Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

David H. Sachs, M.D.

Co-Author

This page shows the publications co-authored by David Sachs and Robert Colvin.
Connection Strength

3.687
  1. Immunomodulatory Strategies Directed Toward Tolerance of Vascularized Composite Allografts. Transplantation. 2015 Aug; 99(8):1590-1597.
    View in: PubMed
    Score: 0.163
  2. Pathologic characteristics of transplanted kidney xenografts. J Am Soc Nephrol. 2012 Feb; 23(2):225-35.
    View in: PubMed
    Score: 0.126
  3. Acute renal endothelial injury during marrow recovery in a cohort of combined kidney and bone marrow allografts. Am J Transplant. 2011 Jul; 11(7):1464-77.
    View in: PubMed
    Score: 0.122
  4. Response to 'Tolerance versus immunosuppression: a perspective'. Am J Transplant. 2008 Aug; 8(8):1573-4.
    View in: PubMed
    Score: 0.100
  5. Four stages and lack of stable accommodation in chronic alloantibody-mediated renal allograft rejection in Cynomolgus monkeys. Am J Transplant. 2008 Aug; 8(8):1662-72.
    View in: PubMed
    Score: 0.100
  6. Thrombotic microangiopathy associated with humoral rejection of cardiac xenografts from alpha1,3-galactosyltransferase gene-knockout pigs in baboons. Am J Pathol. 2008 Jun; 172(6):1471-81.
    View in: PubMed
    Score: 0.099
  7. HLA-mismatched renal transplantation without maintenance immunosuppression. N Engl J Med. 2008 Jan 24; 358(4):353-61.
    View in: PubMed
    Score: 0.097
  8. GalT-KO pigs: is the cup half empty or half full? Transplantation. 2007 Jul 15; 84(1):12-4.
    View in: PubMed
    Score: 0.093
  9. Chronic antibody mediated rejection of renal allografts: pathological, serological and immunologic features in nonhuman primates. Am J Transplant. 2006 Aug; 6(8):1790-8.
    View in: PubMed
    Score: 0.086
  10. Thrombotic microangiopathic glomerulopathy in human decay accelerating factor-transgenic swine-to-baboon kidney xenografts. J Am Soc Nephrol. 2005 Sep; 16(9):2732-45.
    View in: PubMed
    Score: 0.081
  11. Xenogeneic thymus transplantation in a pig-to-baboon model. Transplantation. 2003 Feb 15; 75(3):282-91.
    View in: PubMed
    Score: 0.069
  12. Autologous graft-versus-host disease in a porcine bone marrow transplant model. Transplantation. 2002 Aug 27; 74(4):465-71.
    View in: PubMed
    Score: 0.066
  13. Mechanisms of chronic renal allograft rejection. II. Progressive allograft glomerulopathy in miniature swine. Lab Invest. 2002 Jun; 82(6):673-86.
    View in: PubMed
    Score: 0.065
  14. Posttransplant lymphoproliferative disorder associated with an Epstein-Barr-related virus in cynomolgus monkeys. Transplantation. 2002 May 15; 73(9):1431-9.
    View in: PubMed
    Score: 0.065
  15. Persistent rejection of peritubular capillaries and tubules is associated with progressive interstitial fibrosis. Kidney Int. 2002 May; 61(5):1867-79.
    View in: PubMed
    Score: 0.065
  16. Acceptance reaction: intragraft events associated with tolerance to renal allografts in miniature swine. J Am Soc Nephrol. 2000 Dec; 11(12):2371-2380.
    View in: PubMed
    Score: 0.059
  17. Intragraft events preceding chronic renal allograft rejection in a modified tolerance protocol. Kidney Int. 2000 Dec; 58(6):2546-58.
    View in: PubMed
    Score: 0.059
  18. Cutaneous leukocyte lineages in tolerant large animal and immunosuppressed clinical vascularized composite allograft recipients. Am J Transplant. 2021 02; 21(2):582-592.
    View in: PubMed
    Score: 0.058
  19. Mixed chimerism and tolerance without whole body irradiation in a large animal model. J Clin Invest. 2000 Jun; 105(12):1779-89.
    View in: PubMed
    Score: 0.057
  20. Acute humoral xenograft rejection: destruction of the microvascular capillary endothelium in pig-to-nonhuman primate renal grafts. Lab Invest. 2000 Jun; 80(6):815-30.
    View in: PubMed
    Score: 0.057
  21. Thymic transplantation in miniature swine. II. Induction of tolerance by transplantation of composite thymokidneys to thymectomized recipients. J Immunol. 2000 Mar 15; 164(6):3079-86.
