Harvard Catalyst Profiles

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Raghu Ram Chivukula, M.D.,Ph.D.

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Biography
Johns Hopkins University, Baltimore, MDBANeuroscience
Johns Hopkins University, Baltimore, MDMDMedicine
Johns Hopkins University, Baltimore, MDPhDHuman Genetics
Massachusetts General Hospital, Boston, MAInternal Medicine
Harvard Medical School, Boston, MAPulmonary & Critical Care Medicine
2014 - 2014
Forbes 30 Under 30 in Science and Healthcare
2013 - 2013
Michael A. Shanoff Research Award
2013
Alpha Omega Alpha
2013 - 2013
William Stewart Halsted Award
2006 - 2013
Medical Scientist Training Program
2004
Phi Beta Kappa

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Waghray A, Tata PR, Selig MK, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. A Conserved Distal Lung Regenerative Pathway in Acute Lung Injury. Am J Pathol. 2018 05; 188(5):1149-1160. PMID: 29476724.
    Citations:    Fields:    
  2. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Tata PR, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. Delayed Alveolar Epithelialization: A Distinct Pathology in Diffuse Acute Lung Injury. Am J Respir Crit Care Med. 2018 Feb 15; 197(4):522-524. PMID: 28696778.
    Citations: 1     Fields:    
  3. Knabel MK, Ramachandran K, Karhadkar S, Hwang HW, Creamer TJ, Chivukula RR, Sheikh F, Clark KR, Torbenson M, Montgomery RA, Cameron AM, Mendell JT, Warren DS. Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. PLoS One. 2015; 10(4):e0124411. PMID: 25923107.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  4. Zeitels LR, Acharya A, Shi G, Chivukula D, Chivukula RR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Richardson JA, Mendell JT. Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes Dev. 2014 Dec 01; 28(23):2585-90. PMID: 25395662.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  5. Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Maitra A, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 2014 May 22; 157(5):1104-16. PMID: 24855947.
    Citations: 47     Fields:    Translation:HumansAnimalsCells
  6. Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, Jacob ST, Mendell JT, Ghoshal K. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest. 2012 Aug; 122(8):2871-83. PMID: 22820288.
    Citations: 207     Fields:    Translation:HumansAnimalsCells
  7. Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Mol Cancer Ther. 2011 Aug; 10(8):1470-80. PMID: 21622730.
    Citations: 101     Fields:    Translation:HumansAnimalsCells
  8. Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev. 2010 Dec 15; 24(24):2754-9. PMID: 21159816.
    Citations: 116     Fields:    Translation:HumansAnimalsCells
  9. Persat A, Chivukula RR, Mendell JT, Santiago JG. Quantification of global microRNA abundance by selective isotachophoresis. Anal Chem. 2010 Dec 01; 82(23):9631-5. PMID: 21062022.
    Citations: 1     Fields:    
  10. Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 2009 Jun 12; 137(6):1005-17. PMID: 19524505.
    Citations: 602     Fields:    Translation:AnimalsCells
  11. Chivukula RR, Mendell JT. Abate and switch: miR-145 in stem cell differentiation. Cell. 2009 May 15; 137(4):606-8. PMID: 19450510.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  12. Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3384-9. PMID: 19211792.
    Citations: 159     Fields:    Translation:HumansCells
  13. Allen G, Simpkins CE, Segev D, Warren D, King K, Taube J, Locke J, Baldwin W, Haas M, Chivukula R, Montgomery RA. Rapid accomodation of an A1 renal allograft after preconditioning for ABO-incompatible transplantation. Contrib Nephrol. 2009; 162:35-46. PMID: 19001812.
    Citations: 2     Fields:    Translation:Humans
  14. Chivukula RR, Mendell JT. Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci. 2008 Oct; 33(10):474-81. PMID: 18774719.
    Citations: 43     Fields:    Translation:HumansAnimals
  15. Soderlund KA, Chivukula RR, Russell SD, Conte JV, Mudd JO, Halushka MK. Prognostic value of left ventricular apical tissue removed for HeartMate II left ventricular assist device placement. Cardiovasc Pathol. 2009 Jul-Aug; 18(4):217-22. PMID: 18706833.
    Citations: 2     Fields:    Translation:Humans
  16. Chaudhury S, Eisinger JM, Hao L, Hicks J, Chivukula R, Turano KA. Visual illusion in virtual world alters women's target-directed walking. Exp Brain Res. 2004 Dec; 159(3):360-9. PMID: 15243729.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH/NCATS Clinical and Translational Science Award (CTSA) program, grant number UL1TR001102, and through institutional support from Harvard University, Harvard Medical School, Harvard T.H. Chan School of Public Health, Beth Israel Deaconess Medical Center, Boston Children's Hospital, Brigham and Women's Hospital, Massachusetts General Hospital and the Dana Farber Cancer Institute.