Harvard Catalyst Profiles

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Nikolaus Jilg, M.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Gaebler C, Nogueira L, Stoffel E, Oliveira TY, Breton G, Millard KG, Turroja M, Butler A, Ramos V, Seaman MS, Reeves JD, Petroupoulos CJ, Shimeliovich I, Gazumyan A, Jiang CS, Jilg N, Scheid JF, Gandhi R, Walker BD, Sneller MC, Fauci A, Chun TW, Caskey M, Nussenzweig MC. Prolonged viral suppression with anti-HIV-1 antibody therapy. Nature. 2022 06; 606(7913):368-374. PMID: 35418681; PMCID: PMC9177424.
    Citations:    Fields:    Translation:HumansCells
  2. Francis JM, Leistritz-Edwards D, Dunn A, Tarr C, Lehman J, Dempsey C, Hamel A, Rayon V, Liu G, Wang Y, Wille M, Durkin M, Hadley K, Sheena A, Roscoe B, Ng M, Rockwell G, Manto M, Gienger E, Nickerson J, Moarefi A, Noble M, Malia T, Bardwell PD, Gordon W, Swain J, Skoberne M, Sauer K, Harris T, Goldrath AW, Shalek AK, Coyle AJ, Benoist C, Pregibon DC. Allelic variation in class I HLA determines CD8+ T cell repertoire shape and cross-reactive memory responses to SARS-CoV-2. Sci Immunol. 2022 01 21; 7(67):eabk3070. PMID: 34793243; PMCID: PMC9017864.
    Citations: 10     Fields:    Translation:HumansCells
  3. Mohareb AM, Rosenberg JM, Bhattacharyya RP, Kotton CN, Chu JT, Jilg N, Hysell KM, Albin JS, Sen P, Bloom SM, Schiff AE, Zachary KC, Letourneau AR, Kim AY, Hurtado RM. Preventing Infectious Complications of Immunomodulation in COVID-19 in Foreign-Born Patients. J Immigr Minor Health. 2021 Dec; 23(6):1343-1347. PMID: 34159495; PMCID: PMC8218971.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  4. Jilg N, Lau ES, Baker MA, Levy BD, Loscalzo J. A Treacherous Course. N Engl J Med. 2021 Mar 04; 384(9):860-865. PMID: 33657298.
    Citations:    Fields:    Translation:Humans
  5. Little J, Vaidya A, Jilg N, Lau E, Baker M. A Treacherous Course. N Engl J Med. 2021 Feb 04; 384(5):e10. PMID: 33534978.
    Citations:    Fields:    Translation:Humans
  6. Jilg N, Garcia-Broncano P, Peluso M, Segal FP, Bosch RJ, Roberts-Toler C, Chen SMY, Van Dam CN, Keefer MC, Kuritzkes DR, Landay AL, Deeks S, Yu XG, Sax PE, Li JZ. Maintenance of Viral Suppression in Human Immunodeficiency Virus Controllers Despite Waning T-Cell Responses During Antiretroviral Therapy. J Infect Dis. 2020 11 09; 222(11):1837-1842. PMID: 32496516; PMCID: PMC7896274.
    Citations: 1     Fields:    Translation:HumansCells
  7. Fajnzylber J, Regan J, Coxen K, Corry H, Wong C, Rosenthal A, Worrall D, Giguel F, Piechocka-Trocha A, Atyeo C, Fischinger S, Chan A, Flaherty KT, Hall K, Dougan M, Ryan ET, Gillespie E, Chishti R, Li Y, Jilg N, Hanidziar D, Baron RM, Baden L, Tsibris AM, Armstrong KA, Kuritzkes DR, Alter G, Walker BD, Yu X, Li JZ. SARS-CoV-2 viral load is associated with increased disease severity and mortality. Nat Commun. 2020 10 30; 11(1):5493. PMID: 33127906.
    Citations: 262     Fields:    Translation:HumansCellsPHPublic Health
  8. Stone GS, Glover M, Jilg N, Sfeir MM. Case 40-2019: A 26-Year-Old Returning Traveler with Headache. N Engl J Med. 2019 Dec 26; 381(26):2553-2560. PMID: 31881142.
    Citations: 1     Fields:    Translation:HumansCells
  9. Jilg N, Li JZ. On the Road to a HIV Cure: Moving Beyond Berlin and London. Infect Dis Clin North Am. 2019 09; 33(3):857-868. PMID: 31395147.
