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Ravi Jasuja, Ph.D.

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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. 1 R33 AG068234-01 (Jasuja, Ravi) Sep 1, 2020 - May 31, 2024
    Characterizing novel nano-formulation for sustained delivery of hormones
    Role: PI
  2. 3P30AG03167910S3 (Ravi Jasuja) Sep 1, 2020 - May 31, 2022
    Transforming Predictive Data into Proactive Care for COVID-19
    Role: PI
  3. R44G045011 (JASUJA, RAVI) Sep 15, 2017 - May 31, 2022
    Phase II: Research and Commercialization of TruT Algorithm
    Role: Principal Investigator
  4. R43AG045011 (JASUJA, RAVI) Sep 15, 2014 - Aug 31, 2015
    Novel Algorithm for Free Testosterone Determination
    Role: Principal Investigator
  5. P30AG031679 (BHASIN, SHALENDER) Sep 1, 2008 - Jun 30, 2026
    Boston OAIC: A Translational Approach to Function Promoting Therapies
    Role: Co-Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Song W, Zhang L, Liu L, Sainlaire M, Karvar M, Kang MJ, Pullman A, Lipsitz S, Massaro A, Patil N, Jasuja R, Dykes PC. Predicting Hospitalization of COVID-19 Positive Patients Using Clinician-guided Machine Learning Methods. J Am Med Inform Assoc. 2022 May 20. PMID: 35595237.
    Citations:    Fields:    
  2. Peng L, Gagliano-Jucá T, Pencina KM, Krishnan S, Li Z, Tracy RP, Jasuja R, Bhasin S. Age Trends in Growth and Differentiation Factor-11 and Myostatin Levels in Healthy Men, and Differential Response to Testosterone, Measured Using Liquid Chromatography-Tandem Mass Spectrometry. J Gerontol A Biol Sci Med Sci. 2022 04 01; 77(4):763-769. PMID: 34037752.
    Citations: 2     Fields:    Translation:Humans
  3. Jasuja R, Pencina KM, Peng L, Bhasin S. Accurate Measurement and Harmonized Reference Ranges for Total and Free Testosterone Levels. Endocrinol Metab Clin North Am. 2022 03; 51(1):63-75. PMID: 35216721.
    Citations:    Fields:    Translation:Humans
  4. Jasuja R, Spencer D, Jayaraj A, Peng L, Krishna M, Lawney B, Patel P, Jayaram B, Thayer KM, Beveridge DL, Bhasin S. Estradiol induces allosteric coupling and partitioning of sex-hormone-binding globulin monomers among conformational states. iScience. 2021 Jun 25; 24(6):102414. PMID: 34041454.
  5. Jayaraj A, Schwanz HA, Spencer DJ, Bhasin S, Hamilton JA, Jayaram B, Goldman AL, Krishna M, Krishnan M, Shah A, Jin Z, Krenzel E, Nair SN, Ramesh S, Guo W, Wagner G, Arthanari H, Peng L, Lawney B, Jasuja R. Allosterically Coupled Multisite Binding of Testosterone to Human Serum Albumin. Endocrinology. 2021 02 01; 162(2). PMID: 33125473.
    Citations: 2     Fields:    Translation:Cells
  6. Holmboe SA, Jasuja R, Lawney B, Priskorn L, Joergensen N, Linneberg A, Jensen TK, Skakkebæk NE, Juul A, Andersson AM. Free testosterone and cardiometabolic parameters in men: comparison of algorithms. Endocr Connect. 2021 Feb; 10(2):220-229. PMID: 33544092.
  7. Endo Y, Baldino K, Li B, Zhang Y, Sakthivel D, MacArthur M, Panayi AC, Kip P, Spencer DJ, Jasuja R, Bagchi D, Bhasin S, Nuutila K, Neppl RL, Wagers AJ, Sinha I. Loss of ARNT in skeletal muscle limits muscle regeneration in aging. FASEB J. 2020 12; 34(12):16086-16104. PMID: 33064329.
    Citations: 3     Fields:    Translation:AnimalsCells
  8. Cortés YI, Barinas-Mitchell E, Suder Egnot N, Bhasin S, Jasuja R, Santoro N, Thurston RC. Associations of Endogenous Sex Hormones with Carotid Plaque Burden and Characteristics in Midlife Women. J Clin Endocrinol Metab. 2020 04 01; 105(4). PMID: 31900485.
