Harvard Catalyst Profiles

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Daniel Benjamin Kopans, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R33CA107863 (KOPANS, DANIEL B) May 1, 2004 - Apr 30, 2007
    Specificity/Sensitivity in Mammographic Screening
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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  1. Kopans DB. Major failings of trial procedures and quality of screening fatally compromise the results of the Canadian National Breast Screening Studies. J Med Screen. 2021 Jun; 28(2):59-62. PMID: 33459171.
    Citations:    Fields:    
  2. Kopans DB. The wisdom trial is based on faulty reasoning and has major design and execution problems. Breast Cancer Res Treat. 2021 Feb; 185(3):549-556. PMID: 33237397.
    Citations:    Fields:    
  3. Kopans DB. Recommendations for breast cancer screening. Lancet Oncol. 2020 11; 21(11):e513. PMID: 33152305.
    Citations:    Fields:    Translation:HumansPHPublic Health
  4. Kopans DB. Lifting the fog of confusion about breast cancer screening guidelines: Surprise - it's about the money! Clin Imaging. 2020 Nov; 67:5-6. PMID: 32497997.
    Citations:    Fields:    Translation:HumansPHPublic Health
  5. Kopans DB, Biggs KW, Pyatt RS, Smetherman D, Friedberg EB. The State of Breast Cancer Screening Guidelines: A Question and Answer Summary. J Am Coll Radiol. 2020 05; 17(5):629-632. PMID: 32113863.
    Citations:    Fields:    
  6. Kopans DB. There Is No Way That the Cancer Detection Rate for Full-Field Digital Mammography Is the Same as for Digital Breast Tomosynthesis. AJR Am J Roentgenol. 2019 Jul; 213(1):W46. PMID: 33497277.
    Citations:    Fields:    
  7. Kopans DB. Deep Learning or Fundamental Descriptors? Radiology. 2018 05; 287(2):728-729. PMID: 29668415.
    Citations:    Fields:    
  8. Kopans DB. Breast cancer screening: Where have we been and where are we going? A personal perspective based on history, data and experience. Clin Imaging. 2018 Mar - Apr; 48:vii-xi. PMID: 29549915.
    Citations:    Fields:    Translation:HumansPHPublic Health
  9. Kopans DB. False Information About Breast Cancer Screening. JAMA Intern Med. 2018 02 01; 178(2):298. PMID: 29404607.
    Citations:    Fields:    Translation:Humans
  10. Kopans DB. Breast cancer screening: Where have we been and where are we going? A personal perspective based on history, data and experience. Clin Imaging. 2018 Jul-Aug; 50:91-95. PMID: 29331672.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  11. Kopans DB. Rebuttal comments. Breast Cancer Res Treat. 2017 11; 166(2):655-656. PMID: 28918479.
    Citations:    Fields:    Translation:Humans
  12. Kopans DB. The Breast Cancer Screening "Arcade" and the "Whack-A-Mole" Efforts to Reduce Access to Screening. Semin Ultrasound CT MR. 2018 Feb; 39(1):2-15. PMID: 29317036.
    Citations: 1     Fields:    Translation:Humans
  13. Monticciolo DL, Newell MS, Hendrick RE, Helvie MA, Moy L, Monsees B, Kopans DB, Eby PR, Sickles EA. Breast Cancer Screening for Average-Risk Women: Recommendations From the ACR Commission on Breast Imaging. J Am Coll Radiol. 2017 Sep; 14(9):1137-1143. PMID: 28648873.
    Citations: 27     Fields:    Translation:HumansPHPublic Health
  14. Kopans DB. The Canadian National Breast Screening Studies are compromised and their results are unreliable. They should not factor into decisions about breast cancer screening. Breast Cancer Res Treat. 2017 Aug; 165(1):9-15. PMID: 28528449.
    Citations: 2     Fields:    Translation:Humans
  15. Zimmermann BB, Deng B, Singh B, Martino M, Selb J, Fang Q, Sajjadi AY, Cormier J, Moore RH, Kopans DB, Boas DA, Saksena MA, Carp SA. Multimodal breast cancer imaging using coregistered dynamic diffuse optical tomography and digital breast tomosynthesis. J Biomed Opt. 2017 04 01; 22(4):46008. PMID: 28447102.