    Citations: 8     Fields:    Translation:HumansCells
  10. Geisler BP, Jilg N, Patton RG, Pietzsch JB. Model to evaluate the impact of hospital-based interventions targeting false-positive blood cultures on economic and clinical outcomes. J Hosp Infect. 2019 Aug; 102(4):438-444. PMID: 30928573.
    Citations: 5     Fields:    Translation:Humans
  11. Jilg N, Hunt PW, Gandhi RT. HIV DNA decay during antiretroviral therapy: lessons from a clinic-based cohort study. AIDS. 2018 09 24; 32(15):2255-2257. PMID: 30212405; PMCID: PMC6505463.
    Citations: 1     Fields:    Translation:HumansCells
  12. Chusri P, Kumthip K, Hong J, Zhu C, Duan X, Jilg N, Fusco DN, Brisac C, Schaefer EA, Cai D, Peng LF, Maneekarn N, Lin W, Chung RT. HCV induces transforming growth factor ß1 through activation of endoplasmic reticulum stress and the unfolded protein response. Sci Rep. 2016 Mar 01; 6:22487. PMID: 26927933; PMCID: PMC4772380.
    Citations: 40     Fields:    Translation:HumansCells
  13. Lin W, Zhu C, Hong J, Zhao L, Jilg N, Fusco DN, Schaefer EA, Brisac C, Liu X, Peng LF, Xu Q, Chung RT. The spliceosome factor SART1 exerts its anti-HCV action through mRNA splicing. J Hepatol. 2015 May; 62(5):1024-32. PMID: 25481564; PMCID: PMC4404186.
    Citations: 19     Fields:    Translation:HumansCells
  14. Jilg N, Lin W, Hong J, Schaefer EA, Wolski D, Meixong J, Goto K, Brisac C, Chusri P, Fusco DN, Chevaliez S, Luther J, Kumthip K, Urban TJ, Peng LF, Lauer GM, Chung RT. Kinetic differences in the induction of interferon stimulated genes by interferon-a and interleukin 28B are altered by infection with hepatitis C virus. Hepatology. 2014 Apr; 59(4):1250-61. PMID: 23913866.
    Citations: 58     Fields:    Translation:HumansCells
  15. Fofana I, Jilg N, Chung RT, Baumert TF. Entry inhibitors and future treatment of hepatitis C. Antiviral Res. 2014 Apr; 104:136-42. PMID: 24525381.
    Citations: 10     Fields:    Translation:HumansAnimalsCells
  16. Goto K, Lin W, Zhang L, Jilg N, Shao RX, Schaefer EA, Zhao H, Fusco DN, Peng LF, Kato N, Chung RT. The AMPK-related kinase SNARK regulates hepatitis C virus replication and pathogenesis through enhancement of TGF-ß signaling. J Hepatol. 2013 Nov; 59(5):942-8. PMID: 23831117; PMCID: PMC3866804.
    Citations: 15     Fields:    Translation:HumansCells
  17. Jilg N, Chung RT. One more piece in the interleukin 28B gene puzzle? The case of hepatitis B. Hepatology. 2013 Mar; 57(3):870-2. PMID: 22911469.
    Citations: 6     Fields:    Translation:HumansCells
  18. Fusco DN, Brisac C, John SP, Huang YW, Chin CR, Xie T, Zhao H, Jilg N, Zhang L, Chevaliez S, Wambua D, Lin W, Peng L, Chung RT, Brass AL. A genetic screen identifies interferon-a effector genes required to suppress hepatitis C virus replication. Gastroenterology. 2013 Jun; 144(7):1438-49, 1449.e1-9. PMID: 23462180; PMCID: PMC3665646.
    Citations: 24     Fields:    Translation:HumansCells
  19. Shao RX, Zhang L, Hong Z, Goto K, Cheng D, Chen WC, Jilg N, Kumthip K, Fusco DN, Peng LF, Chung RT. SOCS1 abrogates IFN's antiviral effect on hepatitis C virus replication. Antiviral Res. 2013 Feb; 97(2):101-7. PMID: 23237992.
    Citations: 12     Fields:    Translation:HumansCells
  20. Kumthip K, Chusri P, Jilg N, Zhao L, Fusco DN, Zhao H, Goto K, Cheng D, Schaefer EA, Zhang L, Pantip C, Thongsawat S, O'Brien A, Peng LF, Maneekarn N, Chung RT, Lin W. Hepatitis C virus NS5A disrupts STAT1 phosphorylation and suppresses type I interferon signaling. J Virol. 2012 Aug; 86(16):8581-91. PMID: 22674974.
    Citations: 41     Fields:    Translation:HumansCells
  21. Zhao H, Lin W, Kumthip K, Cheng D, Fusco DN, Hofmann O, Jilg N, Tai AW, Goto K, Zhang L, Hide W, Jang JY, Peng LF, Chung RT. A functional genomic screen reveals novel host genes that mediate interferon-alpha's effects against hepatitis C virus. J Hepatol. 2012 Feb; 56(2):326-33. PMID: 21888876.
    Citations: 39     Fields:    Translation:HumansCells
  22. Jilg N, Chung RT. Adding to the toolbox: receptor tyrosine kinases as potential targets in the treatment of hepatitis C. J Hepatol. 2012 Jan; 56(1):282-4. PMID: 21784050.
    Citations: 3     Fields:    
  23. Zhang L, Jilg N, Shao RX, Lin W, Fusco DN, Zhao H, Goto K, Peng LF, Chen WC, Chung RT. IL28B inhibits hepatitis C virus replication through the JAK-STAT pathway. J Hepatol. 2011 Aug; 55(2):289-98. PMID: 21147189; PMCID: PMC3068235.
    Citations: 59     Fields:    Translation:HumansCells
  24. Lin W, Wu G, Li S, Weinberg EM, Kumthip K, Peng LF, Méndez-Navarro J, Chen WC, Jilg N, Zhao H, Goto K, Zhang L, Brockman MA, Schuppan D, Chung RT. HIV and HCV cooperatively promote hepatic fibrogenesis via induction of reactive oxygen species and NFkappaB. J Biol Chem. 2011 Jan 28; 286(4):2665-74. PMID: 21098019.
    Citations: 60     Fields:    Translation:HumansCells
  25. Jang JY, Shao RX, Lin W, Weinberg E, Chung WJ, Tsai WL, Zhao H, Goto K, Zhang L, Mendez-Navarro J, Jilg N, Peng LF, Brockman MA, Chung RT. HIV infection increases HCV-induced hepatocyte apoptosis. J Hepatol. 2011 Apr; 54(4):612-20. PMID: 21146890.
    Citations: 28     Fields:    Translation:HumansCells
  26. Hoffmann M, Zeisel MB, Jilg N, Paranhos-Baccalà G, Stoll-Keller F, Wakita T, Hafkemeyer P, Blum HE, Barth H, Henneke P, Baumert TF. Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles. J Innate Immun. 2009; 1(5):446-54. PMID: 20375602.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  27. Thoden J, Venhoff N, Miehle N, Klar M, Huzly D, Panther E, Jilg N, Kunze M, Warnatz K. Hepatitis E and jaundice in an HIV-positive pregnant woman. AIDS. 2008 Apr 23; 22(7):909-10. PMID: 18427215.
    Citations: 12     Fields:    Translation:Humans
  28. Quirling M, Page S, Jilg N, Plenagl K, Peus D, Grubmüller C, Weingärtner M, Fischer C, Neumeier D, Brand K. Detection of IKKbeta-IKKgamma subcomplexes in monocytic cells and characterization of associated signaling. J Biol Chem. 2004 Sep 03; 279(36):37452-60. PMID: 15226300.
    Citations: 4     Fields:    Translation:HumansCells
  29. Bell S, Degitz K, Quirling M, Jilg N, Page S, Brand K. Involvement of NF-kappaB signalling in skin physiology and disease. Cell Signal. 2003 Jan; 15(1):1-7. PMID: 12401514.
    Citations: 43     Fields:    Translation:AnimalsCells
  30. Donath B, Fischer C, Page S, Prebeck S, Jilg N, Weber M, da Costa C, Neumeier D, Miethke T, Brand K. Chlamydia pneumoniae activates IKK/I kappa B-mediated signaling, which is inhibited by 4-HNE and following primary exposure. Atherosclerosis. 2002 Nov; 165(1):79-88. PMID: 12208473.
    Citations: 15     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.