Harvard Catalyst Profiles

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Jeffrey Mito, M.D.,Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Yoon JY, Chapel D, Goebel E, Qian X, Mito J, Horowitz N, Miron A, Soong TR, Xian W, Crum CP. Molecular catastrophe, the peritoneal cavity and ovarian cancer prevention. J Pathol. 2022 Mar 02. PMID: 35238033.
    Citations:    Fields:    
  2. Hanna GJ, ONeill A, Cutler JM, Flynn M, Vijaykumar T, Clark JR, Wirth LJ, Lorch JH, Park JC, Mito JK, Lohr JG, Kaufman J, Burr NS, Zon LI, Haddad RI. A phase II trial of all-trans retinoic acid (ATRA) in advanced adenoid cystic carcinoma. Oral Oncol. 2021 08; 119:105366. PMID: 34091189.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  3. Fazio M, van Rooijen E, Dang M, van de Hoek G, Ablain J, Mito JK, Yang S, Thomas A, Michael J, Fabo T, Modhurima R, Pessina P, Kaufman CK, Zhou Y, White RM, Zon LI. SATB2 induction of a neural crest mesenchyme-like program drives melanoma invasion and drug resistance. Elife. 2021 02 02; 10. PMID: 33527896.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  4. Fazio M, van Rooijen E, Mito JK, Modhurima R, Weiskopf E, Yang S, Zon LI. Recurrent co-alteration of HDGF and SETDB1 on chromosome 1q drives cutaneous melanoma progression and poor prognosis. Pigment Cell Melanoma Res. 2021 05; 34(3):641-647. PMID: 33064882.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  5. Panse G, Mito JK, Ingram DR, Wani K, Khan S, Lazar AJ, Doyle LA, Wang WL. Radiation-associated sarcomas other than malignant peripheral nerve sheath tumours demonstrate loss of histone H3K27 trimethylation†. Histopathology. 2021 Jan; 78(2):321-326. PMID: 32735735.
    Citations: 4     Fields:    Translation:HumansCells
  6. Mito JK, Qian X, Jo VY, Doyle LA. MYC expression has limited utility in the distinction of undifferentiated radiation-associated sarcomas from sporadic sarcomas and sarcomatoid carcinoma. Histopathology. 2020 Oct; 77(4):667-672. PMID: 32506510.
    Citations: 3     Fields:    Translation:Humans
  7. Mito JK, Mitra D, Barysauskas CM, Mariño-Enriquez A, Morgan EA, Fletcher CDM, Raut CP, Baldini EH, Doyle LA. A Comparison of Outcomes and Prognostic Features for Radiation-Associated Angiosarcoma of the Breast and Other Radiation-Associated Sarcomas. Int J Radiat Oncol Biol Phys. 2019 06 01; 104(2):425-435. PMID: 30703514.
    Citations: 6     Fields:    Translation:Humans
  8. Mito JK, Mitra D, Doyle LA. Radiation-Associated Sarcomas: An Update on Clinical, Histologic, and Molecular Features. Surg Pathol Clin. 2019 Mar; 12(1):139-148. PMID: 30709440.
    Citations: 2     Fields:    Translation:Humans
  9. Ablain J, Xu M, Rothschild H, Jordan RC, Mito JK, Daniels BH, Bell CF, Joseph NM, Wu H, Bastian BC, Zon LI, Yeh I. Human tumor genomics and zebrafish modeling identify SPRED1 loss as a driver of mucosal melanoma. Science. 2018 11 30; 362(6418):1055-1060. PMID: 30385465.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  10. Mito JK, Bishop JA, Sadow PM, Stelow EB, Faquin WC, Mills SE, Krane JF, French CA, Fletcher CDM, Hornick JL, Sholl LM, Jo VY. Immunohistochemical Detection and Molecular Characterization of IDH-mutant Sinonasal Undifferentiated Carcinomas. Am J Surg Pathol. 2018 08; 42(8):1067-1075. PMID: 29683816.
