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profileAlessio Fasano, M.D.

TitleProfessor of Pediatrics
InstitutionMassachusetts General Hospital
DepartmentPediatrics
AddressMassachusetts General Hospital
Cny
114 16th Street
Charlestown MA 02129
Phone617/724-4604
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
R01DK104344     (FASANO, ALESSIO)Jun 15, 2016 - May 31, 2021
NIH/NIDDK
Microbiome-derived Metabolites Linked to Celiac Disease Onset in Infants at Risk
Role: Principal Investigator

R34AT006945     (FASANO, ALESSIO)Sep 1, 2011 - Jun 30, 2014
NIH/NCCIH
Effect of Lactobacillus GG on gut permeability and microbiome in VLBW neonates
Role: Principal Investigator

U19AI090873     (KAPER, JAMES B)Jul 20, 2010 - Jun 30, 2015
NIH/NIAID
Severe Enteric Disease: Pathogenesis and Response
Role: Co-Principal Investigator

U19AI082655     (SZTEIN, MARCELO B.)Jun 18, 2009 - May 31, 2019
NIH/NIAID
Mucusal and Systemic Immunity, Vaccines and Microbiota Interplay in Humans
Role: Co-Principal Investigator

R21DK078699     (FASANO, ALESSIO)Apr 15, 2008 - Mar 31, 2011
NIH/NIDDK
Timing of Gluten Intake In Infant Nutrition and Risk of Celiac Disease Autoimmuni
Role: Principal Investigator

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Collapse selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Leonard MM, Cureton P, Fasano A. Indications and Use of the Gluten Contamination Elimination Diet for Patients with Non-Responsive Celiac Disease. Nutrients. 2017 Oct 18; 9(10). PMID: 29057833.
    View in: PubMed
  2. Leonard MM, Fasano A. Zero, One, or Two Endoscopies to Diagnose and Monitor Pediatric Celiac Disease? The Jury Is Still Out. J Pediatr Gastroenterol Nutr. 2017 Sep; 65(3):270-271. PMID: 28829342.
    View in: PubMed
  3. Booth JS, Patil SA, Ghazi L, Barnes R, Fraser CM, Fasano A, Greenwald BD, Sztein MB. Systemic and Terminal Ileum Mucosal Immunity Elicited by Oral Immunization With the Ty21a Typhoid Vaccine in Humans. Cell Mol Gastroenterol Hepatol. 2017 Nov; 4(3):419-437. PMID: 29022005.
    View in: PubMed
  4. Leonard MM, Sapone A, Catassi C, Fasano A. Celiac Disease and Nonceliac Gluten Sensitivity: A Review. JAMA. 2017 Aug 15; 318(7):647-656. PMID: 28810029.
    View in: PubMed
  5. Fasano A, Hill I. Serum Zonulin, Gut Permeability, and the Pathogenesis of Autism Spectrum Disorders: Cause, Effect, or an Epiphenomenon? J Pediatr. 2017 Sep; 188:15-17. PMID: 28624097.
    View in: PubMed
  6. Xian L, Georgess D, Huso T, Cope L, Belton A, Chang YT, Kuang W, Gu Q, Zhang X, Senger S, Fasano A, Huso DL, Ewald AJ, Resar LMS. HMGA1 amplifies Wnt signalling and expands the intestinal stem cell compartment and Paneth cell niche. Nat Commun. 2017 Apr 28; 8:15008. PMID: 28452345.
    View in: PubMed
  7. Sturgeon C, Lan J, Fasano A. Zonulin transgenic mice show altered gut permeability and increased morbidity/mortality in the DSS colitis model. Ann N Y Acad Sci. 2017 Jun; 1397(1):130-142. PMID: 28423466.
    View in: PubMed
  8. Fasano A. Celiac Disease, Gut-Brain Axis, and Behavior: Cause, Consequence, or Merely Epiphenomenon? Pediatrics. 2017 Mar; 139(3). PMID: 28219968.
    View in: PubMed
  9. Leonard MM, Weir DC, DeGroote M, Mitchell PD, Singh P, Silvester JA, Leichtner AM, Fasano A. Value of IgA tTG in Predicting Mucosal Recovery in Children With Celiac Disease on a Gluten-Free Diet. J Pediatr Gastroenterol Nutr. 2017 Feb; 64(2):286-291. PMID: 28112686.
    View in: PubMed
  10. Saleem B, Okogbule-Wonodi AC, Fasano A, Magder LS, Ravel J, Kapoor S, Viscardi RM. Intestinal Barrier Maturation in Very Low Birthweight Infants: Relationship to Feeding and Antibiotic Exposure. J Pediatr. 2017 Apr; 183:31-36.e1. PMID: 28159311.
    View in: PubMed
  11. Kang DW, Adams JB, Gregory AC, Borody T, Chittick L, Fasano A, Khoruts A, Geis E, Maldonado J, McDonough-Means S, Pollard EL, Roux S, Sadowsky MJ, Lipson KS, Sullivan MB, Caporaso JG, Krajmalnik-Brown R. Microbiota Transfer Therapy alters gut ecosystem and improves gastrointestinal and autism symptoms: an open-label study. Microbiome. 2017 Jan 23; 5(1):10. PMID: 28122648.
    View in: PubMed
  12. Serena G, Yan S, Camhi S, Patel S, Lima RS, Sapone A, Leonard MM, Mukherjee R, Nath BJ, Lammers KM, Fasano A. Proinflammatory cytokine interferon-? and microbiome-derived metabolites dictate epigenetic switch between forkhead box protein 3 isoforms in coeliac disease. Clin Exp Immunol. 2017 Mar; 187(3):490-506. PMID: 27936497.
    View in: PubMed
  13. Ciccia F, Guggino G, Rizzo A, Alessandro R, Luchetti MM, Milling S, Saieva L, Cypers H, Stampone T, Di Benedetto P, Gabrielli A, Fasano A, Elewaut D, Triolo G. Dysbiosis and zonulin upregulation alter gut epithelial and vascular barriers in patients with ankylosing spondylitis. Ann Rheum Dis. 2017 Jun; 76(6):1123-1132. PMID: 28069576.
    View in: PubMed
  14. Fasano A. Gut permeability, obesity, and metabolic disorders: who is the chicken and who is the egg? Am J Clin Nutr. 2017 Jan; 105(1):3-4. PMID: 28003208.
