145-7. PMID: 17873865.
    Citations: 19     Fields:    Translation:Cells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: SPH faculty should contact Faculty Affairs at facultyaffairshsph.harvard.edu).
Heintz's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (95)
Explore
_
Co-Authors (4)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
© 2023 President and Fellows of Harvard College
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.