    Citations: 8     Fields:    Translation:Humans
  16. Kopans DB. More misinformation on breast cancer screening. Gland Surg. 2017 Feb; 6(1):125-129. PMID: 28210564.
    Citations: 1     
  17. Kopans DB. Breast-Cancer Tumor Size and Screening Effectiveness. N Engl J Med. 2017 01 05; 376(1):93-4. PMID: 28060475.
    Citations:    Fields:    Translation:HumansPHPublic Health
  18. Kopans DB. Point: The New England Journal of Medicine Article Suggesting Overdiagnosis From Mammography Screening Is Scientifically Incorrect and Should Be Withdrawn. J Am Coll Radiol. 2016 11; 13(11S):R50-R52. PMID: 27814814.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  19. Kopans DB. The Faulty Analysis of Breast Cancer Screening Data. Acad Radiol. 2016 Jan; 23(1):116-7. PMID: 26598484.
    Citations: 1     Fields:    Translation:Humans
  20. Vedantham S, Karellas A, Vijayaraghavan GR, Kopans DB. Digital Breast Tomosynthesis: State of the Art. Radiology. 2015 Dec; 277(3):663-84. PMID: 26599926.
    Citations: 26     Fields:    Translation:Humans
  21. Kopans DB. "Off Label" Use of FDA-Approved Devices and Digital Breast Tomosynthesis. AJR Am J Roentgenol. 2015 Nov; 205(5):1149-51. PMID: 26496566.
    Citations:    Fields:    Translation:HumansPHPublic Health
  22. Kopans DB. Breast cancer screening panels continue to confuse the facts and inject their own biases. Curr Oncol. 2015 Oct; 22(5):e376-9. PMID: 26628879.
    Citations: 4     Fields:    
  23. Deng B, Fradkin M, Rouet JM, Moore RH, Kopans DB, Boas DA, Lundqvist M, Fang Q. Characterizing breast lesions through robust multimodal data fusion using independent diffuse optical and x-ray breast imaging. J Biomed Opt. 2015 Aug; 20(8):80502. PMID: 26263413.
    Citations: 3     Fields:    Translation:Humans
  24. Kopans DB. The UK Age Trial: screening women in their forties. Lancet Oncol. 2015 Sep; 16(9):1012-1013. PMID: 26206145.
    Citations: 1     Fields:    Translation:Humans
  25. Kopans DB. An open letter to panels that are deciding guidelines for breast cancer screening. Breast Cancer Res Treat. 2015 May; 151(1):19-25. PMID: 25868866.
    Citations: 9     Fields:    Translation:Humans
  26. Kopans DB. Study "guesstimated" how many cancers would have occurred without mammography screening. BMJ. 2014 Nov 25; 349:g6824. PMID: 25424500.
    Citations: 1     Fields:    Translation:Humans
  27. Kopans DB. Reply to "Tomosynthesis assisting in localization of breast lesions for ultrasound targeting seen on one mammographic view only". AJR Am J Roentgenol. 2014 Nov; 203(5):W556. PMID: 25341176.
    Citations:    Fields:    Translation:Humans
  28. Kopans DB, Webb ML, Cady B. The 20-year effort to reduce access to mammography screening: historical facts dispute a commentary in Cancer. Cancer. 2014 Sep 15; 120(18):2792-9. PMID: 24925233.
    Citations: 2     Fields:    Translation:Humans
  29. Kopans DB. A new era in mammography screening. Radiology. 2014 Jun; 271(3):629-31. PMID: 24848957.
    Citations: 2     Fields:    Translation:HumansPHPublic Health
  30. Kopans DB. Digital breast tomosynthesis from concept to clinical care. AJR Am J Roentgenol. 2014 Feb; 202(2):299-308. PMID: 24450669.
    Citations: 25     Fields:    Translation:Humans
  31. Kopans DB. Arguments against mammography screening continue to be based on faulty science. Oncologist. 2014 Feb; 19(2):107-12. PMID: 24536051.
    Citations: 13     Fields:    Translation:Humans
  32. Webb ML, Kopans DB, Cady B. Reply to A failure analysis of invasive breast cancer: most deaths from disease occur in women not regularly screened. Cancer. 2014 Sep 15; 120(18):2937-8. PMID: 24353038.
    Citations: 2     Fields:    Translation:Humans
  33. Webb ML, Cady B, Michaelson JS, Bush DM, Calvillo KZ, Kopans DB, Smith BL. A failure analysis of invasive breast cancer: most deaths from disease occur in women not regularly screened. Cancer. 2014 Sep 15; 120(18):2839-46. PMID: 24018987.
