Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Marie Demay, M.D.

Title
Institution
Department
Address
Phone
Fax

Research
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. P30AR075042 (KRONENBERG, HENRY M.) Jun 19, 2019 - May 31, 2024
    NIH/NIAMS
    Center for Skeletal Research (Overall Application)
    Role: Co-Principal Investigator
  2. R01AR073191 (LEDER, BENJAMIN Z) Apr 1, 2019 - Mar 31, 2023
    NIH/NIAMS
    Mechanisms Underlying the Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration
    Role: Co-Principal Investigator
  3. R21AR072351 (DEMAY, MARIE) Aug 10, 2018 - Jul 31, 2021
    NIH/NIAMS
    Optimizing Calcitriol Monotherapy for X-Linked Hypophosphatemia: Effects on Mineral Ions, Growth and Skeletal Parameters
    Role: Principal Investigator
  4. R01AR072650 (DEMAY, MARIE) Sep 21, 2017 - Aug 31, 2022
    NIH/NIAMS
    Hormonal and Molecular Etiology of Skeletal Abnormalities in XLH
    Role: Principal Investigator
  5. P30AR066261 (KRONENBERG, HENRY M.) Jun 1, 2014 - May 31, 2019
    NIH/NIAMS
    CENTER FOR SKELETAL RESEARCH
    Role: Co-Principal Investigator

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Noda H, Guo J, Khatri A, Dean T, Reyes M, Armanini M, Brooks DJ, Martins JS, Schipani E, Bouxsein ML, Demay MB, Potts JT, Jüppner H, Gardella TJ. An Inverse Agonist Ligand of the PTH Receptor Partially Rescues Skeletal Defects in a Mouse Model of Jansen's Metaphyseal Chondrodysplasia. J Bone Miner Res. 2020 Mar; 35(3):540-549. PMID: 31693237.
    Citations:    
  2. Martins JS, Liu ES, Sneddon WB, Friedman PA, Demay MB. 1,25-Dihydroxyvitamin D Maintains Brush Border Membrane NaPi2a and Attenuates Phosphaturia in Hyp Mice. Endocrinology. 2019 10 01; 160(10):2204-2214. PMID: 31237611.
    Citations:    
  3. Fleet JC, Campbell MJ, Carlberg C, Demay MB, Ebeling PR, Schoenmakers I, White JH, Welsh J, Hewison M. Highlights from the 21st Workshop on Vitamin D in Barcelona, May 2018. J Steroid Biochem Mol Biol. 2019 05; 189:210-217. PMID: 30926426.
    Citations:    
  4. Liu ES, Martins JS, Zhang W, Demay MB. Molecular analysis of enthesopathy in a mouse model of hypophosphatemic rickets. Development. 2018 08 10; 145(15). PMID: 30002128.
    Citations:    Fields:    Translation:AnimalsCells
  5. Demay MB. The good and the bad of vitamin D inactivation. J Clin Invest. 2018 08 31; 128(9):3736-3738. PMID: 30080183.
    Citations:    Fields:    
  6. Kuehn F, Adiliaghdam F, Hamarneh SR, Vasan R, Liu E, Liu Y, Ramirez JM, Hoda RS, Munoz AR, Ko FC, Armanini M, Brooks DJ, Bouxsein ML, Demay MB, Hodin RA. Loss of Intestinal Alkaline Phosphatase Leads to Distinct Chronic Changes in Bone Phenotype. J Surg Res. 2018 12; 232:325-331. PMID: 30463736.
    Citations:    Fields:    
  7. Liu ES, Thoonen R, Petit E, Yu B, Buys ES, Scherrer-Crosbie M, Demay MB. Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH. Endocrinology. 2018 05 01; 159(5):2165-2172. PMID: 29635291.
