Harvard Catalyst Profiles

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Shadi Salloum, Ph.D., M.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Altinbas A, Holmes JA, Salloum S, Lidofsky A, Alatrakchi N, Somsouk M, Hunt P, Deeks S, Chew KW, Lauer G, Kruger A, Lin W, Chung RT. LOXL-2 and TNC-C are markers of liver fibrogenesis in HCV/HIV-, HIV- and HCV-infected patients. Biomark Med. 2022 08; 16(11):839-846. PMID: 35786977; PMCID: PMC9437769.
    Citations:    Fields:    Translation:Humans
  2. Kim MH, Kim MY, Salloum S, Qian T, Wong LP, Xu M, Lee Y, Shroff SG, Sadreyev RI, Corey KE, Baumert TF, Hoshida Y, Chung RT. Atorvastatin favorably modulates a clinical hepatocellular carcinoma risk gene signature. Hepatol Commun. 2022 09; 6(9):2581-2593. PMID: 35712812; PMCID: PMC9426409.
    Citations:    Fields:    
  3. Sojoodi M, Erstad DJ, Barrett SC, Salloum S, Zhu S, Qian T, Colon S, Gale EM, Jordan VC, Wang Y, Li S, Ataeinia B, Jalilifiroozinezhad S, Lanuti M, Zukerberg L, Caravan P, Hoshida Y, Chung RT, Bhave G, Lauer GM, Fuchs BC, Tanabe KK. Peroxidasin Deficiency Re-programs Macrophages Toward Pro-fibrolysis Function and Promotes Collagen Resolution in Liver. Cell Mol Gastroenterol Hepatol. 2022; 13(5):1483-1509. PMID: 35093588; PMCID: PMC9043497.
    Citations:    Fields:    Translation:HumansAnimalsCells
  4. Li W, Duan X, Zhu C, Liu X, Jeyarajan AJ, Xu M, Tu Z, Sheng Q, Chen D, Zhu C, Shao T, Cheng Z, Salloum S, Schaefer EA, Kruger AJ, Holmes JA, Chung RT, Lin W. Hepatitis B and Hepatitis C Virus Infection Promote Liver Fibrogenesis through a TGF-ß1-Induced OCT4/Nanog Pathway. J Immunol. 2022 02 01; 208(3):672-684. PMID: 35022275; PMCID: PMC8770612.
    Citations:    Fields:    Translation:HumansCells
  5. Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z, Gao C, Li JZ, Sadreyev RI, Yu XG, Chung RT. Type I, II, and III Interferon Signatures Correspond to Coronavirus Disease 2019 Severity. J Infect Dis. 2021 09 01; 224(5):777-782. PMID: 34467988; PMCID: PMC8244575.
    Citations: 11     Fields:    Translation:HumansCells
  6. Salloum S, Jeyarajan AJ, Kruger AJ, Holmes JA, Shao T, Sojoodi M, Kim MH, Zhuo Z, Shroff SG, Kassa A, Corey KE, Khan SK, Lin W, Alatrakchi N, Schaefer EAK, Chung RT. Fatty Acids Activate the Transcriptional Coactivator YAP1 to Promote Liver Fibrosis via p38 Mitogen-Activated Protein Kinase. Cell Mol Gastroenterol Hepatol. 2021; 12(4):1297-1310. PMID: 34118488; PMCID: PMC8463869.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  7. Kim MH, Salloum S, Wang JY, Lai Ping W, Regan J, Lefteri K, Manickas-Hill Z, Gao C, Li JZ, Sadreyev RI, Yu XG, Chung RT. Type I, II, and III interferon signatures correspond to COVID-19 disease severity. J Infect Dis. 2021 May 24. PMID: 34036353.
    Citations: 1     Fields:    
  8. Kim MH, Salloum S, Wang JY, Wong LP, Regan J, Lefteri K, Manickas-Hill Z, Li JZ, Sadreyev RI, Yu XG, Chung RT. Type I, II, and III interferon signatures correspond to COVID-19 disease severity. medRxiv. 2021 Mar 12. PMID: 33758894; PMCID: PMC7987053.
  9. Liu X, Duan X, Holmes JA, Li W, Lee SH, Tu Z, Zhu C, Salloum S, Lidofsky A, Schaefer EA, Cai D, Li S, Wang H, Huang Y, Zhao Y, Yu ML, Xu Z, Chen L, Hong J, Lin W, Chung RT. A Long Noncoding RNA Regulates Hepatitis C Virus Infection Through Interferon Alpha-Inducible Protein 6. Hepatology. 2019 03; 69(3):1004-1019. PMID: 30199576.
    Citations: 24     Fields:    Translation:HumansCells
  10. Lidofsky A, Holmes JA, Feeney ER, Kruger AJ, Salloum S, Zheng H, Seguin IS, Altinbas A, Masia R, Corey KE, Gustafson JL, Schaefer EA, Hunt PW, Deeks S, Somsouk M, Chew KW, Chung RT, Alatrakchi N. Macrophage Activation Marker Soluble CD163 Is a Dynamic Marker of Liver Fibrogenesis in Human Immunodeficiency Virus/Hepatitis C Virus Coinfection. J Infect Dis. 2018 09 22; 218(9):1394-1403. PMID: 29868909; PMCID: PMC6151081.
