Harvard Catalyst Profiles

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Thomas Elliott Van Dyke, Ph.D., D.D.S.

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Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R90DE027638 (VAN DYKE, THOMAS E) Jul 1, 2017 - Jun 30, 2022
    NIH/NIDCR
    Forsyth Postdoctoral Training in Oral Health Research
    Role: Principal Investigator
  2. T90DE026110 (VAN DYKE, THOMAS E) Jul 1, 2017 - Jun 30, 2022
    NIH/NIDCR
    Forsyth Postdoctoral Training in Oral Health Research
    Role: Principal Investigator
  3. U01DE026934 (VAN DYKE, THOMAS E) Sep 23, 2016 - Aug 31, 2018
    NIH/NIDCR
    Phase 1/2 Clinical Trial to assess the safety and preliminary efficacy of Lipoxin Analog BLXA4-MEOral Rinse for the Treatment of Gingivitis
    Role: Co-Principal Investigator
  4. R01DE025383 (NIKOLAJCZYK, BARBARA) Jul 1, 2016 - Jun 30, 2021
    NIH/NIDCR
    Roles for lymphocyte RANKL in periodontal complications of type 2 diabetes
    Role: Co-Principal Investigator
  5. R01DE025020 (VAN DYKE, THOMAS E) May 1, 2015 - Jun 30, 2024
    NIH/NIDCR
    Mechanisms of Pro-Resolving Mediators in Periodontal Regeneration
    Role: Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Shinjo T, Ishikado A, Hasturk H, Pober DM, Paniagua SM, Shah H, Wu IH, Tinsley LJ, Matsumoto M, Keenan HA, Van Dyke TE, Genco RJ, King GL. Characterization of periodontitis in people with type 1 diabetes of 50 years or longer duration. J Periodontol. 2019 Jun; 90(6):565-575. PMID: 31026349.
    Citations:    
  2. Van Dyke TE. Robert J. Genco, DDS, PhD: Legacy of a renowned and visionary periodontal researcher who shaped our knowledge of periodontitis and systemic diseases. J Periodontol. 2019 Jun; 90(6):563-564. PMID: 31081185.
    Citations:    
  3. Montero E, Herrera D, Sanz M, Dhir S, Van Dyke T, Sima C. Development and validation of a predictive model for periodontitis using NHANES 2011-2012 data. J Clin Periodontol. 2019 Apr; 46(4):420-429. PMID: 30891834.
    Citations:    
  4. Siddiqui YD, Omori K, Ito T, Yamashiro K, Nakamura S, Okamoto K, Ono M, Yamamoto T, Van Dyke TE, Takashiba S. Resolvin D2 Induces Resolution of Periapical Inflammation and Promotes Healing of Periapical Lesions in Rat Periapical Periodontitis. Front Immunol. 2019; 10:307. PMID: 30863409.
    Citations:    
  5. Bartold PM, Van Dyke TE. An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis. J Clin Periodontol. 2019 Jan; 46(1):6-11. PMID: 30556922.
    Citations:    Fields:    
  6. Mendes RT, Nguyen D, Stephens D, Pamuk F, Fernandes D, Hasturk H, Van Dyke TE, Kantarci A. Hypoxia-induced endothelial cell responses - possible roles during periodontal disease. Clin Exp Dent Res. 2018 Dec; 4(6):241-248. PMID: 30603105.
    Citations:    
  7. El Kholy K, Freire M, Chen T, Van Dyke TE. Resolvin E1 Promotes Bone Preservation Under Inflammatory Conditions. Front Immunol. 2018; 9:1300. PMID: 29946319.
    Citations:    
  8. Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol. 2018 Jun; 45 Suppl 20:S68-S77. PMID: 29926499.
    Citations: 2     Fields:    
  9. Chapple ILC, Mealey BL, Van Dyke TE, Bartold PM, Dommisch H, Eickholz P, Geisinger ML, Genco RJ, Glogauer M, Goldstein M, Griffin TJ, Holmstrup P, Johnson GK, Kapila Y, Lang NP, Meyle J, Murakami S, Plemons J, Romito GA, Shapira L, Tatakis DN, Teughels W, Trombelli L, Walter C, Wimmer G, Xenoudi P, Yoshie H. Periodontal health and gingival diseases and conditions on an intact and a reduced periodontium: Consensus report of workgroup 1 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol. 2018 Jun; 89 Suppl 1:S74-S84. PMID: 29926944.
    Citations:    Fields:    
  10. Mizraji G, Heyman O, Van Dyke TE, Wilensky A. Resolvin D2 Restrains Th1 Immunity and Prevents Alveolar Bone Loss in Murine Periodontitis. Front Immunol. 2018; 9:785. PMID: 29922275.
    Citations:    
  11. Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE. Author Correction: ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance. Sci Rep. 2018 Mar 02; 8(1):4143. PMID: 29500456.
    Citations:    Fields:    
  12. Sima C, Paster B, Van Dyke TE. Function of Pro-Resolving Lipid Mediator Resolvin E1 in Type 2 Diabetes. Crit Rev Immunol. 2018; 38(5):343-365. PMID: 30806214.
    Citations:    
  13. Hamilton JA, Hasturk H, Kantarci A, Serhan CN, Van Dyke T. Atherosclerosis, Periodontal Disease, and Treatment with Resolvins. Curr Atheroscler Rep. 2017 Nov 06; 19(12):57. PMID: 29110146.
    Citations: 1     Fields:    Translation:HumansAnimals
  14. Manosudprasit A, Kantarci A, Hasturk H, Stephens D, Van Dyke TE. Spontaneous PMN apoptosis in type 2 diabetes and the impact of periodontitis. J Leukoc Biol. 2017 12; 102(6):1431-1440. PMID: 29021368.
    Citations:    Fields:    Translation:HumansCells
  15. Sima C, Montero E, Nguyen D, Freire M, Norris P, Serhan CN, Van Dyke TE. ERV1 Overexpression in Myeloid Cells Protects against High Fat Diet Induced Obesity and Glucose Intolerance. Sci Rep. 2017 10 09; 7(1):12848. PMID: 28993702.
    Citations:    Fields:    
  16. Hamilton J, Hasturk H, Kantarci A, Van Dyke T, Phinikaridou A. Atherothrombosis: Resolution of vessel wall inflammation and limitation of thrombosis and thrombus propagation by resolvins. Atherosclerosis. 2017 Aug; 263:e144-e145. PMID: 29365572.
    Citations:    Fields:    
  17. Naqvi AZ, Mu L, Hasturk H, Van Dyke TE, Mukamal KJ, Goodson JM. Impact of Docosahexaenoic Acid Therapy on Subgingival Plaque Microbiota. J Periodontol. 2017 09; 88(9):887-895. PMID: 28517974.
    Citations: 1     Fields:    Translation:Humans
  18. Van Dyke TE. Pro-resolving mediators in the regulation of periodontal disease. Mol Aspects Med. 2017 Dec; 58:21-36. PMID: 28483532.
    Citations: 6     Fields:    Translation:HumansAnimals
  19. Mohamed Ali H, Berggreen E, Nguyen D, Wahab Ali R, Van Dyke TE, Hasturk H, Mustafa M. Dental plaque microbial profiles of children from Khartoum, Sudan, with congenital heart defects. J Oral Microbiol. 2017; 9(1):1281556. PMID: 28326155.
    Citations:    
  20. Freire MO, Dalli J, Serhan CN, Van Dyke TE. Neutrophil Resolvin E1 Receptor Expression and Function in Type 2 Diabetes. J Immunol. 2017 01 15; 198(2):718-728. PMID: 27994073.
    Citations: 4     Fields:    Translation:HumansCells
  21. Konermann A, Van Dyke T, Kantarci A, Jäger A. GABAB Receptors as Modulating Target for Inflammatory Responses of the Periodontal Ligament. Cell Mol Neurobiol. 2017 Aug; 37(6):1067-1076. PMID: 27812916.
    Citations: 1     Fields:    Translation:HumansCells
  22. Kurgan S, Kansal S, Nguyen D, Stephens D, Koroneos Y, Hasturk H, Van Dyke TE, Kantarci A. Strain-Specific Impact of Fusobacterium nucleatum on Neutrophil Function. J Periodontol. 2017 04; 88(4):380-389. PMID: 27762731.
