Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Mark P. Jedrychowski, Ph.D.


This page shows the publications co-authored by Mark Jedrychowski and Pere Puigserver.
Connection Strength

  1. Peroxisomal-derived ether phospholipids link nucleotides to respirasome assembly. Nat Chem Biol. 2021 Jun; 17(6):703-710.
    View in: PubMed
    Score: 0.244
  2. A cold-stress-inducible PERK/OGT axis controls TOM70-assisted mitochondrial protein import and cristae formation. Cell Metab. 2021 Mar 02; 33(3):598-614.e7.
    View in: PubMed
    Score: 0.242
  3. Tetracyclines promote survival and fitness in mitochondrial disease models. Nat Metab. 2021 01; 3(1):33-42.
    View in: PubMed
    Score: 0.241
  4. Defective NADPH production in mitochondrial disease complex I causes inflammation and cell death. Nat Commun. 2020 06 01; 11(1):2714.
    View in: PubMed
    Score: 0.231
  5. ER and Nutrient Stress Promote Assembly of Respiratory Chain Supercomplexes through the PERK-eIF2a Axis. Mol Cell. 2019 06 06; 74(5):877-890.e6.
    View in: PubMed
    Score: 0.214
  6. Inhibition of the ER stress IRE1a inflammatory pathway protects against cell death in mitochondrial complex I mutant cells. Cell Death Dis. 2018 05 31; 9(6):658.
    View in: PubMed
    Score: 0.201
  7. ERRa Maintains Mitochondrial Oxidative Metabolism and Constitutes an Actionable Target in PGC1a-Elevated Melanomas. Mol Cancer Res. 2017 10; 15(10):1366-1375.
    View in: PubMed
    Score: 0.188
  8. Selective Chemical Inhibition of PGC-1a Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 03 23; 169(1):148-160.e15.
    View in: PubMed
    Score: 0.185
  9. Bromodomain Inhibitors Correct Bioenergetic Deficiency Caused by Mitochondrial Disease Complex I Mutations. Mol Cell. 2016 10 06; 64(1):163-175.
    View in: PubMed
    Score: 0.179
  10. The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1a Transcriptional Coactivator. J Biol Chem. 2016 May 13; 291(20):10635-45.
    View in: PubMed
    Score: 0.173
  11. Cdc2-like kinase 2 suppresses hepatic fatty acid oxidation and ketogenesis through disruption of the PGC-1a and MED1 complex. Diabetes. 2014 May; 63(5):1519-32.
    View in: PubMed
    Score: 0.149
  12. The deacetylase Sirt6 activates the acetyltransferase GCN5 and suppresses hepatic gluconeogenesis. Mol Cell. 2012 Dec 28; 48(6):900-13.
    View in: PubMed
    Score: 0.137
  13. The cAMP/PKA pathway rapidly activates SIRT1 to promote fatty acid oxidation independently of changes in NAD(+). Mol Cell. 2011 Dec 23; 44(6):851-63.
    View in: PubMed
    Score: 0.129
Connection Strength
The connection strength for co-authors is the sum of the scores for each of their shared publications.

Publication scores are based on many factors, including how long ago they were written and whether the person is a first or senior author.
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.