    Citations: 9     Fields:    Translation:Humans
  11. McConnell AM, Mito JK, Ablain J, Dang M, Formichella L, Fisher DE, Zon LI. Neural crest state activation in NRAS driven melanoma, but not in NRAS-driven melanocyte expansion. Dev Biol. 2019 05 15; 449(2):107-114. PMID: 29883661.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  12. Mito JK, Conner JR, Hornick JL, Cibas ES, Qian X. SOX10/keratin dual-color immunohistochemistry: An effective first-line test for the workup of epithelioid malignant neoplasms in FNA and small biopsy specimens. Cancer Cytopathol. 2018 03; 126(3):179-189. PMID: 29385322.
    Citations: 1     Fields:    Translation:Humans
  13. Mito JK, Agoston AT, Dal Cin P, Srivastava A. Prevalence and significance of HMGA2 expression in oesophageal adenocarcinoma. Histopathology. 2017 Dec; 71(6):909-917. PMID: 28710822.
    Citations: 5     Fields:    Translation:Humans
  14. Mito JK, Alexander EK, Angell TE, Barletta JA, Nehs MA, Cibas ES, Krane JF. A modified reporting approach for thyroid FNA in the NIFTP era: A 1-year institutional experience. Cancer Cytopathol. 2017 Nov; 125(11):854-864. PMID: 28902465.
    Citations: 4     Fields:    Translation:Humans
  15. Mito JK, Qian X, Doyle LA, Hornick JL, Jo VY. Role of Histone H3K27 Trimethylation Loss as a Marker for Malignant Peripheral Nerve Sheath Tumor in Fine-Needle Aspiration and Small Biopsy Specimens. Am J Clin Pathol. 2017 Aug 01; 148(2):179-189. PMID: 28898989.
    Citations: 7     Fields:    Translation:HumansCells
  16. Mito JK, Jo VY, Chiosea SI, Dal Cin P, Krane JF. HMGA2 is a specific immunohistochemical marker for pleomorphic adenoma and carcinoma ex-pleomorphic adenoma. Histopathology. 2017 Oct; 71(4):511-521. PMID: 28463429.
    Citations: 10     Fields:    Translation:Humans
  17. Mito JK, Jo VY. BRAF V600E is not a consistent feature of myopericytoma. J Cutan Pathol. 2016 Dec; 43(12):1248-1249. PMID: 27870159.
    Citations:    Fields:    Translation:HumansCells
  18. Sachdeva M, Mito JK, Lee CL, Zhang M, Li Z, Dodd RD, Cason D, Luo L, Ma Y, Van Mater D, Gladdy R, Lev DC, Cardona DM, Kirsch DG. MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. J Clin Invest. 2016 Apr 01; 126(4):1606. PMID: 27035817.
    Citations: 7     Fields:    
  19. Whitley MJ, Cardona DM, Lazarides AL, Spasojevic I, Ferrer JM, Cahill J, Lee CL, Snuderl M, Blazer DG, Hwang ES, Greenup RA, Mosca PJ, Mito JK, Cuneo KC, Larrier NA, O'Reilly EK, Riedel RF, Eward WC, Strasfeld DB, Fukumura D, Jain RK, Lee WD, Griffith LG, Bawendi MG, Kirsch DG, Brigman BE. A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer. Sci Transl Med. 2016 Jan 06; 8(320):320ra4. PMID: 26738797.
    Citations: 83     Fields:    Translation:HumansAnimalsCTClinical Trials
  20. Dodd RD, Sachdeva M, Mito JK, Eward WC, Brigman BE, Ma Y, Dodd L, Kim Y, Lev D, Kirsch DG. Myogenic transcription factors regulate pro-metastatic miR-182. Oncogene. 2016 Apr 07; 35(14):1868-75. PMID: 26234681.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  21. Sachdeva M, Whitley MJ, Mito JK, Ma Y, Lev DC, Cardona DM, Kirsch DG. MicroRNA-16 suppresses metastasis in an orthotopic, but not autochthonous, mouse model of soft tissue sarcoma. Dis Model Mech. 2015 Aug 01; 8(8):867-75. PMID: 26044957.
