Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Alessio Fasano, M.D.

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Other Positions
Title
Institution
Department

Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R56AI156711 (FASANO, ALESSIO) Jun 15, 2016 - Aug 31, 2022
    NIH
    The Celiac Disease Genome, Environment, Microbiome, and Metabolome (CD-GEMM) prospective cohort study
    Role: Principal Investigator
  2. R01DK104344 (FASANO, ALESSIO) Jun 15, 2016 - May 31, 2021
    NIH
    Microbiome-derived Metabolites Linked to Celiac Disease Onset in Infants at Risk
    Role: Principal Investigator
  3. R34AT006945 (VISCARDI, ROSE MARIE) Sep 1, 2011 - Jun 30, 2015
    NIH
    Effect of Lactobacillus GG on gut permeability and microbiome in VLBW neonates
    Role: Principal Investigator
  4. U19AI090873 (KAPER, JAMES B) Jul 20, 2010 - Jun 30, 2015
    NIH/NIAID
    Severe Enteric Disease: Pathogenesis and Response
    Role: Co-Principal Investigator
  5. U19AI082655 (SZTEIN, MARCELO B.) Jun 18, 2009 - May 31, 2019
    NIH/NIAID
    Mucusal and Systemic Immunity, Vaccines and Microbiota Interplay in Humans
    Role: Co-Principal Investigator

Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Su CW, Chen CY, Mao T, Chen N, Steudel N, Jiao L, Lan J, Fasano A, Walker WA, Shi HN. Maternal helminth infection protects offspring from high-fat-diet-induced obesity through altered microbiota and SCFAs. Cell Mol Immunol. 2023 Feb 14. PMID: 36788341.
    Citations:    Fields:    
  2. Valitutti F, Leonard MM, Kenyon V, Montuori M, Piemontese P, Francavilla R, Malamisura B, Norsa L, Calvi A, Lionetti ME, Baldassarre M, Trovato CM, Perrone M, Passaro T, Sansotta N, Crocco M, Morelli A, Raguseo LC, Malerba F, Elli L, Cristofori F, Catassi C, Fasano A. Early Antibody Dynamics in a Prospective Cohort of Children At Risk of Celiac Disease. Am J Gastroenterol. 2023 Mar 01; 118(3):574-577. PMID: 36727859.
    Citations:    Fields:    
  3. Yonker LM, Swank Z, Bartsch YC, Burns MD, Kane A, Boribong BP, Davis JP, Loiselle M, Novak T, Senussi Y, Cheng CA, Burgess E, Edlow AG, Chou J, Dionne A, Balaguru D, Lahoud-Rahme M, Arditi M, Julg B, Randolph AG, Alter G, Fasano A, Walt DR. Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis. Circulation. 2023 Jan 04. PMID: 36597886.
    Citations: 3     Fields:    
  4. Di Micco S, Di Sarno V, Rossi M, Vestuto V, Konno T, Novi S, Tecce MF, Napolitano V, Ciaglia T, Vitale A, Gomez-Monterrey IM, Bifulco G, Bertamino A, Ostacolo C, Blasi P, Fasano A, Campiglia P, Musella S. In Silico Identification and In Vitro Evaluation of New ABCG2 Transporter Inhibitors as Potential Anticancer Agents. Int J Mol Sci. 2022 Dec 31; 24(1). PMID: 36614168; PMCID: PMC9820944.
    Citations:    Fields:    Translation:HumansCells
  5. Asbjornsdottir B, Miranda-Ribera A, Fiorentino M, Konno T, Cetinbas M, Lan J, Sadreyev RI, Gudmundsson LS, Gottfredsson M, Lauth B, Birgisdottir BE, Fasano A. Prophylactic Effect of Bovine Colostrum on Intestinal Microbiota and Behavior in Wild-Type and Zonulin Transgenic Mice. Biomedicines. 2022 Dec 29; 11(1). PMID: 36672598; PMCID: PMC9855927.
    Citations:    
  6. Bartsch YC, St Denis KJ, Kaplonek P, Kang J, Lam EC, Burns MD, Farkas EJ, Davis JP, Boribong BP, Edlow AG, Fasano A, Shreffler WG, Zavadska D, Johnson M, Goldblatt D, Balazs AB, Yonker LM, Alter G. SARS-CoV-2 mRNA vaccination elicits robust antibody responses in children. Sci Transl Med. 2022 11 23; 14(672):eabn9237. PMID: 35881018; PMCID: PMC9348753.
    Citations:    Fields:    
  7. Boribong BP, LaSalle TJ, Bartsch YC, Ellett F, Loiselle ME, Davis JP, Gonye ALK, Sykes DB, Hajizadeh S, Kreuzer J, Pillai S, Haas W, Edlow AG, Fasano A, Alter G, Irimia D, Sade-Feldman M, Yonker LM. Neutrophil profiles of pediatric COVID-19 and multisystem inflammatory syndrome in children. Cell Rep Med. 2022 12 20; 3(12):100848. PMID: 36476388; PMCID: PMC9676175.
    Citations: 2     Fields:    Translation:HumansCells
  8. Konno T, Martinez EE, Ji J, Miranda-Ribera A, Fiorentino MR, Fasano A. Human coagulation factor X and CD5 antigen-like are potential new members of the zonulin family proteins. Biochem Biophys Res Commun. 2023 01 01; 638:127-133. PMID: 36446155; PMCID: PMC9797450.
    Citations:    Fields:    Translation:HumansCells
  9. Beopoulos A, Géa M, Fasano A, Iris F. Autism spectrum disorders pathogenesis: Toward a comprehensive model based on neuroanatomic and neurodevelopment considerations. Front Neurosci. 2022; 16:988735. PMID: 36408388; PMCID: PMC9671112.
    Citations:    
  10. Di Micco S, Rahimova R, Sala M, Scala MC, Vivenzio G, Musella S, Andrei G, Remans K, Mammri L, Snoeck R, Bifulco G, Di Matteo F, Vestuto V, Campiglia P, Márquez JA, Fasano A. Rational design of the zonulin inhibitor AT1001 derivatives as potential anti SARS-CoV-2. Eur J Med Chem. 2022 Dec 15; 244:114857. PMID: 36332548; PMCID: PMC9579148.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  11. Burns MD, Muir C, Atyeo C, Davis JP, Demidkin S, Akinwunmi B, Fasano A, Gray KJ, Alter G, Shook LL, Edlow AG, Yonker LM. Relationship between Anti-Spike Antibodies and Risk of SARS-CoV-2 Infection in Infants Born to COVID-19 Vaccinated Mothers. Vaccines (Basel). 2022 Oct 11; 10(10). PMID: 36298561; PMCID: PMC9610427.
    Citations: 2     
  12. Seidita A, Mansueto P, Giuliano A, Chiavetta M, Mandreucci F, Soresi M, Pistone M, Compagnoni S, Castellucci D, Bisso G, Faraci F, Maestri S, Disclafani R, Sapone A, Fasano A, Carroccio A. Potential tolerability of ancient grains in non-celiac wheat sensitivity patients: A preliminary evaluation. Front Med (Lausanne). 2022; 9:995019. PMID: 36250065; PMCID: PMC9554215.
    Citations:    
  13. El Mouzan M, Al-Hussaini A, Serena G, Assiri A, Al Sarkhy A, Al Mofarreh M, Alasmi M, Fasano A. Microbiota profile of new-onset celiac disease in children in Saudi Arabia. Gut Pathog. 2022 Sep 08; 14(1):37. PMID: 36076257; PMCID: PMC9461150.
    Citations:    
  14. Troisi J, Lombardi M, Scala G, Cavallo P, Tayler RS, Symes SJK, Richards SM, Adair DC, Fasano A, McCowan LM, Guida M. A screening test proposal for congenital defects based on maternal serum metabolomics profile. Am J Obstet Gynecol. 2023 03; 228(3):342.e1-342.e12. PMID: 36075482.
    Citations: 1     Fields:    Translation:Humans
  15. Asbjornsdottir B, Lauth B, Fasano A, Thorsdottir I, Karlsdottir I, Gudmundsson LS, Gottfredsson M, Smarason O, Sigurdardottir S, Halldorsson TI, Marteinsson VT, Gudmundsdottir V, Birgisdottir BE. Meals, Microbiota and Mental Health in Children and Adolescents (MMM-Study): A protocol for an observational longitudinal case-control study. PLoS One. 2022; 17(9):e0273855. PMID: 36048886; PMCID: PMC9436124.