    Citations: 2     Fields:    Translation:HumansCells
  23. Lee CT, Teles R, Kantarci A, Chen T, McCafferty J, Starr JR, Brito LC, Paster BJ, Van Dyke TE. Resolvin E1 Reverses Experimental Periodontitis and Dysbiosis. J Immunol. 2016 10 01; 197(7):2796-806. PMID: 27543615.
    Citations: 10     Fields:    Translation:Animals
  24. El-Sharkawy HM, Anees MM, Van Dyke TE. Propolis Improves Periodontal Status and Glycemic Control in Patients With Type 2 Diabetes Mellitus and Chronic Periodontitis: A Randomized Clinical Trial. J Periodontol. 2016 Dec; 87(12):1418-1426. PMID: 27468795.
    Citations:    
  25. Mendes RT, Nguyen D, Stephens D, Pamuk F, Fernandes D, Van Dyke TE, Kantarci A. Endothelial Cell Response to Fusobacterium nucleatum. Infect Immun. 2016 07; 84(7):2141-2148. PMID: 27185790.
    Citations: 1     Fields:    Translation:HumansCells
  26. Movila A, Ishii T, Albassam A, Wisitrasameewong W, Howait M, Yamaguchi T, Ruiz-Torruella M, Bahammam L, Nishimura K, Van Dyke T, Kawai T. Macrophage Migration Inhibitory Factor (MIF) Supports Homing of Osteoclast Precursors to Peripheral Osteolytic Lesions. J Bone Miner Res. 2016 09; 31(9):1688-700. PMID: 27082509.
    Citations: 4     Fields:    Translation:AnimalsCells
  27. Konermann A, Kantarci A, Wilbert S, Van Dyke T, Jäger A. Verification of ?-Amino-Butyric Acid (GABA) Signaling System Components in Periodontal Ligament Cells In Vivo and In Vitro. Cell Mol Neurobiol. 2016 Nov; 36(8):1353-1363. PMID: 26865191.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  28. Sima C, Van Dyke TE. Therapeutic Targets for Management of Periodontitis and Diabetes. Curr Pharm Des. 2016; 22(15):2216-37. PMID: 26881443.
    Citations: 2     Fields:    Translation:Humans
  29. Zamakhchari MF, Sima C, Sama K, Fine N, Glogauer M, Van Dyke TE, Gyurko R. Lack of p47(phox) in Akita Diabetic Mice Is Associated with Interstitial Pneumonia, Fibrosis, and Oral Inflammation. Am J Pathol. 2016 Mar; 186(3):659-70. PMID: 26747235.
    Citations: 1     Fields:    Translation:AnimalsCells
  30. Wang CW, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE, Serhan CN. Maresin 1 Biosynthesis and Proresolving Anti-infective Functions with Human-Localized Aggressive Periodontitis Leukocytes. Infect Immun. 2015 Dec 14; 84(3):658-65. PMID: 26667839.
    Citations: 9     Fields:    Translation:HumansCells
  31. Steffens JP, Coimbra LS, Rossa C, Kantarci A, Van Dyke TE, Spolidorio LC. Androgen receptors and experimental bone loss - an in vivo and in vitro study. Bone. 2015 Dec; 81:683-690. PMID: 26450018.
    Citations: 1     Fields:    Translation:AnimalsCells
  32. Maekawa T, Hosur K, Abe T, Kantarci A, Ziogas A, Wang B, Van Dyke TE, Chavakis T, Hajishengallis G. Antagonistic effects of IL-17 and D-resolvins on endothelial Del-1 expression through a GSK-3ß-C/EBPß pathway. Nat Commun. 2015 Sep 16; 6:8272. PMID: 26374165.
    Citations: 21     Fields:    Translation:HumansAnimalsCells
  33. Kang EH, Lee JT, Lee HJ, Lee JY, Chang SH, Cho HJ, Choi BY, Ha YJ, Park KU, Song YW, Van Dyke TE, Lee YJ. Chronic Periodontitis Is Associated With Spinal Dysmobility in Patients With Ankylosing Spondylitis. J Periodontol. 2015 Dec; 86(12):1303-13. PMID: 26291296.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  34. Herrera BS, Kantarci A, Zarrough A, Hasturk H, Leung KP, Van Dyke TE. LXA4 actions direct fibroblast function and wound closure. Biochem Biophys Res Commun. 2015 Sep 04; 464(4):1072-1077. PMID: 26188508.
    Citations: 5     Fields:    Translation:AnimalsCells
  35. Steffens JP, Wang X, Starr JR, Spolidorio LC, Van Dyke TE, Kantarci A. Associations Between Sex Hormone Levels and Periodontitis in Men: Results From NHANES III. J Periodontol. 2015 Oct; 86(10):1116-25. PMID: 26062840.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  36. Kantarci A, Hasturk H, Van Dyke TE. Animal models for periodontal regeneration and peri-implant responses. Periodontol 2000. 2015 Jun; 68(1):66-82. PMID: 25867980.
    Citations: 2     Fields:    Translation:HumansAnimals
  37. Kholy KE, Genco RJ, Van Dyke TE. Oral infections and cardiovascular disease. Trends Endocrinol Metab. 2015 Jun; 26(6):315-21. PMID: 25892452.
    Citations: 19     Fields:    Translation:Humans
  38. Hasturk H, Abdallah R, Kantarci A, Nguyen D, Giordano N, Hamilton J, Van Dyke TE. Resolvin E1 (RvE1) Attenuates Atherosclerotic Plaque Formation in Diet and Inflammation-Induced Atherogenesis. Arterioscler Thromb Vasc Biol. 2015 May; 35(5):1123-33. PMID: 25792445.
    Citations: 32     Fields:    Translation:Animals
  39. Herrera BS, Hasturk H, Kantarci A, Freire MO, Nguyen O, Kansal S, Van Dyke TE. Impact of resolvin E1 on murine neutrophil phagocytosis in type 2 diabetes. Infect Immun. 2015 Feb; 83(2):792-801. PMID: 25486994.
    Citations: 16     Fields:    Translation:AnimalsCells
  40. Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J, Serhan CN. Proresolving nanomedicines activate bone regeneration in periodontitis. J Dent Res. 2015 Jan; 94(1):148-56. PMID: 25389003.
    Citations: 21     Fields:    Translation:Animals
  41. Ayilavarapu S, Kantarci A, Hasturk H, Van Dyke TE. IPLA2 mRNA expression by human neutrophils in type 2 diabetes and chronic periodontitis. J Int Acad Periodontol. 2014 Oct; 16(4):121-6. PMID: 25654966.
    Citations: 1     Fields:    Translation:HumansCells
  42. Martin CR, Zaman MM, Gilkey C, Salguero MV, Hasturk H, Kantarci A, Van Dyke TE, Freedman SD. Resolvin D1 and lipoxin A4 improve alveolarization and normalize septal wall thickness in a neonatal murine model of hyperoxia-induced lung injury. PLoS One. 2014; 9(6):e98773. PMID: 24892762.
    Citations: 15     Fields:    Translation:Animals
  43. Borgnakke WS, Chapple IL, Genco RJ, Armitage G, Bartold PM, D'Aiuto F, Eke PI, Giannobile WV, Kocher T, Kornman KS, Lang NP, Madianos PN, Murakami S, Nishimura F, Offenbacher S, Preshaw PM, Rahman AU, Sanz M, Slots J, Tonetti MS, Van Dyke TE. The multi-center randomized controlled trial (RCT) published by the journal of the American Medical Association (JAMA) on the effect of periodontal therapy on glycated hemoglobin (HbA1c) has fundamental problems. J Evid Based Dent Pract. 2014 Sep; 14(3):127-32. PMID: 25234213.
    Citations: 10     Fields:    Translation:Humans
  44. Van Dyke TE. Commentary: periodontitis is characterized by an immuno-inflammatory host-mediated destruction of bone and connective tissues that support the teeth. J Periodontol. 2014 Apr; 85(4):509-11. PMID: 24678865.
