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Leo T. Chylack Jr., M.D.

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Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01EY012015 (CHYLACK, LEO T) Feb 1, 1998 - Jan 31, 2001
    NIH/NEI
    LENS EPITHELIAL CELL DERIVED GROWTH FACTOR
    Role: Principal Investigator
  2. R01EY005552 (CHYLACK, LEO T) Feb 1, 1985 - Jan 31, 1991
    NIH/NEI
    LENS METABOLISM AND CATARACT FORMATION
    Role: Principal Investigator
  3. M01RR002635 (GOTTLIEB, GARY L) Dec 1, 1984 - Mar 31, 2010
    NIH/NCRR
    General Clinical Research Center
    Role: Co-Principal Investigator
  4. R01EY003247 (CHYLACK, LEO T) Mar 1, 1984 - Feb 28, 1989
    NIH/NEI
    COOPERATIVE CATARACT RESEARCH CONSORTIUM
    Role: Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Weinstein SF, Andrews CP, Shah SR, Chylack LT, Tankelevich A, Ding Y, Tantry SK. Long-term efficacy and safety of once-daily treatment with beclomethasone dipropionate nasal aerosol. Allergy Asthma Proc. 2014 Jul-Aug; 35(4):323-31. PMID: 24992552.
    Citations: 1     Fields:    Translation:HumansCTClinical Trials
  2. Maspero J, Cherrez I, Doherty DE, Tashkin DP, Kuna P, Kuo WL, Gates D, Nolte H, Chylack LT. Appraisal of lens opacity with mometasone furoate/formoterol fumarate combination in patients with COPD or asthma. Respir Med. 2014 Sep; 108(9):1355-62. PMID: 25044280.
    Citations:    Fields:    Translation:Humans
  3. LaForce C, Journeay GE, Miller SD, Silvey MJ, Wu W, Lee LA, Chylack LT. Ocular safety of fluticasone furoate nasal spray in patients with perennial allergic rhinitis: a 2-year study. Ann Allergy Asthma Immunol. 2013 Jul; 111(1):45-50. PMID: 23806459.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  4. Chylack LT, Feiveson AH, Peterson LE, Tung WH, Wear ML, Marak LJ, Hardy DS, Chappell LJ, Cucinotta FA. NASCA report 2: Longitudinal study of relationship of exposure to space radiation and risk of lens opacity. Radiat Res. 2012 Jul; 178(1):25-32. PMID: 22687051.
    Citations: 7     Fields:    Translation:Humans
  5. Blakely EA, Kleiman NJ, Neriishi K, Chodick G, Chylack LT, Cucinotta FA, Minamoto A, Nakashima E, Kumagami T, Kitaoka T, Kanamoto T, Kiuchi Y, Chang P, Fujii N, Shore RE. Radiation cataractogenesis: epidemiology and biology. Radiat Res. 2010 May; 173(5):709-17. PMID: 20426671.
    Citations: 9     Fields:    Translation:Humans
  6. Chylack LT, Peterson LE, Feiveson AH, Wear ML, Manuel FK, Tung WH, Hardy DS, Marak LJ, Cucinotta FA. NASA study of cataract in astronauts (NASCA). Report 1: Cross-sectional study of the relationship of exposure to space radiation and risk of lens opacity. Radiat Res. 2009 Jul; 172(1):10-20. PMID: 19580503.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  7. Chylack LT, Gross GN, Pedinoff A. A randomized, controlled trial to investigate the effect of ciclesonide and beclomethasone dipropionate on eye lens opacity. J Asthma. 2008 Dec; 45(10):893-902. PMID: 19085579.
    Citations: 3     Fields:    Translation:Humans
  8. Song S, Hanson MJ, Liu BF, Chylack LT, Liang JJ. Protein-protein interactions between lens vimentin and alphaB-crystallin using FRET acceptor photobleaching. Mol Vis. 2008 Jul 10; 14:1282-7. PMID: 18618007.
    Citations: 16     Fields:    Translation:HumansCells
  9. Morris MS, Jacques PF, Chylack LT, Hankinson SE, Willett WC, Hubbard LD, Taylor A. Intake of zinc and antioxidant micronutrients and early age-related maculopathy lesions. Ophthalmic Epidemiol. 2007 Sep-Oct; 14(5):288-98. PMID: 17994438.
    Citations: 4     Fields:    Translation:Humans
  10. Lu M, Taylor A, Chylack LT, Rogers G, Hankinson SE, Willett WC, Jacques PF. Dietary linolenic acid intake is positively associated with five-year change in eye lens nuclear density. J Am Coll Nutr. 2007 Apr; 26(2):133-40. PMID: 17536124.
    Citations: 3     Fields:    Translation:Humans
  11. Herman DC, Gordon MO, Beiser JA, Chylack LT, Lamping KA, Schein OD, Soltau JB, Kass MA. Topical ocular hypotensive medication and lens opacification: evidence from the ocular hypertension treatment study. Am J Ophthalmol. 2006 Nov; 142(5):800-10. PMID: 17056362.
    Citations: 10     Fields:    Translation:Humans
  12. Chiu CJ, Hubbard LD, Armstrong J, Rogers G, Jacques PF, Chylack LT, Hankinson SE, Willett WC, Taylor A. Dietary glycemic index and carbohydrate in relation to early age-related macular degeneration. Am J Clin Nutr. 2006 Apr; 83(4):880-6. PMID: 16600942.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  13. Singh DP, Kubo E, Takamura Y, Shinohara T, Kumar A, Chylack LT, Fatma N. DNA binding domains and nuclear localization signal of LEDGF: contribution of two helix-turn-helix (HTH)-like domains and a stretch of 58 amino acids of the N-terminal to the trans-activation potential of LEDGF. J Mol Biol. 2006 Jan 20; 355(3):379-94. PMID: 16318853.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  14. Chang PY, Bjornstad KA, Rosen CJ, McNamara MP, Mancini R, Goldstein LE, Chylack LT, Blakely EA. Effects of iron ions, protons and X rays on human lens cell differentiation. Radiat Res. 2005 Oct; 164(4 Pt 2):531-9. PMID: 16187763.
    Citations: 9     Fields:    Translation:HumansCells
  15. Chiu CJ, Morris MS, Rogers G, Jacques PF, Chylack LT, Tung W, Hankinson SE, Willett WC, Taylor A. Carbohydrate intake and glycemic index in relation to the odds of early cortical and nuclear lens opacities. Am J Clin Nutr. 2005 Jun; 81(6):1411-6. PMID: 15941895.
    Citations: 11     Fields:    Translation:HumansPHPublic Health
  16. Jacques PF, Taylor A, Moeller S, Hankinson SE, Rogers G, Tung W, Ludovico J, Willett WC, Chylack LT. Long-term nutrient intake and 5-year change in nuclear lens opacities. Arch Ophthalmol. 2005 Apr; 123(4):517-26. PMID: 15824226.
    Citations: 9     Fields:    Translation:Humans
  17. Lu M, Taylor A, Chylack LT, Rogers G, Hankinson SE, Willett WC, Jacques PF. Dietary fat intake and early age-related lens opacities. Am J Clin Nutr. 2005 Apr; 81(4):773-9. PMID: 15817851.
