Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Alaattin Kaya, Ph.D.

Title
Institution
Department
Address
Phone

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Zhou X, Guang X, Sun D, Xu S, Li M, Seim I, Jie W, Yang L, Zhu Q, Xu J, Gao Q, Kaya A, Dou Q, Chen B, Ren W, Li S, Zhou K, Gladyshev VN, Nielsen R, Fang X, Yang G. Population genomics of finless porpoises reveal an incipient cetacean species adapted to freshwater. Nat Commun. 2018 04 10; 9(1):1276. PMID: 29636446.
    Citations:    Fields:    Translation:Animals
  2. Kaya A, Mariotti M, Gladyshev VN. Cytochrome c peroxidase facilitates the beneficial use of H2O2 in prokaryotes. Proc Natl Acad Sci U S A. 2017 08 15; 114(33):8678-8680. PMID: 28765365.
    Citations: 1     Fields:    Translation:Cells
  3. Lee SG, Kaya A, Avanesov AS, Podolskiy DI, Song EJ, Go DM, Jin GD, Hwang JY, Kim EB, Kim DY, Gladyshev VN. Age-associated molecular changes are deleterious and may modulate life span through diet. Sci Adv. 2017 Feb; 3(2):e1601833. PMID: 28232953.
    Citations: 2     Fields:    Translation:Animals
  4. Lee BC, Kaya A, Gladyshev VN. Methionine restriction and life-span control. Ann N Y Acad Sci. 2016 Jan; 1363:116-24. PMID: 26663138; PMCID: PMC5008916.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  5. Kaya A, Ma S, Wasko B, Lee M, Kaeberlein M, Gladyshev VN. Defining Molecular Basis for Longevity Traits in Natural Yeast Isolates. NPJ Aging Mech Dis. 2015; 1. PMID: 27030810.
    Citations: 3     
  6. Kaya A, Gerashchenko MV, Seim I, Labarre J, Toledano MB, Gladyshev VN. Adaptive aneuploidy protects against thiol peroxidase deficiency by increasing respiration via key mitochondrial proteins. Proc Natl Acad Sci U S A. 2015 Aug 25; 112(34):10685-90. PMID: 26261310; PMCID: PMC4553801.
    Citations: 13     Fields:    Translation:AnimalsCells
  7. Kaya A, Lee BC, Gladyshev VN. Regulation of protein function by reversible methionine oxidation and the role of selenoprotein MsrB1. Antioxid Redox Signal. 2015 Oct 01; 23(10):814-22. PMID: 26181576; PMCID: PMC4589106.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  8. Kaya A, Lobanov AV, Gladyshev VN. Evidence that mutation accumulation does not cause aging in Saccharomyces cerevisiae. Aging Cell. 2015 Jun; 14(3):366-71. PMID: 25702753; PMCID: PMC4406665.
    Citations: 16     Fields:    Translation:AnimalsCells
  9. Kaya A, Lobanov AV, Gerashchenko MV, Koren A, Fomenko DE, Koc A, Gladyshev VN. Thiol peroxidase deficiency leads to increased mutational load and decreased fitness in Saccharomyces cerevisiae. Genetics. 2014 Nov; 198(3):905-17. PMID: 25173844; PMCID: PMC4224179.
    Citations: 6     Fields:    Translation:AnimalsCells
  10. Lee BC, Kaya A, Ma S, Kim G, Gerashchenko MV, Yim SH, Hu Z, Harshman LG, Gladyshev VN. Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status. Nat Commun. 2014 Apr 07; 5:3592. PMID: 24710037; PMCID: PMC4350766.
    Citations: 35     Fields:    Translation:AnimalsCells
  11. Bozdag GO, Kaya A, Koc A, Noll GA, Prüfer D, Karakaya HC. Characterization of a cDNA from Beta maritima that confers nickel tolerance in yeast. Gene. 2014 Apr 01; 538(2):251-7. PMID: 24487090.
    Citations:    Fields:    Translation:AnimalsCells
  12. Labunskyy VM, Gerashchenko MV, Delaney JR, Kaya A, Kennedy BK, Kaeberlein M, Gladyshev VN. Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response. PLoS Genet. 2014 Jan; 10(1):e1004019. PMID: 24391512; PMCID: PMC3879150.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  13. Lee BC, Péterfi Z, Hoffmann FW, Moore RE, Kaya A, Avanesov A, Tarrago L, Zhou Y, Weerapana E, Fomenko DE, Hoffmann PR, Gladyshev VN. MsrB1 and MICALs regulate actin assembly and macrophage function via reversible stereoselective methionine oxidation. Mol Cell. 2013 Aug 08; 51(3):397-404. PMID: 23911929; PMCID: PMC4262529.
    Citations: 38     Fields:    Translation:AnimalsCells
  14. Le DT, Tarrago L, Watanabe Y, Kaya A, Lee BC, Tran U, Nishiyama R, Fomenko DE, Gladyshev VN, Tran LS. Diversity of plant methionine sulfoxide reductases B and evolution of a form specific for free methionine sulfoxide. PLoS One. 2013; 8(6):e65637. PMID: 23776515; PMCID: PMC3680461.
    Citations: 10     Fields:    Translation:AnimalsCells
  15. Liang X, Kaya A, Zhang Y, Le DT, Hua D, Gladyshev VN. Characterization of methionine oxidation and methionine sulfoxide reduction using methionine-rich cysteine-free proteins. BMC Biochem. 2012 Oct 23; 13:21. PMID: 23088625; PMCID: PMC3514235.
    Citations: 8     Fields:    Translation:AnimalsCells
  16. Tarrago L, Kaya A, Weerapana E, Marino SM, Gladyshev VN. Methionine sulfoxide reductases preferentially reduce unfolded oxidized proteins and protect cells from oxidative protein unfolding. J Biol Chem. 2012 Jul 13; 287(29):24448-59. PMID: 22628550; PMCID: PMC3397870.
    Citations: 23     Fields:    Translation:Cells
  17. Uluisik I, Kaya A, Fomenko DE, Karakaya HC, Carlson BA, Gladyshev VN, Koc A. Boron stress activates the general amino acid control mechanism and inhibits protein synthesis. PLoS One. 2011; 6(11):e27772. PMID: 22114689; PMCID: PMC3219688.
    Citations: 5     Fields:    Translation:AnimalsCells
  18. Lee BC, Lobanov AV, Marino SM, Kaya A, Seravalli J, Hatfield DL, Gladyshev VN. A 4-selenocysteine, 2-selenocysteine insertion sequence (SECIS) element methionine sulfoxide reductase from Metridium senile reveals a non-catalytic function of selenocysteines. J Biol Chem. 2011 May 27; 286(21):18747-55. PMID: 21393246; PMCID: PMC3099691.
    Citations: 8     Fields:    Translation:AnimalsCells
  19. Fomenko DE, Koc A, Agisheva N, Jacobsen M, Kaya A, Malinouski M, Rutherford JC, Siu KL, Jin DY, Winge DR, Gladyshev VN. Thiol peroxidases mediate specific genome-wide regulation of gene expression in response to hydrogen peroxide. Proc Natl Acad Sci U S A. 2011 Feb 15; 108(7):2729-34. PMID: 21282621; PMCID: PMC3041109.
    Citations: 48     Fields:    Translation:AnimalsCells
  20. Uluisik I, Kaya A, Unlu ES, Avsar K, Karakaya HC, Yalcin T, Koc A. Genome-wide identification of genes that play a role in boron stress response in yeast. Genomics. 2011 Feb; 97(2):106-11. PMID: 21035538.
    Citations: 3     Fields:    Translation:AnimalsCells
  21. Kaya A, Koc A, Lee BC, Fomenko DE, Rederstorff M, Krol A, Lescure A, Gladyshev VN. Compartmentalization and regulation of mitochondrial function by methionine sulfoxide reductases in yeast. Biochemistry. 2010 Oct 05; 49(39):8618-25. PMID: 20799725; PMCID: PMC3061818.
    Citations: 7     Fields:    Translation:AnimalsCells
  22. Liang X, Fomenko DE, Hua D, Kaya A, Gladyshev VN. Diversity of protein and mRNA forms of mammalian methionine sulfoxide reductase B1 due to intronization and protein processing. PLoS One. 2010 Jul 09; 5(7):e11497. PMID: 20634897; PMCID: PMC2901347.
    Citations: 2     Fields:    Translation:AnimalsCells
  23. Kaya A, Karakaya HC, Fomenko DE, Gladyshev VN, Koc A. Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast. Mol Cell Biol. 2009 Jul; 29(13):3665-74. PMID: 19414602; PMCID: PMC2698749.
    Citations: 16     Fields:    Translation:AnimalsCells
  24. Le DT, Lee BC, Marino SM, Zhang Y, Fomenko DE, Kaya A, Hacioglu E, Kwak GH, Koc A, Kim HY, Gladyshev VN. Functional analysis of free methionine-R-sulfoxide reductase from Saccharomyces cerevisiae. J Biol Chem. 2009 Feb 13; 284(7):4354-64. PMID: 19049972; PMCID: PMC2640979.
    Citations: 28     Fields:    Translation:AnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Kaya's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (163)
Explore
_
Co-Authors (6)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.