    Citations: 5     Fields:    Translation:HumansCells
  45. Scarparo RK, Dondoni L, Böttcher DE, Grecca FS, Figueiredo JA, Kantarci A, Van Dyke TE, Batista EL. Intracanal delivery of Resolvin E1 controls inflammation in necrotic immature rat teeth. J Endod. 2014 May; 40(5):678-82. PMID: 24767563.
    Citations:    Fields:    Translation:Animals
  46. Hasturk H, Kantarci A, Ghattas M, Dangaria SJ, Abdallah R, Morgan EF, Diekwisch TG, Ashman A, Van Dyke T. The use of light/chemically hardened polymethylmethacrylate, polyhydroxylethylmethacrylate, and calcium hydroxide graft material in combination with polyanhydride around implants and extraction sockets in minipigs: Part II: histologic and micro-CT evaluations. J Periodontol. 2014 Sep; 85(9):1230-9. PMID: 24502615.
    Citations:    Fields:    Translation:AnimalsPHPublic Health
  47. Cekici A, Kantarci A, Hasturk H, Van Dyke TE. Inflammatory and immune pathways in the pathogenesis of periodontal disease. Periodontol 2000. 2014 Feb; 64(1):57-80. PMID: 24320956.
    Citations: 68     Fields:    Translation:HumansCells
  48. Gao A, Van Dyke TE. Role of suppressors of cytokine signaling 3 in bone inflammatory responses. Front Immunol. 2014 Jan 10; 4:506. PMID: 24454312.
    Citations: 1     
  49. Gyurko R, Van Dyke TE. The role of polyunsaturated ?-3 fatty acid eicosapentaenoic acid-derived resolvin E1 (RvE1) in bone preservation. Crit Rev Immunol. 2014; 34(4):347-57. PMID: 24941160.
    Citations: 5     Fields:    Translation:HumansAnimals
  50. Van Dyke TE, Starr JR. Unraveling the link between periodontitis and cardiovascular disease. J Am Heart Assoc. 2013 Dec 16; 2(6):e000657. PMID: 24342998.
    Citations: 2     Fields:    Translation:Humans
  51. Janket SJ, Baird AE, Jones JA, Jackson EA, Surakka M, Tao W, Meurman JH, Van Dyke TE. Number of teeth, C-reactive protein, fibrinogen and cardiovascular mortality: a 15-year follow-up study in a Finnish cohort. J Clin Periodontol. 2014 Feb; 41(2):131-40. PMID: 24354534.
    Citations: 4     Fields:    Translation:Humans
  52. Zenobia C, Hasturk H, Nguyen D, Van Dyke TE, Kantarci A, Darveau RP. Porphyromonas gingivalis lipid A phosphatase activity is critical for colonization and increasing the commensal load in the rabbit ligature model. Infect Immun. 2014 Feb; 82(2):650-9. PMID: 24478080.
    Citations: 16     Fields:    Translation:AnimalsCells
  53. Batista EL, Kantarci AI, Hasturk H, Van Dyke TE. Alternative splicing generates a diacylglycerol kinase a transcript that acts as a dominant-negative modulator of superoxide production in localized aggressive periodontitis. J Periodontol. 2014 Jul; 85(7):934-43. PMID: 24171497.
    Citations:    Fields:    Translation:HumansAnimalsCells
  54. Freire MO, Van Dyke TE. Natural resolution of inflammation. Periodontol 2000. 2013 Oct; 63(1):149-64. PMID: 23931059.
    Citations: 27     Fields:    Translation:HumansCells
  55. Herrera BS, Bastos AS, Coimbra LS, Teixeira SA, Rossa C, Van Dyke TE, Muscara MN, Spolidorio LC. Peripheral blood mononuclear phagocytes from patients with chronic periodontitis are primed for osteoclast formation. J Periodontol. 2014 Apr; 85(4):e72-81. PMID: 24059638.
    Citations: 5     Fields:    Translation:HumansCells
  56. Hasturk H, Nguyen DH, Sherzai H, Song X, Soukos N, Bidlack FB, Van Dyke TE. Comparison of the impact of scaler material composition on polished titanium implant abutment surfaces. J Dent Hyg. 2013 Aug; 87(4):200-11. PMID: 23986413.
    Citations: 2     Fields:    Translation:Humans
  57. Mustafa M, Zarrough A, Bolstad AI, Lygre H, Mustafa K, Hasturk H, Serhan C, Kantarci A, Van Dyke TE. Resolvin D1 protects periodontal ligament. Am J Physiol Cell Physiol. 2013 Sep 15; 305(6):C673-9. PMID: 23864609.
    Citations: 11     Fields:    Translation:HumansCells
  58. Bartold PM, Van Dyke TE. Periodontitis: a host-mediated disruption of microbial homeostasis. Unlearning learned concepts. Periodontol 2000. 2013 Jun; 62(1):203-17. PMID: 23574467.
    Citations: 45     Fields:    Translation:Humans
  59. Socransky SS, Haffajee AD, Teles R, Wennstrom JL, Lindhe J, Bogren A, Hasturk H, van Dyke T, Wang X, Goodson JM. Effect of periodontal therapy on the subgingival microbiota over a 2-year monitoring period. I. Overall effect and kinetics of change. J Clin Periodontol. 2013 Aug; 40(8):771-80. PMID: 23710672.
    Citations: 11     Fields:    Translation:HumansCells
  60. Zhu M, Van Dyke TE, Gyurko R. Resolvin E1 regulates osteoclast fusion via DC-STAMP and NFATc1. FASEB J. 2013 Aug; 27(8):3344-53. PMID: 23629863.
    Citations: 6     Fields:    Translation:AnimalsCells
  61. Browne RW, Kantarci A, LaMonte MJ, Andrews CA, Hovey KM, Falkner KL, Cekici A, Stephens D, Genco RJ, Scannapieco FA, Van Dyke TE, Wactawski-Wende J. Performance of multiplex cytokine assays in serum and saliva among community-dwelling postmenopausal women. PLoS One. 2013; 8(4):e59498. PMID: 23577067.
    Citations: 11     Fields:    Translation:Humans
  62. Tonetti MS, Van Dyke TE. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Periodontol. 2013 Apr; 84(4 Suppl):S24-9. PMID: 23631582.
    Citations: 45     Fields:    Translation:HumansAnimals
  63. Van Dyke TE, van Winkelhoff AJ. Infection and inflammatory mechanisms. J Clin Periodontol. 2013 Apr; 40 Suppl 14:S1-7. PMID: 23627321.
    Citations: 11     Fields:    Translation:HumansAnimals
  64. Tonetti MS, Van Dyke TE. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAP Workshop on Periodontitis and Systemic Diseases. J Clin Periodontol. 2013 Apr; 40 Suppl 14:S24-9. PMID: 23627332.
    Citations: 35     Fields:    Translation:HumansAnimals
  65. Van Dyke TE, van Winkelhoff AJ. Infection and inflammatory mechanisms. J Periodontol. 2013 Apr; 84(4 Suppl):S1-7. PMID: 23631571.
    Citations: 14     Fields:    Translation:HumansAnimals
  66. Tonetti MS, Van Dyke TE. Periodontitis and atherosclerotic cardiovascular disease: consensus report of the Joint EFP/AAPWorkshop on Periodontitis and Systemic Diseases. J Periodontol. 2013 Apr; 84 Suppl 4S:S24-S29. PMID: 29537596.
    Citations: 1     Fields:    
  67. Gao A, Kantarci A, Herrera BS, Gao H, Van Dyke TE. Correction: A critical role for suppressors of cytokine signaling 3 in regulating LPS-induced transcriptional activation of matrix metalloproteinase-13 in osteoblasts. PeerJ. 2013; 1. PMID: 24191232.
    Citations:    
  68. Gao A, Kantarci A, Herrera BS, Herrera B, Gao H, Van Dyke TE. A critical role for suppressors of cytokine signaling 3 in regulating LPS-induced transcriptional activation of matrix metalloproteinase-13 in osteoblasts. PeerJ. 2013; 1:e51. PMID: 23638389.
