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Lidia Minguez Alarcon, Ph.D.

Other Positions

University of Murcia School of MedicinePhD
University of Murcia School of MedicineMPH
University of Valencia School of PharmacyBPharm

With joint appointments both at the Harvard Medical School/Brigham and Women s Hospital as well as the Harvard TH Chan School of Public Health, Dr. Minguez-Alarcon s research focuses on identifying chemical and non-chemical stressors of human fertility, reproductive and cardiometabolic health. She is also evaluating fertility measures as predictors of long-term health. As an environmental and reproductive epidemiologist, she is primarily working in the EARTH Study, a prospective cohort study of subfertile couples at the MGH fertility center in Boston. She is also an active collaborator in the Russian Children s Study, PEACE Study, Project Viva, NHS2, NHS3 and VDAART. Dr. Mínguez-Alarcón is the PI of the recently NIH funded Longitudinal Investigation of Health and Diseases after Infertility (LIHDI) Study, which will re-enroll former female EARTH participants to assess their health at midlife. She will prospectively explore chemical exposures during reproductive years in relation to long-term cardiovascular and metabolic health and whether fertility measures mediate the associations. She brings her expertise to the Science of the Total Environment (STOTEN) journal as an Associate Editor.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01ES033651 (MINGUEZ ALARCON, LIDIA) Jul 5, 2022 - Apr 30, 2027
    Exposure to phthalates and OP flame retardants and long-term maternal cardiovascular and metabolic health
    Role: Principal Investigator
  2. U54AG062322 (JOFFE, HADINE) Jun 1, 2020 - May 31, 2025
    Center for Stress and Neural Regulation of Reproductive Aging Health Outcomes
    Role: Collaborator
  3. R24ES028521 (LADEN, FRANCINE) Sep 30, 2018 - Jun 30, 2023
    Nurses Health Study 3: A multiple exposure environmental epidemiology cohort of young adults
    Role: Collaborator
  4. R01HD093761 (CHAVARRO, JORGE EDUARDO) Sep 1, 2018 - Jun 30, 2023
    Long-term health consequences of birth by cesarean section
    Role: Collaborator
  5. R01ES028298 (PILSNER, J. RICHARD) Aug 15, 2018 - May 31, 2023
    Paternal preconception phthalates and reproductive health - potential mediation through sperm DNA methylation.
    Role: Co-Investigator

