Harvard Catalyst Profiles

Contact, publication, and social network information about Harvard faculty and fellows.

Kevin Hodgetts, Ph.D.

Title
Institution
Department
Address

Bibliographic
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Foster JB, Lashley R, Zhao F, Wang X, Kung N, Askwith CC, Lin L, Shultis MW, Hodgetts KJ, Lin CG. Enhancement of tripartite synapses as a potential therapeutic strategy for Alzheimer's disease: a preclinical study in rTg4510 mice. Alzheimers Res Ther. 2019 08 23; 11(1):75. PMID: 31439023.
    Citations:    
  2. Osman EY, Rietz A, Kline RA, Cherry JJ, Hodgetts KJ, Lorson CL, Androphy EJ. Intraperitoneal delivery of a novel drug-like compound improves disease severity in severe and intermediate mouse models of Spinal Muscular Atrophy. Sci Rep. 2019 02 07; 9(1):1633. PMID: 30733501.
    Citations:    
  3. Foster JB, Zhao F, Wang X, Xu Z, Lin K, Askwith CC, Hodgetts KJ, Lin CG. Pyridazine-derivatives Enhance Structural and Functional Plasticity of Tripartite Synapse Via Activation of Local Translation in Astrocytic Processes. Neuroscience. 2018 09 15; 388:224-238. PMID: 30056115.
    Citations:    Fields:    
  4. Choi S, Calder AN, Miller EH, Anderson KP, Fiejtek DK, Rietz A, Li H, Cherry JJ, Quist KM, Xing X, Glicksman MA, Cuny GD, Lorson CL, Androphy EA, Hodgetts KJ. Optimization of a series of heterocycles as survival motor neuron gene transcription enhancers. Bioorg Med Chem Lett. 2017 12 01; 27(23):5144-5148. PMID: 29103974.
    Citations:    Fields:    Translation:HumansAnimalsCells
  5. Rietz A, Li H, Quist KM, Cherry JJ, Lorson CL, Burnett BG, Kern NL, Calder AN, Fritsche M, Lusic H, Boaler PJ, Choi S, Xing X, Glicksman MA, Cuny GD, Androphy EJ, Hodgetts KJ. Discovery of a Small Molecule Probe That Post-Translationally Stabilizes the Survival Motor Neuron Protein for the Treatment of Spinal Muscular Atrophy. J Med Chem. 2017 06 08; 60(11):4594-4610. PMID: 28481536.
    Citations: 1     Fields:    Translation:HumansCells
  6. Calder AN, Androphy EJ, Hodgetts KJ. Small Molecules in Development for the Treatment of Spinal Muscular Atrophy. J Med Chem. 2016 11 23; 59(22):10067-10083. PMID: 27490705.
    Citations: 10     Fields:    Translation:HumansCells
  7. Takahashi K, Kong Q, Lin Y, Stouffer N, Schulte DA, Lai L, Liu Q, Chang LC, Dominguez S, Xing X, Cuny GD, Hodgetts KJ, Glicksman MA, Lin CL. Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer's disease. J Exp Med. 2015 Mar 09; 212(3):319-32. PMID: 25711212.
    Citations: 13     Fields:    Translation:AnimalsCells
  8. Hodgetts KJ, Ge P, Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Kieltyka A, Horvath RF, Kehne JH, Krause JE, Maynard GD, Hoffman D, Lee Y, Fung L, Doller D. Discovery of N-(1-ethylpropyl)-[3-methoxy-5-(2-methoxy-4-trifluoromethoxyphenyl)-6-methyl-pyrazin-2-yl]amine 59 (NGD 98-2): an orally active corticotropin releasing factor-1 (CRF-1) receptor antagonist. J Med Chem. 2011 Jun 23; 54(12):4187-206. PMID: 21618986.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  9. Hodgetts KJ, Blum CA, Caldwell T, Bakthavatchalam R, Zheng X, Capitosti S, Krause JE, Cortright D, Crandall M, Murphy BA, Boyce S, Brian Jones A, Chenard BL. Pyrido[2,3-b]pyrazines, discovery of TRPV1 antagonists with reduced potential for the formation of reactive metabolites. Bioorg Med Chem Lett. 2010 Aug 01; 20(15):4359-63. PMID: 20615696.
    Citations:    Fields:    Translation:HumansAnimalsCells
  10. Blum CA, Caldwell T, Zheng X, Bakthavatchalam R, Capitosti S, Brielmann H, De Lombaert S, Kershaw MT, Matson D, Krause JE, Cortright D, Crandall M, Martin WJ, Murphy BA, Boyce S, Jones AB, Mason G, Rycroft W, Perrett H, Conley R, Burnaby-Davies N, Chenard BL, Hodgetts KJ. Discovery of novel 6,6-heterocycles as transient receptor potential vanilloid (TRPV1) antagonists. J Med Chem. 2010 Apr 22; 53(8):3330-48. PMID: 20307063.
    Citations: 3     Fields:    Translation:HumansAnimalsCells
  11. Guo Q, Chandrasekhar J, Ihle D, Wustrow DJ, Chenard BL, Krause JE, Hutchison A, Alderman D, Cheng C, Cortright D, Broom D, Kershaw MT, Simmermacher-Mayer J, Peng Y, Hodgetts KJ. 1-Benzylbenzimidazoles: the discovery of a novel series of bradykinin B(1) receptor antagonists. Bioorg Med Chem Lett. 2008 Sep 15; 18(18):5027-31. PMID: 18752949.
    Citations:    Fields:    Translation:AnimalsCells
  12. Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Krause JE, Hutchison A, Horvath RF, Ge P, Kehne J, Hoffman D, Chandrasekhar J, Doller D, Hodgetts KJ. 2-Arylpyrimidines: novel CRF-1 receptor antagonists. Bioorg Med Chem Lett. 2008 Aug 15; 18(16):4486-90. PMID: 18672365.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  13. Blum CA, Zheng X, Brielmann H, Hodgetts KJ, Bakthavatchalam R, Chandrasekhar J, Krause JE, Cortright D, Matson D, Crandall M, Ngo CK, Fung L, Day M, Kershaw M, De Lombaert S, Chenard BL. Aminoquinazolines as TRPV1 antagonists: modulation of drug-like properties through the exploration of 2-position substitution. Bioorg Med Chem Lett. 2008 Aug 15; 18(16):4573-7. PMID: 18662872.
    Citations: 1     Fields:    Translation:AnimalsCells
  14. Yoon T, De Lombaert S, Brodbeck R, Gulianello M, Chandrasekhar J, Horvath RF, Ge P, Kershaw MT, Krause JE, Kehne J, Hoffman D, Doller D, Hodgetts KJ. The design, synthesis and structure-activity relationships of 1-aryl-4-aminoalkylisoquinolines: a novel series of CRF-1 receptor antagonists. Bioorg Med Chem Lett. 2008 Feb 01; 18(3):891-6. PMID: 18180159.
    Citations: 3     Fields:    Translation:HumansCells
  15. Zheng X, Hodgetts KJ, Brielmann H, Hutchison A, Burkamp F, Brian Jones A, Blurton P, Clarkson R, Chandrasekhar J, Bakthavatchalam R, De Lombaert S, Crandall M, Cortright D, Blum CA. From arylureas to biarylamides to aminoquinazolines: discovery of a novel, potent TRPV1 antagonist. Bioorg Med Chem Lett. 2006 Oct 01; 16(19):5217-21. PMID: 16870426.
    Citations: 4     Fields:    Translation:HumansAnimalsCells
  16. Hodgetts KJ, Kershaw MT. Synthesis of 2-aryl-oxazolo[4,5-c]quinoline-4(5H)-ones and 2-aryl-thiazolo[4,5-c]quinoline-4(5H)-ones. Org Lett. 2003 Aug 07; 5(16):2911-4. PMID: 12889906.
    Citations: 1     Fields:    
  17. Hodgetts KJ, Yoon T, Huang J, Gulianello M, Kieltyka A, Primus R, Brodbeck R, De Lombaert S, Doller D. 2-Aryl-3,6-dialkyl-5-dialkylaminopyrimidin-4-ones as novel crf-1 receptor antagonists. Bioorg Med Chem Lett. 2003 Aug 04; 13(15):2497-500. PMID: 12852951.
    Citations: 1     Fields:    Translation:HumansCells
  18. Zhao H, Zhang X, Hodgetts K, Thurkauf A, Hammer J, Chandrasekhar J, Kieltyka A, Brodbeck R, Rachwal S, Primus R, Manly C. Design, synthesis, and discovery of 5-piperazinyl-1,2,6,7-tetrahydro-5H-azepino[3,2,1-hi]indol-4-one derivatives: a novel series of mixed dopamine D2/D4 receptor antagonist. Bioorg Med Chem Lett. 2003 Feb 24; 13(4):701-4. PMID: 12639562.
    Citations:    Fields:    Translation:HumansCells
  19. Zhao H, Thurkauf A, He X, Hodgetts K, Zhang X, Rachwal S, Kover RX, Hutchison A, Peterson J, Kieltyka A, Brodbeck R, Primus R, Wasley JW. Indoline and piperazine containing derivatives as a novel class of mixed D(2)/D(4) receptor antagonists. Part 1: identification and structure-activity relationships. Bioorg Med Chem Lett. 2002 Nov 04; 12(21):3105-9. PMID: 12372512.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  20. Hodgetts KJ, Kershaw MT. Ethyl 2-chlorooxazole-4-carboxylate: a versatile intermediate for the synthesis of substituted oxazoles. Org Lett. 2002 Aug 22; 4(17):2905-7. PMID: 12182585.
    Citations: 5     Fields:    
  21. Yuan J, Gulianello M, De Lombaert S, Brodbeck R, Kieltyka A, Hodgetts KJ. 3-Aryl pyrazolo[4,3-d]pyrimidine derivatives: Nonpeptide CRF-1 antagonists. Bioorg Med Chem Lett. 2002 Aug 19; 12(16):2133-6. PMID: 12127521.
    Citations: 2     Fields:    Translation:Cells
  22. Hodgetts KJ, Kershaw MT. Regiocontrolled synthesis of substituted thiazoles. Org Lett. 2002 Apr 18; 4(8):1363-5. PMID: 11950363.
    Citations: 1     Fields:    Translation:Cells
  23. Hodgetts KJ, Kieltyka A, Brodbeck R, Tran JN, Wasley JW, Thurkauf A. 6-(4-Benzylpiperazin-1-yl)benzodioxanes as selective ligands at cloned primate dopamine D(4) receptors. Bioorg Med Chem. 2001 Dec; 9(12):3207-13. PMID: 11711296.
    Citations: 2     Fields:    Translation:AnimalsCells
  24. Zhang X, Hodgetts K, Rachwal S, Zhao H, Wasley JW, Craven K, Brodbeck R, Kieltyka A, Hoffman D, Bacolod MD, Girard B, Tran J, Thurkauf A. trans-1-[(2-Phenylcyclopropyl)methyl]-4-arylpiperazines: mixed dopamine D(2)/D(4) receptor antagonists as potential antipsychotic agents. J Med Chem. 2000 Oct 19; 43(21):3923-32. PMID: 11052797.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  25. Bolitho DG, Boustred M, Hudson DA, Hodgetts K. Primary epineural repair of the ulnar nerve in children. J Hand Surg Am. 1999 Jan; 24(1):16-20. PMID: 10048511.
    Citations: 6     Fields:    Translation:Humans
  26. Hudson DA, Bolitho DG, Hodgetts K. Primary epineural repair of the median nerve in children. J Hand Surg Br. 1997 Feb; 22(1):54-6. PMID: 9061526.
    Citations: 3     Fields:    Translation:Humans
Local representatives can answer questions about the Profiles website or help with editing a profile or issues with profile data. For assistance with this profile: HMS/HSDM faculty should contact feedbackcatalyst.harvard.edu. For faculty or fellow appointment updates and changes, please ask your appointing department to contact HMS. For fellow personal and demographic information, contact HMS Human Resources at human_resourceshms.harvard.edu. For faculty personal and demographic information, contact HMS Office for Faculty Affairs at facappthms.harvard.edu.
Hodgetts's Networks
Click the
Explore
buttons for more information and interactive visualizations!
Concepts (147)
Explore
_
Similar People (60)
Explore
_
Same Department 
Explore
_
Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.