    Citations: 9     
  69. Gao L, Faibish D, Fredman G, Herrera BS, Chiang N, Serhan CN, Van Dyke TE, Gyurko R. Resolvin E1 and chemokine-like receptor 1 mediate bone preservation. J Immunol. 2013 Jan 15; 190(2):689-94. PMID: 23241890.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  70. Berker E, Kantarci A, Hasturk H, Van Dyke TE. Blocking proinflammatory cytokine release modulates peripheral blood mononuclear cell response to Porphyromonas gingivalis. J Periodontol. 2013 Sep; 84(9):1337-45. PMID: 23173823.
    Citations: 3     Fields:    Translation:HumansCells
  71. Gao L, Cyurko R, Van Dyke T. [Attenuation of experimental peritonitis and periodontitis in human chemokine-like receptor 1 (CMKLR1 or hChemR23) transgenic mice]. Beijing Da Xue Xue Bao Yi Xue Ban. 2012 Jun 18; 44(3):469-74. PMID: 22692323.
    Citations:    Fields:    Translation:AnimalsCells
  72. Hasturk H, Kantarci A, Van Dyke TE. Oral inflammatory diseases and systemic inflammation: role of the macrophage. Front Immunol. 2012; 3:118. PMID: 22623923.
    Citations: 29     
  73. Goodson JM, Haffajee AD, Socransky SS, Kent R, Teles R, Hasturk H, Bogren A, Van Dyke T, Wennstrom J, Lindhe J. Control of periodontal infections: a randomized controlled trial I. The primary outcome attachment gain and pocket depth reduction at treated sites. J Clin Periodontol. 2012 Jun; 39(6):526-36. PMID: 22512461.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  74. Rocha Dde M, Zenóbio EG, Van Dyke T, Silva KS, Costa FO, Soares RV. Differential expression of salivary glycoproteins in aggressive and chronic periodontitis. J Appl Oral Sci. 2012 Mar-Apr; 20(2):180-5. PMID: 22666834.
    Citations: 4     Fields:    Translation:Humans
  75. Colombo AP, Bennet S, Cotton SL, Goodson JM, Kent R, Haffajee AD, Socransky SS, Hasturk H, Van Dyke TE, Dewhirst FE, Paster BJ. Impact of periodontal therapy on the subgingival microbiota of severe periodontitis: comparison between good responders and individuals with refractory periodontitis using the human oral microbe identification microarray. J Periodontol. 2012 Oct; 83(10):1279-87. PMID: 22324467.
    Citations: 49     Fields:    Translation:HumansCells
  76. Van Dyke TE. The impact of genotypes and immune reactivity on peri-implant inflammation: Identification and therapeutic use of anti-inflammatory drugs and immunomodulators. Eur J Oral Implantol. 2012; 5 Suppl:S51-60. PMID: 22834394.
    Citations: 1     Fields:    Translation:Humans
  77. Hasturk H, Kantarci A, Van Dyke TE. Paradigm shift in the pharmacological management of periodontal diseases. Front Oral Biol. 2012; 15:160-76. PMID: 22142963.
    Citations: 16     Fields:    Translation:HumansCells
  78. Karima MM, Van Dyke TE. Enamel matrix derivative promotes superoxide production and chemotaxis but reduces matrix metalloproteinase-8 expression by polymorphonuclear leukocytes. J Periodontol. 2012 Jun; 83(6):780-6. PMID: 22050547.
    Citations: 2     Fields:    Translation:HumansCells
  79. Fredman G, Oh SF, Ayilavarapu S, Hasturk H, Serhan CN, Van Dyke TE. Impaired phagocytosis in localized aggressive periodontitis: rescue by Resolvin E1. PLoS One. 2011; 6(9):e24422. PMID: 21935407.
    Citations: 46     Fields:    Translation:HumansCells
  80. Baloul SS, Gerstenfeld LC, Morgan EF, Carvalho RS, Van Dyke TE, Kantarci A. Mechanism of action and morphologic changes in the alveolar bone in response to selective alveolar decortication-facilitated tooth movement. Am J Orthod Dentofacial Orthop. 2011 Apr; 139(4 Suppl):S83-101. PMID: 21435543.
    Citations: 23     Fields:    Translation:AnimalsCells
  81. Herrera BS, Martins-Porto R, Maia-Dantas A, Campi P, Spolidorio LC, Costa SK, Van Dyke TE, Gyurko R, Muscara MN. iNOS-derived nitric oxide stimulates osteoclast activity and alveolar bone loss in ligature-induced periodontitis in rats. J Periodontol. 2011 Nov; 82(11):1608-15. PMID: 21417589.
    Citations: 10     Fields:    Translation:AnimalsCells
  82. Van Dyke TE. Proresolving lipid mediators: potential for prevention and treatment of periodontitis. J Clin Periodontol. 2011 Mar; 38 Suppl 11:119-25. PMID: 21323709.
    Citations: 16     Fields:    Translation:HumansAnimals
  83. Hasturk H, Kantarci A, Ghattas M, Schmidt M, Giordano RA, Ashman A, Diekwisch TG, Van Dyke T. The use of light/chemically hardened polymethylmethacrylate, polyhydroxyethylmethacrylate, and calcium hydroxide graft material in combination with polyanhydride around implants in minipigs: part I: immediate stability and function. J Periodontol. 2011 Sep; 82(9):1339-52. PMID: 21342001.
    Citations: 3     Fields:    Translation:Animals
  84. Price AM, Nunn M, Oppenheim FG, Van Dyke TE. De novo bone formation after the sinus lift procedure. J Periodontol. 2011 Sep; 82(9):1245-55. PMID: 21235336.
    Citations:    Fields:    Translation:HumansCells
  85. Stashenko P, Van Dyke T, Tully P, Kent R, Sonis S, Tanner AC. Inflammation and genetic risk indicators for early periodontitis in adults. J Periodontol. 2011 Apr; 82(4):588-96. PMID: 21054222.
    Citations: 5     Fields:    Translation:Humans
  86. Herrera BS, Martins-Porto R, Campi P, Holzhausen M, Teixeira SA, Mendes GD, Costa SK, Gyurko R, Van Dyke TE, Spolidório LC, Muscará MN. Local and cardiorenal effects of periodontitis in nitric oxide-deficient hypertensive rats. Arch Oral Biol. 2011 Jan; 56(1):41-7. PMID: 20864089.
    Citations: 5     Fields:    Translation:Animals
  87. Genco RJ, Van Dyke TE. Prevention: Reducing the risk of CVD in patients with periodontitis. Nat Rev Cardiol. 2010 Sep; 7(9):479-80. PMID: 20725103.
    Citations: 38     Fields:    Translation:Humans
  88. Fredman G, Van Dyke TE, Serhan CN. Resolvin E1 regulates adenosine diphosphate activation of human platelets. Arterioscler Thromb Vasc Biol. 2010 Oct; 30(10):2005-13. PMID: 20702811.
    Citations: 38     Fields:    Translation:HumansAnimalsCells
  89. Qvarnstrom M, Janket SJ, Jones JA, Jethwani K, Nuutinen P, Garcia RI, Baird AE, Van Dyke TE, Meurman JH. Association of salivary lysozyme and C-reactive protein with metabolic syndrome. J Clin Periodontol. 2010 Sep; 37(9):805-11. PMID: 20666873.
    Citations: 5     Fields:    Translation:Humans
  90. El-Sharkawy H, Aboelsaad N, Eliwa M, Darweesh M, Alshahat M, Kantarci A, Hasturk H, Van Dyke TE. Adjunctive treatment of chronic periodontitis with daily dietary supplementation with omega-3 Fatty acids and low-dose aspirin. J Periodontol. 2010 Nov; 81(11):1635-43. PMID: 20572767.
    Citations: 28     Fields:    Translation:HumansPHPublic Health
  91. de Santana RB, de Mattos CM, Francischone CE, Van Dyke T. Superficial topography and porosity of an absorbable barrier membrane impacts soft tissue response in guided bone regeneration. J Periodontol. 2010 Jun; 81(6):926-33. PMID: 20380512.
    Citations: 3     Fields:    Translation:AnimalsCells
  92. Ayilavarapu S, Kantarci A, Fredman G, Turkoglu O, Omori K, Liu H, Iwata T, Yagi M, Hasturk H, Van Dyke TE. Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils. J Immunol. 2010 Feb 01; 184(3):1507-15. PMID: 20053941.