    Citations: 24     Fields:    Translation:Humans
  34. Hall FM, Kopans DB, Sadowsky NL, Homer MJ. Development of wire localization for occult breast lesions: Boston remembrances. Radiology. 2013 Sep; 268(3):622-7. PMID: 23970507.
    Citations: 2     Fields:    Translation:Humans
  35. Kopans DB. Digital breast tomosynthesis: a better mammogram. Radiology. 2013 Jun; 267(3):968-9. PMID: 23704296.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  36. Kopans DB. Point: The New England Journal of Medicine article suggesting overdiagnosis from mammography screening is scientifically incorrect and should be withdrawn. J Am Coll Radiol. 2013 May; 10(5):317-9; discussion 323. PMID: 23542028.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  37. Gupta S, Vij A, Cafiero E, Bloom D, Agarwal S, Donelan K, Kopans D, Saini S. Retail venue based screening mammography: assessment of women's preferences. Acad Radiol. 2012 Oct; 19(10):1268-72. PMID: 22958721.
    Citations: 4     Fields:    Translation:HumansPHPublic Health
  38. Kopans DB. Do not jump too quickly to conclusions. Breast Cancer Res. 2012 Jul 23; 14(4):108. PMID: 22824314.
    Citations:    Fields:    Translation:HumansPHPublic Health
  39. Kopans DB. Not so fast: the use of incomplete data to devalue the role of mammography screening. Breast Cancer Res Treat. 2012 May; 133(1):399. PMID: 22331480.
    Citations:    Fields:    Translation:Humans
  40. Vazquez-Caruncho M. Overdiagnosis and screening mammography. Radiology. 2012 Feb; 262(2):727-8; author reply 728-9. PMID: 22282189.
    Citations:    Fields:    Translation:HumansPHPublic Health
  41. Kopans DB. Just the facts: mammography saves lives with little if any radiation risk to the mature breast. Health Phys. 2011 Nov; 101(5):578-82. PMID: 21979544.
    Citations: 3     Fields:    Translation:HumansPHPublic Health
  42. Kopans D, Gavenonis S, Halpern E, Moore R. Calcifications in the breast and digital breast tomosynthesis. Breast J. 2011 Nov-Dec; 17(6):638-44. PMID: 21906207.
    Citations: 29     Fields:    Translation:Humans
  43. Kopans DB, Smith RA, Duffy SW. Mammographic screening and "overdiagnosis". Radiology. 2011 Sep; 260(3):616-20. PMID: 21846757.
    Citations: 17     Fields:    Translation:HumansPHPublic Health
  44. Kopans DB. Screening for breast cancer among women in their 40s. Lancet Oncol. 2010 Dec; 11(12):1108-9. PMID: 21126682.
    Citations: 1     Fields:    Translation:Humans
  45. Fang Q, Selb J, Carp SA, Boverman G, Miller EL, Brooks DH, Moore RH, Kopans DB, Boas DA. Combined optical and X-ray tomosynthesis breast imaging. Radiology. 2011 Jan; 258(1):89-97. PMID: 21062924.
    Citations: 78     Fields:    Translation:Humans
  46. Kopans DB. The U.S. Preventive Services Task Force guidelines are not supported by the scientific evidence. Radiology. 2010 Oct; 257(1):294-5; author reply 295. PMID: 20851947.
    Citations:    Fields:    Translation:HumansPHPublic Health
  47. Kopans DB. The 2009 US Preventive Services Task Force (USPSTF) guidelines are not supported by science: the scientific support for mammography screening. Radiol Clin North Am. 2010 Sep; 48(5):843-57. PMID: 20868889.
    Citations: 6     Fields:    Translation:HumansPHPublic Health
  48. Fang Q, Moore RH, Kopans DB, Boas DA. Compositional-prior-guided image reconstruction algorithm for multi-modality imaging. Biomed Opt Express. 2010 Jul 16; 1(1):223-235. PMID: 21258460.
    Citations: 8     
  49. Kopans DB. The 2009 U.S. Preventive Services Task Force guidelines ignore important scientific evidence and should be revised or withdrawn. Radiology. 2010 Jul; 256(1):15-20. PMID: 20574081.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  50. Kopans DB. Re: "Saving lives: mammograms, breast cancer, and health insurance reform". J Am Coll Radiol. 2010 Jul; 7(7):545; author reply 545-6. PMID: 20630396.
    Citations:    Fields:    Translation:Humans
  51. Chan HP, Wu YT, Sahiner B, Wei J, Helvie MA, Zhang Y, Moore RH, Kopans DB, Hadjiiski L, Way T. Characterization of masses in digital breast tomosynthesis: comparison of machine learning in projection views and reconstructed slices. Med Phys. 2010 Jul; 37(7):3576-86. PMID: 20831065.
    Citations: 7     Fields:    Translation:Humans
  52. Kopans DB. Re: "Quality of life and diagnostic imaging outcomes". J Am Coll Radiol. 2010 Jul; 7(7):546; author reply 546-7. PMID: 20630398.
    Citations:    Fields:    Translation:Humans
  53. Kopans DB. The recent US preventive services task force guidelines are not supported by the scientific evidence and should be rescinded. J Am Coll Radiol. 2010 Apr; 7(4):260-4. PMID: 20362940.
    Citations: 3     Fields:    Translation:Humans
  54. Lee JM, McMahon PM, Kong CY, Kopans DB, Ryan PD, Ozanne EM, Halpern EF, Gazelle GS. Cost-effectiveness of breast MR imaging and screen-film mammography for screening BRCA1 gene mutation carriers. Radiology. 2010 Mar; 254(3):793-800. PMID: 20177093.
    Citations: 20     Fields:    Translation:HumansPHPublic Health
  55. Lee CH, Dershaw DD, Kopans D, Evans P, Monsees B, Monticciolo D, Brenner RJ, Bassett L, Berg W, Feig S, Hendrick E, Mendelson E, D'Orsi C, Sickles E, Burhenne LW. Breast cancer screening with imaging: recommendations from the Society of Breast Imaging and the ACR on the use of mammography, breast MRI, breast ultrasound, and other technologies for the detection of clinically occult breast cancer. J Am Coll Radiol. 2010 Jan; 7(1):18-27. PMID: 20129267.
    Citations: 163     Fields:    Translation:HumansPHPublic Health
  56. Kopans DB. Mammography: yet another challenge. Radiology. 2009 Dec; 253(3):587-9. PMID: 19952020.
    Citations:    Fields:    Translation:HumansPHPublic Health
  57. Sidky EY, Pan X, Reiser IS, Nishikawa RM, Moore RH, Kopans DB. Enhanced imaging of microcalcifications in digital breast tomosynthesis through improved image-reconstruction algorithms. Med Phys. 2009 Nov; 36(11):4920-32. PMID: 19994501.
    Citations: 47     Fields:    Translation:Humans
  58. Wheeler AJ, Zhang AY, Drohan B, Lawrence C, Roche C, Kopans DB, Moore RH, Smith BL, Sharko J, Kevin HS. Predicting risk of developing invasive breast cancer in the African American female population. J Clin Oncol. 2009 May 20; 27(15_suppl):11080. PMID: 27963168.
  59. Schwartz GF, Hughes KS, Lynch HT, Fabian CJ, Fentiman IS, Robson ME, Domchek SM, Hartmann LC, Holland R, Winchester DJ, Anderson BO, Arun BK, Bartelink H, Bernard P, Bonanni B, Cady B, Clough KB, Feig SA, Heywang-Köbrunner SH, Howell A, Isaacs C, Kopans DB, Mansel RE, Masood S, Palazzo JP, Pressman PI, Solin LJ, Untch M. Proceedings of the international consensus conference on breast cancer risk, genetics, & risk management, April, 2007. Breast J. 2009 Jan-Feb; 15(1):4-16. PMID: 19141130.
    Citations: 10     Fields:    Translation:Humans
  60. Fang Q, Carp SA, Selb J, Boverman G, Zhang Q, Kopans DB, Moore RH, Miller EL, Brooks DH, Boas DA. Combined optical imaging and mammography of the healthy breast: optical contrast derived from breast structure and compression. IEEE Trans Med Imaging. 2009 Jan; 28(1):30-42. PMID: 19116186.
