Harvard Catalyst Profiles

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Raghu Ram Chivukula, M.D.,Ph.D.

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Johns Hopkins University, Baltimore, MDBANeuroscience
Johns Hopkins University, Baltimore, MDMDMedicine
Johns Hopkins University, Baltimore, MDPhDHuman Genetics
Massachusetts General Hospital, Boston, MAInternal Medicine
Harvard Medical School, Boston, MAPulmonary & Critical Care Medicine
2020 - 2023
Parker B. Francis Foundation Fellow
2014 - 2014
Forbes 30 Under 30 in Science and Healthcare
2013 - 2013
Michael A. Shanoff Research Award
Alpha Omega Alpha
2013 - 2013
William Stewart Halsted Award
2006 - 2013
Medical Scientist Training Program
Phi Beta Kappa

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Chivukula RR, Maley JH, Dudzinski DM, Hibbert K, Hardin CC. Evidence-Based Management of the Critically Ill Adult With SARS-CoV-2 Infection. J Intensive Care Med. 2021 Jan; 36(1):18-41. PMID: 33111601.
    Citations:    Fields:    Translation:Humans
  2. Hariri LP, North CM, Shih AR, Israel RA, Maley JH, Villalba JA, Vinarsky V, Rubin J, Okin DA, Sclafani A, Alladina JW, Griffith JW, Gillette MA, Raz Y, Richards CJ, Wong AK, Ly A, Hung YP, Chivukula RR, Petri CR, Calhoun TF, Brenner LN, Hibbert KA, Medoff BD, Hardin CC, Stone JR, Mino-Kenudson M. Lung Histopathology in Coronavirus Disease 2019 as Compared With Severe Acute Respiratory Sydrome and H1N1 Influenza: A Systematic Review. Chest. 2021 01; 159(1):73-84. PMID: 33038391.
    Citations: 10     Fields:    Translation:HumansCells
  3. Petri CR, Brenner LN, Calhoun TF, Chivukula RR, Maley JH, Vinarsky V, Dudzinski DM, Hardin CC. The Fast Literature Assessment and Review (FLARE) Initiative. A Collaborative Effort for Timely Literature Appraisal during the Coronavirus Disease Pandemic. ATS Sch. 2020 Jun 29; 1(2):186-193. PMID: 33870283.
  4. Maley JH, Petri CR, Brenner LN, Chivukula RR, Calhoun TF, Vinarsky V, Hardin CC. Anticoagulation, immortality, and observations of COVID-19. Res Pract Thromb Haemost. 2020 Jul; 4(5):674-676. PMID: 32685874.
    Citations: 1     
  5. Shamseldin HE, Al Mogarri I, Alqwaiee MM, Alharbi AS, Baqais K, AlSaadi M, AlAnzi T, Alhashem A, Saghier A, Ameen W, Ibrahim N, Yang J, Abdulwahab F, Hashem M, Chivukula RR, Alkuraya FS. An exome-first approach to aid in the diagnosis of primary ciliary dyskinesia. Hum Genet. 2020 Oct; 139(10):1273-1283. PMID: 32367404.
    Citations:    Fields:    Translation:HumansCells
  6. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. Author Correction: A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 Feb; 26(2):300. PMID: 31996837.
    Citations: 2     Fields:    
  7. Chivukula RR, Montoro DT, Leung HM, Yang J, Shamseldin HE, Taylor MS, Dougherty GW, Zariwala MA, Carson J, Daniels MLA, Sears PR, Black KE, Hariri LP, Almogarri I, Frenkel EM, Vinarsky V, Omran H, Knowles MR, Tearney GJ, Alkuraya FS, Sabatini DM. A human ciliopathy reveals essential functions for NEK10 in airway mucociliary clearance. Nat Med. 2020 02; 26(2):244-251. PMID: 31959991.
    Citations: 5     Fields:    Translation:HumansCells
  8. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Waghray A, Tata PR, Selig MK, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. A Conserved Distal Lung Regenerative Pathway in Acute Lung Injury. Am J Pathol. 2018 05; 188(5):1149-1160. PMID: 29476724.
    Citations: 7     Fields:    Translation:Humans
  9. Taylor MS, Chivukula RR, Myers LC, Jeck WR, Tata PR, O'Donnell WJ, Farver CF, Thompson BT, Rajagopal J, Kradin RL. Delayed Alveolar Epithelialization: A Distinct Pathology in Diffuse Acute Lung Injury. Am J Respir Crit Care Med. 2018 02 15; 197(4):522-524. PMID: 28696778.
    Citations: 3     Fields:    Translation:Humans
  10. Knabel MK, Ramachandran K, Karhadkar S, Hwang HW, Creamer TJ, Chivukula RR, Sheikh F, Clark KR, Torbenson M, Montgomery RA, Cameron AM, Mendell JT, Warren DS. Systemic Delivery of scAAV8-Encoded MiR-29a Ameliorates Hepatic Fibrosis in Carbon Tetrachloride-Treated Mice. PLoS One. 2015; 10(4):e0124411. PMID: 25923107.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  11. Zeitels LR, Acharya A, Shi G, Chivukula D, Chivukula RR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Richardson JA, Mendell JT. Tumor suppression by miR-26 overrides potential oncogenic activity in intestinal tumorigenesis. Genes Dev. 2014 Dec 01; 28(23):2585-90. PMID: 25395662.
    Citations: 25     Fields:    Translation:HumansAnimalsCells
  12. Chivukula RR, Shi G, Acharya A, Mills EW, Zeitels LR, Anandam JL, Abdelnaby AA, Balch GC, Mansour JC, Yopp AC, Maitra A, Mendell JT. An essential mesenchymal function for miR-143/145 in intestinal epithelial regeneration. Cell. 2014 May 22; 157(5):1104-16. PMID: 24855947.
    Citations: 68     Fields:    Translation:HumansAnimalsCells
  13. Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, Jacob ST, Mendell JT, Ghoshal K. Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver. J Clin Invest. 2012 Aug; 122(8):2871-83. PMID: 22820288.
    Citations: 287     Fields:    Translation:HumansAnimalsCells
  14. Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A. Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. . 2011 Aug; 10(8):1470-80. PMID: 21622730.
    Citations: 123     Translation:HumansAnimalsCells
  15. Kent OA, Chivukula RR, Mullendore M, Wentzel EA, Feldmann G, Lee KH, Liu S, Leach SD, Maitra A, Mendell JT. Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway. Genes Dev. 2010 Dec 15; 24(24):2754-9. PMID: 21159816.
    Citations: 148     Fields:    Translation:HumansAnimalsCells
  16. Persat A, Chivukula RR, Mendell JT, Santiago JG. Quantification of global microRNA abundance by selective isotachophoresis. Anal Chem. 2010 Dec 01; 82(23):9631-5. PMID: 21062022.
    Citations: 2     Fields:    
  17. Kota J, Chivukula RR, O'Donnell KA, Wentzel EA, Montgomery CL, Hwang HW, Chang TC, Vivekanandan P, Torbenson M, Clark KR, Mendell JR, Mendell JT. Therapeutic microRNA delivery suppresses tumorigenesis in a murine liver cancer model. Cell. 2009 Jun 12; 137(6):1005-17. PMID: 19524505.
    Citations: 700     Fields:    Translation:AnimalsCells
  18. Chivukula RR, Mendell JT. Abate and switch: miR-145 in stem cell differentiation. Cell. 2009 May 15; 137(4):606-8. PMID: 19450510.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  19. Chang TC, Zeitels LR, Hwang HW, Chivukula RR, Wentzel EA, Dews M, Jung J, Gao P, Dang CV, Beer MA, Thomas-Tikhonenko A, Mendell JT. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation. Proc Natl Acad Sci U S A. 2009 Mar 03; 106(9):3384-9. PMID: 19211792.
    Citations: 185     Fields:    Translation:HumansCells
  20. Allen G, Simpkins CE, Segev D, Warren D, King K, Taube J, Locke J, Baldwin W, Haas M, Chivukula R, Montgomery RA. Rapid accomodation of an A1 renal allograft after preconditioning for ABO-incompatible transplantation. Contrib Nephrol. 2009; 162:35-46. PMID: 19001812.
    Citations: 2     Fields:    Translation:Humans
  21. Chivukula RR, Mendell JT. Circular reasoning: microRNAs and cell-cycle control. Trends Biochem Sci. 2008 Oct; 33(10):474-81. PMID: 18774719.
    Citations: 47     Fields:    Translation:HumansAnimals
  22. Soderlund KA, Chivukula RR, Russell SD, Conte JV, Mudd JO, Halushka MK. Prognostic value of left ventricular apical tissue removed for HeartMate II left ventricular assist device placement. Cardiovasc Pathol. 2009 Jul-Aug; 18(4):217-22. PMID: 18706833.
    Citations: 2     Fields:    Translation:Humans
  23. Chaudhury S, Eisinger JM, Hao L, Hicks J, Chivukula R, Turano KA. Visual illusion in virtual world alters women's target-directed walking. Exp Brain Res. 2004 Dec; 159(3):360-9. PMID: 15243729.
    Citations: 4     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.