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Srigokul Upadhyayula, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Mondal C, Gacha-Garay MJ, Larkin KA, Adikes RC, Di Martino JS, Chien CC, Fraser M, Eni-Aganga I, Agullo-Pascual E, Cialowicz K, Ozbek U, Naba A, Gaitas A, Fu TM, Upadhyayula S, Betzig E, Matus DQ, Martin BL, Bravo-Cordero JJ. A proliferative to invasive switch is mediated by srGAP1 downregulation through the activation of TGF-ß2 signaling. Cell Rep. 2022 09 20; 40(12):111358. PMID: 36130489; PMCID: PMC9596226.
    Citations: 1     Fields:    Translation:AnimalsCells
  2. Sheu SH, Upadhyayula S, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, Banala S, Freeman M, Xu CS, Kirchhausen T, Hess HF, Lavis L, Li Y, Chaumont-Dubel S, Clapham DE. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022 09 01; 185(18):3390-3407.e18. PMID: 36055200; PMCID: PMC9789380.
    Citations: 4     Fields:    Translation:Cells
  3. Jin M, Shirazinejad C, Wang B, Yan A, Schöneberg J, Upadhyayula S, Xu K, Drubin DG. Branched actin networks are organized for asymmetric force production during clathrin-mediated endocytosis in mammalian cells. Nat Commun. 2022 06 22; 13(1):3578. PMID: 35732852; PMCID: PMC9217951.
    Citations: 1     Fields:    Translation:Animals
  4. Chou YY, Upadhyayula S, Houser J, He K, Skillern W, Scanavachi G, Dang S, Sanyal A, Ohashi KG, Di Caprio G, Kreutzberger AJB, Vadakkan TJ, Kirchhausen T. Inherited nuclear pore substructures template post-mitotic pore assembly. Dev Cell. 2021 06 21; 56(12):1786-1803.e9. PMID: 34129835; PMCID: PMC8261643.
    Citations: 3     Fields:    Translation:HumansCells
  5. Gao R, Yu CJ, Gao L, Piatkevich KD, Neve RL, Munro JB, Upadhyayula S, Boyden ES. A highly homogeneous polymer composed of tetrahedron-like monomers for high-isotropy expansion microscopy. Nat Nanotechnol. 2021 06; 16(6):698-707. PMID: 33782587; PMCID: PMC8197733.
    Citations: 9     Fields:    Translation:HumansAnimalsCells
  6. Ozawa M, Hiver S, Yamamoto T, Shibata T, Upadhyayula S, Mimori-Kiyosue Y, Takeichi M. Adherens junction regulates cryptic lamellipodia formation for epithelial cell migration. J Cell Biol. 2020 10 05; 219(10). PMID: 32886101.
    Citations: 10     Fields:    Translation:HumansCells
  7. Salman MM, Marsh G, Kusters I, Delincé M, Di Caprio G, Upadhyayula S, de Nola G, Hunt R, Ohashi KG, Gray T, Shimizu F, Sano Y, Kanda T, Obermeier B, Kirchhausen T. Design and Validation of a Human Brain Endothelial Microvessel-on-a-Chip Open Microfluidic Model Enabling Advanced Optical Imaging. Front Bioeng Biotechnol. 2020; 8:573775. PMID: 33117784.
    Citations: 50     
  8. He K, Song E, Upadhyayula S, Dang S, Gaudin R, Skillern W, Bu K, Capraro BR, Rapoport I, Kusters I, Ma M, Kirchhausen T. Dynamics of Auxilin 1 and GAK in clathrin-mediated traffic. J Cell Biol. 2020 03 02; 219(3). PMID: 31962345; PMCID: PMC7054993.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  9. Pascolutti R, Algisi V, Conte A, Raimondi A, Pasham M, Upadhyayula S, Gaudin R, Maritzen T, Barbieri E, Caldieri G, Tordonato C, Confalonieri S, Freddi S, Malabarba MG, Maspero E, Polo S, Tacchetti C, Haucke V, Kirchhausen T, Di Fiore PP, Sigismund S. Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling. Cell Rep. 2019 06 04; 27(10):3049-3061.e6. PMID: 31167147.
    Citations: 24     Fields:    Translation:HumansAnimalsCells
  10. Gao R, Asano SM, Upadhyayula S, Pisarev I, Milkie DE, Liu TL, Singh V, Graves A, Huynh GH, Zhao Y, Bogovic J, Colonell J, Ott CM, Zugates C, Tappan S, Rodriguez A, Mosaliganti KR, Sheu SH, Pasolli HA, Pang S, Xu CS, Megason SG, Hess H, Lippincott-Schwartz J, Hantman A, Rubin GM, Kirchhausen T, Saalfeld S, Aso Y, Boyden ES, Betzig E. Cortical column and whole-brain imaging with molecular contrast and nanoscale resolution. Science. 2019 01 18; 363(6424). PMID: 30655415; PMCID: PMC6481610.