    Citations: 3     Fields:    Translation:Animals
  8. Engblom C, Pfirschke C, Zilionis R, Da Silva Martins J, Bos SA, Courties G, Rickelt S, Severe N, Baryawno N, Faget J, Savova V, Zemmour D, Kline J, Siwicki M, Garris C, Pucci F, Liao HW, Lin YJ, Newton A, Yaghi OK, Iwamoto Y, Tricot B, Wojtkiewicz GR, Nahrendorf M, Cortez-Retamozo V, Meylan E, Hynes RO, Demay M, Klein A, Bredella MA, Scadden DT, Weissleder R, Pittet MJ. Osteoblasts remotely supply lung tumors with cancer-promoting SiglecFhigh neutrophils. Science. 2017 12 01; 358(6367). PMID: 29191879.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  9. Hewison M, Fleet JC, Demay MB, Christakos S, Bouillon R, Welsh J, White JH. Highlights from the 20th Workshop on Vitamin D in Orlando, Mar. 28-31, 2017. J Steroid Biochem Mol Biol. 2018 03; 177:1-5. PMID: 29180166.
    Citations:    Fields:    
  10. Tokarz D, Martins JS, Petit ET, Lin CP, Demay MB, Liu ES. Hormonal Regulation of Osteocyte Perilacunar and Canalicular Remodeling in the Hyp Mouse Model of X-Linked Hypophosphatemia. J Bone Miner Res. 2018 03; 33(3):499-509. PMID: 29083055.
    Citations: 2     Fields:    
  11. Christakos S, White JH, Hewison M, Welsh J, Lips P, Bouillon R, Demay MB. Highlights from the 19th Workshop on Vitamin D in Boston, March 29-31, 2016. J Steroid Biochem Mol Biol. 2017 10; 173:1-4. PMID: 28895872.
    Citations:    Fields:    Translation:HumansAnimals
  12. Rolvien T, Krause M, Jeschke A, Yorgan T, Püschel K, Schinke T, Busse B, Demay MB, Amling M. Vitamin D regulates osteocyte survival and perilacunar remodeling in human and murine bone. Bone. 2017 Oct; 103:78-87. PMID: 28666969.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  13. Li Y, Caballero D, Ponsetto J, Chen A, Zhu C, Guo J, Demay M, Jüppner H, Bergwitz C. Response of Npt2a knockout mice to dietary calcium and phosphorus. PLoS One. 2017; 12(4):e0176232. PMID: 28448530.
    Citations: 1     Fields:    Translation:Animals
  14. Ko FC, Karim L, Brooks DJ, Bouxsein ML, Demay MB. Bisphosphonate Withdrawal: Effects on Bone Formation and Bone Resorption in Maturing Male Mice. J Bone Miner Res. 2017 04; 32(4):814-820. PMID: 27925290.
    Citations:    Fields:    Translation:AnimalsCells
  15. Papaioannou G, Petit ET, Liu ES, Baccarini M, Pritchard C, Demay MB. Raf Kinases Are Essential for Phosphate Induction of ERK1/2 Phosphorylation in Hypertrophic Chondrocytes and Normal Endochondral Bone Development. J Biol Chem. 2017 02 24; 292(8):3164-3171. PMID: 28073913.
    Citations:    Fields:    Translation:AnimalsCells
  16. Saini V, Zhao H, Petit ET, Gori F, Demay MB. Absence of vitamin D receptor (VDR)-mediated PPAR? suppression causes alopecia in VDR-null mice. FASEB J. 2017 03; 31(3):1059-1066. PMID: 27932380.
    Citations:    Fields:    Translation:AnimalsCells
  17. Dey D, Bagarova J, Hatsell SJ, Armstrong KA, Huang L, Ermann J, Vonner AJ, Shen Y, Mohedas AH, Lee A, Eekhoff EM, van Schie A, Demay MB, Keller C, Wagers AJ, Economides AN, Yu PB. Two tissue-resident progenitor lineages drive distinct phenotypes of heterotopic ossification. Sci Transl Med. 2016 11 23; 8(366):366ra163. PMID: 27881824.
    Citations: 15     Fields:    Translation:HumansAnimalsCells
  18. Ko FC, Martins JS, Reddy P, Bragdon B, Hussein AI, Gerstenfeld LC, Demay MB. Acute Phosphate Restriction Impairs Bone Formation and Increases Marrow Adipose Tissue in Growing Mice. J Bone Miner Res. 2016 12; 31(12):2204-2214. PMID: 27324177.
    Citations: 3     Fields:    Translation:AnimalsCells
  19. Lips P, Welsh J, Demay M, Bouillon R. Highlights from the 18th workshop on vitamin D, Delft, The Netherlands, April 21-24, 2015. J Steroid Biochem Mol Biol. 2016 11; 164:1-3. PMID: 27969101.
    Citations:    Fields:    Translation:Humans
  20. Song L, Papaioannou G, Zhao H, Luderer HF, Miller C, Dall'Osso C, Nazarian RM, Wagers AJ, Demay MB. The Vitamin D Receptor Regulates Tissue Resident Macrophage Response to Injury. Endocrinology. 2016 Oct; 157(10):4066-4075. PMID: 27526034.
    Citations: 4     Fields:    Translation:AnimalsCells
  21. Liu ES, Martins JS, Raimann A, Chae BT, Brooks DJ, Jorgetti V, Bouxsein ML, Demay MB. 1,25-Dihydroxyvitamin D Alone Improves Skeletal Growth, Microarchitecture, and Strength in a Murine Model of XLH, Despite Enhanced FGF23 Expression. J Bone Miner Res. 2016 05; 31(5):929-39. PMID: 26751835.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  22. Liu ES, Raimann A, Chae BT, Martins JS, Baccarini M, Demay MB. c-Raf promotes angiogenesis during normal growth plate maturation. Development. 2016 Jan 15; 143(2):348-55. PMID: 26657770.
    Citations: 3     Fields:    Translation:AnimalsCells
  23. Lisse TS, Saini V, Zhao H, Luderer HF, Gori F, Demay MB. The vitamin D receptor is required for activation of cWnt and hedgehog signaling in keratinocytes. Mol Endocrinol. 2014 Oct; 28(10):1698-706. PMID: 25180455.
    Citations: 8     Fields:    Translation:AnimalsCells
  24. Liu ES, Zalutskaya A, Chae BT, Zhu ED, Gori F, Demay MB. Phosphate interacts with PTHrP to regulate endochondral bone formation. Endocrinology. 2014 Oct; 155(10):3750-6. PMID: 25057796.
    Citations: 2     Fields:    Translation:AnimalsCells
  25. Zhu ED, Louis L, Brooks DJ, Bouxsein ML, Demay MB. Effect of bisphosphonates on the rapidly growing male murine skeleton. Endocrinology. 2014 Apr; 155(4):1188-96. PMID: 24422540.
    Citations: 6     Fields:    Translation:AnimalsCells
  26. Luderer HF, Nazarian RM, Zhu ED, Demay MB. Ligand-dependent actions of the vitamin D receptor are required for activation of TGF-ß signaling during the inflammatory response to cutaneous injury. Endocrinology. 2013 Jan; 154(1):16-24. PMID: 23132743.
    Citations: 15     Fields:    Translation:AnimalsCells
  27. Demay MB. Physiological insights from the vitamin D receptor knockout mouse. Calcif Tissue Int. 2013 Feb; 92(2):99-105. PMID: 22903507.
    Citations: 4     Fields:    Translation:HumansAnimals
  28. Rosen CJ, Adams JS, Bikle DD, Black DM, Demay MB, Manson JE, Murad MH, Kovacs CS. The nonskeletal effects of vitamin D: an Endocrine Society scientific statement. Endocr Rev. 2012 Jun; 33(3):456-92. PMID: 22596255.
    Citations: 142     Fields:    Translation:HumansAnimals
  29. Demay MB. The hair cycle and Vitamin D receptor. Arch Biochem Biophys. 2012 Jul 01; 523(1):19-21. PMID: 22008469.
    Citations: 9     Fields:    Translation:HumansAnimals
  30. Luderer HF, Gori F, Demay MB. Lymphoid enhancer-binding factor-1 (LEF1) interacts with the DNA-binding domain of the vitamin D receptor. J Biol Chem. 2011 May 27; 286(21):18444-51. PMID: 21471213.
    Citations: 18     Fields:    Translation:HumansAnimalsCells
  31. Bell TD, Demay MB, Burnett-Bowie SA. The biology and pathology of vitamin D control in bone. J Cell Biochem. 2010 Sep 01; 111(1):7-13. PMID: 20506379.
    Citations: 16     Fields:    Translation:HumansAnimals
  32. Miedlich SU, Zhu ED, Sabbagh Y, Demay MB. The receptor-dependent actions of 1,25-dihydroxyvitamin D are required for normal growth plate maturation in NPt2a knockout mice. Endocrinology. 2010 Oct; 151(10):4607-12. PMID: 20685875.
    Citations: 10     Fields:    Translation:Animals
  33. Miedlich SU, Zalutskaya A, Zhu ED, Demay MB. Phosphate-induced apoptosis of hypertrophic chondrocytes is associated with a decrease in mitochondrial membrane potential and is dependent upon Erk1/2 phosphorylation. J Biol Chem. 2010 Jun 11; 285(24):18270-5. PMID: 20404333.
    Citations: 21     Fields:    Translation:AnimalsCells
  34. Wigner NA, Luderer HF, Cox MK, Sooy K, Gerstenfeld LC, Demay MB. Acute phosphate restriction leads to impaired fracture healing and resistance to BMP-2. J Bone Miner Res. 2010 Apr; 25(4):724-33. PMID: 19839770.
    Citations: 7     Fields:    Translation:AnimalsCells
  35. Luderer HF, Demay MB. The vitamin D receptor, the skin and stem cells. J Steroid Biochem Mol Biol. 2010 Jul; 121(1-2):314-6. PMID: 20138991.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  36. Zalutskaya AA, Cox MK, Demay MB. Phosphate regulates embryonic endochondral bone development. J Cell Biochem. 2009 Oct 15; 108(3):668-74. PMID: 19681042.
    Citations: 6     Fields:    Translation:AnimalsCells
  37. Gori F, Zhu ED, Demay MB. Perichondrial expression of Wdr5 regulates chondrocyte proliferation and differentiation. Dev Biol. 2009 May 01; 329(1):36-43. PMID: 19217897.
    Citations: 4     Fields:    Translation:AnimalsCells
  38. Gutierrez GM, Kong E, Sabbagh Y, Brown NE, Lee JS, Demay MB, Thomas DM, Hinds PW. Impaired bone development and increased mesenchymal progenitor cells in calvaria of RB1-/- mice. Proc Natl Acad Sci U S A. 2008 Nov 25; 105(47):18402-7. PMID: 19020086.
    Citations: 33     Fields:    Translation:AnimalsCells
  39. Bouillon R, Carmeliet G, Verlinden L, van Etten E, Verstuyf A, Luderer HF, Lieben L, Mathieu C, Demay M. Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev. 2008 Oct; 29(6):726-76. PMID: 18694980.
    Citations: 319     Fields:    Translation:HumansAnimals
  40. Demay MB, Rosenthal DI, Deshpande V. Case records of the Massachusetts General Hospital. Case 16-2008. A 46-year-old woman with bone pain. N Engl J Med. 2008 May 22; 358(21):2266-74. PMID: 18499570.
    Citations: 3     Fields:    Translation:Humans
  41. Zhu ED, Demay MB, Gori F. Wdr5 is essential for osteoblast differentiation. J Biol Chem. 2008 Mar 21; 283(12):7361-7. PMID: 18201971.
    Citations: 21     Fields:    Translation:AnimalsCells
  42. Cianferotti L, Cox M, Skorija K, Demay MB. Vitamin D receptor is essential for normal keratinocyte stem cell function. Proc Natl Acad Sci U S A. 2007 May 29; 104(22):9428-33. PMID: 17517646.
    Citations: 50     Fields:    Translation:AnimalsCells
  43. Cianferotti L, Demay MB. VDR-mediated inhibition of DKK1 and SFRP2 suppresses adipogenic differentiation of murine bone marrow stromal cells. J Cell Biochem. 2007 May 01; 101(1):80-8. PMID: 17212358.
    Citations: 15     Fields:    Translation:AnimalsCells
  44. Demay MB, Sabbagh Y, Carpenter TO. Calcium and vitamin D: what is known about the effects on growing bone. Pediatrics. 2007 Mar; 119 Suppl 2:S141-4. PMID: 17332234.
    Citations: 10     Fields:    Translation:AnimalsCells
  45. Demay MB, MacDonald PN, Skorija K, Dowd DR, Cianferotti L, Cox M. Role of the vitamin D receptor in hair follicle biology. J Steroid Biochem Mol Biol. 2007 Mar; 103(3-5):344-6. PMID: 17223342.
    Citations: 12     Fields:    Translation:HumansAnimals
  46. Gori F, Friedman LG, Demay MB. Wdr5, a WD-40 protein, regulates osteoblast differentiation during embryonic bone development. Dev Biol. 2006 Jul 15; 295(2):498-506. PMID: 16730692.
    Citations: 18     Fields:    Translation:AnimalsCells
  47. Demay MB. Mechanism of vitamin D receptor action. Ann N Y Acad Sci. 2006 Apr; 1068:204-13. PMID: 16831920.
    Citations: 31     Fields:    Translation:HumansAnimals
  48. Gori F, Friedman L, Demay MB. Wdr5, a novel WD repeat protein, regulates osteoblast and chondrocyte differentiation in vivo. J Musculoskelet Neuronal Interact. 2005 Oct-Dec; 5(4):338-9. PMID: 16340128.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  49. Sabbagh Y, Carpenter TO, Demay MB. Hypophosphatemia leads to rickets by impairing caspase-mediated apoptosis of hypertrophic chondrocytes. Proc Natl Acad Sci U S A. 2005 Jul 05; 102(27):9637-42. PMID: 15976027.
    Citations: 56     Fields:    Translation:AnimalsCells
  50. Yu X, Sabbagh Y, Davis SI, Demay MB, White KE. Genetic dissection of phosphate- and vitamin D-mediated regulation of circulating Fgf23 concentrations. Bone. 2005 Jun; 36(6):971-7. PMID: 15869926.
    Citations: 48     Fields:    Translation:Animals
  51. Sooy K, Sabbagh Y, Demay MB. Osteoblasts lacking the vitamin D receptor display enhanced osteogenic potential in vitro. J Cell Biochem. 2005 Jan 01; 94(1):81-7. PMID: 15517598.
    Citations: 17     Fields:    Translation:AnimalsCells
  52. Gori F, Demay MB. The effects of BIG-3 on osteoblast differentiation are not dependent upon endogenously produced BMPs. Exp Cell Res. 2005 Mar 10; 304(1):287-92. PMID: 15707593.
    Citations:    Fields:    Translation:AnimalsCells
  53. Skorija K, Cox M, Sisk JM, Dowd DR, MacDonald PN, Thompson CC, Demay MB. Ligand-independent actions of the vitamin D receptor maintain hair follicle homeostasis. Mol Endocrinol. 2005 Apr; 19(4):855-62. PMID: 15591533.
    Citations: 44     Fields:    Translation:AnimalsCells
  54. Masuda S, Byford V, Arabian A, Sakai Y, Demay MB, St-Arnaud R, Jones G. Altered pharmacokinetics of 1alpha,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D-24-hydroxylase (Cyp24a1) null mouse. Endocrinology. 2005 Feb; 146(2):825-34. PMID: 15498883.
    Citations: 31     Fields:    Translation:AnimalsCells
  55. Gori F, Demay MB. BIG-3, a novel WD-40 repeat protein, is expressed in the developing growth plate and accelerates chondrocyte differentiation in vitro. Endocrinology. 2004 Mar; 145(3):1050-4. PMID: 14657013.
    Citations: 8     Fields:    Translation:AnimalsCells
  56. Demay M. Muscle: a nontraditional 1,25-dihydroxyvitamin D target tissue exhibiting classic hormone-dependent vitamin D receptor actions. Endocrinology. 2003 Dec; 144(12):5135-7. PMID: 14645209.
    Citations: 6     Fields:    Translation:HumansAnimals
  57. Sooy K, Demay MB. Transcriptional repression of the rat osteocalcin gene by deltaEF1. Endocrinology. 2002 Sep; 143(9):3370-5. PMID: 12193549.
    Citations: 6     Fields:    Translation:AnimalsCells
  58. Donohue MM, Demay MB. Rickets in VDR null mice is secondary to decreased apoptosis of hypertrophic chondrocytes. Endocrinology. 2002 Sep; 143(9):3691-4. PMID: 12193585.
    Citations: 24     Fields:    Translation:AnimalsCells
  59. Chen CH, Sakai Y, Demay MB. Targeting expression of the human vitamin D receptor to the keratinocytes of vitamin D receptor null mice prevents alopecia. Endocrinology. 2001 Dec; 142(12):5386-9. PMID: 11713240.
    Citations: 27     Fields:    Translation:HumansAnimalsCells
  60. Gori F, Divieti P, Demay MB. Cloning and characterization of a novel WD-40 repeat protein that dramatically accelerates osteoblastic differentiation. J Biol Chem. 2001 Dec 07; 276(49):46515-22. PMID: 11551928.
    Citations: 19     Fields:    Translation:AnimalsCells
  61. Kearns AE, Donohue MM, Sanyal B, Demay MB. Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro. J Biol Chem. 2001 Nov 09; 276(45):42213-8. PMID: 11500515.
    Citations: 16     Fields:    Translation:AnimalsCells
  62. Sakai Y, Kishimoto J, Demay MB. Metabolic and cellular analysis of alopecia in vitamin D receptor knockout mice. J Clin Invest. 2001 Apr; 107(8):961-6. PMID: 11306599.
    Citations: 29     Fields:    Translation:AnimalsCells
  63. Gori F, Schipani E, Demay MB. Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27; 82(1):46-57. PMID: 11400162.
    Citations: 6     Fields:    Translation:AnimalsCells
  64. Merscher S, Funke B, Epstein JA, Heyer J, Puech A, Lu MM, Xavier RJ, Demay MB, Russell RG, Factor S, Tokooya K, Jore BS, Lopez M, Pandita RK, Lia M, Carrion D, Xu H, Schorle H, Kobler JB, Scambler P, Wynshaw-Boris A, Skoultchi AI, Morrow BE, Kucherlapati R. TBX1 is responsible for cardiovascular defects in velo-cardio-facial/DiGeorge syndrome. Cell. 2001 Feb 23; 104(4):619-29. PMID: 11239417.
    Citations: 242     Fields:    Translation:HumansAnimalsCells
  65. Thomas MK, Demay MB. Vitamin D deficiency and disorders of vitamin D metabolism. Endocrinol Metab Clin North Am. 2000 Sep; 29(3):611-27, viii. PMID: 11033763.
    Citations: 16     Fields:    Translation:Humans
  66. Kearns AE, Demay MB. BMP-2 induces the expression of activin betaA and follistatin in vitro. J Cell Biochem. 2000 Jul 19; 79(1):80-8. PMID: 10906757.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  67. St-Arnaud R, Arabian A, Travers R, Barletta F, Raval-Pandya M, Chapin K, Depovere J, Mathieu C, Christakos S, Demay MB, Glorieux FH. Deficient mineralization of intramembranous bone in vitamin D-24-hydroxylase-ablated mice is due to elevated 1,25-dihydroxyvitamin D and not to the absence of 24,25-dihydroxyvitamin D. Endocrinology. 2000 Jul; 141(7):2658-66. PMID: 10875271.
