Harvard Catalyst Profiles

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Liron David, Ph.D.

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Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. David L, Martinez L, Xi Q, Kooshesh KA, Zhang Y, Shah JV, Maas RL, Wu H. Piezo mechanosensory channels regulate centrosome integrity and mitotic entry. Proc Natl Acad Sci U S A. 2023 01 03; 120(1):e2213846120. PMID: 36574677; PMCID: PMC9910506.
    Citations:    Fields:    Translation:Cells
  2. Xia M, David L, Teater M, Gutierrez J, Wang X, Meydan C, Lytle A, Slack GW, Scott DW, Morin RD, Onder O, Elenitoba-Johnson KSJ, Zamponi N, Cerchietti L, Lu T, Philippar U, Fontan L, Wu H, Melnick AM. BCL10 Mutations Define Distinct Dependencies Guiding Precision Therapy for DLBCL. Cancer Discov. 2022 08 05; 12(8):1922-1941. PMID: 35658124; PMCID: PMC9357155.
    Citations:    Fields:    Translation:HumansCells
  3. Andreeva L, David L, Rawson S, Shen C, Pasricha T, Pelegrin P, Wu H. NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation. Cell. 2021 12 22; 184(26):6299-6312.e22. PMID: 34861190; PMCID: PMC8763037.
    Citations: 30     Fields:    Translation:HumansAnimalsCells
  4. Robert Hollingsworth L, David L, Li Y, Griswold AR, Ruan J, Sharif H, Fontana P, Orth-He EL, Fu TM, Bachovchin DA, Wu H. Mechanism of filament formation in UPA-promoted CARD8 and NLRP1 inflammasomes. Nat Commun. 2021 01 08; 12(1):189. PMID: 33420033; PMCID: PMC7794386.
    Citations: 19     Fields:    Translation:HumansCells
  5. Hauseman ZJ, Harvey EP, Newman CE, Wales TE, Bucci JC, Mintseris J, Schweppe DK, David L, Fan L, Cohen DT, Herce HD, Mourtada R, Ben-Nun Y, Bloch NB, Hansen SB, Wu H, Gygi SP, Engen JR, Walensky LD. Homogeneous Oligomers of Pro-apoptotic BAX Reveal Structural Determinants of Mitochondrial Membrane Permeabilization. Mol Cell. 2020 07 02; 79(1):68-83.e7. PMID: 32533918.
    Citations: 12     Fields:    Translation:HumansAnimalsCells
  6. Stinson JR, Dorjbal B, McDaniel DP, David L, Wu H, Snow AL. Gain-of-function mutations in CARD11 promote enhanced aggregation and idiosyncratic signalosome assembly. Cell Immunol. 2020 07; 353:104129. PMID: 32473470.
    Citations: 4     Fields:    Translation:HumansCells
  7. David L, Li Y, Ma J, Garner E, Zhang X, Wu H. Assembly mechanism of the CARMA1-BCL10-MALT1-TRAF6 signalosome. Proc Natl Acad Sci U S A. 2018 02 13; 115(7):1499-1504. PMID: 29382759; PMCID: PMC5816215.
    Citations: 47     Fields:    Translation:HumansCells
  8. Zhang L, Chen S, Ruan J, Wu J, Tong AB, Yin Q, Li Y, David L, Lu A, Wang WL, Marks C, Ouyang Q, Zhang X, Mao Y, Wu H. Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization. Science. 2015 Oct 23; 350(6259):404-9. PMID: 26449474.
    Citations: 179     Fields:    Translation:AnimalsCells
  9. Yang C, David L, Qiao Q, Damko E, Wu H. The CBM signalosome: potential therapeutic target for aggressive lymphoma? Cytokine Growth Factor Rev. 2014 Apr; 25(2):175-83. PMID: 24411492.
    Citations: 7     Fields:    Translation:Cells
  10. Qiao Q, Yang C, Zheng C, Fontán L, David L, Yu X, Bracken C, Rosen M, Melnick A, Egelman EH, Wu H. Structural architecture of the CARMA1/Bcl10/MALT1 signalosome: nucleation-induced filamentous assembly. Mol Cell. 2013 Sep 26; 51(6):766-79. PMID: 24074955.
    Citations: 79     Fields:    Translation:HumansCells
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.