    Citations: 21     Fields:    Translation:HumansCells
  11. Duan X, Li S, Holmes JA, Tu Z, Li Y, Cai D, Liu X, Li W, Yang C, Jiao B, Schaefer EA, Fusco DN, Salloum S, Chen L, Lin W, Chung RT. MicroRNA 130a Regulates both Hepatitis C Virus and Hepatitis B Virus Replication through a Central Metabolic Pathway. J Virol. 2018 04 01; 92(7). PMID: 29321333; PMCID: PMC5972888.
    Citations: 11     Fields:    Translation:HumansCells
  12. Kruger AJ, Fuchs BC, Masia R, Holmes JA, Salloum S, Sojoodi M, Ferreira DS, Rutledge SM, Caravan P, Alatrakchi N, Vig P, Lefebvre E, Chung RT. Prolonged cenicriviroc therapy reduces hepatic fibrosis despite steatohepatitis in a diet-induced mouse model of nonalcoholic steatohepatitis. Hepatol Commun. 2018 May; 2(5):529-545. PMID: 29761169; PMCID: PMC5944590.
    Citations: 22     Fields:    
  13. Schaefer E, Wu W, Mark C, Yang A, DiGiacomo E, Carlton-Smith C, Salloum S, Brisac C, Lin W, Corey KE, Chung RT. Intermittent hypoxia is a proinflammatory stimulus resulting in IL-6 expression and M1 macrophage polarization. Hepatol Commun. 2017 06; 1(4):326-337. PMID: 29404462; PMCID: PMC5721395.
    Citations: 10     Fields:    
  14. Schaefer EA, Meixiong J, Mark C, Deik A, Motola DL, Fusco D, Yang A, Brisac C, Salloum S, Lin W, Clish CB, Peng LF, Chung RT. Apolipoprotein B100 is required for hepatitis C infectivity and Mipomersen inhibits hepatitis C. World J Gastroenterol. 2016 Dec 07; 22(45):9954-9965. PMID: 28018102; PMCID: PMC5143762.
    Citations: 4     Fields:    Translation:HumansCells
  15. Salloum S, Holmes JA, Jindal R, Bale SS, Brisac C, Alatrakchi N, Lidofsky A, Kruger AJ, Fusco DN, Luther J, Schaefer EA, Lin W, Yarmush ML, Chung RT. Exposure to human immunodeficiency virus/hepatitis C virus in hepatic and stellate cell lines reveals cooperative profibrotic transcriptional activation between viruses and cell types. Hepatology. 2016 12; 64(6):1951-1968. PMID: 27531241.
    Citations: 21     Fields:    Translation:HumansCells
  16. Brisac C, Salloum S, Yang V, Schaefer EA, Holmes JA, Chevaliez S, Hong J, Carlton-Smith C, Alatrakchi N, Kruger A, Lin W, Chung RT. IQGAP2 is a novel interferon-alpha antiviral effector gene acting non-conventionally through the NF-?B pathway. J Hepatol. 2016 11; 65(5):972-979. PMID: 27401546; PMCID: PMC5656012.
    Citations: 8     Fields:    Translation:HumansCells
  17. Salloum S, Wang H, Ferguson C, Parton RG, Tai AW. Rab18 binds to hepatitis C virus NS5A and promotes interaction between sites of viral replication and lipid droplets. PLoS Pathog. 2013; 9(8):e1003513. PMID: 23935497.
    Citations: 70     Fields:    Translation:HumansCells
  18. Salloum S, Tai AW. Treating hepatitis C infection by targeting the host. Transl Res. 2012 Jun; 159(6):421-9. PMID: 22633094; PMCID: PMC3361678.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  19. Tai AW, Salloum S. The role of the phosphatidylinositol 4-kinase PI4KA in hepatitis C virus-induced host membrane rearrangement. PLoS One. 2011; 6(10):e26300. PMID: 22022594.
    Citations: 49     Fields:    Translation:HumansCells
  20. Salloum S, Kluge SF, Kim AY, Roggendorf M, Timm J. The resistance mutation R155K in the NS3/4A protease of hepatitis C virus also leads the virus to escape from HLA-A*68-restricted CD8 T cells. Antiviral Res. 2010 Aug; 87(2):272-5. PMID: 20488208.
    Citations: 5     Fields:    Translation:HumansCells
  21. Ross RS, Viazov S, Salloum S, Hilgard P, Gerken G, Roggendorf M. Analytical performance characteristics and clinical utility of a novel assay for total hepatitis C virus core antigen quantification. J Clin Microbiol. 2010 Apr; 48(4):1161-8. PMID: 20107102.
    Citations: 27     Fields:    Translation:HumansCells
  22. Salloum S, Oniangue-Ndza C, Neumann-Haefelin C, Hudson L, Giugliano S, aus dem Siepen M, Nattermann J, Spengler U, Lauer GM, Wiese M, Klenerman P, Bright H, Scherbaum N, Thimme R, Roggendorf M, Viazov S, Timm J. Escape from HLA-B*08-restricted CD8 T cells by hepatitis C virus is associated with fitness costs. J Virol. 2008 Dec; 82(23):11803-12. PMID: 18815309; PMCID: PMC2583685.
    Citations: 25     Fields:    Translation:HumansCells
  23. Neumann-Haefelin C, Frick DN, Wang JJ, Pybus OG, Salloum S, Narula GS, Eckart A, Biezynski A, Eiermann T, Klenerman P, Viazov S, Roggendorf M, Thimme R, Reiser M, Timm J. Analysis of the evolutionary forces in an immunodominant CD8 epitope in hepatitis C virus at a population level. J Virol. 2008 Apr; 82(7):3438-51. PMID: 18216107.
    Citations: 32     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.