    Citations: 1     Fields:    Translation:Humans
  9. Fielding RA, Reeves AR, Jasuja R, Liu C, Barrett BB, Lustgarten MS. Muscle strength is increased in mice that are colonized with microbiota from high-functioning older adults. Exp Gerontol. 2019 11; 127:110722. PMID: 31493521.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  10. Tapper J, Arver S, Holm T, Bottai M, Machado M, Jasuja R, Martling A, Buchli C. Acute primary testicular failure due to radiotherapy increases risk of severe postoperative adverse events in rectal cancer patients. Eur J Surg Oncol. 2020 01; 46(1):98-104. PMID: 31350073.
    Citations:    Fields:    Translation:Humans
  11. Thurston RC, Bhasin S, Chang Y, Barinas-Mitchell E, Matthews KA, Jasuja R, Santoro N. Reproductive Hormones and Subclinical Cardiovascular Disease in Midlife Women. J Clin Endocrinol Metab. 2018 08 01; 103(8):3070-3077. PMID: 29788255.
    Citations: 7     Fields:    Translation:Humans
  12. Guo W, Pencina KM, Gagliano-Jucá T, Jasuja R, Morris N, O'Connell KE, Westmoreland S, Bhasin S. Effects of an ActRIIB.Fc Ligand Trap on Cardiac Function in Simian Immunodeficiency Virus-Infected Male Rhesus Macaques. J Endocr Soc. 2018 Aug 01; 2(8):817-831. PMID: 30019021.
    Citations: 2     
  13. Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Ramachandran V, Carter E, Wu F, Jasuja R. Corrigendum to "A multi-step, allosteric model of testosterone's binding to sex hormone binding globulin" [Mol. Cell. Endocrinol. 399 (2015) 190-200]. Mol Cell Endocrinol. 2017 10 15; 454:167. PMID: 28780939.
    Citations:    Fields:    
  14. Goldman AL, Bhasin S, Wu FCW, Krishna M, Matsumoto AM, Jasuja R. A Reappraisal of Testosterone's Binding in Circulation: Physiological and Clinical Implications. Endocr Rev. 2017 08 01; 38(4):302-324. PMID: 28673039.
    Citations: 54     Fields:    Translation:Humans
  15. Basaria S, Jasuja R, Huang G, Wharton W, Pan H, Pencina K, Li Z, Travison TG, Bhawan J, Gonthier R, Labrie F, Dury AY, Serra C, Papazian A, O'Leary M, Amr S, Storer TW, Stern E, Bhasin S. Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss. J Clin Endocrinol Metab. 2016 12; 101(12):4669-4680. PMID: 27662439.
    Citations: 17     Fields:    Translation:Humans
  16. Guo W, Miller AD, Pencina K, Wong S, Lee A, Yee M, Toraldo G, Jasuja R, Bhasin S. Joint dysfunction and functional decline in middle age myostatin null mice. Bone. 2016 Feb; 83:141-148. PMID: 26549246.
    Citations: 3     Fields:    Translation:Animals
  17. Jang H, Bhasin S, Guarneri T, Serra C, Schneider M, Lee MJ, Guo W, Fried SK, Pencina K, Jasuja R. The Effects of a Single Developmentally Entrained Pulse of Testosterone in Female Neonatal Mice on Reproductive and Metabolic Functions in Adult Life. Endocrinology. 2015 Oct; 156(10):3737-46. PMID: 26132920.
    Citations: 7     Fields:    Translation:Animals
  18. Guo W, Bachman E, Vogel J, Li M, Peng L, Pencina K, Serra C, Sandor NL, Jasuja R, Montano M, Basaria S, Gassmann M, Bhasin S. The effects of short-term and long-term testosterone supplementation on blood viscosity and erythrocyte deformability in healthy adult mice. Endocrinology. 2015 May; 156(5):1623-9. PMID: 25774550.
    Citations: 8     Fields:    Translation:AnimalsCells
  19. Jasuja R, LeBrasseur NK. Regenerating skeletal muscle in the face of aging and disease. Am J Phys Med Rehabil. 2014 Nov; 93(11 Suppl 3):S88-96. PMID: 24879554.
