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Steven James Mentzer, M.D.

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Mentoring
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Unpaid research trainee [login at prompt]
Available: 06/27/24, Expires: 06/30/26

A focus of our laboratory is the adaptive and regenerative processes contributing to tissue repair and regeneration. These processes typically involve blood vessel growth (angiogenesis) and changes in the organ surface (mesothelial-mesenchymal transition). The study of these processes involves a multi-scale approach: 1) the regulated expression of genes and molecules, 2) the interactive signaling communication between cells, and 3) the structural/biomechanical relationships leading to adult tissue remodeling (morphogenesis). A recent focus of our approach has been the use of biologic polymers(such as pectin) as tools to explore mesothelial-mesenchymal transition and other fundamental processes essential to normal tissue repair and regeneration. The perturbation of these processes is a major contributor to lung disease and lung cancer.


Research
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The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
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  1. R56HL136476 (MENTZER, STEVEN) Sep 25, 2018 - Aug 31, 2020
    NIH
    Manipulating Tissue Strain in Surgical Repair
    Role: Principal Investigator
  2. R01HL094567 (MENTZER, STEVEN) Dec 1, 2008 - May 31, 2019
    NIH
    Adult Tissue Morphogenesis: Functional Regulation of Intussusceptive Angiogenesis
    Role: Principal Investigator
  3. R01HL075426 (MENTZER, STEVEN J) Sep 26, 2003 - Aug 31, 2009
    NIH
    Physiology of Systemic and Pulmonary Microangiectasias
    Role: Principal Investigator
  4. R01HL047078 (MENTZER, STEVEN J) Jul 2, 1992 - Mar 31, 2009
    NIH
    Microangiectasia Regulation of Lymphocyte Migration
    Role: Principal Investigator
  5. R29HL047078 (MENTZER, STEVEN J) Jul 2, 1992 - Jun 30, 1997
    NIH
    LYMPHOCYTE RECRUITMENT IN LUNG TRANSPLATATION
    Role: Principal Investigator

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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.