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James Walter Luccarelli

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Peacock H, Henriques ST, Benfield AH, Elliott AG, Luo J, Luccarelli J, Nagano M, Craik DJ, Hamilton AD. Antimicrobial peptide mimetics based on a diphenylacetylene scaffold: synthesis, conformational analysis and activity. ChemMedChem. 2020 Aug 04. PMID: 32754982.
    Citations:    
  2. Luccarelli J, Fernandez-Robles C, Fernandez-Robles C, Horvath RJ, Berg S, McCoy TH, Seiner SJ, Henry ME. Modified Anesthesia Protocol for Electroconvulsive Therapy Permits Reduction in Aerosol-Generating Bag-Mask Ventilation during the COVID-19 Pandemic. Psychother Psychosom. 2020 Jun 18; 1-6. PMID: 32554959.
    Citations:    
  3. Luccarelli J, Henry ME, McCoy TH. Demographics of Patients Receiving Electroconvulsive Therapy Based on State-Mandated Reporting Data. J ECT. 2020 May 22. PMID: 32453188.
    Citations:    
  4. Harvey EP, Hauseman ZJ, Cohen DT, Rettenmaier TJ, Lee S, Huhn AJ, Wales TE, Seo HS, Luccarelli J, Newman CE, Guerra RM, Bird GH, Dhe-Paganon S, Engen JR, Wells JA, Walensky LD. Identification of a Covalent Molecular Inhibitor of Anti-apoptotic BFL-1 by Disulfide Tethering. Cell Chem Biol. 2020 Jun 18; 27(6):647-656.e6. PMID: 32413285.
    Citations:    
  5. Luccarelli J, McCoy TH, Seiner SJ, Henry ME. Maintenance ECT is associated with sustained improvement in depression symptoms without adverse cognitive effects in a retrospective cohort of 100 patients each receiving 50 or more ECT treatments. J Affect Disord. 2020 Jun 15; 271:109-114. PMID: 32479305.
    Citations:    
  6. Luccarelli J, Henry ME, McCoy TH. Quantification of fracture rate during electroconvulsive therapy (ECT) using state-mandated reporting data. Brain Stimul. 2020 May - Jun; 13(3):523-524. PMID: 32289667.
    Citations:    
  7. Luccarelli J, Fernandez-Robles C, Berg SM, Henry ME. Bilateral Forearm Fractures During Modified Electroconvulsive Therapy in a Male Patient With a History of Hyperparathyroidism and Elevated Pseudocholinesterase Activity. J ECT. 2019 09; 35(3):e35-e36. PMID: 31094876.
    Citations:    
  8. Luccarelli J, Paton RS. Hydrogen-Bond-Dependent Conformational Switching: A Computational Challenge from Experimental Thermochemistry. J Org Chem. 2019 01 18; 84(2):613-621. PMID: 30586500.
    Citations:    Fields:    
  9. Escudero S, Zaganjor E, Lee S, Mill CP, Morgan AM, Crawford EB, Chen J, Wales TE, Mourtada R, Luccarelli J, Bird GH, Steidl U, Engen JR, Haigis MC, Opferman JT, Walensky LD. Dynamic Regulation of Long-Chain Fatty Acid Oxidation by a Noncanonical Interaction between the MCL-1 BH3 Helix and VLCAD. Mol Cell. 2018 03 01; 69(5):729-743.e7. PMID: 29499131.
    Citations: 1     Fields:    Translation:AnimalsCells
  10. Luccarelli J, Jones IM, Thompson S, Hamilton AD. Unpicking the determinants of amide NHO[double bond, length as m-dash]C hydrogen bond strength with diphenylacetylene molecular balances. Org Biomol Chem. 2017 Nov 07; 15(43):9156-9163. PMID: 29058730.
    Citations:    Fields:    
  11. Pritz JR, Wachter F, Lee S, Luccarelli J, Wales TE, Cohen DT, Coote P, Heffron GJ, Engen JR, Massefski W, Walensky LD. Allosteric sensitization of proapoptotic BAX. Nat Chem Biol. 2017 Sep; 13(9):961-967. PMID: 28692068.
    Citations: 5     Fields:    Translation:HumansCells
  12. Peacock H, Luo J, Yamashita T, Luccarelli J, Thompson S, Hamilton AD. Non-covalent S···O interactions control conformation in a scaffold that disrupts islet amyloid polypeptide fibrillation. Chem Sci. 2016 Oct 01; 7(10):6435-6439. PMID: 28451100.
    Citations: 1     
  13. Lee S, Wales TE, Escudero S, Cohen DT, Luccarelli J, Gallagher CG, Cohen NA, Huhn AJ, Bird GH, Engen JR, Walensky LD. Allosteric inhibition of antiapoptotic MCL-1. Nat Struct Mol Biol. 2016 06; 23(6):600-7. PMID: 27159560.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  14. Edwards AL, Wachter F, Lammert M, Huhn AJ, Luccarelli J, Bird GH, Walensky LD. Cellular Uptake and Ultrastructural Localization Underlie the Pro-apoptotic Activity of a Hydrocarbon-stapled BIM BH3 Peptide. ACS Chem Biol. 2015 Sep 18; 10(9):2149-57. PMID: 26151238.
    Citations: 9     Fields:    Translation:AnimalsCells
  15. Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices. Proc Natl Acad Sci U S A. 2015 Feb 10; 112(6):1761-6. PMID: 25624485.
    Citations: 22     Fields:    Translation:HumansAnimalsCells
  16. Simister PC, Luccarelli J, Thompson S, Appella DH, Feller SM, Hamilton AD. Novel inhibitors of a Grb2 SH3C domain interaction identified by a virtual screen. Bioorg Med Chem. 2013 Jul 15; 21(14):4027-33. PMID: 23182216.
    Citations: 1     Fields:    Translation:HumansCells
  17. Luccarelli J, Michel J, Tirado-Rives J, Jorgensen WL. Effects of Water Placement on Predictions of Binding Affinities for p38a MAP Kinase Inhibitors. J Chem Theory Comput. 2010 Jan 01; 6(12):3850-3856. PMID: 21278915.
    Citations: 18     Fields:    
  18. Schmitz Y, Luccarelli J, Kim M, Wang M, Sulzer D. Glutamate controls growth rate and branching of dopaminergic axons. J Neurosci. 2009 Sep 23; 29(38):11973-81. PMID: 19776283.
    Citations: 23     Fields:    Translation:AnimalsCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.