    Citations:    Fields:    Translation:Humans
  16. Ali Ibrahim A, Kenyon V, Fasano A, Leonard MM. Budesonide and the Gluten Containing Elimination Diet as Treatments for Non-responsive Celiac Disease in Children. J Pediatr Gastroenterol Nutr. 2022 11 01; 75(5):616-622. PMID: 36305882; PMCID: PMC9627632.
    Citations:    Fields:    Translation:Humans
  17. Atyeo C, Shook LL, Nziza N, Deriso EA, Muir C, Baez AM, Lima RS, Demidkin S, Brigida S, De Guzman RM, Burns MD, Balazs AB, Fasano A, Yonker LM, Gray KJ, Alter G, Edlow AG. COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant women. Am J Obstet Gynecol. 2023 01; 228(1):68.e1-68.e12. PMID: 35868417; PMCID: PMC9295313.
    Citations:    Fields:    
  18. Yonker LM, Badaki-Makun O, Arya P, Boribong BP, Moraru G, Fenner B, Rincon J, Hopke A, Rogers B, Hinson J, Fasano A, Lee L, Kehoe SM, Larson SD, Chavez H, Levin S, Moldawer LL, Irimia D. Correction to: Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications. BMC Infect Dis. 2022 Jul 07; 22(1):595. PMID: 35799137; PMCID: PMC9260969.
    Citations:    Fields:    
  19. Stuart CM, Varatharaj A, Winberg ME, Galea P, Larsson HBW, Cramer SP, Fasano A, Maherally Z, Pilkington GJ, Keita ÅV, Galea I. Zonulin and blood-brain barrier permeability are dissociated in humans. Clin Transl Med. 2022 07; 12(7):e965. PMID: 35808833; PMCID: PMC9270641.
    Citations:    Fields:    Translation:Humans
  20. Atyeo CG, Shook LL, Brigida S, De Guzman RM, Demidkin S, Muir C, Akinwunmi B, Baez AM, Sheehan ML, McSweeney E, Burns MD, Nayak R, Kumar MK, Patel CD, Fialkowski A, Cvrk D, Goldfarb IT, Yonker LM, Fasano A, Balazs AB, Elovitz MA, Gray KJ, Alter G, Edlow AG. Maternal immune response and placental antibody transfer after COVID-19 vaccination across trimester and platforms. Nat Commun. 2022 06 28; 13(1):3571. PMID: 35764643; PMCID: PMC9239994.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  21. Aiemjoy K, Seidman JC, Saha S, Munira SJ, Islam Sajib MS, Sium SMA, Sarkar A, Alam N, Zahan FN, Kabir MS, Tamrakar D, Vaidya K, Shrestha R, Shakya J, Katuwal N, Shrestha S, Yousafzai MT, Iqbal J, Dehraj IF, Ladak Y, Maria N, Adnan M, Pervaiz S, Carter AS, Longley AT, Fraser C, Ryan ET, Nodoushani A, Fasano A, Leonard MM, Kenyon V, Bogoch II, Jeon HJ, Haselbeck A, Park SE, Zellweger RM, Marks F, Owusu-Dabo E, Adu-Sarkodie Y, Owusu M, Teunis P, Luby SP, Garrett DO, Qamar FN, Saha SK, Charles RC, Andrews JR. Estimating typhoid incidence from community-based serosurveys: a multicohort study. Lancet Microbe. 2022 08; 3(8):e578-e587. PMID: 35750069; PMCID: PMC9329131.
    Citations:    
  22. Yonker LM, Badaki-Makun O, Arya P, Boribong BP, Moraru G, Fenner B, Rincon J, Hopke A, Rogers B, Hinson J, Fasano A, Lee L, Kehoe SM, Larson SD, Chavez H, Levin S, Moldawer LL, Irimia D. Monocyte anisocytosis increases during multisystem inflammatory syndrome in children with cardiovascular complications. BMC Infect Dis. 2022 Jun 20; 22(1):563. PMID: 35725405; PMCID: PMC9208352.
    Citations: 1     Fields:    Translation:HumansCells
  23. Rostami K, Ensari A, Marsh MN, Srivastava A, Villanacci V, Carroccio A, Asadzadeh Aghdaei H, Bai JC, Bassotti G, Becheanu G, Bell P, Di Bella C, Bozzola AM, Cadei M, Casella G, Catassi C, Ciacci C, Apostol Ciobanu DG, Cross SS, Danciu M, Das P, Del Sordo R, Drage M, Elli L, Fasano A, Florena AM, Fusco N, Going JJ, Guandalini S, Hagen CE, Hayman DTS, Ishaq S, Jericho H, Johncilla M, Johnson M, Kaukinen K, Levene A, Liptrot S, Lu L, Makharia GK, Mathews S, Mazzarella G, Maxim R, La Win Myint K, Mohaghegh-Shalmani H, Moradi A, Mulder CJJ, Ray R, Ricci C, Rostami-Nejad M, Sapone A, Sanders DS, Taavela J, Volta U, Walker M, Derakhshan M. Gluten Induces Subtle Histological Changes in Duodenal Mucosa of Patients with Non-Coeliac Gluten Sensitivity: A Multicentre Study. Nutrients. 2022 Jun 15; 14(12). PMID: 35745217; PMCID: PMC9230100.
    Citations:    Fields:    Translation:Humans
  24. Martinez EE, Mehta NM, Fasano A. The Zonulin Pathway as a Potential Mediator of Gastrointestinal Dysfunction in Critical Illness. Pediatr Crit Care Med. 2022 09 01; 23(9):e424-e428. PMID: 35543388.
    Citations:    Fields:    
  25. Burns MD, Boribong BP, Bartsch YC, Loiselle M, St Denis KJ, Sheehan ML, Chen JW, Davis JP, Lima R, Edlow AG, Fasano A, Balazs AB, Alter G, Yonker LM. Durability and Cross-Reactivity of SARS-CoV-2 mRNA Vaccine in Adolescent Children. Vaccines (Basel). 2022 Mar 23; 10(4). PMID: 35455241; PMCID: PMC9032590.
    Citations: 1     
  26. Shook LL, Atyeo CG, Yonker LM, Fasano A, Gray KJ, Alter G, Edlow AG. Durability of Anti-Spike Antibodies in Infants After Maternal COVID-19 Vaccination or Natural Infection. JAMA. 2022 03 15; 327(11):1087-1089. PMID: 35129576; PMCID: PMC8822441.
    Citations: 7     Fields:    Translation:Humans
  27. Yonker LM, Swank Z, Gilboa T, Senussi Y, Kenyon V, Papadakis L, Boribong BP, Carroll RW, Walt DR, Fasano A. Zonulin Antagonist, Larazotide (AT1001), As an Adjuvant Treatment for Multisystem Inflammatory Syndrome in Children: A Case Series. Crit Care Explor. 2022 Feb; 10(2):e0641. PMID: 35211683; PMCID: PMC8860335.
    Citations: 1     
  28. Burns MD, Boribong BP, Bartsch YC, Loiselle M, Davis JP, Lima R, Edlow AG, Fasano A, Alter G, Yonker LM. Durability and cross-reactivity of SARS-CoV-2 mRNA vaccine in adolescent children. medRxiv. 2022 Feb 16. PMID: 35194616; PMCID: PMC8863160.
    Citations:    
  29. Bartsch YC, St Denis KJ, Kaplonek P, Kang J, Lam EC, Burns MD, Farkas EJ, Davis JP, Boribong BP, Edlow AG, Fasano A, Shreffler W, Zavadska D, Johnson M, Goldblatt D, Balazs AB, Yonker LM, Alter G. Comprehensive antibody profiling of mRNA vaccination in children. bioRxiv. 2022 Jan 04. PMID: 35018376; PMCID: PMC8750651.
    Citations:    
  30. Farina F, Pisapia L, Laezza M, Serena G, Rispo A, Ricciolino S, Gianfrani C, Fasano A, Del Pozzo G. Effect of Gliadin Stimulation on HLA-DQ2.5 Gene Expression in Macrophages from Adult Celiac Disease Patients. Biomedicines. 2021 Dec 29; 10(1). PMID: 35052743; PMCID: PMC8773327.
    Citations: 1     
  31. Beopoulos A, Gea M, Fasano A, Iris F. Autonomic Nervous System Neuroanatomical Alterations Could Provoke and Maintain Gastrointestinal Dysbiosis in Autism Spectrum Disorder (ASD): A Novel Microbiome-Host Interaction Mechanistic Hypothesis. Nutrients. 2021 Dec 24; 14(1). PMID: 35010940; PMCID: PMC8746684.
    Citations:    Fields:    Translation:Humans