    Citations: 23     Fields:    Translation:HumansCells
  93. Jagannathan M, Hasturk H, Liang Y, Shin H, Hetzel JT, Kantarci A, Rubin D, McDonnell ME, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients. J Immunol. 2009 Dec 01; 183(11):7461-70. PMID: 19917698.
    Citations: 30     Fields:    Translation:HumansCells
  94. Ohira T, Arita M, Omori K, Recchiuti A, Van Dyke TE, Serhan CN. Resolvin E1 receptor activation signals phosphorylation and phagocytosis. J Biol Chem. 2010 Jan 29; 285(5):3451-61. PMID: 19906641.
    Citations: 71     Fields:    Translation:HumansAnimalsCells
  95. Santana RB, de Mattos CM, Van Dyke T. Efficacy of combined regenerative treatments in human mandibular class II furcation defects. J Periodontol. 2009 Nov; 80(11):1756-64. PMID: 19905945.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  96. Colombo AP, Boches SK, Cotton SL, Goodson JM, Kent R, Haffajee AD, Socransky SS, Hasturk H, Van Dyke TE, Dewhirst F, Paster BJ. Comparisons of subgingival microbial profiles of refractory periodontitis, severe periodontitis, and periodontal health using the human oral microbe identification microarray. J Periodontol. 2009 Sep; 80(9):1421-32. PMID: 19722792.
    Citations: 164     Fields:    Translation:HumansCells
  97. Iwata T, Kantarci A, Yagi M, Jackson T, Hasturk H, Kurihara H, Van Dyke TE. Ceruloplasmin induces polymorphonuclear leukocyte priming in localized aggressive periodontitis. J Periodontol. 2009 Aug; 80(8):1300-6. PMID: 19656030.
    Citations: 5     Fields:    Translation:HumansCells
  98. Friedewald VE, Kornman KS, Beck JD, Genco R, Goldfine A, Libby P, Offenbacher S, Ridker PM, Van Dyke TE, Roberts WC. The American Journal of Cardiology and Journal of Periodontology Editors' Consensus: periodontitis and atherosclerotic cardiovascular disease. Am J Cardiol. 2009 Jul 01; 104(1):59-68. PMID: 19576322.
    Citations: 48     Fields:    Translation:Humans
  99. Friedewald VE, Kornman KS, Beck JD, Genco R, Goldfine A, Libby P, Offenbacher S, Ridker PM, Van Dyke TE, Roberts WC. The American Journal of Cardiology and Journal of Periodontology editors' consensus: periodontitis and atherosclerotic cardiovascular disease. J Periodontol. 2009 Jul; 80(7):1021-32. PMID: 19563277.
    Citations: 38     Fields:    Translation:Humans
  100. Dornelles FN, Santos DS, Van Dyke TE, Calixto JB, Batista EL, Campos MM. In vivo up-regulation of kinin B1 receptors after treatment with Porphyromonas gingivalis lipopolysaccharide in rat paw. J Pharmacol Exp Ther. 2009 Sep; 330(3):756-63. PMID: 19561153.
    Citations: 7     Fields:    Translation:AnimalsCells
  101. Van Dyke TE. Resolution of inflammation-unraveling mechanistic links between periodontitis and cardiovascular disease. J Dent. 2009 Aug; 37(8):S582-3. PMID: 19501948.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  102. Offenbacher S, Beck JD, Moss K, Mendoza L, Paquette DW, Barrow DA, Couper DJ, Stewart DD, Falkner KL, Graham SP, Grossi S, Gunsolley JC, Madden T, Maupome G, Trevisan M, Van Dyke TE, Genco RJ. Results from the Periodontitis and Vascular Events (PAVE) Study: a pilot multicentered, randomized, controlled trial to study effects of periodontal therapy in a secondary prevention model of cardiovascular disease. J Periodontol. 2009 Feb; 80(2):190-201. PMID: 19186958.
    Citations: 35     Fields:    Translation:HumansPHPublic Health
  103. Gapski R, Hasturk H, Van Dyke TE, Oringer RJ, Wang S, Braun TM, Giannobile WV. Systemic MMP inhibition for periodontal wound repair: results of a multi-centre randomized-controlled clinical trial. J Clin Periodontol. 2009 Feb; 36(2):149-56. PMID: 19207891.
    Citations: 13     Fields:    Translation:Humans
  104. Cobb CM, Costerton JW, Van Dyke TE. Have we become so focused on inflammation and host response that we have neglected the role of bacteria in initiating periodontal disease? Compend Contin Educ Dent. 2009 Jan-Feb; 30(1):46, 48. PMID: 19263764.
    Citations: 1     Fields:    Translation:Humans
  105. Van Dyke TE. The etiology and pathogenesis of periodontitis revisited. J Appl Oral Sci. 2009 Jan-Feb; 17(1). PMID: 19148397.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  106. Shin H, Zhang Y, Jagannathan M, Hasturk H, Kantarci A, Liu H, Van Dyke TE, Ganley-Leal LM, Nikolajczyk BS. B cells from periodontal disease patients express surface Toll-like receptor 4. J Leukoc Biol. 2009 Apr; 85(4):648-55. PMID: 19118102.
    Citations: 15     Fields:    Translation:HumansCells
  107. Shahidi P, Jacobson Z, Dibart S, Pourati J, Nunn ME, Barouch K, Van Dyke TE. Efficacy of a new papilla generation technique in implant dentistry: a preliminary study. Int J Oral Maxillofac Implants. 2008 Sep-Oct; 23(5):926-34. PMID: 19014164.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  108. Sebaoun JD, Kantarci A, Turner JW, Carvalho RS, Van Dyke TE, Ferguson DJ. Modeling of trabecular bone and lamina dura following selective alveolar decortication in rats. J Periodontol. 2008 Sep; 79(9):1679-88. PMID: 18771369.
    Citations: 15     Fields:    Translation:AnimalsCells
  109. Van Dyke TE, Kornman KS. Inflammation and factors that may regulate inflammatory response. J Periodontol. 2008 Aug; 79(8 Suppl):1503-7. PMID: 18673003.
    Citations: 11     Fields:    Translation:Humans
  110. Van Dyke TE. Inflammation and periodontal diseases: a reappraisal. J Periodontol. 2008 Aug; 79(8 Suppl):1501-2. PMID: 18673002.
    Citations: 3     Fields:    Translation:Humans
  111. Van Dyke TE. The management of inflammation in periodontal disease. J Periodontol. 2008 Aug; 79(8 Suppl):1601-8. PMID: 18673016.
    Citations: 42     Fields:    Translation:HumansAnimals
  112. Kornman KS, Van Dyke TE. Bringing light to the heat: "inflammation and periodontal diseases: a reappraisal". J Periodontol. 2008 Aug; 79(8):1313. PMID: 18672978.
    Citations: 3     Fields:    Translation:Humans
  113. Seabra RC, Costa FO, Costa JE, Van Dyke T, Soares RV. Impact of clinical experience on the accuracy of probing depth measurements. Quintessence Int. 2008 Jul-Aug; 39(7):559-65. PMID: 19107263.
    Citations: 1     Fields:    Translation:Humans
  114. Serhan CN, Chiang N, Van Dyke TE. Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators. Nat Rev Immunol. 2008 May; 8(5):349-61. PMID: 18437155.
    Citations: 704     Fields:    Translation:HumansAnimalsCells
  115. Omori K, Ohira T, Uchida Y, Ayilavarapu S, Batista EL, Yagi M, Iwata T, Liu H, Hasturk H, Kantarci A, Van Dyke TE. Priming of neutrophil oxidative burst in diabetes requires preassembly of the NADPH oxidase. J Leukoc Biol. 2008 Jul; 84(1):292-301. PMID: 18390927.
    Citations: 27     Fields:    Translation:HumansCells
  116. Graves DT, Fine D, Teng YT, Van Dyke TE, Hajishengallis G. The use of rodent models to investigate host-bacteria interactions related to periodontal diseases. J Clin Periodontol. 2008 Feb; 35(2):89-105. PMID: 18199146.