Featured Content

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Mínguez-Alarcón L, Bellavia A, Gaskins AJ, Chavarro JE, Ford JB, Souter I, Calafat AM, Hauser R, Williams PL. Paternal mixtures of urinary concentrations of phthalate metabolites, bisphenol A and parabens in relation to pregnancy outcomes among couples attending a fertility center. Environ Int. 2021 01; 146:106171. PMID: 33069985.
    Citations: 4     Fields:    Translation:Humans
  2. Li MC, Mínguez-Alarcón L, Bellavia A, Williams PL, James-Todd T, Hauser R, Chavarro JE, Chiu YH. Serum beta-carotene modifies the association between phthalate mixtures and insulin resistance: The National Health and Nutrition Examination Survey 2003-2006. Environ Res. 2019 11; 178:108729. PMID: 31521963.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  3. Gaskins AJ, Mínguez-Alarcón L, Fong KC, Abu Awad Y, Di Q, Chavarro JE, Ford JB, Coull BA, Schwartz J, Kloog I, Attaman J, Hauser R, Laden F. Supplemental Folate and the Relationship Between Traffic-Related Air Pollution and Livebirth Among Women Undergoing Assisted Reproduction. Am J Epidemiol. 2019 09 01; 188(9):1595-1604. PMID: 31241127; PMCID: PMC6736414.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  4. Bellavia A, Mínguez-Alarcón L, Ford JB, Keller M, Petrozza J, Williams PL, Hauser R, James-Todd T. Association of self-reported personal care product use with blood glucose levels measured during pregnancy among women from a fertility clinic. Sci Total Environ. 2019 Dec 10; 695:133855. PMID: 31421341.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  5. Ghayda RA, Williams PL, Chavarro JE, Ford JB, Souter I, Calafat AM, Hauser R, Mínguez-Alarcón L. Urinary bisphenol S concentrations: Potential predictors of and associations with semen quality parameters among men attending a fertility center. Environ Int. 2019 10; 131:105050. PMID: 31376593.
    Citations: 12     Fields:    Translation:Humans
  6. Martín-Calvo N, Mínguez-Alarcón L, Gaskins AJ, Nassan FL, Williams PL, Souter I, Hauser R, Chavarro JE. Paternal preconception folate intake in relation to gestational age at delivery and birthweight of newborns conceived through assisted reproduction. Reprod Biomed Online. 2019 Nov; 39(5):835-843. PMID: 31564651.
    Citations: 4     Fields:    Translation:Humans
  7. Gaskins AJ, Mínguez-Alarcón L, Fong KC, Abdelmessih S, Coull BA, Chavarro JE, Schwartz J, Kloog I, Souter I, Hauser R, Laden F. Exposure to Fine Particulate Matter and Ovarian Reserve Among Women from a Fertility Clinic. Epidemiology. 2019 07; 30(4):486-491. PMID: 31162281.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  8. Yland J, Messerlian C, Mínguez-Alarcón L, Ford JB, Hauser R, Williams PL. Methodological approaches to analyzing IVF data with multiple cycles. Hum Reprod. 2019 03 01; 34(3):549-557. PMID: 30576499; PMCID: PMC6389861.
    Citations: 15     Fields:    Translation:Humans
  9. Mínguez-Alarcón L, Messerlian C, Bellavia A, Gaskins AJ, Chiu YH, Ford JB, Azevedo AR, Petrozza JC, Calafat AM, Hauser R, Williams PL. Urinary concentrations of bisphenol A, parabens and phthalate metabolite mixtures in relation to reproductive success among women undergoing in vitro fertilization. Environ Int. 2019 05; 126:355-362. PMID: 30826614; PMCID: PMC6469504.
    Citations: 26     Fields:    Translation:Humans
  10. Li MC, Mínguez-Alarcón L, Arvizu M, Chiu YH, Ford JB, Williams PL, Attaman J, Hauser R, Chavarro JE. Waist circumference in relation to outcomes of infertility treatment with assisted reproductive technologies. Am J Obstet Gynecol. 2019 06; 220(6):578.e1-578.e13. PMID: 30763543; PMCID: PMC6545132.
    Citations: 4     Fields:    Translation:Humans
  11. Mínguez-Alarcón L, Williams PL, Chiu YH, Gaskins AJ, Nassan FL, Dadd R, Petrozza J, Hauser R, Chavarro JE. Secular trends in semen parameters among men attending a fertility center between 2000 and 2017: Identifying potential predictors. Environ Int. 2018 12; 121(Pt 2):1297-1303. PMID: 30389382.
    Citations: 30     Fields:    Translation:HumansCells
  12. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, Messerlian C, Williams PL, Ford JB, Souter I, Hauser R, Chavarro JE. Type of underwear worn and markers of testicular function among men attending a fertility center. Hum Reprod. 2018 09 01; 33(9):1749-1756. PMID: 30102388; PMCID: PMC6530653.
    Citations: 12     Fields:    Translation:Humans
  13. Korevaar TIM, Mínguez-Alarcón L, Messerlian C, de Poortere RA, Williams PL, Broeren MA, Hauser R, Souter IC. Association of Thyroid Function and Autoimmunity with Ovarian Reserve in Women Seeking Infertility Care. Thyroid. 2018 10; 28(10):1349-1358. PMID: 29943679.
    Citations: 18     Fields:    Translation:Humans