    View in: PubMed
  15. Greuter T, Schmidlin S, Lattmann J, Stotz M, Lehmann R, Zeitz J, Scharl M, Misselwitz B, Pohl D, Fried M, Tutuian R, Fasano A, Schoepfer AM, Rogler G, Biedermann L, Vavricka SR. The perspective of celiac disease patients on emerging treatment options and non-celiac gluten sensitivity. Dig Liver Dis. 2017 Mar; 49(3):268-272. PMID: 28034662.
    View in: PubMed
  16. Catassi C, Fasano A. Tempters and Gluten-Free Diet. Nutrients. 2016 Dec 03; 8(12). PMID: 27918479.
    View in: PubMed
  17. Fiorentino M, Sapone A, Senger S, Camhi SS, Kadzielski SM, Buie TM, Kelly DL, Cascella N, Fasano A. Blood-brain barrier and intestinal epithelial barrier alterations in autism spectrum disorders. Mol Autism. 2016; 7:49. PMID: 27957319.
    View in: PubMed
  18. Sturgeon C, Fasano A. Zonulin, a regulator of epithelial and endothelial barrier functions, and its involvement in chronic inflammatory diseases. Tissue Barriers. 2016; 4(4):e1251384. PMID: 28123927.
    View in: PubMed
  19. Guerrant RL, Leite AM, Pinkerton R, Medeiros PH, Cavalcante PA, DeBoer M, Kosek M, Duggan C, Gewirtz A, Kagan JC, Gauthier AE, Swann J, Mayneris-Perxachs J, Bolick DT, Maier EA, Guedes MM, Moore SR, Petri WA, Havt A, Lima IF, Prata MM, Michaleckyj JC, Scharf RJ, Sturgeon C, Fasano A, Lima AA. Biomarkers of Environmental Enteropathy, Inflammation, Stunting, and Impaired Growth in Children in Northeast Brazil. PLoS One. 2016; 11(9):e0158772. PMID: 27690129.
    View in: PubMed
  20. Faherty CS, Wu T, Morris CR, Grassel CL, Rasko DA, Harper JM, Shea-Donohue T, Fasano A, Barry EM. The synthesis of OspD3 (ShET2) in Shigella flexneri is independent of OspC1. Gut Microbes. 2016 Nov; 7(6):486-502. PMID: 27657187.
    View in: PubMed
  21. Vavricka SR, Stelzer T, Lattmann J, Stotz M, Lehmann R, Zeitz J, Scharl M, Misselwitz B, Pohl D, Fried M, Tutuian R, Fasano A, Schoepfer AM, Rogler G, Biedermann L, Greuter T. Celiac Disease is Misdiagnosed Based on Serology Only in a Substantial Proportion of Patients. J Clin Gastroenterol. 2016 Sep 15. PMID: 27636410.
    View in: PubMed
  22. Martin VJ, Leonard MM, Fiechtner L, Fasano A. Transitioning From Descriptive to Mechanistic Understanding of the Microbiome: The Need for a Prospective Longitudinal Approach to Predicting Disease. J Pediatr. 2016 Dec; 179:240-248. PMID: 27634626.
    View in: PubMed
  23. Delichatsios H, Fasano A. Case 14-2016: A Woman with a Thyroid Nodule and Psychosis. N Engl J Med. 2016 09 01; 375(9):e20. PMID: 27579661.
    View in: PubMed
  24. Snyder J, Butzner JD, DeFelice AR, Fasano A, Guandalini S, Liu E, Newton KP. Evidence-Informed Expert Recommendations for the Management of Celiac Disease in Children. Pediatrics. 2016 Sep; 138(3). PMID: 27565547.
    View in: PubMed
  25. Salerno-Goncalves R, Fasano A, Sztein MB. Development of a Multicellular Three-dimensional Organotypic Model of the Human Intestinal Mucosa Grown Under Microgravity. J Vis Exp. 2016 Jul 25; (113). PMID: 27500889; PMCID: PMC5032138 [Available on 07/25/17].
  26. Hill ID, Fasano A, Guandalini S, Hoffenberg E, Levy J, Reilly N, Verma R. NASPGHAN Clinical Report on the Diagnosis and Treatment of Gluten-related Disorders. J Pediatr Gastroenterol Nutr. 2016 Jul; 63(1):156-65. PMID: 27035374.
    View in: PubMed
  27. Vavricka SR, Vadasz N, Stotz M, Lehmann R, Studerus D, Greuter T, Frei P, Zeitz J, Scharl M, Misselwitz B, Pohl D, Fried M, Tutuian R, Fasano A, Schoepfer AM, Rogler G, Biedermann L. Celiac disease diagnosis still significantly delayed - Doctor's but not patients' delay responsive for the increased total delay in women. Dig Liver Dis. 2016 Oct; 48(10):1148-54. PMID: 27401607.
    View in: PubMed
  28. Lee J, Greenspan PT, Israel E, Katz A, Fasano A, Kaafarani HM, Linov PL, Raja AS, Rao SK. Emergency Department Utilization Report to Decrease Visits by Pediatric Gastroenterology Patients. Pediatrics. 2016 Jul; 138(1). PMID: 27287727.
    View in: PubMed
  29. Serena G, Leonard MM, Camhi S, Huedo-Medina TB, Fasano A. [Design of a genomic, environmental, microbial and metabolomic study on celiac disease: an approach to the future of personalized prevention of celiac disease]. Recenti Prog Med. 2016 Jun; 107(6):320-7. PMID: 27362724.
    View in: PubMed
  30. Shea-Donohue T, Fasano A, Zhao A, Notari L, Yan S, Sun R, Bohl JA, Desai N, Tudor G, Morimoto M, Booth C, Bennett A, Farese AM, MacVittie TJ. Mechanisms Involved in the Development of the Chronic Gastrointestinal Syndrome in Nonhuman Primates after Total-Body Irradiation with Bone Marrow Shielding. Radiat Res. 2016 Jun; 185(6):591-603. PMID: 27223826; PMCID: PMC4966619 [Available on 06/01/17].
  31. Delichatsios HK, Leonard MM, Fasano A, Nosé V. CASE RECORDS of the MASSACHUSETTS GENERAL HOSPITAL. Case 14-2016. A 37-Year-Old Woman with Adult-Onset Psychosis. N Engl J Med. 2016 May 12; 374(19):1875-83. PMID: 27168437.
    View in: PubMed
  32. Leonard MM, Fasano A. The microbiome as a possible target to prevent celiac disease. Expert Rev Gastroenterol Hepatol. 2016; 10(5):555-6. PMID: 26999627.
    View in: PubMed
  33. Fasano A. Gut microbiome and necrotising enterocolitis: time for intervention? Lancet. 2016 May 07; 387(10031):1884-5. PMID: 26969092.