    Citations:    Fields:    Translation:HumansAnimalsCells
  22. Mueller JL, Fu HL, Mito JK, Whitley MJ, Chitalia R, Erkanli A, Dodd L, Cardona DM, Geradts J, Willett RM, Kirsch DG, Ramanujam N. A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins. Int J Cancer. 2015 Nov 15; 137(10):2403-12. PMID: 25994353.
    Citations: 2     Fields:    Translation:HumansAnimals
  23. Asada K, Canestrari E, Fu X, Li Z, Makowski E, Wu YC, Mito JK, Kirsch DG, Baraban J, Paroo Z. Rescuing dicer defects via inhibition of an anti-dicing nuclease. Cell Rep. 2014 Nov 20; 9(4):1471-81. PMID: 25457613.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  24. Sachdeva M, Mito JK, Lee CL, Zhang M, Li Z, Dodd RD, Cason D, Luo L, Ma Y, Van Mater D, Gladdy R, Lev DC, Cardona DM, Kirsch DG. MicroRNA-182 drives metastasis of primary sarcomas by targeting multiple genes. J Clin Invest. 2014 Oct; 124(10):4305-19. PMID: 25180607.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  25. Blum JM, Añó L, Li Z, Van Mater D, Bennett BD, Sachdeva M, Lagutina I, Zhang M, Mito JK, Dodd LG, Cardona DM, Dodd RD, Williams N, Ma Y, Lepper C, Linardic CM, Mukherjee S, Grosveld GC, Fan CM, Kirsch DG. Distinct and overlapping sarcoma subtypes initiated from muscle stem and progenitor cells. Cell Rep. 2013 Nov 27; 5(4):933-40. PMID: 24239359.
    Citations: 39     Fields:    Translation:AnimalsCells
  26. Fu HL, Mueller JL, Javid MP, Mito JK, Kirsch DG, Ramanujam N, Brown JQ. Optimization of a widefield structured illumination microscope for non-destructive assessment and quantification of nuclear features in tumor margins of a primary mouse model of sarcoma. PLoS One. 2013; 8(7):e68868. PMID: 23894357.
    Citations: 23     Fields:    Translation:AnimalsCells
  27. Dodd RD, Mito JK, Eward WC, Chitalia R, Sachdeva M, Ma Y, Barretina J, Dodd L, Kirsch DG. NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition. Mol Cancer Ther. 2013 Sep; 12(9):1906-17. PMID: 23858101.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  28. Mueller JL, Harmany ZT, Mito JK, Kennedy SA, Kim Y, Dodd L, Geradts J, Kirsch DG, Willett RM, Brown JQ, Ramanujam N. Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins. PLoS One. 2013; 8(6):e66198. PMID: 23824589.
    Citations: 7     Fields:    Translation:Humans
  29. Eward WC, Mito JK, Eward CA, Carter JE, Ferrer JM, Kirsch DG, Brigman BE. A novel imaging system permits real-time in vivo tumor bed assessment after resection of naturally occurring sarcomas in dogs. Clin Orthop Relat Res. 2013 Mar; 471(3):834-42. PMID: 22972654.
    Citations: 8     Fields:    Translation:Animals
  30. Cuneo KC, Mito JK, Javid MP, Ferrer JM, Kim Y, Lee WD, Bawendi MG, Brigman BE, Kirsch DG. Imaging primary mouse sarcomas after radiation therapy using cathepsin-activatable fluorescent imaging agents. Int J Radiat Oncol Biol Phys. 2013 May 01; 86(1):136-42. PMID: 23391816.
    Citations: 11     Fields:    Translation:Animals
  31. Mito JK, Min HD, Ma Y, Carter JE, Brigman BE, Dodd L, Dankort D, McMahon M, Kirsch DG. Oncogene-dependent control of miRNA biogenesis and metastatic progression in a model of undifferentiated pleomorphic sarcoma. J Pathol. 2013 Jan; 229(1):132-40. PMID: 22951975.
