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profileAlexander Bartelt

TitleVisiting Scientist
InstitutionHarvard T.H. Chan School of Public Health
DepartmentGenetics and Complex Diseases
AddressHarvard School of Public Health
Bldg 1 Room 605
665 Huntington Ave
Boston MA 02115
Phone6174321951
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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Bartelt A, Widenmaier SB, Schlein C, Johann K, Goncalves RLS, Eguchi K, Fischer AW, Parlakgül G, Snyder NA, Nguyen TB, Bruns OT, Franke D, Bawendi MG, Lynes MD, Leiria LO, Tseng YH, Inouye KE, Arruda AP, Hotamisligil GS. Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity. Nat Med. 2018 Feb 05. PMID: 29400713.
    View in: PubMed
  2. Widenmaier SB, Snyder NA, Nguyen TB, Arduini A, Lee GY, Arruda AP, Saksi J, Bartelt A, Hotamisligil GS. NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis. Cell. 2017 Nov 16; 171(5):1094-1109.e15. PMID: 29149604.
    View in: PubMed
  3. Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. Corrigendum: The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nat Med. 2017 Nov 07; 23(11):1384. PMID: 29117173.
    View in: PubMed
  4. Bartelt A, Jeschke A, Müller B, Gaziano I, Morales M, Yorgan T, Heckt T, Heine M, Gagel RF, Emeson RB, Amling M, Niemeier A, Heeren J, Schinke T, Keller J. Differential effects of Calca-derived peptides in male mice with diet-induced obesity. PLoS One. 2017; 12(6):e0180547. PMID: 28666011.
    View in: PubMed
  5. Bartelt A, Koehne T, Tödter K, Reimer R, Müller B, Behler-Janbeck F, Heeren J, Scheja L, Niemeier A. Quantification of Bone Fatty Acid Metabolism and Its Regulation by Adipocyte Lipoprotein Lipase. Int J Mol Sci. 2017 Jun 13; 18(6). PMID: 28608812.
    View in: PubMed
  6. Bartelt A, John C, Schaltenberg N, Berbée JFP, Worthmann A, Cherradi ML, Schlein C, Piepenburg J, Boon MR, Rinninger F, Heine M, Toedter K, Niemeier A, Nilsson SK, Fischer M, Wijers SL, van Marken Lichtenbelt W, Scheja L, Rensen PCN, Heeren J. Thermogenic adipocytes promote HDL turnover and reverse cholesterol transport. Nat Commun. 2017 Apr 19; 8:15010. PMID: 28422089.
    View in: PubMed
  7. Bruns OT, Bischof TS, Harris DK, Franke D, Shi Y, Riedemann L, Bartelt A, Jaworski FB, Carr JA, Rowlands CJ, Wilson MWB, Chen O, Wei H, Hwang GW, Montana DM, Coropceanu I, Achorn OB, Kloepper J, Heeren J, So PTC, Fukumura D, Jensen KF, Jain RK, Bawendi MG. Next-generation in vivo optical imaging with short-wave infrared quantum dots. Nat Biomed Eng. 2017; 1. PMID: 29119058.
    View in: PubMed
  8. Lynes MD, Leiria LO, Lundh M, Bartelt A, Shamsi F, Huang TL, Takahashi H, Hirshman MF, Schlein C, Lee A, Baer LA, May FJ, Gao F, Narain NR, Chen EY, Kiebish MA, Cypess AM, Blüher M, Goodyear LJ, Hotamisligil GS, Stanford KI, Tseng YH. The cold-induced lipokine 12,13-diHOME promotes fatty acid transport into brown adipose tissue. Nat Med. 2017 May; 23(5):631-637. PMID: 28346411.
    View in: PubMed
  9. Wagner T, Bartelt A, Schlein C, Heeren J. Genetic Dissection of Tissue-Specific Apolipoprotein E Function for Hypercholesterolemia and Diet-Induced Obesity. PLoS One. 2015; 10(12):e0145102. PMID: 26695075; PMCID: PMC4687855.
  10. Longchamp A, Tao M, Bartelt A, Ding K, Lynch L, Hine C, Corpataux JM, Kristal BS, Mitchell JR, Ozaki CK. Surgical injury induces local and distant adipose tissue browning. Adipocyte. 2016 Apr-Jun; 5(2):163-74. PMID: 27386152; PMCID: PMC4916868 [Available on 11/20/16].
  11. Lasrich D, Bartelt A, Grewal T, Heeren J. Apolipoprotein E promotes lipid accumulation and differentiation in human adipocytes. Exp Cell Res. 2015 Sep 10; 337(1):94-102. PMID: 26201081.
    View in: PubMed
  12. Berbée JF, Boon MR, Khedoe PP, Bartelt A, Schlein C, Worthmann A, Kooijman S, Hoeke G, Mol IM, John C, Jung C, Vazirpanah N, Brouwers LP, Gordts PL, Esko JD, Hiemstra PS, Havekes LM, Scheja L, Heeren J, Rensen PC. Brown fat activation reduces hypercholesterolaemia and protects from atherosclerosis development. Nat Commun. 2015 Mar 10; 6:6356. PMID: 25754609; PMCID: PMC4366535.
  13. Heine M, Bartelt A, Bruns OT, Bargheer D, Giemsa A, Freund B, Scheja L, Waurisch C, Eychmüller A, Reimer R, Weller H, Nielsen P, Heeren J. The cell-type specific uptake of polymer-coated or micelle-embedded QDs and SPIOs does not provoke an acute pro-inflammatory response in the liver. Beilstein J Nanotechnol. 2014; 5:1432-1440. PMID: 25247125; PMCID: PMC4168844.
  14. Bartelt A, Beil FT, Müller B, Koehne T, Yorgan TA, Heine M, Yilmaz T, Rüther W, Heeren J, Schinke T, Niemeier A. Hepatic lipase is expressed by osteoblasts and modulates bone remodeling in obesity. Bone. 2014 May; 62:90-8. PMID: 24440515.
    View in: PubMed
  15. Albers K, Schlein C, Wenner K, Lohse P, Bartelt A, Heeren J, Santer R, Merkel M. Homozygosity for a partial deletion of apoprotein A-V signal peptide results in intracellular missorting of the protein and chylomicronemia in a breast-fed infant. Atherosclerosis. 2014 Mar; 233(1):97-103. PMID: 24529129.
    View in: PubMed
  16. Bartelt A, Heeren J. Adipose tissue browning and metabolic health. Nat Rev Endocrinol. 2014 Jan; 10(1):24-36. PMID: 24146030.
    View in: PubMed
  17. Dieckmann M, Beil FT, Mueller B, Bartelt A, Marshall RP, Koehne T, Amling M, Ruether W, Cooper JA, Humphries SE, Herz J, Niemeier A. Human apolipoprotein E isoforms differentially affect bone mass and turnover in vivo. J Bone Miner Res. 2013 Feb; 28(2):236-45. PMID: 22991192; PMCID: PMC3547162.
  18. Eissing L, Scherer T, Tödter K, Knippschild U, Greve JW, Buurman WA, Pinnschmidt HO, Rensen SS, Wolf AM, Bartelt A, Heeren J, Buettner C, Scheja L. De novo lipogenesis in human fat and liver is linked to ChREBP-ß and metabolic health. Nat Commun. 2013; 4:1528. PMID: 23443556; PMCID: PMC3740744.
  19. Bartelt A, Weigelt C, Cherradi ML, Niemeier A, Tödter K, Heeren J, Scheja L. Effects of adipocyte lipoprotein lipase on de novo lipogenesis and white adipose tissue browning. Biochim Biophys Acta. 2013 May; 1831(5):934-42. PMID: 23228690.
    View in: PubMed
  20. Freund B, Tromsdorf UI, Bruns OT, Heine M, Giemsa A, Bartelt A, Salmen SC, Raabe N, Heeren J, Ittrich H, Reimer R, Hohenberg H, Schumacher U, Weller H, Nielsen P. A simple and widely applicable method to 59Fe-radiolabel monodisperse superparamagnetic iron oxide nanoparticles for in vivo quantification studies. ACS Nano. 2012 Aug 28; 6(8):7318-25. PMID: 22793497.
    View in: PubMed
  21. Gordts PL, Bartelt A, Nilsson SK, Annaert W, Christoffersen C, Nielsen LB, Heeren J, Roebroek AJ. Impaired LDL receptor-related protein 1 translocation correlates with improved dyslipidemia and atherosclerosis in apoE-deficient mice. PLoS One. 2012; 7(6):e38330. PMID: 22701627; PMCID: PMC3368875.
  22. Bartelt A, Heeren J. The holy grail of metabolic disease: brown adipose tissue. Curr Opin Lipidol. 2012 Jun; 23(3):190-5. PMID: 22449813.
    View in: PubMed
  23. Bartelt A, Merkel M, Heeren J. A new, powerful player in lipoprotein metabolism: brown adipose tissue. J Mol Med (Berl). 2012 Aug; 90(8):887-93. PMID: 22231746.
    View in: PubMed
  24. Bartelt A, Bruns OT, Reimer R, Hohenberg H, Ittrich H, Peldschus K, Kaul MG, Tromsdorf UI, Weller H, Waurisch C, Eychmüller A, Gordts PL, Rinninger F, Bruegelmann K, Freund B, Nielsen P, Merkel M, Heeren J. Brown adipose tissue activity controls triglyceride clearance. Nat Med. 2011 Feb; 17(2):200-5. PMID: 21258337.
    View in: PubMed
  25. Cuchet D, Sykes A, Nicolas A, Orr A, Murray J, Sirma H, Heeren J, Bartelt A, Everett RD. PML isoforms I and II participate in PML-dependent restriction of HSV-1 replication. J Cell Sci. 2011 Jan 15; 124(Pt 2):280-91. PMID: 21172801; PMCID: PMC3010193.
  26. Prawitt J, Beil FT, Marshall RP, Bartelt A, Ruether W, Heeren J, Amling M, Staels B, Niemeier A. Short-term activation of liver X receptors inhibits osteoblasts but long-term activation does not have an impact on murine bone in vivo. Bone. 2011 Feb; 48(2):339-46. PMID: 20817130.
    View in: PubMed
  27. Bartelt A, Beil FT, Schinke T, Roeser K, Ruether W, Heeren J, Niemeier A. Apolipoprotein E-dependent inverse regulation of vertebral bone and adipose tissue mass in C57Bl/6 mice: modulation by diet-induced obesity. Bone. 2010 Oct; 47(4):736-45. PMID: 20633710.
    View in: PubMed
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