I serve as the Director of Laboratory for Neuroimaging and Integrative Physiology within the Neural Systems Group in the Department of Psychiatry at Massachusetts Genera Hospital and Harvard Medical School.
I was trained as a translational neuroscientist and integrative physiologist with emphases in spaceflight/extreme physiology, neuroimaging, and neuromodulation. I am interested in human neurophysiologic and neurobehavioral performance in extreme operational environments, such as spaceflight and firefighting, development of countermeasures for mitigation of thus-induced medical conditions (e.g. spaceflight neurobehavioral decline and intracranial hypertension, post-traumatic stress disorder, traumatic brain injury, etc.), and their translation into clinical practice for treating analogous clinical conditions in the general population.
Within this research paradigm, I conducted numerous studies on healthy, elite (astronauts, firefighters, active military, athletes), and patient (Parkinson’s disease, cardiosurgical) populations in operational and clinical environments. My technical research expertise encompasses custom-developed ambulatory brain and multimodal physiology monitoring systems--NINscan--based on near-infrared spectroscopy (NIRS), as well as standard monitoring techniques including (f)MRI, 2D/3D/Doppler ultrasound, ophthalmic tonometry, biopotentials (ECG, EMG, EEG, EOG, EDA), actigraphy, and polysomnography.
I have developed curricula and taught extensively throughout my career both at the undergraduate and graduate levels, including courses in human systems physiology, spaceflight/extreme physiology, neurorehabilitation and biomechanics, and have mentored undergraduate and graduate students. .