    Citations: 48     Fields:    Translation:Humans
  61. Kao TJ, Boverman G, Kim BS, Isaacson D, Saulnier GJ, Newell JC, Choi MH, Moore RH, Kopans DB. Regional admittivity spectra with tomosynthesis images for breast cancer detection: preliminary patient study. IEEE Trans Med Imaging. 2008 Dec; 27(12):1762-8. PMID: 19033092.
    Citations: 6     Fields:    Translation:Humans
  62. Murphy CD, Lee JM, Drohan B, Euhus DM, Kopans DB, Gadd MA, Rafferty EA, Specht MC, Smith BL, Hughes KS. The American Cancer Society guidelines for breast screening with magnetic resonance imaging: an argument for genetic testing. Cancer. 2008 Dec 01; 113(11):3116-20. PMID: 18932252.
    Citations: 8     Fields:    Translation:Humans
  63. Kopans DB. The science is needed. Radiology. 2008 Nov; 249(2):719; author reply 719-20. PMID: 18936323.
    Citations:    Fields:    Translation:HumansPHPublic Health
  64. Kopans DB, Rusby JE. Cutaneous caves and subcutaneous adipose columns in the breast: radiologic-pathologic correlation. Radiology. 2008 Dec; 249(3):779-84. PMID: 18849506.
    Citations: 3     Fields:    Translation:Humans
  65. Carp SA, Selb J, Fang Q, Moore R, Kopans DB, Rafferty E, Boas DA. Dynamic functional and mechanical response of breast tissue to compression. Opt Express. 2008 Sep 29; 16(20):16064-78. PMID: 18825246.
    Citations: 20     Fields:    Translation:Humans
  66. Chan HP, Wei J, Zhang Y, Helvie MA, Moore RH, Sahiner B, Hadjiiski L, Kopans DB. Computer-aided detection of masses in digital tomosynthesis mammography: comparison of three approaches. Med Phys. 2008 Sep; 35(9):4087-95. PMID: 18841861.
    Citations: 21     Fields:    Translation:Humans
  67. Kopans DB. LCIS found at core needle biopsy may not need surgical excision. AJR Am J Roentgenol. 2008 Sep; 191(3):W152; author reply W153. PMID: 18716082.
    Citations: 2     Fields:    Translation:Humans
  68. Kopans DB, Pisano ED, Acharyya S, Hendrick RE, Yaffe MJ, Conant EF, Fajardo LL, Bassett LW, Baum JK, Gatsonis CA. DMIST results: technologic or observer variability? Radiology. 2008 Aug; 248(2):703; author reply 703. PMID: 18641262.
    Citations: 1     Fields:    Translation:HumansPHPublic Health
  69. Lee JM, Georgian-Smith D, Gazelle GS, Halpern EF, Rafferty EA, Moore RH, Yeh ED, D'Alessandro HA, Hitt RA, Kopans DB. Detecting nonpalpable recurrent breast cancer: the role of routine mammographic screening of transverse rectus abdominis myocutaneous flap reconstructions. Radiology. 2008 Aug; 248(2):398-405. PMID: 18539887.
    Citations: 2     Fields:    Translation:Humans
  70. Reiser I, Nishikawa RM, Edwards AV, Kopans DB, Schmidt RA, Papaioannou J, Moore RH. Automated detection of microcalcification clusters for digital breast tomosynthesis using projection data only: a preliminary study. Med Phys. 2008 Apr; 35(4):1486-93. PMID: 18491543.
    Citations: 16     Fields:    Translation:Humans
  71. Lee JM, Kopans DB, McMahon PM, Halpern EF, Ryan PD, Weinstein MC, Gazelle GS. Breast cancer screening in BRCA1 mutation carriers: effectiveness of MR imaging--Markov Monte Carlo decision analysis. Radiology. 2008 Mar; 246(3):763-71. PMID: 18309013.
    Citations: 16     Fields:    Translation:HumansPHPublic Health
  72. Kopans DB. History repeats. Radiology. 2008 Feb; 246(2):645; author reply 645-6. PMID: 18227558.
    Citations:    Fields:    Translation:HumansPHPublic Health
  73. Kopans DB. Basic physics and doubts about relationship between mammographically determined tissue density and breast cancer risk. Radiology. 2008 Feb; 246(2):348-53. PMID: 18227535.
    Citations: 57     Fields:    Translation:Humans
  74. Kopans DB. Screening mammography for women age 40 to 49 years. Ann Intern Med. 2007 Nov 20; 147(10):740-1; author reply 741. PMID: