Harvard Catalyst Profiles

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Gary Ping-Hao Ho, M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 2022 George Cotzias Memorial Fellowship (HO, GARY P. H.) Sep 1, 2022 - Aug 31, 2025
    American Parkinson Disease Association
    Leveraging protein palmitoylation to correct vesicle trafficking defects in Parkinson disease
    Role: Principal Investigator
  2. K08NS110876 (HO, GARY P. H.) Jul 1, 2019 - Jun 30, 2024
    NIH
    Protein palmitoylation in synuclein pathophysiology
    Role: Principal Investigator
  3. R25NS065743 (Cash, Sydney) Jul 1, 2016 - Jun 30, 2019
    NIH/NINDS
    The role of Gaucher Disease glucocerebrosidase in the dynamics of alpha-synuclein multimerization (Neuroscience Resident Research Program)
    Role: Supplement Awardee

Featured Content

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Ndayisaba A, Pitaro AT, Willett AS, Jones KA, de Gusmao CM, Olsen AL, Kim J, Rissanen E, Woods JK, Srinivasan SR, Nagy A, Nagy A, Mesidor M, Cicero S, Patel V, Oakley DH, Tuncali I, Taglieri-Noble K, Clark EC, Paulson J, Krolewski RC, Ho GP, Hung AY, Wills AM, Hayes MT, Macmore JP, Warren L, Bower PG, Langer CB, Kellerman LR, Humphreys CW, Glanz BI, Dielubanza EJ, Frosch MP, Freeman RL, Gibbons CH, Stefanova N, Chitnis T, Weiner HL, Scherzer CR, Scholz SW, Vuzman D, Cox LM, Wenning G, Schmahmann JD, Novak P, Young GS, Feany MB, Singhal T, Khurana V. Clinical Trial-Ready Patient Cohorts for Multiple System Atrophy: Coupling Biospecimen and iPSC Banking to Longitudinal Deep-Phenotyping. Cerebellum. 2022 Oct 03. PMID: 36190676; PMCID: PMC9527378.
    Citations:    Fields:    
  2. Fanning S, Cirka H, Thies JL, Jeong J, Niemi SM, Yoon J, Ho GPH, Pacheco JA, Dettmer U, Liu L, Clish CB, Hodgetts KJ, Hutchinson JN, Muratore CR, Caldwell GA, Caldwell KA, Selkoe D. Lipase regulation of cellular fatty acid homeostasis as a Parkinson's disease therapeutic strategy. NPJ Parkinsons Dis. 2022 Jun 09; 8(1):74. PMID: 35680956; PMCID: PMC9184586.
    Citations:    
  3. Ho GPH, Ramalingam N, Imberdis T, Wilkie EC, Dettmer U, Selkoe DJ. Upregulation of Cellular Palmitoylation Mitigates a-Synuclein Accumulation and Neurotoxicity. Mov Disord. 2021 02; 36(2):348-359. PMID: 33103814; PMCID: PMC8887921.
    Citations: 8     Fields:    Translation:HumansAnimalsCells
  4. Terry-Kantor E, Tripathi A, Imberdis T, LaVoie ZM, Ho GPH, Selkoe D, Fanning S, Ramalingam N, Dettmer U. Rapid Alpha-Synuclein Toxicity in a Neural Cell Model and Its Rescue by a Stearoyl-CoA Desaturase Inhibitor. Int J Mol Sci. 2020 Jul 22; 21(15). PMID: 32707907.
    Citations: 6     Fields:    Translation:HumansCells
  5. Imberdis T, Negri J, Ramalingam N, Terry-Kantor E, Ho GPH, Fanning S, Stirtz G, Kim TE, Levy OA, Young-Pearse TL, Selkoe D, Dettmer U. Cell models of lipid-rich a-synuclein aggregation validate known modifiers of a-synuclein biology and identify stearoyl-CoA desaturase. Proc Natl Acad Sci U S A. 2019 10 08; 116(41):20760-20769. PMID: 31548371.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  6. Fanning S, Haque A, Imberdis T, Baru V, Barrasa MI, Nuber S, Termine D, Ramalingam N, Ho GPH, Noble T, Sandoe J, Lou Y, Landgraf D, Freyzon Y, Newby G, Soldner F, Terry-Kantor E, Kim TE, Hofbauer HF, Becuwe M, Jaenisch R, Pincus D, Clish CB, Walther TC, Farese RV, Srinivasan S, Welte MA, Kohlwein SD, Dettmer U, Lindquist S, Selkoe D. Lipidomic Analysis of a-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment. Mol Cell. 2019 03 07; 73(5):1001-1014.e8. PMID: 30527540; PMCID: PMC6408259.
    Citations: 81     Fields:    Translation:HumansAnimalsCells
  7. Ho GPH, Gamaldo CE, Gulyani S, Salas RE. Restless Legs Syndrome/Willis Ekbom Disease: Long-Term Consequences and Management, Manconi and García-Borreguero, eds . Impulsive Behaviors: Definition, Prevalence, Neurobiology, and Management. 2017; 215-227.
  8. Ho GP, Brizzi KT, Meredith DM, Laws ER, Berkowitz AL. Clinical Reasoning: A 58-year-old woman with loss of vision in her left eye. Neurology. 2016 Mar 08; 86(10):e101-7. PMID: 26952304.
    Citations:    Fields:    Translation:Humans
  9. Cha JY, Kim HJ, Yu JH, Xu J, Kim D, Paul BD, Choi H, Kim S, Lee YJ, Ho GP, Rao F, Snyder SH, Kim JW. Dexras1 mediates glucocorticoid-associated adipogenesis and diet-induced obesity. Proc Natl Acad Sci U S A. 2013 Dec 17; 110(51):20575-80. PMID: 24297897.
    Citations: 15     Fields:    Translation:AnimalsCells
  10. Ho GP, Selvakumar B, Mukai J, Hester LD, Wang Y, Gogos JA, Snyder SH. S-nitrosylation and S-palmitoylation reciprocally regulate synaptic targeting of PSD-95. Neuron. 2011 Jul 14; 71(1):131-41. PMID: 21745643.
    Citations: 85     Fields:    Translation:HumansAnimalsCells
  11. Mustafa AK, Kumar M, Selvakumar B, Ho GP, Ehmsen JT, Barrow RK, Amzel LM, Snyder SH. Nitric oxide S-nitrosylates serine racemase, mediating feedback inhibition of D-serine formation. Proc Natl Acad Sci U S A. 2007 Feb 20; 104(8):2950-5. PMID: 17293453; PMCID: PMC1815287.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  12. Ho GP, Margossian S, Taniguchi T, D'Andrea AD. Phosphorylation of FANCD2 on two novel sites is required for mitomycin C resistance. Mol Cell Biol. 2006 Sep; 26(18):7005-15. PMID: 16943440; PMCID: PMC1592857.
    Citations: 66     Fields:    Translation:HumansCells
  13. Andreassen PR, Ho GP, D'Andrea AD. DNA damage responses and their many interactions with the replication fork. Carcinogenesis. 2006 May; 27(5):883-92. PMID: 16490739.
    Citations: 36     Fields:    Translation:HumansAnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.