    View in: PubMed
  34. Senger S, Sapone A, Fiorentino MR, Mazzarella G, Lauwers GY, Fasano A. Celiac Disease Histopathology Recapitulates Hedgehog Downregulation, Consistent with Wound Healing Processes Activation. PLoS One. 2015; 10(12):e0144634. PMID: 26649570; PMCID: PMC4674131.
  35. Leonard MM, Camhi S, Huedo-Medina TB, Fasano A. Celiac Disease Genomic, Environmental, Microbiome, and Metabolomic (CDGEMM) Study Design: Approach to the Future of Personalized Prevention of Celiac Disease. Nutrients. 2015 Nov 11; 7(11):9325-36. PMID: 26569299; PMCID: PMC4663598.
  36. Lammers KM, Chieppa M, Liu L, Liu S, Omatsu T, Janka-Junttila M, Casolaro V, Reinecker HC, Parent CA, Fasano A. Gliadin Induces Neutrophil Migration via Engagement of the Formyl Peptide Receptor, FPR1. PLoS One. 2015; 10(9):e0138338. PMID: 26378785; PMCID: PMC4574934.
  37. Serena G, Camhi S, Sturgeon C, Yan S, Fasano A. The Role of Gluten in Celiac Disease and Type 1 Diabetes. Nutrients. 2015 Aug 26; 7(9):7143-62. PMID: 26343710; PMCID: PMC4586524.
  38. Leffler DA, Green PH, Fasano A. Extraintestinal manifestations of coeliac disease. Nat Rev Gastroenterol Hepatol. 2015 Oct; 12(10):561-71. PMID: 26260366.
    View in: PubMed
  39. Lebwohl B, Murray JA, Verdú EF, Crowe SE, Dennis M, Fasano A, Green PH, Guandalini S, Khosla C. Gluten Introduction, Breastfeeding, and Celiac Disease: Back to the Drawing Board. Am J Gastroenterol. 2016 Jan; 111(1):12-4. PMID: 26259710; PMCID: PMC4720595.
  40. Catassi C, Elli L, Bonaz B, Bouma G, Carroccio A, Castillejo G, Cellier C, Cristofori F, de Magistris L, Dolinsek J, Dieterich W, Francavilla R, Hadjivassiliou M, Holtmeier W, Körner U, Leffler DA, Lundin KE, Mazzarella G, Mulder CJ, Pellegrini N, Rostami K, Sanders D, Skodje GI, Schuppan D, Ullrich R, Volta U, Williams M, Zevallos VF, Zopf Y, Fasano A. Diagnosis of Non-Celiac Gluten Sensitivity (NCGS): The Salerno Experts' Criteria. Nutrients. 2015 Jun 18; 7(6):4966-77. PMID: 26096570; PMCID: PMC4488826.
  41. Hollon J, Puppa EL, Greenwald B, Goldberg E, Guerrerio A, Fasano A. Effect of gliadin on permeability of intestinal biopsy explants from celiac disease patients and patients with non-celiac gluten sensitivity. Nutrients. 2015 Feb 27; 7(3):1565-76. PMID: 25734566; PMCID: PMC4377866.
  42. Rawal N, Twaddell W, Fasano A, Blanchard S, Safta A. Remission of Refractory Celiac Disease With Infliximab in a Pediatric Patient. ACG Case Rep J. 2015 Jan; 2(2):121-3. PMID: 26157934; PMCID: PMC4435386.
  43. Fasano A, Sapone A, Zevallos V, Schuppan D. Nonceliac gluten sensitivity. Gastroenterology. 2015 May; 148(6):1195-204. PMID: 25583468.
    View in: PubMed
  44. Lauwers GY, Fasano A, Brown IS. Duodenal lymphocytosis with no or minimal enteropathy: much ado about nothing? Mod Pathol. 2015 Jan; 28 Suppl 1:S22-9. PMID: 25560597.
    View in: PubMed
  45. Jackson J, Eaton W, Cascella N, Fasano A, Santora D, Sullivan K, Feldman S, Raley H, McMahon RP, Carpenter WT, Demyanovich H, Kelly DL. Gluten sensitivity and relationship to psychiatric symptoms in people with schizophrenia. Schizophr Res. 2014 Nov; 159(2-3):539-42. PMID: 25311778; PMCID: PMC4476307.
  46. Leonard MM, Serena G, Sturgeon C, Fasano A. Genetics and celiac disease: the importance of screening. Expert Rev Gastroenterol Hepatol. 2015 Feb; 9(2):209-15. PMID: 25294637.
    View in: PubMed
  47. Lionetti E, Castellaneta S, Francavilla R, Pulvirenti A, Tonutti E, Amarri S, Barbato M, Barbera C, Barera G, Bellantoni A, Castellano E, Guariso G, Limongelli MG, Pellegrino S, Polloni C, Ughi C, Zuin G, Fasano A, Catassi C. Introduction of gluten, HLA status, and the risk of celiac disease in children. N Engl J Med. 2014 Oct 02; 371(14):1295-303. PMID: 25271602.
    View in: PubMed
  48. Venkatesh M, Mukherjee S, Wang H, Li H, Sun K, Benechet AP, Qiu Z, Maher L, Redinbo MR, Phillips RS, Fleet JC, Kortagere S, Mukherjee P, Fasano A, Le Ven J, Nicholson JK, Dumas ME, Khanna KM, Mani S. Symbiotic bacterial metabolites regulate gastrointestinal barrier function via the xenobiotic sensor PXR and Toll-like receptor 4. Immunity. 2014 Aug 21; 41(2):296-310. PMID: 25065623; PMCID: PMC4142105.
  49. Catassi C, Fasano A. Coeliac disease. The debate on coeliac disease screening--are we there yet? Nat Rev Gastroenterol Hepatol. 2014 Aug; 11(8):457-8. PMID: 25001972.
    View in: PubMed
  50. Garner C, Ahn R, Ding YC, Steele L, Stoven S, Green PH, Fasano A, Murray JA, Neuhausen SL. Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus. PLoS One. 2014; 9(7):e101428. PMID: 24999842; PMCID: PMC4084811.
  51. Catassi C, Gatti S, Fasano A. The new epidemiology of celiac disease. J Pediatr Gastroenterol Nutr. 2014 Jul; 59 Suppl 1:S7-9. PMID: 24979197.
    View in: PubMed
  52. Shamir R, Heyman MB, Koning F, Wijmenga C, Wijimenga C, Gutierrez-Achury J, Catassi C, Gatti S, Fasano A, Discepolo V, Korponay-Szabó IR, Zevit N, Maki M, Schaart MW, Mearin ML, Troncone R. Celiac disease: past, present, and future challenges: dedicated to the memory of our friend and colleague, Prof David Branski (1944-2013). J Pediatr Gastroenterol Nutr. 2014 Jul; 59 Suppl 1:S1-20. PMID: 24840514.
    View in: PubMed
  53. Lakos G, Norman GL, Mahler M, Martis P, Bentow C, Santora D, Fasano A. Analytical and clinical comparison of two fully automated immunoassay systems for the diagnosis of celiac disease. J Immunol Res. 2014; 2014:371263. PMID: 24741592; PMCID: PMC3987800.
  54. Barada K, Habib RH, Malli A, Hashash JG, Halawi H, Maasri K, Tawil A, Mourad F, Sharara AI, Soweid A, Sukkarieh I, Chakhachiro Z, Jabbour M, Fasano A, Santora D, Arguelles C, Murray JA, Green PH. Prediction of celiac disease at endoscopy. Endoscopy. 2014 Feb; 46(2):110-9. PMID: 24477366.
    View in: PubMed
  55. Fiorentino M, Levine MM, Sztein MB, Fasano A. Effect of wild-type Shigella species and attenuated Shigella vaccine candidates on small intestinal barrier function, antigen trafficking, and cytokine release. PLoS One. 2014; 9(1):e85211. PMID: 24416363; PMCID: PMC3887025.
  56. Siniscalco D, Sapone A, Giordano C, Cirillo A, de Magistris L, Rossi F, Fasano A, Bradstreet JJ, Maione S, Antonucci N. Cannabinoid receptor type 2, but not type 1, is up-regulated in peripheral blood mononuclear cells of children affected by autistic disorders. J Autism Dev Disord. 2013 Nov; 43(11):2686-95. PMID: 23585028.
    View in: PubMed
  57. Catassi C, Bai JC, Bonaz B, Bouma G, Calabrò A, Carroccio A, Castillejo G, Ciacci C, Cristofori F, Dolinsek J, Francavilla R, Elli L, Green P, Holtmeier W, Koehler P, Koletzko S, Meinhold C, Sanders D, Schumann M, Schuppan D, Ullrich R, Vécsei A, Volta U, Zevallos V, Sapone A, Fasano A. Non-Celiac Gluten sensitivity: the new frontier of gluten related disorders. Nutrients. 2013 Sep 26; 5(10):3839-53. PMID: 24077239; PMCID: PMC3820047.
  58. de Magistris L, Picardi A, Siniscalco D, Riccio MP, Sapone A, Cariello R, Abbadessa S, Medici N, Lammers KM, Schiraldi C, Iardino P, Marotta R, Tolone C, Fasano A, Pascotto A, Bravaccio C. Antibodies against food antigens in patients with autistic spectrum disorders. Biomed Res Int. 2013; 2013:729349. PMID: 23984403; PMCID: PMC3747333.
  59. Vajro P, Paolella G, Fasano A. Microbiota and gut-liver axis: their influences on obesity and obesity-related liver disease. J Pediatr Gastroenterol Nutr. 2013 May; 56(5):461-8. PMID: 23287807; PMCID: PMC3637398.
  60. Alaish SM, Smith AD, Timmons J, Greenspon J, Eyvazzadeh D, Murphy E, Shea-Donahue T, Cirimotich S, Mongodin E, Zhao A, Fasano A, Nataro JP, Cross A. Gut microbiota, tight junction protein expression, intestinal resistance, bacterial translocation and mortality following cholestasis depend on the genetic background of the host. Gut Microbes. 2013 Jul-Aug; 4(4):292-305. PMID: 23652772; PMCID: PMC3744514.
  61. Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang MS, Grailer JJ, Zetoune FS, Andjelkovic AV, Fasano A, Ward PA. Zonulin as prehaptoglobin2 regulates lung permeability and activates the complement system. Am J Physiol Lung Cell Mol Physiol. 2013 Jun 15; 304(12):L863-72. PMID: 23564505; PMCID: PMC3680747.
  62. Hollon JR, Cureton PA, Martin ML, Puppa EL, Fasano A. Trace gluten contamination may play a role in mucosal and clinical recovery in a subgroup of diet-adherent non-responsive celiac disease patients. BMC Gastroenterol. 2013 Feb 28; 13:40. PMID: 23448408; PMCID: PMC3598839.
  63. Barry EM, Pasetti MF, Sztein MB, Fasano A, Kotloff KL, Levine MM. Progress and pitfalls in Shigella vaccine research. Nat Rev Gastroenterol Hepatol. 2013 Apr; 10(4):245-55. PMID: 23419287; PMCID: PMC3747556.
  64. Fiorentino M, Lammers KM, Levine MM, Sztein MB, Fasano A. In vitro Intestinal Mucosal Epithelial Responses to Wild-Type Salmonella Typhi and Attenuated Typhoid Vaccines. Front Immunol. 2013; 4:17. PMID: 23408152; PMCID: PMC3569575.
  65. Bai JC, Fried M, Corazza GR, Schuppan D, Farthing M, Catassi C, Greco L, Cohen H, Ciacci C, Eliakim R, Fasano A, González A, Krabshuis JH, LeMair A. World Gastroenterology Organisation global guidelines on celiac disease. J Clin Gastroenterol. 2013 Feb; 47(2):121-6. PMID: 23314668.
    View in: PubMed
  66. Fiorentino M, Ding H, Blanchard TG, Czinn SJ, Sztein MB, Fasano A. Helicobacter pylori-induced disruption of monolayer permeability and proinflammatory cytokine secretion in polarized human gastric epithelial cells. Infect Immun. 2013 Mar; 81(3):876-83. PMID: 23297384; PMCID: PMC3584868.
  67. Fasano A, Catassi C. Clinical practice. Celiac disease. N Engl J Med. 2012 Dec 20; 367(25):2419-26. PMID: 23252527.
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  68. Fabbri P, Calabrò AS, Hashimoto T, Fasano A, Caproni M. Novel advances in dermatitis herpetiformis. Clin Dev Immunol. 2012; 2012:450109. PMID: 23316253; PMCID: PMC3535881.
  69. Gibert A, Kruizinga AG, Neuhold S, Houben GF, Canela MA, Fasano A, Catassi C. Might gluten traces in wheat substitutes pose a risk in patients with celiac disease? A population-based probabilistic approach to risk estimation. Am J Clin Nutr. 2013 Jan; 97(1):109-16. PMID: 23193005.
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  70. Faherty CS, Faherty C, Harper JM, Shea-Donohue T, Barry EM, Kaper JB, Fasano A, Nataro JP. Chromosomal and plasmid-encoded factors of Shigella flexneri induce secretogenic activity ex vivo. PLoS One. 2012; 7(11):e49980. PMID: 23166804; PMCID: PMC3500342.
  71. Coury DL, Ashwood P, Fasano A, Fuchs G, Geraghty M, Kaul A, Mawe G, Patterson P, Jones NE. Gastrointestinal conditions in children with autism spectrum disorder: developing a research agenda. Pediatrics. 2012 Nov; 130 Suppl 2:S160-8. PMID: 23118247.
    View in: PubMed
  72. Fasano A. Novel therapeutic/integrative approaches for celiac disease and dermatitis herpetiformis. Clin Dev Immunol. 2012; 2012:959061. PMID: 23093980; PMCID: PMC3474991.
  73. Vanuytsel T, Senger S, Fasano A, Shea-Donohue T. Major signaling pathways in intestinal stem cells. Biochim Biophys Acta. 2013 Feb; 1830(2):2410-26. PMID: 22922290; PMCID: PMC4408610.
  74. Fasano A. Intestinal permeability and its regulation by zonulin: diagnostic and therapeutic implications. Clin Gastroenterol Hepatol. 2012 Oct; 10(10):1096-100. PMID: 22902773; PMCID: PMC3458511.
  75. Reilly NR, Fasano A, Green PH. Presentation of celiac disease. Gastrointest Endosc Clin N Am. 2012 Oct; 22(4):613-21. PMID: 23083982.
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  76. Jackson J, Eaton W, Cascella N, Fasano A, Warfel D, Feldman S, Richardson C, Vyas G, Linthicum J, Santora D, Warren KR, Carpenter WT, Kelly DL. A gluten-free diet in people with schizophrenia and anti-tissue transglutaminase or anti-gliadin antibodies. Schizophr Res. 2012 Sep; 140(1-3):262-3. PMID: 22771303; PMCID: PMC3641835.
  77. Siniscalco D, Sapone A, Giordano C, Cirillo A, de Novellis V, de Magistris L, Rossi F, Fasano A, Maione S, Antonucci N. The expression of caspases is enhanced in peripheral blood mononuclear cells of autism spectrum disorder patients. J Autism Dev Disord. 2012 Jul; 42(7):1403-10. PMID: 21969075.
    View in: PubMed
  78. Fasano A. Zonulin, regulation of tight junctions, and autoimmune diseases. Ann N Y Acad Sci. 2012 Jul; 1258:25-33. PMID: 22731712; PMCID: PMC3384703.
  79. Lionetti E, Castellaneta S, Pulvirenti A, Tonutti E, Francavilla R, Fasano A, Catassi C. Prevalence and natural history of potential celiac disease in at-family-risk infants prospectively investigated from birth. J Pediatr. 2012 Nov; 161(5):908-14. PMID: 22704250.
    View in: PubMed
  80. Ahn R, Ding YC, Murray J, Fasano A, Green PH, Neuhausen SL, Garner C. Association analysis of the extended MHC region in celiac disease implicates multiple independent susceptibility loci. PLoS One. 2012; 7(5):e36926. PMID: 22615847; PMCID: PMC3355177.
  81. Ludvigsson JF, Fasano A. Timing of introduction of gluten and celiac disease risk. Ann Nutr Metab. 2012; 60 Suppl 2:22-9. PMID: 22555186.
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  82. Cascella NG, Santora D, Gregory P, Kelly DL, Fasano A, Eaton WW. Increased prevalence of transglutaminase 6 antibodies in sera from schizophrenia patients. Schizophr Bull. 2013 Jul; 39(4):867-71. PMID: 22516148; PMCID: PMC3686447.
  83. Rossi F, Bellini G, Tolone C, Luongo L, Mancusi S, Papparella A, Sturgeon C, Fasano A, Nobili B, Perrone L, Maione S, del Giudice EM. The cannabinoid receptor type 2 Q63R variant increases the risk of celiac disease: implication for a novel molecular biomarker and future therapeutic intervention. Pharmacol Res. 2012 Jul; 66(1):88-94. PMID: 22465144.
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  84. Sellitto M, Bai G, Serena G, Fricke WF, Sturgeon C, Gajer P, White JR, Koenig SS, Sakamoto J, Boothe D, Gicquelais R, Kryszak D, Puppa E, Catassi C, Ravel J, Fasano A. Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants. PLoS One. 2012; 7(3):e33387. PMID: 22432018; PMCID: PMC3303818.
  85. Jackson JR, Eaton WW, Cascella NG, Fasano A, Kelly DL. Neurologic and psychiatric manifestations of celiac disease and gluten sensitivity. Psychiatr Q. 2012 Mar; 83(1):91-102. PMID: 21877216; PMCID: PMC3641836.
  86. Ludvigsson JF, Leffler DA, Bai JC, Biagi F, Fasano A, Green PH, Hadjivassiliou M, Kaukinen K, Kelly CP, Leonard JN, Lundin KE, Murray JA, Sanders DS, Walker MM, Zingone F, Ciacci C. The Oslo definitions for coeliac disease and related terms. Gut. 2013 Jan; 62(1):43-52. PMID: 22345659; PMCID: PMC3440559.
  87. Sapone A, Bai JC, Ciacci C, Dolinsek J, Green PH, Hadjivassiliou M, Kaukinen K, Rostami K, Sanders DS, Schumann M, Ullrich R, Villalta D, Volta U, Catassi C, Fasano A. Spectrum of gluten-related disorders: consensus on new nomenclature and classification. BMC Med. 2012 Feb 07; 10:13. PMID: 22313950; PMCID: PMC3292448.
  88. Fasano A. Leaky gut and autoimmune diseases. Clin Rev Allergy Immunol. 2012 Feb; 42(1):71-8. PMID: 22109896.
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  89. Netzel-Arnett S, Buzza MS, Shea-Donohue T, Désilets A, Leduc R, Fasano A, Bugge TH, Antalis TM. Matriptase protects against experimental colitis and promotes intestinal barrier recovery. Inflamm Bowel Dis. 2012 Jul; 18(7):1303-14. PMID: 22081509; PMCID: PMC3288858.
  90. Fasano A, Catassi C. Early feeding practices and their impact on development of celiac disease. Nestle Nutr Workshop Ser Pediatr Program. 2011; 68:201-9; discussion 210-3. PMID: 22044901.