    Citations: 57     Fields:    Translation:Animals
  68. Sakai Y, Demay MB. Evaluation of keratinocyte proliferation and differentiation in vitamin D receptor knockout mice. Endocrinology. 2000 Jun; 141(6):2043-9. PMID: 10830288.
    Citations: 26     Fields:    Translation:AnimalsCells
  69. Amling M, Priemel M, Holzmann T, Chapin K, Rueger JM, Baron R, Demay MB. Rescue of the skeletal phenotype of vitamin D receptor-ablated mice in the setting of normal mineral ion homeostasis: formal histomorphometric and biomechanical analyses. Endocrinology. 1999 Nov; 140(11):4982-7. PMID: 10537122.
    Citations: 103     Fields:    Translation:AnimalsCells
  70. Amling M, Priemel M, Holzmann T, Chapin K, Rueger JM, Baron R, Demay MB. Rescue of the Skeletal Phenotype of Vitamin D Receptor-Ablated Mice in the Setting of Normal Mineral Ion Homeostasis: Formal Histomorphometric and Biomechanical Analyses1. Endocrinology. 1999 Nov 01; 140(11):4982-4987. PMID: 28200431.
    Citations:    
  71. Kearns AE, Goto K, Gianakakos G, Lippmann W, Demay MB. Transcriptional repression of the rat osteocalcin gene: role of two intronic CCTCCT motifs. Endocrinology. 1999 Sep; 140(9):4120-6. PMID: 10465284.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  72. Kearns AE, Goto K, Gianakakos G, Lippmann W, Demay MB. Transcriptional Repression of the Rat Osteocalcin Gene: Role of Two Intronic CCTCCT Motifs1. Endocrinology. 1999 Sep 01; 140(9):4120-4126. PMID: 28200814.
    Citations:    
  73. Sneddon WB, Demay MB. Characterization of an enhancer required for 1,25-dihydroxyvitamin D3-dependent transactivation of the rat osteocalcin gene. J Cell Biochem. 1999 Jun 01; 73(3):400-7. PMID: 10321839.
    Citations:    Fields:    Translation:AnimalsCells
  74. Li YC, Amling M, Pirro AE, Priemel M, Meuse J, Baron R, Delling G, Demay MB. Normalization of Mineral Ion Homeostasis by Dietary Means Prevents Hyperparathyroidism, Rickets, and Osteomalacia, But Not Alopecia in Vitamin D Receptor-Ablated Mice* * This work was supported by NIH Grants DK-46974 (to M.B.D.) and DE-04724 (to R.B.) and a NIH National Research Service Award (to Y.C.L.). Endocrinology. 1998 Oct 01; 139(10):4391-4396. PMID: 28200198.
    Citations:    
  75. Li YC, Amling M, Pirro AE, Priemel M, Meuse J, Baron R, Delling G, Demay MB. Normalization of mineral ion homeostasis by dietary means prevents hyperparathyroidism, rickets, and osteomalacia, but not alopecia in vitamin D receptor-ablated mice. Endocrinology. 1998 Oct; 139(10):4391-6. PMID: 9751523.
    Citations: 99     Fields:    Translation:Animals
  76. Li YC, Pirro AE, Demay MB. Analysis of vitamin D-dependent calcium-binding protein messenger ribonucleic acid expression in mice lacking the vitamin D receptor. Endocrinology. 1998 Mar; 139(3):847-51. PMID: 9492012.
    Citations: 10     Fields:    Translation:Animals
  77. Li YC, Pirro AE, Amling M, Delling G, Baron R, Bronson R, Demay MB. Targeted ablation of the vitamin D receptor: an animal model of vitamin D-dependent rickets type II with alopecia. Proc Natl Acad Sci U S A. 1997 Sep 02; 94(18):9831-5. PMID: 9275211.
    Citations: 201     Fields:    Translation:AnimalsCells
  78. Li YC, Bergwitz C, Jüppner H, Demay MB. Cloning and characterization of the vitamin D receptor from Xenopus laevis. Endocrinology. 1997 Jun; 138(6):2347-53. PMID: 9165021.
    Citations: 13     Fields:    Translation:HumansAnimalsCells
  79. Li YC, Bergwitz C, Ju Ppner H, Demay MB. Cloning and Characterization of the Vitamin D Receptor from Xenopus laevis. Endocrinology. 1997 Jun 01; 138(6):2347-2353. PMID: 28199616.
    Citations:    
  80. Sneddon WB, Bogado CE, Kiernan MS, Demay MB. DNA sequences downstream from the vitamin D response element of the rat osteocalcin gene are required for ligand-dependent transactivation. Mol Endocrinol. 1997 Feb; 11(2):210-7. PMID: 9013768.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  81. Goto K, Heymont JL, Klein-Nulend J, Kronenberg HM, Demay MB. Identification of an osteoblastic silencer element in the first intron of the rat osteocalcin gene. Biochemistry. 1996 Aug 20; 35(33):11005-11. PMID: 8718894.
    Citations: 3     Fields:    Translation:AnimalsCells
  82. Mackey SL, Heymont JL, Kronenberg HM, Demay MB. Vitamin D receptor binding to the negative human parathyroid hormone vitamin D response element does not require the retinoid x receptor. Mol Endocrinol. 1996 Mar; 10(3):298-305. PMID: 8833658.
    Citations: 7     Fields:    Translation:HumansAnimalsCells
  83. Nanes MS, Kuno H, Demay MB, Kurian M, Hendy GN, DeLuca HF, Titus L, Rubin J. A single up-stream element confers responsiveness to 1,25-dihydroxyvitamin D3 and tumor necrosis factor-alpha in the rat osteocalcin gene. Endocrinology. 1994 Mar; 134(3):1113-20. PMID: 8119149.
    Citations: 2     Fields:    Translation:AnimalsCells
  84. Demay MB, Kiernan MS, DeLuca HF, Kronenberg HM. Sequences in the human parathyroid hormone gene that bind the 1,25-dihydroxyvitamin D3 receptor and mediate transcriptional repression in response to 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A. 1992 Sep 01; 89(17):8097-101. PMID: 1325645.
    Citations: 49     Fields:    Translation:HumansAnimalsCells
  85. Demay MB, Kiernan MS, DeLuca HF, Kronenberg HM. Characterization of 1,25-dihydroxyvitamin D3 receptor interactions with target sequences in the rat osteocalcin gene. Mol Endocrinol. 1992 Apr; 6(4):557-62. PMID: 1316548.
    Citations: 9     Fields:    Translation:AnimalsCells
  86. Demay MB, Gerardi JM, DeLuca HF, Kronenberg HM. DNA sequences in the rat osteocalcin gene that bind the 1,25-dihydroxyvitamin D3 receptor and confer responsiveness to 1,25-dihydroxyvitamin D3. Proc Natl Acad Sci U S A. 1990 Jan; 87(1):369-73. PMID: 2153298.
    Citations: 48     Fields:    Translation:AnimalsCells
  87. Demay MB, Roth DA, Kronenberg HM. Regions of the rat osteocalcin gene which mediate the effect of 1,25-dihydroxyvitamin D3 on gene transcription. J Biol Chem. 1989 Feb 05; 264(4):2279-82. PMID: 2783691.
    Citations: 16     Fields:    Translation:AnimalsCells
  88. Khosla S, Demay M, Pines M, Hurwitz S, Potts JT, Kronenberg HM. Nucleotide sequence of cloned cDNAs encoding chicken preproparathyroid hormone. J Bone Miner Res. 1988 Dec; 3(6):689-98. PMID: 3251402.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  89. Demay M, Mitchell J, Goltzman D. Comparison of renal and osseous binding of parathyroid hormone and hormonal fragments. Am J Physiol. 1985 Nov; 249(5 Pt 1):E437-46. PMID: 3864382.
    Citations: 4     Fields:    Translation:AnimalsCells
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Demay's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (352)
Explore
_
Co-Authors (39)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Physical Neighbors
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.