    Citations: 23     Fields:    Translation:AnimalsCells
  32. Kim S, Dodd RD, Mito JK, Ma Y, Kim Y, Riedel RF, Kirsch DG. Efficacy of phosphatidylinositol-3 kinase inhibitors in a primary mouse model of undifferentiated pleomorphic sarcoma. Sarcoma. 2012; 2012:680708. PMID: 22619567.
    Citations: 12     
  33. Mito JK, Ferrer JM, Brigman BE, Lee CL, Dodd RD, Eward WC, Marshall LF, Cuneo KC, Carter JE, Ramasunder S, Kim Y, Lee WD, Griffith LG, Bawendi MG, Kirsch DG. Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging. Cancer. 2012 Nov 01; 118(21):5320-30. PMID: 22437667.
    Citations: 28     Fields:    Translation:Animals
  34. Dodd RD, Mito JK, Kirsch DG. Animal models of soft-tissue sarcoma. Dis Model Mech. 2010 Sep-Oct; 3(9-10):557-66. PMID: 20713645.
    Citations: 23     Fields:    Translation:HumansAnimals
  35. Kang Y, Chen BJ, Deoliveira D, Mito J, Chao NJ. Selective enhancement of donor hematopoietic cell engraftment by the CXCR4 antagonist AMD3100 in a mouse transplantation model. PLoS One. 2010 Jun 28; 5(6):e11316. PMID: 20596257.
    Citations: 22     Fields:    Translation:AnimalsCells
  36. Warren EH, Fujii N, Akatsuka Y, Chaney CN, Mito JK, Loeb KR, Gooley TA, Brown ML, Koo KK, Rosinski KV, Ogawa S, Matsubara A, Appelbaum FR, Riddell SR. Therapy of relapsed leukemia after allogeneic hematopoietic cell transplantation with T cells specific for minor histocompatibility antigens. Blood. 2010 May 13; 115(19):3869-78. PMID: 20071660.
    Citations: 86     Fields:    Translation:HumansCellsCTClinical Trials
  37. Mito JK, Riedel RF, Dodd L, Lahat G, Lazar AJ, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG. Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma. PLoS One. 2009 Nov 30; 4(11):e8075. PMID: 19956606.
    Citations: 47     Fields:    Translation:HumansAnimals
  38. Tykodi SS, Fujii N, Vigneron N, Lu SM, Mito JK, Miranda MX, Chou J, Voong LN, Thompson JA, Sandmaier BM, Cresswell P, Van den Eynde B, Riddell SR, Warren EH. C19orf48 encodes a minor histocompatibility antigen recognized by CD8+ cytotoxic T cells from renal cell carcinoma patients. Clin Cancer Res. 2008 Aug 15; 14(16):5260-9. PMID: 18698046.
    Citations: 24     Fields:    Translation:HumansCells
  39. Rosinski KV, Fujii N, Mito JK, Koo KK, Xuereb SM, Sala-Torra O, Gibbs JS, Radich JP, Akatsuka Y, Van den Eynde BJ, Riddell SR, Warren EH. DDX3Y encodes a class I MHC-restricted H-Y antigen that is expressed in leukemic stem cells. Blood. 2008 May 01; 111(9):4817-26. PMID: 18299450.
    Citations: 28     Fields:    Translation:HumansAnimalsCells
  40. Warren EH, Vigneron NJ, Gavin MA, Coulie PG, Stroobant V, Dalet A, Tykodi SS, Xuereb SM, Mito JK, Riddell SR, Van den Eynde BJ. An antigen produced by splicing of noncontiguous peptides in the reverse order. Science. 2006 Sep 08; 313(5792):1444-7. PMID: 16960008.
    Citations: 82     Fields:    Translation:HumansCells
  41. Brickner AG, Evans AM, Mito JK, Xuereb SM, Feng X, Nishida T, Fairfull L, Ferrell RE, Foon KA, Hunt DF, Shabanowitz J, Engelhard VH, Riddell SR, Warren EH. The PANE1 gene encodes a novel human minor histocompatibility antigen that is selectively expressed in B-lymphoid cells and B-CLL. Blood. 2006 May 01; 107(9):3779-86. PMID: 16391015.
    Citations: 43     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.