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  91. Silva MA, Jury J, Sanz Y, Wiepjes M, Huang X, Murray JA, David CS, Fasano A, Verdú EF. Increased bacterial translocation in gluten-sensitive mice is independent of small intestinal paracellular permeability defect. Dig Dis Sci. 2012 Jan; 57(1):38-47. PMID: 21822909; PMCID: PMC3507358.
  92. Salerno-Goncalves R, Fasano A, Sztein MB. Engineering of a multicellular organotypic model of the human intestinal mucosa. Gastroenterology. 2011 Aug; 141(2):e18-20. PMID: 21723866; PMCID: PMC3328095.
  93. Sapone A, Lammers KM, Casolaro V, Cammarota M, Giuliano MT, De Rosa M, Stefanile R, Mazzarella G, Tolone C, Russo MI, Esposito P, Ferraraccio F, Cartenì M, Riegler G, de Magistris L, Fasano A. Divergence of gut permeability and mucosal immune gene expression in two gluten-associated conditions: celiac disease and gluten sensitivity. BMC Med. 2011 Mar 09; 9:23. PMID: 21392369; PMCID: PMC3065425.
  94. Fasano A. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiol Rev. 2011 Jan; 91(1):151-75. PMID: 21248165.
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  95. Lammers KM, Khandelwal S, Chaudhry F, Kryszak D, Puppa EL, Casolaro V, Fasano A. Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease. Immunology. 2011 Mar; 132(3):432-40. PMID: 21091908; PMCID: PMC3044909.
  96. Catassi C, Kryszak D, Bhatti B, Sturgeon C, Helzlsouer K, Clipp SL, Gelfond D, Puppa E, Sferruzza A, Fasano A. Natural history of celiac disease autoimmunity in a USA cohort followed since 1974. Ann Med. 2010 Oct; 42(7):530-8. PMID: 20868314.
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  97. Goldblum SE, Rai U, Tripathi A, Thakar M, De Leo L, Di Toro N, Not T, Ramachandran R, Puche AC, Hollenberg MD, Fasano A. The active Zot domain (aa 288-293) increases ZO-1 and myosin 1C serine/threonine phosphorylation, alters interaction between ZO-1 and its binding partners, and induces tight junction disassembly through proteinase activated receptor 2 activation. FASEB J. 2011 Jan; 25(1):144-58. PMID: 20852064; PMCID: PMC3005425.
  98. Catassi C, Fasano A. Celiac disease diagnosis: simple rules are better than complicated algorithms. Am J Med. 2010 Aug; 123(8):691-3. PMID: 20670718.
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  99. Shea-Donohue T, Fasano A, Smith A, Zhao A. Enteric pathogens and gut function: Role of cytokines and STATs. Gut Microbes. 2010 Sep; 1(5):316-324. PMID: 21327040.
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  100. Fasano A, Counts D. Commentary on "anti-pituitary antibodies in children with newly diagnosed celiac disease: a novel finding contributing to linear growth". Am J Gastroenterol. 2010 Mar; 105(3):697-8. PMID: 20203647.
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  101. Harris KM, Fasano A, Mann DL. Monocytes differentiated with IL-15 support Th17 and Th1 responses to wheat gliadin: implications for celiac disease. Clin Immunol. 2010 Jun; 135(3):430-9. PMID: 20153259; PMCID: PMC2868103.
  102. Buzza MS, Netzel-Arnett S, Shea-Donohue T, Zhao A, Lin CY, List K, Szabo R, Fasano A, Bugge TH, Antalis TM. Membrane-anchored serine protease matriptase regulates epithelial barrier formation and permeability in the intestine. Proc Natl Acad Sci U S A. 2010 Mar 02; 107(9):4200-5. PMID: 20142489; PMCID: PMC2840089.
  103. Sapone A, Lammers KM, Mazzarella G, Mikhailenko I, Cartenì M, Casolaro V, Fasano A. Differential mucosal IL-17 expression in two gliadin-induced disorders: gluten sensitivity and the autoimmune enteropathy celiac disease. Int Arch Allergy Immunol. 2010; 152(1):75-80. PMID: 19940509; PMCID: PMC2956008.
  104. Zawahir S, Safta A, Fasano A. Pediatric celiac disease. Curr Opin Pediatr. 2009 Oct; 21(5):655-60. PMID: 19606042.
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  105. Fasano A. Should we screen for coeliac disease? Yes. BMJ. 2009 Sep 17; 339:b3592. PMID: 19762413.
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  106. Tripathi A, Lammers KM, Goldblum S, Shea-Donohue T, Netzel-Arnett S, Buzza MS, Antalis TM, Vogel SN, Zhao A, Yang S, Arrietta MC, Meddings JB, Fasano A. Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2. Proc Natl Acad Sci U S A. 2009 Sep 29; 106(39):16799-804. PMID: 19805376; PMCID: PMC2744629.
  107. Fasano A. Surprises from celiac disease. Sci Am. 2009 Aug; 301(2):54-61. PMID: 19634568.
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  108. Lu R, Fasano S, Madayiputhiya N, Morin NP, Nataro J, Fasano A. Isolation, identification, and characterization of small bioactive peptides from Lactobacillus GG conditional media that exert both anti-Gram-negative and Gram-positive bactericidal activity. J Pediatr Gastroenterol Nutr. 2009 Jul; 49(1):23-30. PMID: 19465870.
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  109. Cascella NG, Kryszak D, Bhatti B, Gregory P, Kelly DL, Mc Evoy JP, Fasano A, Eaton WW. Prevalence of celiac disease and gluten sensitivity in the United States clinical antipsychotic trials of intervention effectiveness study population. Schizophr Bull. 2011 Jan; 37(1):94-100. PMID: 19494248; PMCID: PMC3004201.
  110. Visser J, Rozing J, Sapone A, Lammers K, Fasano A. Tight junctions, intestinal permeability, and autoimmunity: celiac disease and type 1 diabetes paradigms. Ann N Y Acad Sci. 2009 May; 1165:195-205. PMID: 19538307; PMCID: PMC2886850.
  111. Catassi C, Fasano A. Celiac disease. Curr Opin Gastroenterol. 2008 Nov; 24(6):687-91. PMID: 19122516.
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  112. Fasano A. Physiological, pathological, and therapeutic implications of zonulin-mediated intestinal barrier modulation: living life on the edge of the wall. Am J Pathol. 2008 Nov; 173(5):1243-52. PMID: 18832585; PMCID: PMC2570116.
  113. Catassi C, Fasano A. Is this really celiac disease? Pitfalls in diagnosis. Curr Gastroenterol Rep. 2008 Oct; 10(5):466-72. PMID: 18799121.
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  114. Harris KM, Fasano A, Mann DL. Cutting edge: IL-1 controls the IL-23 response induced by gliadin, the etiologic agent in celiac disease. J Immunol. 2008 Oct 01; 181(7):4457-60. PMID: 18802048.
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  115. Rallabhandi P, Nhu QM, Toshchakov VY, Piao W, Medvedev AE, Hollenberg MD, Fasano A, Vogel SN. Analysis of proteinase-activated receptor 2 and TLR4 signal transduction: a novel paradigm for receptor cooperativity. J Biol Chem. 2008 Sep 05; 283(36):24314-25. PMID: 18622013; PMCID: PMC2528983.
  116. Lammers KM, Lu R, Brownley J, Lu B, Gerard C, Thomas K, Rallabhandi P, Shea-Donohue T, Tamiz A, Alkan S, Netzel-Arnett S, Antalis T, Vogel SN, Fasano A. Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology. 2008 Jul; 135(1):194-204.e3. PMID: 18485912; PMCID: PMC2653457.
  117. Song KH, Fasano A, Eddington ND. Enhanced nasal absorption of hydrophilic markers after dosing with AT1002, a tight junction modulator. Eur J Pharm Biopharm. 2008 May; 69(1):231-7. PMID: 18039562.
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  118. Song KH, Fasano A, Eddington ND. Effect of the six-mer synthetic peptide (AT1002) fragment of zonula occludens toxin on the intestinal absorption of cyclosporin A. Int J Pharm. 2008 Mar 03; 351(1-2):8-14. PMID: 17954018.
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  119. Antalis TM, Shea-Donohue T, Vogel SN, Sears C, Fasano A. Mechanisms of disease: protease functions in intestinal mucosal pathobiology. Nat Clin Pract Gastroenterol Hepatol. 2007 Jul; 4(7):393-402. PMID: 17607295; PMCID: PMC3049113.
  120. Catassi C, Kryszak D, Louis-Jacques O, Duerksen DR, Hill I, Crowe SE, Brown AR, Procaccini NJ, Wonderly BA, Hartley P, Moreci J, Bennett N, Horvath K, Burk M, Fasano A. Detection of Celiac disease in primary care: a multicenter case-finding study in North America. Am J Gastroenterol. 2007 Jul; 102(7):1454-60. PMID: 17355413.
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  121. Goldberg D, Kryszak D, Fasano A, Green PH. Screening for celiac disease in family members: is follow-up testing necessary? Dig Dis Sci. 2007 Apr; 52(4):1082-6. PMID: 17380406.
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  122. Catassi C, Fabiani E, Iacono G, D'Agate C, Francavilla R, Biagi F, Volta U, Accomando S, Picarelli A, De Vitis I, Pianelli G, Gesuita R, Carle F, Mandolesi A, Bearzi I, Fasano A. A prospective, double-blind, placebo-controlled trial to establish a safe gluten threshold for patients with celiac disease. Am J Clin Nutr. 2007 Jan; 85(1):160-6. PMID: 17209192.
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  123. Fasano A. Systemic autoimmune disorders in celiac disease. Curr Opin Gastroenterol. 2006 Nov; 22(6):674-9. PMID: 17053448.
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  124. Branski D, Fasano A, Troncone R. Latest developments in the pathogenesis and treatment of celiac disease. J Pediatr. 2006 Sep; 149(3):295-300. PMID: 16939736.
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  125. Motlekar NA, Fasano A, Wachtel MS, Youan BB. Zonula occludens toxin synthetic peptide derivative AT1002 enhances in vitro and in vivo intestinal absorption of low molecular weight heparin. J Drug Target. 2006 Jun; 14(5):321-9. PMID: 16882552; PMCID: PMC1994914.
  126. Sapone A, de Magistris L, Pietzak M, Clemente MG, Tripathi A, Cucca F, Lampis R, Kryszak D, Cartenì M, Generoso M, Iafusco D, Prisco F, Laghi F, Riegler G, Carratu R, Counts D, Fasano A. Zonulin upregulation is associated with increased gut permeability in subjects with type 1 diabetes and their relatives. Diabetes. 2006 May; 55(5):1443-9. PMID: 16644703.
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  127. Drago S, El Asmar R, Di Pierro M, Grazia Clemente M, Tripathi A, Sapone A, Thakar M, Iacono G, Carroccio A, D'Agate C, Not T, Zampini L, Catassi C, Fasano A. Gliadin, zonulin and gut permeability: Effects on celiac and non-celiac intestinal mucosa and intestinal cell lines. Scand J Gastroenterol. 2006 Apr; 41(4):408-19. PMID: 16635908.
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  128. Gelfond D, Fasano A. Celiac disease in the pediatric population. Pediatr Ann. 2006 Apr; 35(4):275-9. PMID: 16637556.
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  129. Salama NN, Eddington ND, Fasano A. Tight junction modulation and its relationship to drug delivery. Adv Drug Deliv Rev. 2006 Apr 20; 58(1):15-28. PMID: 16517003.
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  130. Thomas KE, Sapone A, Fasano A, Vogel SN. Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease. J Immunol. 2006 Feb 15; 176(4):2512-21. PMID: 16456012.
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  131. Gadewar S, Fasano A. Celiac disease: is the atypical really typical? Summary of the recent National Institutes of Health Consensus Conference and latest advances. Curr Gastroenterol Rep. 2005 Dec; 7(6):455-61. PMID: 16313875.
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  132. Menon D, Karyekar CS, Fasano A, Lu R, Eddington ND. Enhancement of brain distribution of anticancer agents using DeltaG, the 12 kDa active fragment of ZOT. Int J Pharm. 2005 Dec 08; 306(1-2):122-31. PMID: 16274945.
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  133. De Angelis M, Rizzello CG, Fasano A, Clemente MG, De Simone C, Silano M, De Vincenzi M, Losito I, Gobbetti M. VSL#3 probiotic preparation has the capacity to hydrolyze gliadin polypeptides responsible for Celiac Sprue. Biochim Biophys Acta. 2006 Jan; 1762(1):80-93. PMID: 16311022.
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  134. Gadewar S, Fasano A. Current concepts in the evaluation, diagnosis and management of acute infectious diarrhea. Curr Opin Pharmacol. 2005 Dec; 5(6):559-65. PMID: 16207535.
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  135. Fasano A, Shea-Donohue T. Mechanisms of disease: the role of intestinal barrier function in the pathogenesis of gastrointestinal autoimmune diseases. Nat Clin Pract Gastroenterol Hepatol. 2005 Sep; 2(9):416-22. PMID: 16265432.
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  136. Fasano A, Catassi C. Coeliac disease in children. Best Pract Res Clin Gastroenterol. 2005 Jun; 19(3):467-78. PMID: 15925850.
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  137. Smecuol E, Sugai E, Niveloni S, Vázquez H, Pedreira S, Mazure R, Moreno ML, Label M, Mauriño E, Fasano A, Meddings J, Bai JC. Permeability, zonulin production, and enteropathy in dermatitis herpetiformis. Clin Gastroenterol Hepatol. 2005 Apr; 3(4):335-41. PMID: 15822038.
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  138. Fasano A. Clinical presentation of celiac disease in the pediatric population. Gastroenterology. 2005 Apr; 128(4 Suppl 1):S68-73. PMID: 15825129.
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  139. Watts T, Berti I, Sapone A, Gerarduzzi T, Not T, Zielke R, Fasano A. Role of the intestinal tight junction modulator zonulin in the pathogenesis of type I diabetes in BB diabetic-prone rats. Proc Natl Acad Sci U S A. 2005 Feb 22; 102(8):2916-21. PMID: 15710870; PMCID: PMC549484.
  140. Hill ID, Dirks MH, Liptak GS, Colletti RB, Fasano A, Guandalini S, Hoffenberg EJ, Horvath K, Murray JA, Pivor M, Seidman EG. Guideline for the diagnosis and treatment of celiac disease in children: recommendations of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. J Pediatr Gastroenterol Nutr. 2005 Jan; 40(1):1-19. PMID: 15625418.
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  141. Johnson TC, Diamond B, Memeo L, Negulescu H, Hovhanissyan Z, Verkarre V, Rotterdam H, Fasano A, Caillat-Zucman S, Grosdidier E, Winchester R, Cellier C, Jabri B, Green PH. Relationship of HLA-DQ8 and severity of celiac disease: comparison of New York and Parisian cohorts. Clin Gastroenterol Hepatol. 2004 Oct; 2(10):888-94. PMID: 15476152.
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  142. Salama NN, Fasano A, Thakar M, Eddington ND. The impact of DeltaG on the oral bioavailability of low bioavailable therapeutic agents. J Pharmacol Exp Ther. 2005 Jan; 312(1):199-205. PMID: 15448170.
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  143. Catassi C, Fasano A. Celiac disease as a cause of growth retardation in childhood. Curr Opin Pediatr. 2004 Aug; 16(4):445-9. PMID: 15273508.
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  144. Salazar-Lindo E, Allen S, Brewster DR, Elliott EJ, Fasano A, Phillips AD, Sanderson IR, Tarr PI. Intestinal infections and environmental enteropathy: Working Group report of the second World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2004 Jun; 39 Suppl 2:S662-9. PMID: 15184767.
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  145. Salama NN, Fasano A, Thakar M, Eddington ND. The effect of delta G on the transport and oral absorption of macromolecules. J Pharm Sci. 2004 May; 93(5):1310-9. PMID: 15067707.
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  146. Fasano A, Nataro JP. Intestinal epithelial tight junctions as targets for enteric bacteria-derived toxins. Adv Drug Deliv Rev. 2004 Apr 19; 56(6):795-807. PMID: 15063590.
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  147. Fasano A. Celiac disease--how to handle a clinical chameleon. N Engl J Med. 2003 Jun 19; 348(25):2568-70. PMID: 12815143.
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  148. Marinaro M, Fasano A, De Magistris MT. Zonula occludens toxin acts as an adjuvant through different mucosal routes and induces protective immune responses. Infect Immun. 2003 Apr; 71(4):1897-902. PMID: 12654806; PMCID: PMC152047.
  149. Fasano A. Bioterrorism and biological warfare: not only a respiratory affair. J Pediatr Gastroenterol Nutr. 2003 Mar; 36(3):305-6. PMID: 12669708.
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  150. Fasano A, Berti I, Gerarduzzi T, Not T, Colletti RB, Drago S, Elitsur Y, Green PH, Guandalini S, Hill ID, Pietzak M, Ventura A, Thorpe M, Kryszak D, Fornaroli F, Wasserman SS, Murray JA, Horvath K. Prevalence of celiac disease in at-risk and not-at-risk groups in the United States: a large multicenter study. Arch Intern Med. 2003 Feb 10; 163(3):286-92. PMID: 12578508.
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  151. Karyekar CS, Fasano A, Raje S, Lu R, Dowling TC, Eddington ND. Zonula occludens toxin increases the permeability of molecular weight markers and chemotherapeutic agents across the bovine brain microvessel endothelial cells. J Pharm Sci. 2003 Feb; 92(2):414-23. PMID: 12532391.
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  152. Salama NN, Fasano A, Lu R, Eddington ND. Effect of the biologically active fragment of zonula occludens toxin, delta G, on the intestinal paracellular transport and oral absorption of mannitol. Int J Pharm. 2003 Jan 30; 251(1-2):113-21. PMID: 12527181.
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  153. El Asmar R, Panigrahi P, Bamford P, Berti I, Not T, Coppa GV, Catassi C, Fasano A, El Asmar R. Host-dependent zonulin secretion causes the impairment of the small intestine barrier function after bacterial exposure. Gastroenterology. 2002 Nov; 123(5):1607-15. PMID: 12404235.
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  154. Alaedini A, Green PH, Sander HW, Hays AP, Gamboa ET, Fasano A, Sonnenberg M, Lewis LD, Latov N. Ganglioside reactive antibodies in the neuropathy associated with celiac disease. J Neuroimmunol. 2002 Jun; 127(1-2):145-8. PMID: 12044986.
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  155. Catassi C, Fasano A. New developments in childhood celiac disease. Curr Gastroenterol Rep. 2002 Jun; 4(3):238-43. PMID: 12010625.
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  156. Rossi M, Maurano F, Luongo D, Fasano A, Uzzau S, Auricchio S, Troncone R. Zonula occludens toxin (Zot) interferes with the induction of nasal tolerance to gliadin. Immunol Lett. 2002 May 01; 81(3):217-21. PMID: 11947928.
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  157. Davidson G, Barnes G, Bass D, Cohen M, Fasano A, Fontaine O, Guandalini S. Infectious diarrhea in children: Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and Nutrition. J Pediatr Gastroenterol Nutr. 2002; 35 Suppl 2:S143-50. PMID: 12192183.
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