    Citations: 89     Fields:    Translation:HumansAnimalsCells
  11. Swinburne IA, Mosaliganti KR, Upadhyayula S, Liu TL, Hildebrand DGC, Tsai TY, Chen A, Al-Obeidi E, Fass AK, Malhotra S, Engert F, Lichtman JW, Kirchhausen T, Betzig E, Megason SG. Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure. Elife. 2018 06 19; 7. PMID: 29916365.
    Citations: 7     Fields:    Translation:Animals
  12. Liu TL, Upadhyayula S, Milkie DE, Singh V, Wang K, Swinburne IA, Mosaliganti KR, Collins ZM, Hiscock TW, Shea J, Kohrman AQ, Medwig TN, Dambournet D, Forster R, Cunniff B, Ruan Y, Yashiro H, Scholpp S, Meyerowitz EM, Hockemeyer D, Drubin DG, Martin BL, Matus DQ, Koyama M, Megason SG, Kirchhausen T, Betzig E. Observing the cell in its native state: Imaging subcellular dynamics in multicellular organisms. Science. 2018 04 20; 360(6386). PMID: 29674564.
    Citations: 141     Fields:    Translation:HumansAnimalsCells
  13. Böcking T, Upadhyayula S, Rapoport I, Capraro BR, Kirchhausen T. Reconstitution of Clathrin Coat Disassembly for Fluorescence Microscopy and Single-Molecule Analysis. Methods Mol Biol. 2018; 1847:121-146. PMID: 30129014; PMCID: PMC6669891.
    Citations: 2     Fields:    Translation:Cells
  14. He K, Marsland R, Upadhyayula S, Song E, Dang S, Capraro BR, Wang W, Skillern W, Gaudin R, Ma M, Kirchhausen T. Dynamics of phosphoinositide conversion in clathrin-mediated endocytic traffic. Nature. 2017 12 21; 552(7685):410-414. PMID: 29236694.
    Citations: 59     Fields:    Translation:HumansAnimalsCells
  15. Adell MAY, Migliano SM, Upadhyayula S, Bykov YS, Sprenger S, Pakdel M, Vogel GF, Jih G, Skillern W, Behrouzi R, Babst M, Schmidt O, Hess MW, Briggs JA, Kirchhausen T, Teis D. Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding. Elife. 2017 10 11; 6. PMID: 29019322.
    Citations: 51     Fields:    Translation:AnimalsCells
  16. Paulsen BS, Mandal PK, Frock RL, Boyraz B, Yadav R, Upadhyayula S, Gutierrez-Martinez P, Ebina W, Fasth A, Kirchhausen T, Talkowski ME, Agarwal S, Alt FW, Rossi DJ. Ectopic expression of RAD52 and dn53BP1 improves homology-directed repair during CRISPR-Cas9 genome editing. Nat Biomed Eng. 2017 11; 1(11):878-888. PMID: 31015609; PMCID: PMC6918705.
    Citations: 32     Fields:    Translation:HumansCells
  17. Salgado EN, Upadhyayula S, Harrison SC. Single-Particle Detection of Transcription following Rotavirus Entry. J Virol. 2017 Sep 15; 91(18). PMID: 28701394; PMCID: PMC5571246.
    Citations: 10     Fields:    
  18. Schuler MH, Lewandowska A, Caprio GD, Skillern W, Upadhyayula S, Kirchhausen T, Shaw JM, Cunniff B. Miro1-mediated mitochondrial positioning shapes intracellular energy gradients required for cell migration. Mol Biol Cell. 2017 Aug 01; 28(16):2159-2169. PMID: 28615318; PMCID: PMC5531732.
    Citations: 58     Fields:    Translation:AnimalsCells
  19. Wang H, Becuwe M, Housden BE, Chitraju C, Porras AJ, Graham MM, Liu XN, Thiam AR, Savage DB, Agarwal AK, Garg A, Olarte MJ, Lin Q, Fröhlich F, Hannibal-Bach HK, Upadhyayula S, Perrimon N, Kirchhausen T, Ejsing CS, Walther TC, Farese RV. Seipin is required for converting nascent to mature lipid droplets. Elife. 2016 Aug 26; 5. PMID: 27564575; PMCID: PMC5035145.
    Citations: 132     Fields:    
  20. Aguet F, Upadhyayula S, Gaudin R, Chou YY, Cocucci E, He K, Chen BC, Mosaliganti K, Pasham M, Skillern W, Legant WR, Liu TL, Findlay G, Marino E, Danuser G, Megason S, Betzig E, Kirchhausen T. Membrane dynamics of dividing cells imaged by lattice light-sheet microscopy. Mol Biol Cell. 2016 11 07; 27(22):3418-3435. PMID: 27535432; PMCID: PMC5221578.
    Citations: 40     Fields:    Translation:AnimalsCells
  21. Upadhyayula S, Nuñez V, Espinoza EM, Larsen JM, Bao D, Shi D, Mac JT, Anvari B, Vullev VI. Correction: Photoinduced dynamics of a cyanine dye: parallel pathways of non-radiative deactivation involving multiple excited-state twisted transients. Chem Sci. 2015 05 01; 6(5):3269. PMID: 30123451; PMCID: PMC6063286.