    Citations: 9     Fields:    Translation:Humans
  20. Zakharov MN, Bhasin S, Travison TG, Xue R, Ulloor J, Vasan RS, Carter E, Wu F, Jasuja R. A multi-step, dynamic allosteric model of testosterone's binding to sex hormone binding globulin. Mol Cell Endocrinol. 2015 Jan 05; 399:190-200. PMID: 25240469.
    Citations: 16     Fields:    Translation:HumansCells
  21. Xue R, Zakharov MN, Xia Y, Bhasin S, Costello JC, Jasuja R. Research resource: EPSLiM: ensemble predictor for short linear motifs in nuclear hormone receptors. Mol Endocrinol. 2014 May; 28(5):768-77. PMID: 24678734.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  22. Jasuja R, Costello JC, Singh R, Gupta V, Spina CS, Toraldo G, Jang H, Li H, Serra C, Guo W, Chauhan P, Narula NS, Guarneri T, Ergun A, Travison TG, Collins JJ, Bhasin S. Combined administration of testosterone plus an ornithine decarboxylase inhibitor as a selective prostate-sparing anabolic therapy. Aging Cell. 2014 Apr; 13(2):303-10. PMID: 24305501.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  23. Serra C, Sandor NL, Jang H, Lee D, Toraldo G, Guarneri T, Wong S, Zhang A, Guo W, Jasuja R, Bhasin S. The effects of testosterone deprivation and supplementation on proteasomal and autophagy activity in the skeletal muscle of the male mouse: differential effects on high-androgen responder and low-androgen responder muscle groups. Endocrinology. 2013 Dec; 154(12):4594-606. PMID: 24105483.
    Citations: 23     Fields:    Translation:Animals
  24. DeFuria J, Belkina AC, Jagannathan-Bogdan M, Snyder-Cappione J, Carr JD, Nersesova YR, Markham D, Strissel KJ, Watkins AA, Zhu M, Allen J, Bouchard J, Toraldo G, Jasuja R, Obin MS, McDonnell ME, Apovian C, Denis GV, Nikolajczyk BS. B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile. Proc Natl Acad Sci U S A. 2013 Mar 26; 110(13):5133-8. PMID: 23479618.
    Citations: 206     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
  25. Guo W, Bachman E, Li M, Roy CN, Blusztajn J, Wong S, Chan SY, Serra C, Jasuja R, Travison TG, Muckenthaler MU, Nemeth E, Bhasin S. Testosterone administration inhibits hepcidin transcription and is associated with increased iron incorporation into red blood cells. Aging Cell. 2013 Apr; 12(2):280-91. PMID: 23399021.
    Citations: 58     Fields:    Translation:HumansAnimalsCells
  26. Guo W, Wong S, Li M, Liang W, Liesa M, Serra C, Jasuja R, Bartke A, Kirkland JL, Shirihai O, Bhasin S. Testosterone plus low-intensity physical training in late life improves functional performance, skeletal muscle mitochondrial biogenesis, and mitochondrial quality control in male mice. PLoS One. 2012; 7(12):e51180. PMID: 23240002.
    Citations: 20     Fields:    Translation:HumansAnimalsCells
  27. Alamdari N, Toraldo G, Aversa Z, Smith I, Castillero E, Renaud G, Qaisar R, Larsson L, Jasuja R, Hasselgren PO. Loss of muscle strength during sepsis is in part regulated by glucocorticoids and is associated with reduced muscle fiber stiffness. Am J Physiol Regul Integr Comp Physiol. 2012 Nov 15; 303(10):R1090-9. PMID: 23019215.
    Citations: 10     Fields:    Translation:AnimalsCells
  28. Serra C, Tangherlini F, Rudy S, Lee D, Toraldo G, Sandor NL, Zhang A, Jasuja R, Bhasin S. Testosterone improves the regeneration of old and young mouse skeletal muscle. J Gerontol A Biol Sci Med Sci. 2013 Jan; 68(1):17-26. PMID: 22499765.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  29. Toraldo G, Bhasin S, Bakhit M, Guo W, Serra C, Safer JD, Bhawan J, Jasuja R. Topical androgen antagonism promotes cutaneous wound healing without systemic androgen deprivation by blocking ß-catenin nuclear translocation and cross-talk with TGF-ß signaling in keratinocytes. Wound Repair Regen. 2012 Jan-Feb; 20(1):61-73. PMID: 22276587.
    Citations: 7     Fields:    Translation:AnimalsCells
  30. Braga M, Bhasin S, Jasuja R, Pervin S, Singh R. Testosterone inhibits transforming growth factor-ß signaling during myogenic differentiation and proliferation of mouse satellite cells: potential role of follistatin in mediating testosterone action. Mol Cell Endocrinol. 2012 Mar 05; 350(1):39-52. PMID: 22138414.
    Citations: 33     Fields:    Translation:AnimalsCells
  31. Ward JE, Ren R, Toraldo G, Soohoo P, Guan J, O'Hara C, Jasuja R, Trinkaus-Randall V, Liao R, Connors LH, Seldin DC. Doxycycline reduces fibril formation in a transgenic mouse model of AL amyloidosis. Blood. 2011 Dec 15; 118(25):6610-7. PMID: 21998211.
    Citations: 50     Fields:    Translation:HumansAnimalsCells
  32. Kumar R, Zakharov MN, Khan SH, Miki R, Jang H, Toraldo G, Singh R, Bhasin S, Jasuja R. The dynamic structure of the estrogen receptor. J Amino Acids. 2011; 2011:812540. PMID: 22312471.
    Citations: 59     
  33. Bhasin S, Jasuja R, Tu P, Storer TW, Guo W. Novel strategies for improving physical function. Horm Res Paediatr. 2011; 76 Suppl 1:17-23. PMID: 21778743.
    Citations:    Fields:    Translation:HumansAnimals
  34. Cacicedo JM, Gauthier MS, Lebrasseur NK, Jasuja R, Ruderman NB, Ido Y. Acute exercise activates AMPK and eNOS in the mouse aorta. Am J Physiol Heart Circ Physiol. 2011 Oct; 301(4):H1255-65. PMID: 21724864.
    Citations: 35     Fields:    Translation:AnimalsCells
  35. Zakharov MN, Pillai BK, Bhasin S, Ulloor J, Istomin AY, Guo C, Godzik A, Kumar R, Jasuja R. Dynamics of coregulator-induced conformational perturbations in androgen receptor ligand binding domain. Mol Cell Endocrinol. 2011 Jul 20; 341(1-2):1-8. PMID: 21605623.
    Citations: 2     Fields:    Translation:AnimalsCells
  36. Jayaraman S, Jasuja R, Zakharov MN, Gursky O. Pressure perturbation calorimetry of lipoproteins reveals an endothermic transition without detectable volume changes. Implications for adsorption of apolipoprotein to a phospholipid surface. Biochemistry. 2011 May 17; 50(19):3919-27. PMID: 21452855.
    Citations: 5     Fields:    Translation:HumansCells
  37. Serra C, Bhasin S, Tangherlini F, Barton ER, Ganno M, Zhang A, Shansky J, Vandenburgh HH, Travison TG, Jasuja R, Morris C. The role of GH and IGF-I in mediating anabolic effects of testosterone on androgen-responsive muscle. Endocrinology. 2011 Jan; 152(1):193-206. PMID: 21084444.
    Citations: 33     Fields:    Translation:HumansAnimalsCells
  38. Pillai BK, Jasuja R, Simard JR, Hamilton JA. Fast diffusion of very long chain saturated fatty acids across a bilayer membrane and their rapid extraction by cyclodextrins: implications for adrenoleukodystrophy. J Biol Chem. 2009 Nov 27; 284(48):33296-304. PMID: 19801636.
    Citations: 8     Fields:    Translation:HumansCells
  39. Guo W, Wong S, Pudney J, Jasuja R, Hua N, Jiang L, Miller A, Hruz PW, Hamilton JA, Bhasin S. Acipimox, an inhibitor of lipolysis, attenuates atherogenesis in LDLR-null mice treated with HIV protease inhibitor ritonavir. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):2028-32. PMID: 19762785.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  40. Jasuja R, Ulloor J, Yengo CM, Choong K, Istomin AY, Livesay DR, Jacobs DJ, Swerdloff RS, Miksovská J, Larsen RW, Bhasin S. Kinetic and thermodynamic characterization of dihydrotestosterone-induced conformational perturbations in androgen receptor ligand-binding domain. Mol Endocrinol. 2009 Aug; 23(8):1231-41. PMID: 19443608.
    Citations: 9     Fields:    Translation:HumansCells
  41. Bhasin S, Jasuja R. Selective androgen receptor modulators as function promoting therapies. Curr Opin Clin Nutr Metab Care. 2009 May; 12(3):232-40. PMID: 19357508.
    Citations: 35     Fields:    Translation:HumansAnimals
  42. Singh R, Bhasin S, Braga M, Artaza JN, Pervin S, Taylor WE, Krishnan V, Sinha SK, Rajavashisth TB, Jasuja R. Regulation of myogenic differentiation by androgens: cross talk between androgen receptor/ beta-catenin and follistatin/transforming growth factor-beta signaling pathways. Endocrinology. 2009 Mar; 150(3):1259-68. PMID: 18948405.
    Citations: 53     Fields:    Translation:AnimalsCells
  43. Gupta V, Bhasin S, Guo W, Singh R, Miki R, Chauhan P, Choong K, Tchkonia T, Lebrasseur NK, Flanagan JN, Hamilton JA, Viereck JC, Narula NS, Kirkland JL, Jasuja R. Effects of dihydrotestosterone on differentiation and proliferation of human mesenchymal stem cells and preadipocytes. Mol Cell Endocrinol. 2008 Dec 16; 296(1-2):32-40. PMID: 18801408.
    Citations: 52     Fields:    Translation:HumansAnimalsCells
  44. Bhasin S, Zhang A, Coviello A, Jasuja R, Ulloor J, Singh R, Vesper H, Vasan RS. The impact of assay quality and reference ranges on clinical decision making in the diagnosis of androgen disorders. Steroids. 2008 Dec 12; 73(13):1311-7. PMID: 18687348.
    Citations: 25     Fields:    Translation:Humans
  45. Guo W, Flanagan J, Jasuja R, Kirkland J, Jiang L, Bhasin S. The effects of myostatin on adipogenic differentiation of human bone marrow-derived mesenchymal stem cells are mediated through cross-communication between Smad3 and Wnt/beta-catenin signaling pathways. J Biol Chem. 2008 Apr 04; 283(14):9136-45. PMID: 18203713.
    Citations: 45     Fields:    Translation:HumansCells
  46. Montano M, Flanagan JN, Jiang L, Sebastiani P, Rarick M, LeBrasseur NK, Morris CA, Jasuja R, Bhasin S. Transcriptional profiling of testosterone-regulated genes in the skeletal muscle of human immunodeficiency virus-infected men experiencing weight loss. J Clin Endocrinol Metab. 2007 Jul; 92(7):2793-802. PMID: 17440010.
    Citations: 8     Fields:    Translation:HumansCells
  47. Bhasin S, Calof OM, Storer TW, Lee ML, Mazer NA, Jasuja R, Montori VM, Gao W, Dalton JT. Drug insight: Testosterone and selective androgen receptor modulators as anabolic therapies for chronic illness and aging. Nat Clin Pract Endocrinol Metab. 2006 Mar; 2(3):146-59. PMID: 16932274.
    Citations: 87     Fields:    Translation:Humans
  48. Jasuja R, Ramaraj P, Mac RP, Singh AB, Storer TW, Artaza J, Miller A, Singh R, Taylor WE, Lee ML, Davidson T, Sinha-Hikim I, Gonzalez-Cadavid N, Bhasin S. Delta-4-androstene-3,17-dione binds androgen receptor, promotes myogenesis in vitro, and increases serum testosterone levels, fat-free mass, and muscle strength in hypogonadal men. J Clin Endocrinol Metab. 2005 Feb; 90(2):855-63. PMID: 15522925.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  49. Bhasin S, Taylor WE, Singh R, Artaza J, Sinha-Hikim I, Jasuja R, Choi H, Gonzalez-Cadavid NF. The mechanisms of androgen effects on body composition: mesenchymal pluripotent cell as the target of androgen action. J Gerontol A Biol Sci Med Sci. 2003 Dec; 58(12):M1103-10. PMID: 14684707.
    Citations: 52     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.