  14. Ingle ME, Mínguez-Alarcón L, Carignan CC, Butt CM, Stapleton HM, Williams PL, Ford JB, Hauser R, Meeker JD. The association between urinary concentrations of phosphorous-containing flame retardant metabolites and semen parameters among men from a fertility clinic. Int J Hyg Environ Health. 2018 06; 221(5):809-815. PMID: 29739653; PMCID: PMC5997557.
    Citations: 8     Fields:    Translation:HumansPHPublic Health
  15. Chiu YH, Williams PL, Gillman MW, Gaskins AJ, Mínguez-Alarcón L, Souter I, Toth TL, Ford JB, Hauser R, Chavarro JE. Association Between Pesticide Residue Intake From Consumption of Fruits and Vegetables and Pregnancy Outcomes Among Women Undergoing Infertility Treatment With Assisted Reproductive Technology. JAMA Intern Med. 2018 01 01; 178(1):17-26. PMID: 29084307; PMCID: PMC5814112.
    Citations: 30     Fields:    Translation:HumansAnimalsPHPublic Health
  16. Carignan CC, Mínguez-Alarcón L, Williams PL, Meeker JD, Stapleton HM, Butt CM, Toth TL, Ford JB, Hauser R. Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization. Environ Int. 2018 02; 111:232-238. PMID: 29241080.
    Citations: 21     Fields:    Translation:HumansPHPublic Health
  17. Mínguez-Alarcón L, Afeiche MC, Williams PL, Arvizu M, Tanrikut C, Amarasiriwardena CJ, Ford JB, Hauser R, Chavarro JE. Hair mercury (Hg) levels, fish consumption and semen parameters among men attending a fertility center. Int J Hyg Environ Health. 2018 03; 221(2):174-182. PMID: 29102416.
    Citations: 10     Fields:    Translation:HumansAnimalsPHPublic Health
  18. Chiu YH, Williams PL, Mínguez-Alarcón L, Gillman M, Sun Q, Ospina M, Calafat AM, Hauser R, Chavarro JE. Comparison of questionnaire-based estimation of pesticide residue intake from fruits and vegetables with urinary concentrations of pesticide biomarkers. J Expo Sci Environ Epidemiol. 2018 01; 28(1):31-39. PMID: 28930298.
    Citations: 18     Fields:    Translation:HumansAnimalsPHPublic Health
  19. Carignan CC, Mínguez-Alarcón L, Butt CM, Williams PL, Meeker JD, Stapleton HM, Toth TL, Ford JB, Hauser R. Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization. Environ Health Perspect. 2017 08 25; 125(8):087018. PMID: 28858831; PMCID: PMC5783651.
    Citations: 41     Fields:    Translation:Humans
  20. Mínguez-Alarcón L, Christou G, Messerlian C, Williams PL, Carignan CC, Souter I, Ford JB, Calafat AM, Hauser R. Urinary triclosan concentrations and diminished ovarian reserve among women undergoing treatment in a fertility clinic. Fertil Steril. 2017 08; 108(2):312-319. PMID: 28583664; PMCID: PMC5545065.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  21. MInguez-Alarcón L, Chavarro JE, Mendiola J, Roca M, Tanrikut C, Vioque J, Jørgensen N, Torres-Cantero AM. Fatty acid intake in relation to reproductive hormones and testicular volume among young healthy men. Asian J Androl. 2017 Mar-Apr; 19(2):184-190. PMID: 27834316; PMCID: PMC5312216.
    Citations: 17     Fields:    Translation:Humans
  22. Mínguez-Alarcón L, Souter I, Williams PL, Ford JB, Hauser R, Chavarro JE, Gaskins AJ. Occupational factors and markers of ovarian reserve and response among women at a fertility centre. Occup Environ Med. 2017 06; 74(6):426-431. PMID: 28167499.
    Citations: 12     Fields:    Translation:HumansPHPublic Health
  23. Mínguez-Alarcón L, Sergeyev O, Burns JS, Williams PL, Lee MM, Korrick SA, Smigulina L, Revich B, Hauser R. A Longitudinal Study of Peripubertal Serum Organochlorine Concentrations and Semen Parameters in Young Men: The Russian Children's Study. Environ Health Perspect. 2017 03; 125(3):460-466. PMID: 27713107; PMCID: PMC5332179.
    Citations: 23     Fields:    Translation:HumansPHPublic Health
  24. Mínguez-Alarcón L, Souter I, Chiu YH, Williams PL, Ford JB, Ye X, Calafat AM, Hauser R. Urinary concentrations of cyclohexane-1,2-dicarboxylic acid monohydroxy isononyl ester, a metabolite of the non-phthalate plasticizer di(isononyl)cyclohexane-1,2-dicarboxylate (DINCH), and markers of ovarian response among women attending a fertility center. Environ Res. 2016 Nov; 151:595-600. PMID: 27591839; PMCID: PMC5071161.
    Citations: 11     Fields:    Translation:HumansCells
  25. Mínguez-Alarcón L, Gaskins AJ, Chiu YH, Souter I, Williams PL, Calafat AM, Hauser R, Chavarro JE. Dietary folate intake and modification of the association of urinary bisphenol A concentrations with in vitro fertilization outcomes among women from a fertility clinic. Reprod Toxicol. 2016 10; 65:104-112. PMID: 27423903; PMCID: PMC5067190.
    Citations: 19     Fields:    Translation:Humans
  26. Mínguez-Alarcón L, Mendiola J, López-Espín JJ, Sarabia-Cos L, Vivero-Salmerón G, Vioque J, Navarrete-Muñoz EM, Torres-Cantero AM. Dietary intake of antioxidant nutrients is associated with semen quality in young university students. Hum Reprod. 2012 Sep; 27(9):2807-14. PMID: 22752607.
    Citations: 25     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.