    Citations: 10     Fields:    Translation:Humans
  18. Chylack LT, Fu L, Mancini R, Martin-Rehrmann MD, Saunders AJ, Konopka G, Tian D, Hedley-Whyte ET, Folkerth RD, Goldstein LE. Lens epithelium-derived growth factor (LEDGF/p75) expression in fetal and adult human brain. Exp Eye Res. 2004 Dec; 79(6):941-8. PMID: 15642333.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  19. Fatma N, Kubo E, Chylack LT, Shinohara T, Akagi Y, Singh DP. LEDGF regulation of alcohol and aldehyde dehydrogenases in lens epithelial cells: stimulation of retinoic acid production and protection from ethanol toxicity. Am J Physiol Cell Physiol. 2004 Aug; 287(2):C508-16. PMID: 15238362.
    Citations: 14     Fields:    Translation:AnimalsCells
  20. Moeller SM, Taylor A, Tucker KL, McCullough ML, Chylack LT, Hankinson SE, Willett WC, Jacques PF. Overall adherence to the dietary guidelines for americans is associated with reduced prevalence of early age-related nuclear lens opacities in women. J Nutr. 2004 Jul; 134(7):1812-9. PMID: 15226474.
    Citations: 12     Fields:    Translation:Humans
  21. Morris MS, Jacques PF, Hankinson SE, Chylack LT, Willett WC, Taylor A. Moderate alcoholic beverage intake and early nuclear and cortical lens opacities. Ophthalmic Epidemiol. 2004 Feb; 11(1):53-65. PMID: 14977497.
    Citations: 5     Fields:    Translation:Humans
  22. Jacques PF, Moeller SM, Hankinson SE, Chylack LT, Rogers G, Tung W, Wolfe JK, Willett WC, Taylor A. Weight status, abdominal adiposity, diabetes, and early age-related lens opacities. Am J Clin Nutr. 2003 Sep; 78(3):400-5. PMID: 12936921.
    Citations: 14     Fields:    Translation:Humans
  23. Goldstein LE, Muffat JA, Cherny RA, Moir RD, Ericsson MH, Huang X, Mavros C, Coccia JA, Faget KY, Fitch KA, Masters CL, Tanzi RE, Chylack LT, Bush AI. Cytosolic beta-amyloid deposition and supranuclear cataracts in lenses from people with Alzheimer's disease. Lancet. 2003 Apr 12; 361(9365):1258-65. PMID: 12699953.
    Citations: 80     Fields:    Translation:Humans
  24. Kubo E, Singh DP, Fatma N, Shinohara T, Zelenka P, Reddy VN, Chylack LT. Cellular distribution of lens epithelium-derived growth factor (LEDGF) in the rat eye: loss of LEDGF from nuclei of differentiating cells. Histochem Cell Biol. 2003 Apr; 119(4):289-99. PMID: 12692670.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  25. Sharma P, Fatma N, Kubo E, Shinohara T, Chylack LT, Singh DP. Lens epithelium-derived growth factor relieves transforming growth factor-beta1-induced transcription repression of heat shock proteins in human lens epithelial cells. J Biol Chem. 2003 May 30; 278(22):20037-46. PMID: 12649267.
    Citations: 18     Fields:    Translation:HumansCells
  26. Schalch W, Chylack LT. [Antioxidant micronutrients and cataract. Review and comparison of the AREDS and REACT cataract studies]. Ophthalmologe. 2003 Mar; 100(3):181-9. PMID: 12640546.
    Citations: 1     Fields:    Translation:HumansAnimals
  27. Davison JA, Chylack LT. Clinical application of the lens opacities classification system III in the performance of phacoemulsification. J Cataract Refract Surg. 2003 Jan; 29(1):138-45. PMID: 12551681.
    Citations: 13     Fields:    Translation:Humans
  28. Kubo E, Fatma N, Sharma P, Shinohara T, Chylack LT, Akagi Y, Singh DP. Transactivation of involucrin, a marker of differentiation in keratinocytes, by lens epithelium-derived growth factor (LEDGF). J Mol Biol. 2002 Jul 26; 320(5):1053-63. PMID: 12126624.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  29. Weintraub JM, Taylor A, Jacques P, Willett WC, Rosner B, Colditz GA, Chylack LT, Hankinson SE. Postmenopausal hormone use and lens opacities. Ophthalmic Epidemiol. 2002 Jul; 9(3):179-90. PMID: 12045885.
    Citations: 4     Fields:    Translation:Humans
  30. Thylefors B, Chylack LT, Konyama K, Sasaki K, Sperduto R, Taylor HR, West S. A simplified cataract grading system. Ophthalmic Epidemiol. 2002 Apr; 9(2):83-95. PMID: 11821974.
    Citations: 27     Fields:    Translation:Humans
  31. Taylor A, Jacques PF, Chylack LT, Hankinson SE, Khu PM, Rogers G, Friend J, Tung W, Wolfe JK, Padhye N, Willett WC. Long-term intake of vitamins and carotenoids and odds of early age-related cortical and posterior subcapsular lens opacities. Am J Clin Nutr. 2002 Mar; 75(3):540-9. PMID: 11864861.
    Citations: 20     Fields:    Translation:Humans
  32. Chylack LT, Brown NP, Bron A, Hurst M, Köpcke W, Thien U, Schalch W. The Roche European American Cataract Trial (REACT): a randomized clinical trial to investigate the efficacy of an oral antioxidant micronutrient mixture to slow progression of age-related cataract. Ophthalmic Epidemiol. 2002 Feb; 9(1):49-80. PMID: 11815895.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  33. Fatma N, Singh DP, Shinohara T, Chylack LT. Transcriptional regulation of the antioxidant protein 2 gene, a thiol-specific antioxidant, by lens epithelium-derived growth factor to protect cells from oxidative stress. J Biol Chem. 2001 Dec 28; 276(52):48899-907. PMID: 11677226.
    Citations: 44     Fields:    Translation:HumansAnimalsCells
  34. Nishizawa Y, Usukura J, Singh DP, Chylack LT, Shinohara T. Spatial and temporal dynamics of two alternatively spliced regulatory factors, lens epithelium-derived growth factor (ledgf/p75) and p52, in the nucleus. Cell Tissue Res. 2001 Jul; 305(1):107-14. PMID: 11512661.
    Citations: 23     Fields:    Translation:AnimalsCells
  35. Jacques PF, Chylack LT, Hankinson SE, Khu PM, Rogers G, Friend J, Tung W, Wolfe JK, Padhye N, Willett WC, Taylor A. Long-term nutrient intake and early age-related nuclear lens opacities. Arch Ophthalmol. 2001 Jul; 119(7):1009-19. PMID: 11448323.
    Citations: 27     Fields:    Translation:Humans
  36. Singh DP, Fatma N, Kimura A, Chylack LT, Shinohara T. LEDGF binds to heat shock and stress-related element to activate the expression of stress-related genes. Biochem Biophys Res Commun. 2001 May 18; 283(4):943-55. PMID: 11350077.
    Citations: 45     Fields:    Translation:Cells
  37. Machida S, Chaudhry P, Shinohara T, Singh DP, Reddy VN, Chylack LT, Sieving PA, Bush RA. Lens epithelium-derived growth factor promotes photoreceptor survival in light-damaged and RCS rats. Invest Ophthalmol Vis Sci. 2001 Apr; 42(5):1087-95. PMID: 11274090.
    Citations: 29     Fields:    Translation:AnimalsCellsPHPublic Health
  38. Sharma P, Singh DP, Fatma N, Chylack LT, Shinohara T. Activation of LEDGF gene by thermal-and oxidative-stresses. Biochem Biophys Res Commun. 2000 Oct 05; 276(3):1320-4. PMID: 11027629.
    Citations: 25     Fields:    Translation:AnimalsCells
  39. Fatma N, Singh DP, Shinohara T, Chylack LT. Heparin's roles in stabilizing, potentiating, and transporting LEDGF into the nucleus. Invest Ophthalmol Vis Sci. 2000 Aug; 41(9):2648-57. PMID: 10937578.
    Citations: 8     Fields:    Translation:AnimalsCells
  40. Goldstein LE, Leopold MC, Huang X, Atwood CS, Saunders AJ, Hartshorn M, Lim JT, Faget KY, Muffat JA, Scarpa RC, Chylack LT, Bowden EF, Tanzi RE, Bush AI. 3-Hydroxykynurenine and 3-hydroxyanthranilic acid generate hydrogen peroxide and promote alpha-crystallin cross-linking by metal ion reduction. Biochemistry. 2000 Jun 20; 39(24):7266-75. PMID: 10852726.
    Citations: 35     Fields:    Translation:HumansAnimalsCells
  41. Nakamura M, Singh DP, Kubo E, Chylack LT, Shinohara T. LEDGF: survival of embryonic chick retinal photoreceptor cells. Invest Ophthalmol Vis Sci. 2000 Apr; 41(5):1168-75. PMID: 10752956.
    Citations: 15     Fields:    Translation:AnimalsCells
  42. Shinohara T, Singh DP, Chylack LT. Review: Age-related cataract: immunity and lens epithelium-derived growth factor (LEDGF). J Ocul Pharmacol Ther. 2000 Apr; 16(2):181-91. PMID: 10803429.
    Citations: 11     Fields:    Translation:HumansAnimals
  43. Balaram M, Tung WH, Kuszak JR, Ayaki M, Shinohara T, Chylack LT. Noncontact specular microscopy of human lens epithelium. Invest Ophthalmol Vis Sci. 2000 Feb; 41(2):474-81. PMID: 10670478.
    Citations: 6     Fields:    Translation:HumansCells
  44. Singh DP, Kimura A, Chylack LT, Shinohara T. Lens epithelium-derived growth factor (LEDGF/p75) and p52 are derived from a single gene by alternative splicing. Gene. 2000 Jan 25; 242(1-2):265-73. PMID: 10721720.
    Citations: 31     Fields:    Translation:HumansAnimalsCells
  45. Singh DP, Ohguro N, Kikuchi T, Sueno T, Reddy VN, Yuge K, Chylack LT, Shinohara T. Lens epithelium-derived growth factor: effects on growth and survival of lens epithelial cells, keratinocytes, and fibroblasts. Biochem Biophys Res Commun. 2000 Jan 07; 267(1):373-81. PMID: 10623627.
    Citations: 34     Fields:    Translation:HumansAnimalsCells
  46. Siik S, Chylack LT, Friend J, Wolfe J, Teikari J, Nieminen H, Airaksinen PJ. Lens autofluorescence and light scatter in relation to the lens opacities classification system, LOCS III. Acta Ophthalmol Scand. 1999 Oct; 77(5):509-14. PMID: 10551289.
    Citations: 8     Fields:    Translation:Humans
  47. Ayaki M, Sueno T, Singh DP, Chylack LT, Shinohara T. Antibodies to lens epithelium-derived growth factor (LEDGF) kill epithelial cells of whole lenses in organ culture. Exp Eye Res. 1999 Jul; 69(1):139-42. PMID: 10375458.
    Citations: 2     Fields:    Translation:AnimalsCells
  48. Singh DP, Ohguro N, Chylack LT, Shinohara T. Lens epithelium-derived growth factor: increased resistance to thermal and oxidative stresses. Invest Ophthalmol Vis Sci. 1999 Jun; 40(7):1444-51. PMID: 10359326.
    Citations: 28     Fields:    Translation:AnimalsCells
  49. Lou MF, Dickerson JE, Tung WH, Wolfe JK, Chylack LT. Correlation of nuclear color and opalescence with protein S-thiolation in human lenses. Exp Eye Res. 1999 May; 68(5):547-52. PMID: 10328968.
    Citations: 13     Fields:    Translation:HumansCells
  50. Singh DP, Sueno T, Kikuchi T, Guru SC, Yu S, Horwitz J, Chylack LT, Shinohara T. Antibodies to a microbial peptide sharing sequence homology with betaA3-crystallin damage lens epithelial cells in vitro and in vivo. Autoimmunity. 1999; 29(4):311-22. PMID: 10433087.
    Citations:    Fields:    Translation:HumansAnimalsCellsPHPublic Health
  51. Das BK, Sun TX, Akhtar NJ, Chylack LT, Liang JJ. Fluorescence and immunochemical studies of advanced glycation-related lens pigments. Invest Ophthalmol Vis Sci. 1998 Oct; 39(11):2058-66. PMID: 9761284.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  52. Leske MC, Chylack LT, He Q, Wu SY, Schoenfeld E, Friend J, Wolfe J. Antioxidant vitamins and nuclear opacities: the longitudinal study of cataract. Ophthalmology. 1998 May; 105(5):831-6. PMID: 9593382.
    Citations: 19     Fields:    Translation:Humans
  53. Leske MC, Chylack LT, He Q, Wu SY, Schoenfeld E, Friend J, Wolfe J. Risk factors for nuclear opalescence in a longitudinal study. LSC Group. Longitudinal Study of Cataract. Am J Epidemiol. 1998 Jan 01; 147(1):36-41. PMID: 9440396.
    Citations: 14     Fields:    Translation:Humans
  54. Leske MC, Chylack LT, He Q, Wu SY, Schoenfeld E, Friend J, Wolfe J. Incidence and progression of cortical and posterior subcapsular opacities: the Longitudinal Study of Cataract. The LSC Group. Ophthalmology. 1997 Dec; 104(12):1987-93. PMID: 9400756.
    Citations: 10     Fields:    Translation:Humans
  55. Chylack LT. Cataracts and inhaled corticosteroids. N Engl J Med. 1997 Jul 03; 337(1):46-8. PMID: 9203433.
    Citations: 2     Fields:    Translation:Humans
  56. Ayaki M, Tung W, Wolfe JK, Shinohara T, Ibaraki N, Oharazawa H, Ohara K, Chylack LT. New non-contact specular microscope for lens epithelial cell visualization. Exp Eye Res. 1997 Jul; 65(1):143-6. PMID: 9237875.
    Citations:    Fields:    Translation:HumansAnimalsCells
  57. Chattopadhyay N, Ye C, Singh DP, Kifor O, Vassilev PM, Shinohara T, Chylack LT, Brown EM. Expression of extracellular calcium-sensing receptor by human lens epithelial cells. Biochem Biophys Res Commun. 1997 Apr 28; 233(3):801-5. PMID: 9168937.
    Citations: 9     Fields:    Translation:HumansCells
  58. Sueno T, Inoue E, Singh DP, Awata T, Chylack LT, Shinohara T. Oral administration of lens homogenate suppresses antibody production in mice injected with beta-crystallin emulsified in CFA. Exp Eye Res. 1997 Mar; 64(3):379-85. PMID: 9196389.
    Citations: 1     Fields:    Translation:AnimalsCells
  59. Ibaraki N, Lin LR, Dang L, Reddy VN, Singh DP, Sueno T, Chylack LT, Shinohara T. Anti-beta-crystallin antibodies (mouse) or sera from humans with age-related cataract are cytotoxic for lens epithelial cells in culture. Exp Eye Res. 1997 Feb; 64(2):229-38. PMID: 9176057.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  60. Leske MC, Chylack LT, Wu SY, Schoenfeld E, He Q, Friend J, Wolfe J. Incidence and progression of nuclear opacities in the Longitudinal Study of Cataract. Ophthalmology. 1996 May; 103(5):705-12. PMID: 8637678.
    Citations: 7     Fields:    Translation:Humans
  61. Leske MC, Wu SY, Hyman L, Sperduto R, Underwood B, Chylack LT, Milton RC, Srivastava S, Ansari N. Biochemical factors in the lens opacities. Case-control study. The Lens Opacities Case-Control Study Group. Arch Ophthalmol. 1995 Sep; 113(9):1113-9. PMID: 7661743.
    Citations: 13     Fields:    Translation:HumansCells
  62. Chylack LT, Wolfe JK, Friend J, Tung W, Singer DM, Brown NP, Hurst MA, Köpcke W, Schalch W. Validation of methods for the assessment of cataract progression in the Roche European-American Anticataract Trial (REACT) Ophthalmic Epidemiol. 1995 Jun; 2(2):59-75. PMID: 7585237.
    Citations: 8     Fields:    Translation:HumansCTClinical Trials
  63. Andley UP, Rhim JS, Chylack LT, Fleming TP. Propagation and immortalization of human lens epithelial cells in culture. Invest Ophthalmol Vis Sci. 1994 Jun; 35(7):3094-102. PMID: 8206728.
    Citations: 48     Fields:    Translation:HumansCells
  64. Kehoe R, Wu SY, Leske MC, Chylack LT. Comparing self-reported and physician-reported medical history. Am J Epidemiol. 1994 Apr 15; 139(8):813-8. PMID: 8178794.
    Citations: 106     Fields:    Translation:Humans
  65. Chylack LT, Mantell G, Wolfe JK, Friend J, Rosner B. Lovastatin and the human lens; results of a two year study. The MSDRL Study Group. Optom Vis Sci. 1993 Nov; 70(11):937-43. PMID: 8302530.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  66. Karbassi M, Khu PM, Singer DM, Chylack LT. Evaluation of lens opacities classification system III applied at the slitlamp. Optom Vis Sci. 1993 Nov; 70(11):923-8. PMID: 8302528.
    Citations: 14     Fields:    Translation:Humans
  67. Karbassi M, Magnante PC, Wolfe JK, Chylack LT. Objective line spread function measurements, Snellen acuity, and LOCS II classification in patients with cataract. Optom Vis Sci. 1993 Nov; 70(11):956-62. PMID: 8302532.
    Citations: 7     Fields:    Translation:Humans
  68. Chylack LT, Wolfe JK, Friend J, Khu PM, Singer DM, McCarthy D, del Carmen J, Rosner B. Quantitating cataract and nuclear brunescence, the Harvard and LOCS systems. Optom Vis Sci. 1993 Nov; 70(11):886-95. PMID: 8302524.
    Citations: 5     Fields:    Translation:Humans
  69. Chylack LT, Wolfe JK, Singer DM, Leske MC, Bullimore MA, Bailey IL, Friend J, McCarthy D, Wu SY. The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group. Arch Ophthalmol. 1993 Jun; 111(6):831-6. PMID: 8512486.
    Citations: 412     Fields:    Translation:Humans
  70. Chylack LT, Jakubicz G, Rosner B, Khu P, Libman J, Wolfe JK, Padhye N, Friend J. Contrast sensitivity and visual acuity in patients with early cataracts. J Cataract Refract Surg. 1993 May; 19(3):399-404. PMID: 8501637.
    Citations: 7     Fields:    Translation:Humans
  71. Chylack LT, Padhye N, Khu PM, Wehner C, Wolfe J, McCarthy D, Rosner B, Friend J. Loss of contrast sensitivity in diabetic patients with LOCS II classified cataracts. Br J Ophthalmol. 1993 Jan; 77(1):7-11. PMID: 8435406.
    Citations: 7     Fields:    Translation:Humans
  72. Seland JH, Chylack LT, Wolfe JK. Indirect spectral transmission ratio measurements of the aging crystalline lens nucleus. Acta Ophthalmol (Copenh). 1992 Jun; 70(3):376-82. PMID: 1636402.
    Citations:    Fields:    Translation:HumansCells
  73. Leske MC, Chylack LT, Wu SY. The Lens Opacities Case-Control Study. Risk factors for cataract. Arch Ophthalmol. 1991 Feb; 109(2):244-51. PMID: 1993036.
    Citations: 95     Fields:    Translation:HumansPHPublic Health
  74. Jacques PF, Chylack LT. Epidemiologic evidence of a role for the antioxidant vitamins and carotenoids in cataract prevention. Am J Clin Nutr. 1991 01; 53(1 Suppl):352S-355S. PMID: 1985409.
    Citations: 27     Fields:    Translation:HumansAnimals
  75. Andley UP, Chylack LT. Recent studies on photodamage to the eye with special reference to clinical phototherapeutic procedures. Photodermatol Photoimmunol Photomed. 1990 Jun; 7(3):98-105. PMID: 2081122.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  76. Chylack LT, Friend J. Intermediary metabolism of the lens: a historical perspective 1928-1989. Exp Eye Res. 1990 Jun; 50(6):575-82. PMID: 2197103.
    Citations:    Fields:    Translation:HumansAnimals
  77. Wolfe JK, Chylack LT. Objective measurement of cortical and subcapsular opacification in retroillumination photographs. Ophthalmic Res. 1990; 22 Suppl 1:62-7. PMID: 2388753.
    Citations: 1     Fields:    Translation:Humans
  78. Chylack LT, Leske MC, McCarthy D, Khu P, Kashiwagi T, Sperduto R. Lens opacities classification system II (LOCS II) Arch Ophthalmol. 1989 Jul; 107(7):991-7. PMID: 2751471.
    Citations: 97     Fields:    Translation:Humans
  79. Clair WK, Chylack LT, Cook EF, Goldman L. Allopurinol use and the risk of cataract formation. Br J Ophthalmol. 1989 Mar; 73(3):173-6. PMID: 2706206.
    Citations: 2     Fields:    Translation:Humans
  80. Fagerholm P, Chylack LT. Regional sensitivity to hypoglycemia within the rabbit lens epithelium. Acta Ophthalmol (Copenh). 1989 Feb; 67(1):13-20. PMID: 2773635.
    Citations:    Fields:    Translation:Animals
  81. Chylack LT, Leske MC, Khu P, McCarthy D, Wu SY. Strategies for measuring the rate of age-related cataract formation in vivo. Lens Eye Toxic Res. 1989; 6(4):515-22. PMID: 2487269.
    Citations: 1     Fields:    Translation:Humans
  82. Getty DJ, Pickett RM, Chylack LT, McCarthy DF, Huggins AW. An enriched set of features of nuclear cataract identified by multidimensional scaling. Curr Eye Res. 1989 Jan; 8(1):1-8. PMID: 2707035.
    Citations:    Fields:    Translation:Humans
  83. Harding CV, Unakar NJ, Bagchi M, Chylack LT, Jampel RS, Bobrowski WF, Dang L, Tsui JY, Harding D. Elemental and structural studies of the rat galactose cataract. Lens Eye Toxic Res. 1989; 6(3):477-501. PMID: 2486940.
    Citations:    Fields:    Translation:Animals
  84. Kodama T, Wolfe J, Chylack L, Smith J, Takemoto L. Quantitation of high molecular weight protein aggregates in opaque and transparent parts from the same human cataractous lens. Jpn J Ophthalmol. 1989; 33(1):114-9. PMID: 2733253.
    Citations:    Fields:    Translation:Humans
  85. Jacques PF, Hartz SC, Chylack LT, McGandy RB, Sadowski JA. Nutritional status in persons with and without senile cataract: blood vitamin and mineral levels. Am J Clin Nutr. 1988 Jul; 48(1):152-8. PMID: 3389322.
    Citations: 20     Fields:    Translation:Humans
  86. Cheng HM, González RG, von Saltza I, Chylack LT, Hutson NJ. Glucose flux and the redox state of pyridine dinucleotides in the rat lens. Exp Eye Res. 1988 Jun; 46(6):947-52. PMID: 3197763.
    Citations:    Fields:    Translation:Animals
  87. Chylack LT, Leske MC, Sperduto R, Khu P, McCarthy D. Lens Opacities Classification System. Arch Ophthalmol. 1988 Mar; 106(3):330-4. PMID: 3345149.
    Citations: 18     Fields:    Translation:Humans
  88. Jacques PF, Chylack LT, McGandy RB, Hartz SC. Antioxidant status in persons with and without senile cataract. Arch Ophthalmol. 1988 Mar; 106(3):337-40. PMID: 3345151.
    Citations: 21     Fields:    Translation:Humans
  89. Leske MC, Chylack LT, Sperduto R, Khu P, Wu SY, McCarthy D. Evaluation of a Lens Opacities Classification System. Arch Ophthalmol. 1988 Mar; 106(3):327-9. PMID: 3345148.
    Citations: 8     Fields:    Translation:Humans
  90. Chylack LT, Rosner B, White O, Tung WH, Sher LD. Standardization and analysis of digitized photographic data in the longitudinal documentation of cataractous growth. Curr Eye Res. 1988 Mar; 7(3):223-35. PMID: 3359808.
    Citations:    Fields:    Translation:HumansAnimals
  91. Tung WH, Chylack LT, Andley UP. Lens hexokinase deactivation by near-UV irradiation. Curr Eye Res. 1988 Mar; 7(3):257-63. PMID: 3359812.
    Citations: 4     Fields:    Translation:Animals
  92. Liang JN, Pelletier MR, Chylack LT. Front surface fluorometric study of lens insoluble proteins. Curr Eye Res. 1988 Jan; 7(1):61-7. PMID: 3359806.
    Citations: 1     Fields:    Translation:HumansAnimals
  93. Benedek GB, Chylack LT, Libondi T, Magnante P, Pennett M. Quantitative detection of the molecular changes associated with early cataractogenesis in the living human lens using quasielastic light scattering. Curr Eye Res. 1987 Dec; 6(12):1421-32. PMID: 3427992.
    Citations: 12     Fields:    Translation:Humans
  94. Chylack LT, Rosner B, Cheng HM, McCarthy D, Pennett M. Sources of variance in the objective documentation of human cataractous change with Topcon SL-45 and Neitz-CTR retroillumination photography and computerized image analysis. Curr Eye Res. 1987 Dec; 6(12):1381-90. PMID: 3427987.
    Citations: 1     Fields:    Translation:Humans
  95. Takemoto L, Kodama T, Wolfe J, Chylack L. Comparison of microdissected sections from the human cataractous lens by antisera to synthetic peptides. Invest Ophthalmol Vis Sci. 1987 Jul; 28(7):1210-3. PMID: 3596997.
    Citations:    Fields:    Translation:Humans
  96. Liang JN, Chylack LT. Spectroscopic study on the effects of nonenzymatic glycation in human alpha-crystallin. Invest Ophthalmol Vis Sci. 1987 May; 28(5):790-4. PMID: 3570690.
    Citations: 6     Fields:    Translation:HumansCells
  97. Latina M, Chylack LT, Fagerholm P, Nishio I, Tanaka T, Palmquist BM. Dynamic light scattering in the intact rabbit lens. Its relation to protein concentration. Invest Ophthalmol Vis Sci. 1987 Jan; 28(1):175-83. PMID: 3804648.
    Citations: 4     Fields:    Translation:Animals
  98. Leske MC, Chylack LT, Sperduto R, Pennett M, McCarthy D. Progress toward developing a cataract classification system. Dev Ophthalmol. 1987; 15:9-15. PMID: 3691929.
    Citations: 2     Fields:    Translation:Humans
  99. Bettelheim FA, Castoro JA, White O, Chylack LT. Topographic correspondence between total and non-freezable water content and the appearance of cataract in human lenses. Curr Eye Res. 1986 Dec; 5(12):925-32. PMID: 3802895.
    Citations: 3     Fields:    Translation:HumansCells
  100. Seland JH, Chylack LT. Acute glucose-derived osmotic stress in rabbit lenses. Acta Ophthalmol (Copenh). 1986 Oct; 64(5):533-9. PMID: 3811863.
    Citations: 2     Fields:    Translation:AnimalsCells
  101. Hoffman RW, Shaw S, Francis LC, Larson MG, Petersen RA, Chylack LT, Glass DN. HLA-DP antigens in patients with pauciarticular juvenile rheumatoid arthritis. Arthritis Rheum. 1986 Sep; 29(9):1057-62. PMID: 3489465.
    Citations: 11     Fields:    Translation:Humans
  102. Wolfe JK, Chylack LT. Glucose metabolism by human cataracts in culture. Exp Eye Res. 1986 Aug; 43(2):243-9. PMID: 3758223.
    Citations: 1     Fields:    Translation:Humans
  103. Libondi T, Magnante P, Chylack LT, Benedek GB. In vivo measurement of the aging rabbit lens using quasielastic light scattering. Curr Eye Res. 1986 Jun; 5(6):411-9. PMID: 3731821.
    Citations: 4     Fields:    Translation:Animals
  104. Kletzky DL, Tung WH, Chylack LT. The protective effect of glucose on soluble rat lens hexokinase in the presence of oxidative stress. Curr Eye Res. 1986 Jun; 5(6):433-9. PMID: 3015494.
    Citations:    Fields:    Translation:Animals
  105. Liang JN, Hershorin LL, Chylack LT. Non-enzymatic glycosylation in human diabetic lens crystallins. Diabetologia. 1986 Apr; 29(4):225-8. PMID: 3710014.
    Citations: 7     Fields:    Translation:HumansCells
  106. Barnett PA, González RG, Chylack LT, Cheng HM. The effect of oxidation on sorbitol pathway kinetics. Diabetes. 1986 Apr; 35(4):426-32. PMID: 3956880.
    Citations: 14     Fields:    Translation:HumansAnimalsCells
  107. Andley UP, Chylack LT. Change in sulfhydryl group microenvironment of calf lens alpha-crystallin by 300 nm light. Photochem Photobiol. 1986 Feb; 43(2):175-81. PMID: 3703956.
    Citations:    Fields:    Translation:Animals
  108. Chylack LT, Tung W, Harding R. Sorbitol production in the lens: a means of counteracting glucose-derived osmotic stress. Ophthalmic Res. 1986; 18(5):313-20. PMID: 3808597.
    Citations: 6     Fields:    Translation:Animals
  109. Bettelheim FA, Ali S, White O, Chylack LT. Freezable and non-freezable water content of cataractous human lenses. Invest Ophthalmol Vis Sci. 1986 Jan; 27(1):122-5. PMID: 3941033.
    Citations: 2     Fields:    Translation:HumansCells
  110. Chylack LT, Tung WH. Inexpensive stereoscopic CCRG camera for lens/cataract photography in vitro. Invest Ophthalmol Vis Sci. 1986 Jan; 27(1):118-22. PMID: 3941032.
    Citations:    Fields:    Translation:Humans
  111. Liang JN, Andley UP, Chylack LT. Spectroscopic studies on human lens crystallins. Biochim Biophys Acta. 1985 Nov 29; 832(2):197-203. PMID: 4063377.
    Citations: 7     Fields:    Translation:HumansCells
  112. Andley UP, Chapman SF, Chylack LT. Fluorescence studies on tryptophan and sulfhydryl group changes of bovine lens crystallins in a photodynamic system. Curr Eye Res. 1985 Aug; 4(8):831-42. PMID: 4042665.
    Citations: 2     Fields:    Translation:AnimalsCells
  113. Bettelheim FA, Chylack LT. Light scattering of whole excised human cataractous lenses. Relationships between different light scattering parameters. Exp Eye Res. 1985 Jul; 41(1):19-30. PMID: 4029284.
    Citations: 2     Fields:    Translation:Humans
  114. Wolfe JK, Gillis MK, Chylack LT. Glucose metabolism in the calf lens. Exp Eye Res. 1985 Apr; 40(4):629-41. PMID: 4007077.
    Citations:    Fields:    Translation:Animals
  115. Cheng HM, González RG, Barnett PA, Aguayo JB, Wolfe J, Chylack LT. Sorbitol/fructose metabolism in the lens. Exp Eye Res. 1985 Feb; 40(2):223-9. PMID: 3979463.
    Citations:    Fields:    Translation:Animals
  116. Chylack LT, Rosner B, Garner W, Giblin F, Waldron W, Wolfe J, Leske MC, White O. Validity and reproducibility of the Cooperative Cataract Research Group (CCRG) cataract classification system. Exp Eye Res. 1985 Jan; 40(1):135-47. PMID: 3979455.
    Citations: 1     Fields:    Translation:Humans
  117. Garlick RL, Mazer JS, Chylack LT, Tung WH, Bunn HF. Nonenzymatic glycation of human lens crystallin. Effect of aging and diabetes mellitus. J Clin Invest. 1984 Nov; 74(5):1742-9. PMID: 6438156.
    Citations: 19     Fields:    Translation:Humans
  118. González RG, Barnett P, Cheng HM, Chylack LT. Altered phosphate metabolism in the intact rabbit lens under high glucose conditions and its prevention by an aldose reductase inhibitor. Exp Eye Res. 1984 Nov; 39(5):553-62. PMID: 6440802.
    Citations:    Fields:    Translation:Animals
  119. Liang JN, Chylack LT. Change in the protein tertiary structure with non-enzymatic glycosylation of calf alpha-crystallin. Biochem Biophys Res Commun. 1984 Sep 28; 123(3):899-906. PMID: 6487332.
    Citations: 2     Fields:    Translation:AnimalsCells
  120. Chylack LT. Mechanisms of senile cataract formation. Ophthalmology. 1984 Jun; 91(6):596-602. PMID: 6431351.
    Citations: 7     Fields:    Translation:HumansCells
  121. Miller ML, Fraser PA, Jackson JM, Larson MG, Petersen RA, Chylack LT, Glass DN. Inherited predisposition to iridocyclitis with juvenile rheumatoid arthritis: selectivity among HLA-DR5 haplotypes. Proc Natl Acad Sci U S A. 1984 Jun; 81(11):3539-42. PMID: 6610178.
    Citations: 9     Fields:    Translation:Humans
  122. González RG, Barnett P, Aguayo J, Cheng HM, Chylack LT. Direct measurement of polyol pathway activity in the ocular lens. Diabetes. 1984 Feb; 33(2):196-9. PMID: 6692996.
    Citations: 23     Fields:    Translation:Animals
  123. Chylack LT, Ransil BJ, White O. Classification of human senile cataractous change by the American Cooperative Cataract Research Group (CCRG) method: III. The association of nuclear color (sclerosis) with extent of cataract formation, age, and visual acuity. Invest Ophthalmol Vis Sci. 1984 Feb; 25(2):174-80. PMID: 6698740.
    Citations: 9     Fields:    Translation:Humans
  124. Chylack LT, White O, Tung WH. Classification of human senile cataractous change by the American Cooperative Cataract Research Group (CCRG) method: II. Staged simplification of cataract classification. Invest Ophthalmol Vis Sci. 1984 Feb; 25(2):166-73. PMID: 6698739.
    Citations: 3     Fields:    Translation:Humans
  125. Chylack LT. Classification of human cataractous change by the American Cooperative Cataract Research Group method. Ciba Found Symp. 1984; 106:3-24. PMID: 6568979.
    Citations: 2     Fields:    Translation:Humans
  126. Harding CV, Chylack LT, Susan SR, Lo WK, Bobrowski WF. Calcium-containing opacities in the human lens. Invest Ophthalmol Vis Sci. 1983 Sep; 24(9):1194-202. PMID: 6885307.
    Citations: 3     Fields:    Translation:Humans
  127. Merriam JC, Chylack LT, Albert DM. Early-onset pauciarticular juvenile rheumatoid arthritis. A histopathologic study. Arch Ophthalmol. 1983 Jul; 101(7):1085-92. PMID: 6347150.
    Citations: 3     Fields:    Translation:Humans
  128. Cheng HM, Fagerholm P, Chylack LT. Response of the lens to oxidative-osmotic stress. Exp Eye Res. 1983 Jul; 37(1):11-21. PMID: 6873202.
    Citations: 3     Fields:    Translation:AnimalsCells
  129. Tanaka T, Rubin S, Sun ST, Nishio I, Tung WH, Chylack LT. Phase separation in rat lenses cultured in low glucose media. Invest Ophthalmol Vis Sci. 1983 Apr; 24(4):522-5. PMID: 6832923.
    Citations: 6     Fields:    Translation:AnimalsCells
  130. Bettelheim FA, Siew EL, Chylack LT, Seland JH. The effect of freezing on human cortical cataracts. Invest Ophthalmol Vis Sci. 1983 Apr; 24(4):403-8. PMID: 6832913.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  131. Chylack LT, Lee MR, Tung WH, Cheng HM. Classification of human senile cataractous changes by the American Cooperative Cataract Research Group (CCRG) method. I. Instrumentation and technique. Invest Ophthalmol Vis Sci. 1983 Apr; 24(4):424-31. PMID: 6832915.
    Citations: 8     Fields:    Translation:Humans
  132. Cheng HM, Chylack LT, Sang CN, Orzalesi N, Corongiu FP. GSSG-reducing activity in lenses deficient in glucose-6-phosphate dehydrogenase. Metab Pediatr Syst Ophthalmol. 1983; 7(1):53-7. PMID: 6621360.
    Citations: 1     Fields:    Translation:HumansAnimals
  133. Ryan EA, Zwaan J, Chylack LT. Nanophthalmos with uveal effusion: clinical and embryologic considerations. Ophthalmology. 1982 Sep; 89(9):1013-7. PMID: 7177566.
    Citations: 12     Fields:    Translation:Humans
  134. Gillis MK, Chylack LT. Depletion of sorbitol and fructose from young and older rat lenses. Exp Eye Res. 1982 Aug; 35(2):183-90. PMID: 7151885.
    Citations:    Fields:    Translation:Animals
  135. Harding CV, Chylack LT, Susan SR, Lo WK, Bobrowski WF. Elemental and ultrastructural analysis of specific human lens opacities. Invest Ophthalmol Vis Sci. 1982 Jul; 23(1):1-13. PMID: 7085211.
    Citations: 4     Fields:    Translation:HumansCells
  136. González RG, Willis J, Aguayo J, Campbell P, Chylack LT, Schleich T. 13C-nuclear magnetic resonance studies of sugar cataractogenesis in the single intact rabbit lens. Invest Ophthalmol Vis Sci. 1982 Jun; 22(6):808-11. PMID: 7076426.
    Citations: 1     Fields:    Translation:Animals
  137. Wolfe JK, Peczon BD, Chylack LT. Kinetics of calf lens phosphofructokinase activity at physiological substrate concentrations. Exp Eye Res. 1982 Jun; 34(6):945-52. PMID: 6282612.
    Citations:    Fields:    Translation:AnimalsCells
  138. Seland JH, Chylack LT. Cataracts in the exfoliation syndrome (fibrillopathia epitheliocapsularis). Trans Ophthalmol Soc U K. 1982; 102 Pt 3:375-9. PMID: 6964284.
    Citations: 3     Fields:    Translation:Humans
  139. Cheng HM, Chylack LT, von Saltza I. Supplementing glucose metabolism in human senile cataracts. Invest Ophthalmol Vis Sci. 1981 Dec; 21(6):812-8. PMID: 6458578.
    Citations: 2     Fields:    Translation:HumansAnimals
  140. Bellows AR, Chylack LT, Hutchinson BT. Choroidal detachment. Clinical manifestation, therapy and mechanism of formation. Ophthalmology. 1981 Nov; 88(11):1107-15. PMID: 7335316.
    Citations: 11     Fields:    Translation:Humans
  141. Chiou SH, Chylack LT, Tung WH, Bunn HF. Nonenzymatic glycosylation of bovine lens crystallins. Effect of aging. J Biol Chem. 1981 May 25; 256(10):5176-80. PMID: 7228874.
    Citations: 22     Fields:    Translation:AnimalsCells
  142. Wolfe JK, Peczon BD, Chylack LT. Calf lens phosphofructokinase: purification by single-step affinity chromatography and partial characterization. Exp Eye Res. 1981 May; 32(5):553-62. PMID: 6453718.
    Citations:    Fields:    Translation:Animals
  143. Gillis MK, Chylack LT, Cheng HM. Age and the control of glycolysis in the rat lens. Invest Ophthalmol Vis Sci. 1981 Apr; 20(4):457-66. PMID: 6452426.
    Citations: 1     Fields:    Translation:AnimalsCells
  144. Chylack LT, Bettelheim FA, Tung WH. Studies on human cataracts. I. Evaluation of techniques of human cataract preservation after extraction. Invest Ophthalmol Vis Sci. 1981 Mar; 20(3):327-33. PMID: 7203878.
    Citations: 3     Fields:    Translation:HumansCells
  145. Bettelheim FA, Siew EL, Chylack LT. Studies on human cataracts. III. Structural elements in nuclear cataracts and their contribution to the turbidity. Invest Ophthalmol Vis Sci. 1981 Mar; 20(3):348-54. PMID: 7203880.
    Citations: 5     Fields:    Translation:HumansCells
  146. Jedziniak JA, Chylack LT, Cheng HM, Gillis MK, Kalustian AA, Tung WH. The sorbitol pathway in the human lens: aldose reductase and polyol dehydrogenase. Invest Ophthalmol Vis Sci. 1981 Mar; 20(3):314-26. PMID: 6782033.
    Citations: 18     Fields:    Translation:HumansAnimals
  147. Siew EL, Bettelheim FA, Chylack LT, Tung WH. Studies on human cataracts. II. Correlation between the clinical description and the light-scattering parameters of human cataracts. Invest Ophthalmol Vis Sci. 1981 Mar; 20(3):334-47. PMID: 7203879.
    Citations: 2     Fields:    Translation:Humans
  148. Glass D, Litvin D, Wallace K, Chylack L, Garovoy M, Carpenter CB, Schur PH. Early-onset pauciarticular juvenile rheumatoid arthritis associated with human leukocyte antigen-DRw5, iritis, and antinuclear antibody. J Clin Invest. 1980 Sep; 66(3):426-9. PMID: 6967490.
    Citations: 18     Fields:    Translation:Humans
  149. Kador PF, Kinoshita JH, Tung WH, Chylack LT. Differences in the susceptibility of various aldose reductases to inhibition. II. Invest Ophthalmol Vis Sci. 1980 Aug; 19(8):980-2. PMID: 6773903.
    Citations: 5     Fields:    Translation:HumansAnimals
  150. Chiou SH, Chylack LT, Bunn HF, Kinoshita JH. Role of nonenzymatic glycosylation in experimental cataract formation. Biochem Biophys Res Commun. 1980 Jul 31; 95(2):894-901. PMID: 7417294.
    Citations: 7     Fields:    Translation:Animals
  151. Cheng HM, Chylack LT. Thiol oxidation in the crystalline lens. I. The rate-limiting role of hexokinase in aging rat and human lenses. Invest Ophthalmol Vis Sci. 1980 May; 19(5):522-8. PMID: 7372415.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  152. Parrish JA, Chylack LT, Woehler ME, Cheng HM, Pathak MA, Morison WL, Krugler J, Nelson WF. Dermatological and ocular examinations in rabbits chronically photosensitized with methoxsalen. J Invest Dermatol. 1979 Sep; 73(3):250-5. PMID: 469278.
    Citations: 5     Fields:    Translation:Animals
  153. Burns CL, Chylack LT. Thermal burns: the management of thermal burns of the lids and globes. Ann Ophthalmol. 1979 Sep; 11(9):1358-68. PMID: 400375.
    Citations: 2     Fields:    Translation:Humans
  154. Chylack LT, Henriques HF, Cheng HM, Tung WH. Efficacy of Alrestatin, an aldose reductase inhibitor, in human diabetic and nondiabetic lenses. Ophthalmology. 1979 Sep; 86(9):1579-85. PMID: 121768.
    Citations: 7     Fields:    Translation:Humans
  155. Bellows AR, Chylack LT, Epstein DL, Hutchinson BT. Choroidal effusion during glaucoma surgery in patients with prominent episcleral vessels. Arch Ophthalmol. 1979 Mar; 97(3):493-7. PMID: 420638.
    Citations: 11     Fields:    Translation:Humans
  156. Greiner JV, Chylack LT. Posterior subcapsular cataracts: histopathologic study of steroid-associated cataracts. Arch Ophthalmol. 1979 Jan; 97(1):135-44. PMID: 758890.
    Citations: 11     Fields:    Translation:HumansCells
  157. Chylack LT, Kinoshita JH. The Cooperative Cataract Research Group. Invest Ophthalmol Vis Sci. 1978 Dec; 17(12):1131-4. PMID: 721388.
    Citations: 1     Fields:    Translation:HumansAnimals
  158. Chylack LT, Cheng HM. Sugar metabolism in the crystalline lens. Surv Ophthalmol. 1978 Jul-Aug; 23(1):26-37. PMID: 100892.
    Citations: 2     Fields:    Translation:HumansAnimals
  159. Cheng HM, Chylack LT, Chien J. Control pyruvate kinase activity in the lens. Exp Eye Res. 1978 Jul; 27(1):39-44. PMID: 149672.
    Citations:    Fields:    Translation:HumansAnimalsCells
  160. Chylack LT. Classification of human cataracts. Arch Ophthalmol. 1978 May; 96(5):888-92. PMID: 655928.
    Citations: 6     Fields:    Translation:Humans
  161. Chylack LT, Bellows AR. Molecular sieving in suprachoroidal fluid formation in man. Invest Ophthalmol Vis Sci. 1978 May; 17(5):420-7. PMID: 640788.
    Citations: 1     Fields:    Translation:Humans
  162. Jedziniak JA, Baram H, Chylack LT. The molecular distribution, weight determination and concentration variation of the total water soluble proteins of the human lens. Exp Eye Res. 1978 Apr; 26(4):377-88. PMID: 639886.
    Citations: 1     Fields:    Translation:HumansAnimals
  163. Tanaka T, Ishimoto C, Chylack LT. Phase separation of a protein-water mixture in cold cataract in the young rat lens. Science. 1977 Sep 02; 197(4307):1010-2. PMID: 887936.
    Citations: 14     Fields:    Translation:Animals
  164. Calabro JJ, Chylack LT. Iridocyclisis associated with juvenile rheumatoid arthritis. Am J Ophthalmol. 1977 Aug; 84(2):274-5. PMID: 560799.
    Citations: 2     Fields:    Translation:Humans
  165. Cheng HM, Chylack LT. Regulation and stabilization of lens glucose-6-phosphate dehydrogenase. Exp Eye Res. 1977 May; 24(5):459-66. PMID: 16761.
    Citations:    Fields:    Translation:HumansAnimalsCells
  166. Chylack LT. The ocular manifestations of juvenile rheumatoid arthritis. Arthritis Rheum. 1977 Mar; 20(2 Suppl):217-23. PMID: 263899.
    Citations: 10     Fields:    Translation:Humans
  167. Cheng HM, Chylack LT, Chien J, Barañano EC. Stability of mammalian lens phosphofructokinase. Invest Ophthalmol Vis Sci. 1977 Feb; 16(2):126-34. PMID: 13048.
    Citations:    Fields:    Translation:HumansAnimalsCells
  168. Chylack LT, Schaefer FL. Mechanism of "hypoglycemic" cataract formation in the rat lens. II. Further studies on the role of hexokinase instability. Invest Ophthalmol. 1976 Jul; 15(7):519-28. PMID: 931698.
    Citations: 2     Fields:    Translation:AnimalsCells
  169. Cheng HM, Chylack LT. pH-dependent temperature sensitivity of rat lens phosphofructokinase. Invest Ophthalmol. 1976 Jun; 15(6):505-9. PMID: 6404.
    Citations:    Fields:    Translation:Animals
  170. Cheng HM, Chylack LT. Properties of rat lens phosphofructokinase. Invest Ophthalmol. 1976 Apr; 15(4):279-87. PMID: 4411.
    Citations:    Fields:    Translation:Animals
  171. Greiner JV, Chylack LT, Pihlaja DJ. Letter: Photomacrography of the crystalline normal and cataractous lens. Exp Eye Res. 1976 Mar; 22(3):281-4. PMID: 1269549.
    Citations:    Fields:    Translation:HumansAnimals
  172. Chylack LT. The characterization of the hexokinases in several tissues of the calf eye. Invest Ophthalmol. 1975 Nov; 14(11):854-62. PMID: 1184318.
    Citations: 1     Fields:    Translation:AnimalsCells
  173. Chylack LT. Mechanism of "hypoglycemic" cataract formation in the rat lens. I. The role of hexokinase instability. Invest Ophthalmol. 1975 Oct; 14(10):746-55. PMID: 1184308.
    Citations: 1     Fields:    Translation:Animals
  174. Spector R, Lightfoote JB, Cohen P, Chylack LT. Should tonometry screening be done by technicians instead of physicians? Arch Intern Med. 1975 Sep; 135(9):1260-2. PMID: 240334.
    Citations:    Fields:    Translation:HumansPHPublic Health
  175. Chylack LT, Bienfang DC, Bellows AR, Stillman JS. Ocular manifestations of juvenile rheumatoid arthritis. Am J Ophthalmol. 1975 Jun; 79(6):1026-33. PMID: 1079693.
    Citations: 14     Fields:    Translation:Humans
  176. Chylack LT. Thermo-instability of rat lens hexokinase. Exp Eye Res. 1973 Oct 24; 17(2):109-17. PMID: 4759528.
    Citations:    Fields:    Translation:AnimalsCells
  177. Chylack LT. Human lens hexokinase. Exp Eye Res. 1973 Feb; 15(2):225-33. PMID: 4632512.
    Citations:    Fields:    Translation:HumansAnimals
  178. Chylack LT, Kinoshita JH. The interaction of the lens and the vitreous. II. The influence of the vitreous on lens trauma, water and electrolyte balance and osmotic stress. Exp Eye Res. 1973 Jan 01; 15(1):61-9. PMID: 4683841.
    Citations: 2     Fields:    Translation:AnimalsCells
  179. Chylack LT, Kinoshita JH. The interaction of the lens and the vitreous. I. The high glucose cataract in a lens-vitreous preparation. Exp Eye Res. 1972 Jul; 14(1):58-64. PMID: 5039848.
    Citations: 2     Fields:    Translation:Animals
  180. Chylack LT. Sugar cataract. Arch Ophthalmol. 1972 May; 87(5):595. PMID: 5028100.
    Citations:    Fields:    Translation:Humans
  181. Chylack LT. Control of glycolysis in the lens. Exp Eye Res. 1971 May; 11(3):280-93. PMID: 4330780.
    Citations:    Fields:    Translation:HumansAnimalsCells
  182. Chylack LT, Kinoshita JH, Kasabian R. Nature and distribution of two distinct forms of hexokinase within the mammalian lens. Exp Eye Res. 1970 Oct; 10(2):250-62. PMID: 5484768.
    Citations: 1     Fields:    Translation:AnimalsCells
  183. Chylack LT, Kinoshita JH. A biochemical evaluation of a cataract induced in a high-glucose medium. Invest Ophthalmol. 1969 Aug; 8(4):401-12. PMID: 5796271.
    Citations: 18     Fields:    Translation:Animals
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.