Harvard Catalyst Profiles

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Daniel Joseph Balick, Ph.D.


Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Balick DJ. A field theoretic approach to non-equilibrium population genetics in the strong selection regime. bioRxiv. 2023 Jan 19. PMID: 36711507; PMCID: PMC9882232.
  2. Balick DJ, Jordan DM, Sunyaev S, Do R. Overcoming constraints on the detection of recessive selection in human genes from population frequency data. Am J Hum Genet. 2022 01 06; 109(1):33-49. PMID: 34951958; PMCID: PMC8764206.
    Citations:    Fields:    Translation:Humans
  3. Radke DW, Sul JH, Balick DJ, Akle S, Green RC, Sunyaev SR. Purifying selection on noncoding deletions of human regulatory loci detected using their cellular pleiotropy. Genome Res. 2021 06; 31(6):935-946. PMID: 33963077; PMCID: PMC8168579.
    Citations: 2     Fields:    Translation:HumansCells
  4. Vy HMT, Jordan DM, Balick DJ, Do R. Probing the aggregated effects of purifying selection per individual on 1,380 medical phenotypes in the UK Biobank. PLoS Genet. 2021 01; 17(1):e1009337. PMID: 33493176.
    Citations:    Fields:    Translation:Humans
  5. Weghorn D, Balick DJ, Cassa C, Kosmicki JA, Daly MJ, Beier DR, Sunyaev SR. Applicability of the Mutation-Selection Balance Model to Population Genetics of Heterozygous Protein-Truncating Variants in Humans. Mol Biol Evol. 2019 08 01; 36(8):1701-1710. PMID: 31004148; PMCID: PMC6738481.
    Citations: 5     Fields:    Translation:Humans
  6. Schoech AP, Jordan DM, Loh PR, Gazal S, O'Connor LJ, Balick DJ, Palamara PF, Finucane HK, Sunyaev SR, Price AL. Quantification of frequency-dependent genetic architectures in 25 UK Biobank traits reveals action of negative selection. Nat Commun. 2019 02 15; 10(1):790. PMID: 30770844.
    Citations: 32     Fields:    Translation:Humans
  7. Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR. Reply to 'Selective effects of heterozygous protein-truncating variants'. Nat Genet. 2019 01; 51(1):3-4. PMID: 30478437; PMCID: PMC9196138.
    Citations: 1     Fields:    
  8. Cassa CA, Weghorn D, Balick DJ, Jordan DM, Nusinow D, Samocha KE, O'Donnell-Luria A, MacArthur DG, Daly MJ, Beier DR, Sunyaev SR. Estimating the selective effects of heterozygous protein-truncating variants from human exome data. Nat Genet. 2017 May; 49(5):806-810. PMID: 28369035; PMCID: PMC5618255.
    Citations: 50     Fields:    Translation:HumansAnimals
  9. Balick DJ, Do R, Cassa CA, Reich D, Sunyaev SR. Dominance of Deleterious Alleles Controls the Response to a Population Bottleneck. PLoS Genet. 2015 Aug; 11(8):e1005436. PMID: 26317225.
    Citations: 37     Fields:    Translation:HumansAnimals
  10. Do R, Balick D, Li H, Adzhubei I, Sunyaev S, Reich D. No evidence that selection has been less effective at removing deleterious mutations in Europeans than in Africans. Nat Genet. 2015 Feb; 47(2):126-31. PMID: 25581429; PMCID: PMC4310772.
    Citations: 81     Fields:    Translation:HumansAnimals
  11. Goyal S, Balick DJ, Jerison ER, Neher RA, Shraiman BI, Desai MM. Dynamic mutation-selection balance as an evolutionary attractor. Genetics. 2012 Aug; 191(4):1309-19. PMID: 22661327.
    Citations: 32     Fields:    
  12. Good BH, Rouzine IM, Balick DJ, Hallatschek O, Desai MM. Distribution of fixed beneficial mutations and the rate of adaptation in asexual populations. Proc Natl Acad Sci U S A. 2012 Mar 27; 109(13):4950-5. PMID: 22371564.
    Citations: 86     Fields:    
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.