  22. Upadhyayula S, Nuñez V, Espinoza EM, Larsen JM, Bao D, Shi D, Mac JT, Anvari B, Vullev VI. Photoinduced dynamics of a cyanine dye: parallel pathways of non-radiative deactivation involving multiple excited-state twisted transients. Chem Sci. 2015 Apr 01; 6(4):2237-2251. PMID: 29449923; PMCID: PMC5701728.
    Citations: 12     
  23. Bao D, Upadhyayula S, Larsen JM, Xia B, Georgieva B, Nuñez V, Espinoza EM, Hartman JD, Wurch M, Chang A, Lin CK, Larkin J, Vasquez K, Beran GJ, Vullev VI. Dipole-mediated rectification of intramolecular photoinduced charge separation and charge recombination. J Am Chem Soc. 2014 Sep 17; 136(37):12966-73. PMID: 25162490.
    Citations: 7     Fields:    Translation:Cells
  24. Lock JY, Wyatt E, Upadhyayula S, Whall A, Nuñez V, Vullev VI, Liu H. Degradation and antibacterial properties of magnesium alloys in artificial urine for potential resorbable ureteral stent applications. J Biomed Mater Res A. 2014 Mar; 102(3):781-92. PMID: 23564415.
    Citations: 18     Fields:    Translation:HumansCells
  25. Nuñez V, Upadhyayula S, Millare B, Larsen JM, Hadian A, Shin S, Vandrangi P, Gupta S, Xu H, Lin AP, Georgiev GY, Vullev VI. Microfluidic space-domain time-resolved emission spectroscopy of terbium(III) and europium(III) chelates with pyridine-2,6-dicarboxylate. Anal Chem. 2013 May 07; 85(9):4567-77. PMID: 23550512.
    Citations: 2     Fields:    
  26. Xia B, Bao D, Upadhyayula S, Jones G, Vullev VI. Anthranilamides as bioinspired molecular electrets: experimental evidence for a permanent ground-state electric dipole moment. J Org Chem. 2013 Mar 01; 78(5):1994-2004. PMID: 23270467.
    Citations: 6     Fields:    
  27. Upadhyayula S, Quinata T, Bishop S, Gupta S, Johnson NR, Bahmani B, Bozhilov K, Stubbs J, Jreij P, Nallagatla P, Vullev VI. Coatings of polyethylene glycol for suppressing adhesion between solid microspheres and flat surfaces. Langmuir. 2012 Mar 20; 28(11):5059-69. PMID: 22364506.
    Citations: 9     Fields:    
  28. Lock JY, Draganov M, Whall A, Dhillon S, Upadhyayula S, Vullev VI, Liu H. Antimicrobial properties of biodegradable magnesium for next generation ureteral stent applications. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:1378-81. PMID: 23366156.
    Citations:    Fields:    Translation:HumansCells
  29. Upadhyayula S, Lam S, Ha A, Malik-Chaudhry HK, Vullev VI. Dynamic staining of Bacillus endospores with Thioflavin T. Annu Int Conf IEEE Eng Med Biol Soc. 2012; 2012:499-502. PMID: 23365938.
    Citations:    Fields:    Translation:Cells
  30. Upadhyayula S, Bao D, Millare B, Sylvia SS, Habib KM, Ashraf K, Ferreira A, Bishop S, Bonderer R, Baqai S, Jing X, Penchev M, Ozkan M, Ozkan CS, Lake RK, Vullev VI. Permanent electric dipole moments of carboxyamides in condensed media: what are the limitations of theory and experiment? J Phys Chem B. 2011 Aug 04; 115(30):9473-90. PMID: 21682315.
    Citations: 6     Fields:    
  31. Xia B, Upadhyayula S, Nuñez V, Landsman P, Lam S, Malik H, Gupta S, Sarshar M, Hu J, Anvari B, Jones G, Vullev VI. Amyloid histology stain for rapid bacterial endospore imaging. J Clin Microbiol. 2011 Aug; 49(8):2966-75. PMID: 21653779.
    Citations:    Fields:    Translation:Cells
  32. Bahmani B, Gupta S, Upadhyayula S, Vullev VI, Anvari B. Effect of polyethylene glycol coatings on uptake of indocyanine green loaded nanocapsules by human spleen macrophages in vitro. J Biomed Opt. 2011 May; 16(5):051303. PMID: 21639563.
    Citations: 14     Fields:    Translation:Cells
  33. Thomas MS, Nuñez V, Upadhyayula S, Zielins ER, Bao D, Vasquez JM, Bahmani B, Vullev VI. Kinetics of bacterial fluorescence staining with 3,3'-diethylthiacyanine. Langmuir. 2010 Jun 15; 26(12):9756-65. PMID: 20481488.
    Citations: 2     Fields:    Translation:Cells
  34. Bao D, Ramu S, Contreras A, Upadhyayula S, Vasquez JM, Beran G, Vullev VI. Electrochemical reduction of quinones: interfacing experiment and theory for defining effective radii of redox moieties. J Phys Chem B. 2010 Nov 18; 114(45):14467-79. PMID: 20527948.
    Citations: 8     Fields:    Translation:Cells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.