    Citations: 91     Fields:    Translation:HumansAnimalsCells
  117. Beck JD, Couper DJ, Falkner KL, Graham SP, Grossi SG, Gunsolley JC, Madden T, Maupome G, Offenbacher S, Stewart DD, Trevisan M, Van Dyke TE, Genco RJ. The Periodontitis and Vascular Events (PAVE) pilot study: adverse events. J Periodontol. 2008 Jan; 79(1):90-6. PMID: 18166097.
    Citations: 9     Fields:    Translation:HumansPHPublic Health
  118. Couper DJ, Beck JD, Falkner KL, Graham SP, Grossi SG, Gunsolley JC, Madden T, Maupome G, Offenbacher S, Stewart DD, Trevisan M, Van Dyke TE, Genco RJ. The Periodontitis and Vascular Events (PAVE) pilot study: recruitment, retention, and community care controls. J Periodontol. 2008 Jan; 79(1):80-9. PMID: 18166096.
    Citations: 8     Fields:    Translation:Humans
  119. Hasturk H, Kantarci A, Goguet-Surmenian E, Blackwood A, Andry C, Serhan CN, Van Dyke TE. Resolvin E1 regulates inflammation at the cellular and tissue level and restores tissue homeostasis in vivo. J Immunol. 2007 Nov 15; 179(10):7021-9. PMID: 17982093.
    Citations: 131     Fields:    Translation:AnimalsCells
  120. Zafiropoulos GG, Hoffmann O, Kasaj A, Willershausen B, Weiss O, Van Dyke TE. Treatment of intrabony defects using guided tissue regeneration and autogenous spongiosa alone or combined with hydroxyapatite/beta-tricalcium phosphate bone substitute or bovine-derived xenograft. J Periodontol. 2007 Nov; 78(11):2216-25. PMID: 17970691.
    Citations: 5     Fields:    Translation:HumansAnimals
  121. Zafiropoulos GK, Hoffmann O, Kasaj A, Willershausen B, Weiss O, Van Dyke TE. Treatment of Intrabony Defects Using Guided Tissue Regeneration and Autogenous Spongiosa Alone or Combined With Hydroxyapatite/ß-Tricalcium Phosphate Bone Substitute or Bovine-Derived Xenograft. J Periodontol. 2007 Nov; 78(11):2216-2225. PMID: 29539135.
    Citations:    Fields:    
  122. Janket SJ, Jones JA, Meurman JH, Baird AE, Van Dyke TE. Oral infection, hyperglycemia, and endothelial dysfunction. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 Feb; 105(2):173-9. PMID: 17905606.
    Citations: 24     Fields:    Translation:HumansCells
  123. Tanner AC, Kent R, Kanasi E, Lu SC, Paster BJ, Sonis ST, Murray LA, Van Dyke TE. Clinical characteristics and microbiota of progressing slight chronic periodontitis in adults. J Clin Periodontol. 2007 Nov; 34(11):917-30. PMID: 17877747.
    Citations: 18     Fields:    Translation:HumansCells
  124. Ding Y, Kantarci A, Badwey JA, Hasturk H, Malabanan A, Van Dyke TE. Phosphorylation of pleckstrin increases proinflammatory cytokine secretion by mononuclear phagocytes in diabetes mellitus. J Immunol. 2007 Jul 01; 179(1):647-54. PMID: 17579087.
    Citations: 15     Fields:    Translation:HumansCells
  125. Herrmann JM, Bernardo J, Long HJ, Seetoo K, McMenamin ME, Batista EL, Van Dyke TE, Simons ER. Sequential chemotactic and phagocytic activation of human polymorphonuclear neutrophils. Infect Immun. 2007 Aug; 75(8):3989-98. PMID: 17526745.
    Citations: 6     Fields:    Translation:HumansCells
  126. El-Sharkawy H, Kantarci A, Deady J, Hasturk H, Liu H, Alshahat M, Van Dyke TE. Platelet-rich plasma: growth factors and pro- and anti-inflammatory properties. J Periodontol. 2007 Apr; 78(4):661-9. PMID: 17397313.
    Citations: 76     Fields:    Translation:HumansCells
  127. Van Dyke TE. Cellular and molecular susceptibility determinants for periodontitis. Periodontol 2000. 2007; 45:10-3. PMID: 17850445.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  128. Van Dyke TE. Control of inflammation and periodontitis. Periodontol 2000. 2007; 45:158-66. PMID: 17850455.
    Citations: 22     Fields:    Translation:HumansAnimals
  129. Nassar H, Kantarci A, van Dyke TE. Diabetic periodontitis: a model for activated innate immunity and impaired resolution of inflammation. Periodontol 2000. 2007; 43:233-44. PMID: 17214841.
    Citations: 20     Fields:    Translation:HumansAnimals
  130. Gyurko R, Siqueira CC, Caldon N, Gao L, Kantarci A, Van Dyke TE. Chronic hyperglycemia predisposes to exaggerated inflammatory response and leukocyte dysfunction in Akita mice. J Immunol. 2006 Nov 15; 177(10):7250-6. PMID: 17082643.
    Citations: 28     Fields:    Translation:AnimalsCells
  131. Ding Y, Kantarci A, Hasturk H, Trackman PC, Malabanan A, Van Dyke TE. Activation of RAGE induces elevated O2- generation by mononuclear phagocytes in diabetes. J Leukoc Biol. 2007 Feb; 81(2):520-7. PMID: 17095613.
    Citations: 27     Fields:    Translation:HumansCells
  132. Ariel A, Fredman G, Sun YP, Kantarci A, Van Dyke TE, Luster AD, Serhan CN. Apoptotic neutrophils and T cells sequester chemokines during immune response resolution through modulation of CCR5 expression. Nat Immunol. 2006 Nov; 7(11):1209-16. PMID: 17013391.
    Citations: 114     Fields:    Translation:HumansAnimalsCells
  133. Janket SJ, Jones J, Rich S, Miller D, Wehler CJ, Van Dyke TE, Garcia R, Meurman JH. The effects of xerogenic medications on oral mucosa among the Veterans Dental Study participants. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2007 Feb; 103(2):223-30. PMID: 17234540.
    Citations: 2     Fields:    Translation:Humans
  134. Dillon S, Agrawal S, Banerjee K, Letterio J, Denning TL, Oswald-Richter K, Kasprowicz DJ, Kellar K, Pare J, van Dyke T, Ziegler S, Unutmaz D, Pulendran B. Yeast zymosan, a stimulus for TLR2 and dectin-1, induces regulatory antigen-presenting cells and immunological tolerance. J Clin Invest. 2006 Apr; 116(4):916-28. PMID: 16543948.
    Citations: 160     Fields:    Translation:HumansAnimalsCells
  135. Miyamoto T, Kumagai T, Jones JA, Van Dyke TE, Nunn ME. Compliance as a prognostic indicator: retrospective study of 505 patients treated and maintained for 15 years. J Periodontol. 2006 Feb; 77(2):223-32. PMID: 16460248.
    Citations: 10     Fields:    Translation:HumansPHPublic Health
  136. Janket SJ, Meurman JH, Nuutinen P, Qvarnström M, Nunn ME, Baird AE, Van Dyke TE, Jones JA. Salivary lysozyme and prevalent coronary heart disease: possible effects of oral health on endothelial dysfunction. Arterioscler Thromb Vasc Biol. 2006 Feb; 26(2):433-4. PMID: 16424364.
    Citations: 9     Fields:    Translation:HumansCells
  137. Kantarci A, Hasturk H, Van Dyke TE. Host-mediated resolution of inflammation in periodontal diseases. Periodontol 2000. 2006; 40:144-63. PMID: 16398691.
    Citations: 16     Fields:    Translation:Humans
  138. Kantarci A, Van Dyke TE. Resolution of inflammation in periodontitis. J Periodontol. 2005 Nov; 76(11 Suppl):2168-74. PMID: 16277590.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  139. Fujita T, Kantarci A, Warbington ML, Zawawi KH, Hasturk H, Kurihara H, Van Dyke TE. CD38 expression in neutrophils from patients with localized aggressive periodontitis. J Periodontol. 2005 Nov; 76(11):1960-5. PMID: 16274316.
    Citations: 2     Fields:    Translation:HumansCells
  140. Kantarci A, Van Dyke TE. Resolution of Inflammation in Periodontitis. J Periodontol. 2005 Nov; 76 Suppl 11S:2168-2174. PMID: 29539044.
    Citations:    Fields:    
  141. Gibson FC, Savelli J, Van Dyke TE, Genco CA. Gingipain-specific IgG in the sera of patients with periodontal disease is necessary for opsonophagocytosis of Porphyromonas gingivalis. J Periodontol. 2005 Oct; 76(10):1629-36. PMID: 16253083.
    Citations: 9     Fields:    Translation:HumansCells
  142. Van Dyke TE. The clinical significance of new therapies for the management of periodontal disease. J Int Acad Periodontol. 2005 Oct; 7(4 Suppl):191-6. PMID: 16248275.
    Citations: 2     Fields:    Translation:Humans
  143. Kantarci A, Van Dyke TE. Lipoxin signaling in neutrophils and their role in periodontal disease. Prostaglandins Leukot Essent Fatty Acids. 2005 Sep-Oct; 73(3-4):289-99. PMID: 15979867.
    Citations: 11     Fields:    Translation:HumansAnimalsCells
  144. Herrmann JM, Kantarci A, Long H, Bernardo J, Hasturk H, Wray LV, Simons ER, Van Dyke TE. Simultaneous measurements of cytoplasmic Ca2+ responses and intracellular pH in neutrophils of localized aggressive periodontitis (LAP) patients. J Leukoc Biol. 2005 Sep; 78(3):612-9. PMID: 15937144.
    Citations: 1     Fields:    Translation:HumansCells
  145. Berker E, Kantarci A, Hasturk H, Van Dyke TE. Effect of neutrophil apoptosis on monocytic cytokine response to Porphyromonas gingivalis lipopolysaccharide. J Periodontol. 2005 Jun; 76(6):964-71. PMID: 15948692.
    Citations: 2     Fields:    Translation:HumansCells
  146. Van Dyke TE, Cutler CW, Kowolik M, Singer RS, Buchanan W, Biesbrock AR. Effect of topical cimetidine rinse on gingival crevicular neutrophil leukocyte function. J Periodontol. 2005 Jun; 76(6):998-1005. PMID: 15948697.
    Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
  147. Litkowski LJ, Christensen SE, Adamson DN, Van Dyke T, Han SH, Newman KB. Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blind, placebo-controlled, single-dose, parallel-group study in a dental pain model. Clin Ther. 2005 Apr; 27(4):418-29. PMID: 15922815.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  148. Tanner AC, Kent R, Van Dyke T, Sonis ST, Murray LA. Clinical and other risk indicators for early periodontitis in adults. J Periodontol. 2005 Apr; 76(4):573-81. PMID: 15857098.
    Citations: 13     Fields:    Translation:HumansPHPublic Health
  149. Batista EL, Warbington M, Badwey JA, Van Dyke TE. Differentiation of HL-60 cells to granulocytes involves regulation of select diacylglycerol kinases (DGKs). J Cell Biochem. 2005 Mar 01; 94(4):774-93. PMID: 15578578.
    Citations: 5     Fields:    Translation:HumansCells
  150. Fujita T, Zawawi KH, Kurihara H, Van Dyke TE. CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase. Cell Signal. 2005 Feb; 17(2):167-75. PMID: 15494208.
    Citations: 8     Fields:    Translation:HumansCells
  151. Van Dyke TE, Sheilesh D. Risk factors for periodontitis. J Int Acad Periodontol. 2005 Jan; 7(1):3-7. PMID: 15736889.
    Citations: 56     Fields:    Translation:Humans
  152. Van Dyke T, Litkowski LJ, Kiersch TA, Zarringhalam NM, Zheng H, Newman K. Combination oxycodone 5 mg/ibuprofen 400 mg for the treatment of postoperative pain: a double-blind, placebo- and active-controlled parallel-group study. Clin Ther. 2004 Dec; 26(12):2003-14. PMID: 15823764.
    Citations: 5     Fields:    Translation:HumansCTClinical Trials
  153. Bimstein E, Sapir S, Houri-Haddad Y, Dibart S, Van Dyke TE, Shapira L. The relationship between Porphyromonas gingivalis infection and local and systemic factors in children. J Periodontol. 2004 Oct; 75(10):1371-6. PMID: 15562915.
    Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
  154. Preshaw PM, Hefti AF, Novak MJ, Michalowicz BS, Pihlstrom BL, Schoor R, Trummel CL, Dean J, Van Dyke TE, Walker CB, Bradshaw MH. Subantimicrobial dose doxycycline enhances the efficacy of scaling and root planing in chronic periodontitis: a multicenter trial. J Periodontol. 2004 Aug; 75(8):1068-76. PMID: 15455733.
    Citations: 10     Fields:    Translation:HumansCTClinical Trials
  155. Ohira T, Bannenberg G, Arita M, Takahashi M, Ge Q, Van Dyke TE, Stahl GL, Serhan CN, Badwey JA. A stable aspirin-triggered lipoxin A4 analog blocks phosphorylation of leukocyte-specific protein 1 in human neutrophils. J Immunol. 2004 Aug 01; 173(3):2091-8. PMID: 15265945.
    Citations: 16     Fields:    Translation:HumansCells
  156. Dave S, Batista EL, Van Dyke TE. Cardiovascular disease and periodontal diseases: commonality and causation. Compend Contin Educ Dent. 2004 Jul; 25(7 Suppl 1):26-37. PMID: 15645884.
    Citations: 5     Fields:    Translation:HumansAnimals
  157. Froum S, Weinberg M, Novak J, Mailhot J, Mellonig J, Van Dyke T, McClain P, Papapanou PN, Childers G, Ciancio S, Blieden T, Polson A, Greenstein G, Yukna R, Wallace ML, Patters M, Wagener C. A multicenter study evaluating the sensitization potential of enamel matrix derivative after treatment of two infrabony defects. J Periodontol. 2004 Jul; 75(7):1001-8. PMID: 15341359.
    Citations: 2     Fields:    Translation:Humans
  158. Casavecchia P, Uzel MI, Kantarci A, Hasturk H, Dibart S, Hart TC, Trackman PC, Van Dyke TE. Hereditary gingival fibromatosis associated with generalized aggressive periodontitis: a case report. J Periodontol. 2004 May; 75(5):770-8. PMID: 15212361.
    Citations: 13     Fields:    Translation:Humans
  159. Dillon S, Agrawal A, Van Dyke T, Landreth G, McCauley L, Koh A, Maliszewski C, Akira S, Pulendran B. A Toll-like receptor 2 ligand stimulates Th2 responses in vivo, via induction of extracellular signal-regulated kinase mitogen-activated protein kinase and c-Fos in dendritic cells. J Immunol. 2004 Apr 15; 172(8):4733-43. PMID: 15067049.
    Citations: 144     Fields:    Translation:AnimalsCells
  160. Iontcheva I, Amar S, Zawawi KH, Kantarci A, Van Dyke TE. Role for moesin in lipopolysaccharide-stimulated signal transduction. Infect Immun. 2004 Apr; 72(4):2312-20. PMID: 15039356.
    Citations: 8     Fields:    Translation:HumansCells
  161. Donley CL, Badovinac R, Sapir S, Shapira L, Houri Y, Kantarci A, Warbington ML, Dibart S, Van Dyke TE, Needleman HL, Karimbux N, Bimstein E. IgG antibody levels to Porphyromonas gingivalis and clinical measures in children. J Periodontol. 2004 Feb; 75(2):221-8. PMID: 15068109.
    Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
  162. Gronert K, Kantarci A, Levy BD, Clish CB, Odparlik S, Hasturk H, Badwey JA, Colgan SP, Van Dyke TE, Serhan CN. A molecular defect in intracellular lipid signaling in human neutrophils in localized aggressive periodontal tissue damage. J Immunol. 2004 Feb 01; 172(3):1856-61. PMID: 14734770.
    Citations: 24     Fields:    Translation:HumansCells
  163. Fujita T, Shiba H, Van Dyke TE, Kurihara H. Differential effects of growth factors and cytokines on the synthesis of SPARC, DNA, fibronectin and alkaline phosphatase activity in human periodontal ligament cells. Cell Biol Int. 2004; 28(4):281-6. PMID: 15109984.