    View in: PubMed
    Score: 0.056
  22. Thymic transplantation in miniature swine. I. Development and function of the "thymokidney". Transplantation. 1999 Dec 15; 68(11):1684-92.
    View in: PubMed
    Score: 0.055
  23. Thymic transplantation across an MHC class I barrier in swine. J Immunol. 1999 Oct 01; 163(7):3785-92.
    View in: PubMed
    Score: 0.054
  24. In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9. Transplantation. 1999 Sep 27; 68(6):855-60.
    View in: PubMed
    Score: 0.054
  25. Role of the thymus in transplantation tolerance in miniature swine. III. Surgical manipulation of the thymus interferes with stable induction of tolerance to class I-mismatched renal allografts. Transplantation. 1999 Apr 27; 67(8):1112-9.
    View in: PubMed
    Score: 0.053
  26. Cynomolgus polyoma virus infection: a new member of the polyoma virus family causes interstitial nephritis, ureteritis, and enteritis in immunosuppressed cynomolgus monkeys. Am J Pathol. 1999 Apr; 154(4):1273-84.
    View in: PubMed
    Score: 0.052
  27. Role of the thymus in transplantation tolerance in miniature swine: II. Effect of steroids and age on the induction of tolerance to class I mismatched renal allografts. Transplantation. 1999 Feb 15; 67(3):458-67.
    View in: PubMed
    Score: 0.052
  28. Allogeneic thymo-kidney transplants induce stable tolerance in miniature swine. Transplant Proc. 1999 Feb-Mar; 31(1-2):1199-200.
    View in: PubMed
    Score: 0.052
  29. Porcine kidney and heart transplantation in baboons undergoing a tolerance induction regimen and antibody adsorption. Transplantation. 1999 Jan 15; 67(1):18-30.
    View in: PubMed
    Score: 0.052
  30. Xenotransplantation--caution, but no moratorium. Nat Med. 1998 Apr; 4(4):372-3.
    View in: PubMed
    Score: 0.049
  31. The effects of brain death and ischemia on tolerance induction are organ-specific. Am J Transplant. 2018 05; 18(5):1262-1269.
    View in: PubMed
    Score: 0.049
  32. Role of the thymus in transplantation tolerance in miniature swine. I. Requirement of the thymus for rapid and stable induction of tolerance to class I-mismatched renal allografts. J Exp Med. 1997 Aug 18; 186(4):497-506.
    View in: PubMed
    Score: 0.047
  33. Prolonged Survival Following Pig-to-Primate Liver Xenotransplantation Utilizing Exogenous Coagulation Factors and Costimulation Blockade. Am J Transplant. 2017 Aug; 17(8):2178-2185.
    View in: PubMed
    Score: 0.046
  34. Pig to monkey bone marrow and kidney xenotransplantation. Surgery. 1997 Apr; 121(4):381-91.
    View in: PubMed
    Score: 0.046
  35. Influence of the thymus on transplantation tolerance in miniature swine. Transplant Proc. 1997 Feb-Mar; 29(1-2):1076.
    View in: PubMed
    Score: 0.045
  36. Intragraft cellular events associated with tolerance in pig allografts: the "acceptance reaction". Transplant Proc. 1997 Feb-Mar; 29(1-2):1155.
    View in: PubMed
    Score: 0.045
  37. Prolonged Survival of Pig Skin on Baboons After Administration of Pig Cells Expressing Human CD47. Transplantation. 2017 02; 101(2):316-321.
    View in: PubMed
    Score: 0.045
  38. Induced regulatory T cells in allograft tolerance via transient mixed chimerism. JCI Insight. 2016 Jul 07; 1(10).
    View in: PubMed
    Score: 0.043
  39. A Bridge to Somewhere: 25-day Survival After Pig-to-Baboon Liver Xenotransplantation. Ann Surg. 2016 06; 263(6):1069-71.
    View in: PubMed
    Score: 0.043
  40. Long-term acceptance of primarily vascularized renal allografts in miniature swine. Systemic tolerance versus graft adaptation. Transplantation. 1996 Feb 15; 61(3):503-6.
    View in: PubMed
    Score: 0.042
  41. The Effects of Exogenous Administration of Human Coagulation Factors Following Pig-to-Baboon Liver Xenotransplantation. Am J Transplant. 2016 06; 16(6):1715-1725.
    View in: PubMed
    Score: 0.042
  42. Effects of Lung Cotransplantation on Cardiac Allograft Tolerance Across a Full Major Histocompatibility Complex Barrier in Miniature Swine. Am J Transplant. 2016 Mar; 16(3):979-86.
    View in: PubMed
    Score: 0.041
  43. Recipient-matching of Passenger Leukocytes Prolongs Survival of Donor Lung Allografts in Miniature Swine. Transplantation. 2015 Jul; 99(7):1372-8.
    View in: PubMed
    Score: 0.040
  44. Tolerance of Lung Allografts Achieved in Nonhuman Primates via Mixed Hematopoietic Chimerism. Am J Transplant. 2015 Aug; 15(8):2231-9.
    View in: PubMed
    Score: 0.040
  45. Kidney-induced cardiac allograft tolerance in miniature swine is dependent on MHC-matching of donor cardiac and renal parenchyma. Am J Transplant. 2015 Jun; 15(6):1580-90.
    View in: PubMed
    Score: 0.040
  46. Long-term lung transplantation in nonhuman primates. Am J Transplant. 2015 May; 15(5):1415-20.
    View in: PubMed
    Score: 0.040
  47. Mixed allogeneic chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 1995 Jan 27; 59(2):256-62.
    View in: PubMed
    Score: 0.039
  48. Use of CTLA4Ig for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Am J Transplant. 2014 Dec; 14(12):2704-12.
    View in: PubMed
    Score: 0.039
  49. Long-term results in recipients of combined HLA-mismatched kidney and bone marrow transplantation without maintenance immunosuppression. Am J Transplant. 2014 Jul; 14(7):1599-611.
    View in: PubMed
    Score: 0.038
  50. Interleukin-2 reverses the ability of cyclosporine to induce tolerance to class I disparate kidney allografts in miniature swine. Transplant Proc. 1993 Feb; 25(1 Pt 1):322-3.
    View in: PubMed
    Score: 0.034
  51. Overcoming memory T-cell responses for induction of delayed tolerance in nonhuman primates. Am J Transplant. 2012 Feb; 12(2):330-40.
    View in: PubMed
    Score: 0.031
  52. Contributions of direct and indirect alloresponses to chronic rejection of kidney allografts in nonhuman primates. J Immunol. 2011 Nov 01; 187(9):4589-97.
    View in: PubMed
    Score: 0.031
  53. Host alloreactive memory T cells influence tolerance to kidney allografts in nonhuman primates. Sci Transl Med. 2011 Jun 08; 3(86):86ra51.
    View in: PubMed
    Score: 0.031
  54. Stem cell mobilization and collection for induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. J Surg Res. 2011 Jun 15; 168(2):294-300.
    View in: PubMed
    Score: 0.028
  55. B-cell immunity in the context of T-cell tolerance after combined kidney and bone marrow transplantation in humans. Am J Transplant. 2009 Sep; 9(9):2126-35.
    View in: PubMed
    Score: 0.027
  56. Rejection of cardiac xenografts transplanted from alpha1,3-galactosyltransferase gene-knockout (GalT-KO) pigs to baboons. Am J Transplant. 2008 Dec; 8(12):2516-26.
    View in: PubMed
    Score: 0.026
  57. Limited efficacy and unacceptable toxicity of cyclophosphamide for the induction of mixed chimerism and renal allograft tolerance in cynomolgus monkeys. Transplantation. 2008 Aug 27; 86(4):615-9.
    View in: PubMed
    Score: 0.025
  58. Depletion of CD8 memory T cells for induction of tolerance of a previously transplanted kidney allograft. Am J Transplant. 2007 May; 7(5):1055-61.
    View in: PubMed
    Score: 0.023
  59. Monitoring antidonor alloantibodies as a predictive assay for renal allograft tolerance/long-term observations in nonhuman primates. Transplantation. 2006 Sep 27; 82(6):819-25.
    View in: PubMed
    Score: 0.022
  60. Myeloma responses and tolerance following combined kidney and nonmyeloablative marrow transplantation: in vivo and in vitro analyses. Am J Transplant. 2006 Sep; 6(9):2121-33.
    View in: PubMed
    Score: 0.022
  61. My most interesting cases. Clin Transpl. 2006; 580-2.
    View in: PubMed
    Score: 0.021
  62. CD154 blockade for induction of mixed chimerism and prolonged renal allograft survival in nonhuman primates. Am J Transplant. 2004 Sep; 4(9):1391-8.
    View in: PubMed
    Score: 0.019
  63. Thrombophilia associated with anti-CD154 monoclonal antibody treatment and its prophylaxis in nonhuman primates. Transplantation. 2004 Feb 15; 77(3):460-2.
    View in: PubMed
    Score: 0.018
  64. Xenogeneic thymokidney and thymic tissue transplantation in a pig-to-baboon model: I. Evidence for pig-specific T-cell unresponsiveness. Transplantation. 2003 May 27; 75(10):1615-24.
    View in: PubMed
    Score: 0.017
  65. Pig kidney transplantation in baboons: anti-Gal(alpha)1-3Gal IgM alone is associated with acute humoral xenograft rejection and disseminated intravascular coagulation. Transplantation. 2001 Dec 15; 72(11):1743-52.
    View in: PubMed
    Score: 0.016
  66. Long-term islet allograft function in the absence of chronic immunosuppression: a case report of a nonhuman primate previously made tolerant to a renal allograft from the same donor. Transplantation. 2001 Jul 27; 72(2):351-4.
    View in: PubMed
    Score: 0.015
  67. Comparison of horse antithymocyte globulin with other T cell-depleting antibodies for induction of chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):116-7.
    View in: PubMed
    Score: 0.015
  68. Costimulatory blockade for induction of mixed chimerism and renal allograft tolerance in nonhuman primates. Transplant Proc. 2001 Feb-Mar; 33(1-2):221-2.
    View in: PubMed
    Score: 0.015
  69. Association of natural killer cell depletion with induction of mixed chimerism and allograft tolerance in non-human primates. Transplantation. 2000 Jul 27; 70(2):368-74.
    View in: PubMed
    Score: 0.014
  70. Thromboembolic complications after treatment with monoclonal antibody against CD40 ligand. Nat Med. 2000 Feb; 6(2):114.
    View in: PubMed
    Score: 0.014
  71. Tolerance in a concordant nonhuman primate model. Transplantation. 1999 Dec 15; 68(11):1708-16.
    View in: PubMed
    Score: 0.014
  72. Long-term outcome and alloantibody production in a non-myeloablative regimen for induction of renal allograft tolerance. Transplantation. 1999 Dec 15; 68(11):1767-75.
    View in: PubMed
    Score: 0.014
  73. Transplantation in miniature swine. VI. Factors influencing survival of renal allografts. Transplantation. 1979 Jul; 28(1):18-23.
    View in: PubMed
    Score: 0.013
  74. Transplantation in miniature swine. VII. Evidence for cellular immune mechanisms in hyperacute rejection of renal alografts. Transplantation. 1979 Jul; 28(1):24-30.
    View in: PubMed
    Score: 0.013
  75. Human CD4+ T cells mediate rejection of porcine xenografts. J Immunol. 1999 May 01; 162(9):5256-62.
    View in: PubMed
    Score: 0.013
  76. Evidence for cellular immune mechanisms in hyperacute rejection of renal allografts in miniature swine. Transplant Proc. 1979 Mar; 11(1):790-2.
    View in: PubMed
    Score: 0.013
  77. Disseminated intravascular coagulation in association with the delayed rejection of pig-to-baboon renal xenografts. Transplantation. 1998 Dec 15; 66(11):1439-50.
    View in: PubMed
    Score: 0.013
  78. Demonstration of multilineage chimerism in a nonhuman primate concordant xenograft model. Xenotransplantation. 1998 Nov; 5(4):298-304.
    View in: PubMed
    Score: 0.013
  79. Expression of an allogeneic MHC DRB transgene, through retroviral transduction of bone marrow, induces specific reduction of alloreactivity. Transplantation. 1997 Nov 27; 64(10):1414-23.
    View in: PubMed
    Score: 0.012
  80. Modifications of the conditioning regimen for achieving mixed chimerism and donor-specific tolerance in cynomolgus monkeys. Transplantation. 1997 Sep 15; 64(5):709-16.
    View in: PubMed
    Score: 0.012
  81. Human cell-mediated rejection of porcine xenografts in an immunodeficient mouse model. Transplantation. 1997 May 15; 63(9):1331-8.
    View in: PubMed
    Score: 0.012
  82. Mixed chimerism and transplantation tolerance induced by a nonlethal preparative regimen in cynomolgus monkeys. Transplant Proc. 1997 Feb-Mar; 29(1-2):1218.
    View in: PubMed
    Score: 0.011
  83. Graft-vs-host tolerance in mixed allogeneic chimerism. Transplant Proc. 1997 Feb-Mar; 29(1-2):1222-3.
    View in: PubMed
    Score: 0.011
  84. A study of tolerance in a concordant xenograft model. Transplant Proc. 1997 Feb-Mar; 29(1-2):923-4.
    View in: PubMed
    Score: 0.011
  85. Molecular and cellular events implicated in local tolerance to kidney allografts in miniature swine. Transplantation. 1997 Jan 15; 63(1):26-33.
    View in: PubMed
    Score: 0.011
  86. A mixed chimerism approach to renal transplantation between concordant nonhuman primate species. Transplant Proc. 1996 Apr; 28(2):761.
    View in: PubMed
    Score: 0.011
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.