    Citations: 6     Fields:    Translation:HumansCells
  164. Hasturk H, Nunn M, Warbington M, Van Dyke TE. Efficacy of a fluoridated hydrogen peroxide-based mouthrinse for the treatment of gingivitis: a randomized clinical trial. J Periodontol. 2004 Jan; 75(1):57-65. PMID: 15025217.
    Citations: 4     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  165. Serhan CN, Jain A, Marleau S, Clish C, Kantarci A, Behbehani B, Colgan SP, Stahl GL, Merched A, Petasis NA, Chan L, Van Dyke TE. Reduced inflammation and tissue damage in transgenic rabbits overexpressing 15-lipoxygenase and endogenous anti-inflammatory lipid mediators. J Immunol. 2003 Dec 15; 171(12):6856-65. PMID: 14662892.
    Citations: 106     Fields:    Translation:HumansAnimalsCells
  166. Li Y, Xu L, Hasturk H, Kantarci A, DePalma SR, Van Dyke TE. Localized aggressive periodontitis is linked to human chromosome 1q25. Hum Genet. 2004 Feb; 114(3):291-7. PMID: 14673644.
    Citations: 10     Fields:    Translation:HumansCells
  167. Agrawal S, Agrawal A, Doughty B, Gerwitz A, Blenis J, Van Dyke T, Pulendran B. Cutting edge: different Toll-like receptor agonists instruct dendritic cells to induce distinct Th responses via differential modulation of extracellular signal-regulated kinase-mitogen-activated protein kinase and c-Fos. J Immunol. 2003 Nov 15; 171(10):4984-9. PMID: 14607893.
    Citations: 225     Fields:    Translation:HumansCells
  168. Oyaizu K, Kantarci A, Maeda H, Batista EL, Hasturk H, Murayama Y, Badwey JA, Van Dyke TE. Identification of mRNAs for the various diacylglycerol kinase isoforms in neutrophils from patients with localized aggressive periodontitis. J Periodontal Res. 2003 Oct; 38(5):488-95. PMID: 12941073.
    Citations:    Fields:    Translation:HumansCells
  169. Zhan Q, Ge Q, Ohira T, Van Dyke T, Badwey JA. p21-activated kinase 2 in neutrophils can be regulated by phosphorylation at multiple sites and by a variety of protein phosphatases. J Immunol. 2003 Oct 01; 171(7):3785-93. PMID: 14500679.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  170. Jain A, Batista EL, Serhan C, Stahl GL, Van Dyke TE. Role for periodontitis in the progression of lipid deposition in an animal model. Infect Immun. 2003 Oct; 71(10):6012-8. PMID: 14500522.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  171. Gyurko R, Boustany G, Huang PL, Kantarci A, Van Dyke TE, Genco CA, Gibson FC. Mice lacking inducible nitric oxide synthase demonstrate impaired killing of Porphyromonas gingivalis. Infect Immun. 2003 Sep; 71(9):4917-24. PMID: 12933833.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  172. Guzman S, Karima M, Wang HY, Van Dyke TE. Association between interleukin-1 genotype and periodontal disease in a diabetic population. J Periodontol. 2003 Aug; 74(8):1183-90. PMID: 14514232.
    Citations: 10     Fields:    Translation:Humans
  173. Dibart S, Capri D, Kachouh I, Van Dyke T, Nunn ME. Crown lengthening in mandibular molars: a 5-year retrospective radiographic analysis. J Periodontol. 2003 Jun; 74(6):815-21. PMID: 12886991.
    Citations: 5     Fields:    Translation:Humans
  174. Amar S, Gokce N, Morgan S, Loukideli M, Van Dyke TE, Vita JA. Periodontal disease is associated with brachial artery endothelial dysfunction and systemic inflammation. Arterioscler Thromb Vasc Biol. 2003 Jul 01; 23(7):1245-9. PMID: 12763762.
    Citations: 52     Fields:    Translation:Humans
  175. Buchmann R, Müller RF, Van Dyke TE, Lange DE. Change of antibiotic susceptibility following periodontal therapy. A pilot study in aggressive periodontal disease. J Clin Periodontol. 2003 Mar; 30(3):222-9. PMID: 12631180.
    Citations: 1     Fields:    Translation:HumansCells
  176. Delima AJ, Van Dyke TE. Origin and function of the cellular components in gingival crevice fluid. Periodontol 2000. 2003; 31:55-76. PMID: 12656996.
    Citations: 37     Fields:    Translation:HumansCells
  177. Kantarci A, Oyaizu K, Van Dyke TE. Neutrophil-mediated tissue injury in periodontal disease pathogenesis: findings from localized aggressive periodontitis. J Periodontol. 2003 Jan; 74(1):66-75. PMID: 12593599.
    Citations: 65     Fields:    Translation:HumansCells
  178. Kantarci A, Van Dyke TE. Lipoxins in chronic inflammation. Crit Rev Oral Biol Med. 2003; 14(1):4-12. PMID: 12764016.
    Citations: 17     Fields:    Translation:HumansAnimalsCells
  179. Kantarci A, Van Dyke TE. Neutrophil-mediated host response to Porphyromonas gingivalis. J Int Acad Periodontol. 2002 Oct; 4(4):119-25. PMID: 12670091.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  180. Buchmann R, Hasilik A, Van Dyke TE, Lange DE. Resolution of crevicular fluid leukocyte activity in patients treated for aggressive periodontal disease. J Periodontol. 2002 Sep; 73(9):995-1002. PMID: 12296600.
    Citations: 4     Fields:    Translation:HumansCells
  181. Catalanotto FA, Quissell D, Rekow D, Van Dyke TE. Local, regional, and global partnerships in developing a research program. J Dent Educ. 2002 Aug; 66(8):942-8; discussion 949-51. PMID: 12214842.
    Citations:    Fields:    Translation:Humans
  182. Newman HN, Van Dyke TE. The relationship between oral infections and systemic disease. J Int Acad Periodontol. 2002 Jul; 4(3):71. PMID: 12670084.
    Citations:    Fields:    Translation:Humans
  183. Oringer RJ, Van Dyke TE, Lessem J. The challenge of treating periodontal patients who smoke--the efficacy of Arestin. J Int Acad Periodontol. 2002 Jul; 4(3):89-94. PMID: 12670087.
    Citations:    Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  184. Van Dyke TE, Offenbacher S, Braswell L, Lessem J. Enhancing the value of scaling and root-planing: Arestin clinical trial results. J Int Acad Periodontol. 2002 Jul; 4(3):72-6. PMID: 12670085.
    Citations: 6     Fields:    Translation:HumansPHPublic HealthCTClinical Trials
  185. Buchmann R, Nunn ME, Van Dyke TE, Lange DE. Aggressive periodontitis: 5-year follow-up of treatment. J Periodontol. 2002 Jun; 73(6):675-83. PMID: 12083543.
    Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
  186. Buchmann R, Hasilik A, Nunn ME, Van Dyke TE, Lange DE. PMN responses in chronic periodontal disease: evaluation by gingival crevicular fluid enzymes and elastase-alpha-1-proteinase inhibitor complex. J Clin Periodontol. 2002 Jun; 29(6):563-72. PMID: 12296784.
    Citations: 7     Fields:    Translation:HumansCells
  187. Van Dyke TE. The oral/dental/craniofacial complex as a model for inflammatory disease. Compend Contin Educ Dent. 2002 May; 23(5):465-8, 470, 472 passim; quiz 476. PMID: 12060964.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  188. Van Dyke T, Paquette D, Grossi S, Braman V, Massaro J, D'Agostino R, Dibart S, Friden P. Clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis: a phase-2 multi-center study. J Clin Periodontol. 2002 Feb; 29(2):168-76. PMID: 11895545.
    Citations: 2     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
  189. Daniel MA, Van Dyke TE. Alterations in Phagocyte Function and Periodontal Infection. J Periodontol. 1996 Oct; 67 Suppl 10S:1070-1075. PMID: 29539788.
    Citations:    Fields:    
  190. Hart TC, Shapira L, Van Dyke TE. Neutrophil Defects as Risk Factors for Periodontal Diseases. J Periodontol. 1994 May; 65 Suppl 5S:521-529. PMID: 29539761.
    Citations:    Fields: