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Clapham, David
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David Clapham, M.D., Ph.D.
Title
Aldo R. Castaneda Professor of Cardiovascular Research, Emeritus
Institution
Harvard Medical School
Department
Emeritus
Address
Children's Hospital
Enders 1309
320 Longwood Ave
Boston MA 02115
Phone
617/872-7922
Fax
617/731-0787
vCard
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completed student projects
|
research activities and funding
|
selected publications
|
Mentoring
completed student projects
External Calcium Modulates TRPC5 Activity
Summer, 06/20/05 - 08/15/05
A Study of Transient Receptor Channels (trp) in C Elegans
Summer, 05/20/99 - 09/01/99
Characterization of human STIM and Orai, putative regulators of cytosolic calcium signaling
Full Time, 09/15/06 - 03/30/07
Research
research activities and funding
The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can
login
to make corrections and additions.
Most Recent
|
List All
R56DK103739
(CLAPHAM, DAVID E.)
Sep 1, 2015 - Aug 31, 2016
NIH/NIDDK
Direct measurement of polycystin channels and their regulation in cilia
Role: Principal Investigator
R01MH105851
(BOLSHAKOV, VADIM)
Jul 1, 2015 - Mar 31, 2021
NIH
TRPC-mediated control of anxiety
Role: Co-Principal Investigator
P01NS072040
(CLAPHAM, DAVID E.)
Aug 1, 2011 - May 31, 2017
NIH
TRP Channel Mediated Pain Circuitry
Role: Co-Principal Investigator
R01MH090293
(CLAPHAM, DAVID E.)
Mar 15, 2010 - Dec 31, 2014
NIH/NIMH
Canonical Transient Receptor Potential (TRPC) subfamily function in Hippocampus.
Role: Principal Investigator
U01HD045857
(CLAPHAM, DAVID E.)
Jan 30, 2004 - Jan 31, 2014
NIH/NICHD
CarSpers:sperm-specific ion channels;targets for male contraceptives
Role: Principal Investigator
R01HD045339
(CLAPHAM, DAVID E.)
Jan 1, 2004 - Dec 31, 2009
NIH/NICHD
Novel CatSper3 and CatSper4 Ion Channel Genes in Sperm
Role: Principal Investigator
R01GM068658
(CLAPHAM, DAVID E.)
Jul 1, 2003 - Jun 30, 2008
NIH/NIGMS
Structure and Function of a Bacterial Na Channel
Role: Principal Investigator
R13NS037978
(CLAPHAM, DAVID E.)
Jul 5, 1998 - Jun 30, 1999
NIH/NINDS
ION CHANNELS
Role: Principal Investigator
R13ES008963
(CLAPHAM, DAVID E.)
Sep 1, 1997 - Nov 30, 1997
NIH/NIEHS
1997 CALCIUM SIGNALING GORDON CONFERENCE
Role: Principal Investigator
R13GM052383
(CLAPHAM, DAVID E.)
Sep 1, 1995 - Aug 31, 1996
NIH/NIGMS
ORGANELLAR ION CHANNELS AND TRANSPORTERS
Role: Principal Investigator
R13ES007567
(CLAPHAM, DAVID E.)
Jun 15, 1995 - Dec 15, 1995
NIH/NIEHS
GORDON CONFERENCE ON CALCIUM SIGNALLING
Role: Principal Investigator
R01HL053483
(CLAPHAM, DAVID E.)
Dec 1, 1994 - Nov 30, 2004
NIH/NHLBI
G-PROTEIN GATING OF THE INWARD RECTIFIER K+ CHANNEL
Role: Principal Investigator
R01HL041303
(CLAPHAM, DAVID E.)
Jul 1, 1988 - Nov 30, 1998
NIH/NHLBI
INTRACELLULAR CALCIUM REGULATION IN XENOPUS OOCYTES
Role: Principal Investigator
R01HL034873
(CLAPHAM, DAVID E.)
Jan 1, 1985 - Jul 31, 1995
NIH/NHLBI
INTRACELLULAR REGULATION OF CARDIAC K+ CHANNELS
Role: Principal Investigator
T32HL007572
(PU, WILLIAM TSWENCHING)
Jan 1, 1983 - Jun 30, 2026
NIH
Research Methods in Pediatric Cardiovascular Disease
Role: Principal Investigator
Bibliographic
selected publications
Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can
login
to make corrections and additions.
Newest
|
Oldest
|
Most Cited
|
Most Discussed
|
Timeline
|
Field Summary
|
Plain Text
PMC Citations
indicate the number of times the publication was cited by articles in PubMed Central, and the
Altmetric
score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.)
Fields
are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication.
Translation
tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
Miller AN, Houlihan PR, Matamala E, Cabezas-Bratesco D, Lee GY, Cristofori-Armstrong B, Dilan TL, Sanchez-Martinez S, Matthies D, Yan R, Yu Z, Ren D, Brauchi SE,
Clapham DE
. The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins. bioRxiv. 2022 Sep 03.
PMID:
36263072
; PMCID:
PMC9580380
.
Citations:
Sheu SH,
Upadhyayula S
, Dupuy V, Pang S, Deng F, Wan J, Walpita D, Pasolli HA, Houser J, Sanchez-Martinez S, Brauchi SE, Banala S, Freeman M, Xu CS,
Kirchhausen T
, Hess HF, Lavis L, Li Y, Chaumont-Dubel S,
Clapham DE
. A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell. 2022 09 01; 185(18):3390-3407.e18.
PMID:
36055200
; PMCID:
PMC9789380
.
Citations:
4
Fields:
Cel
Cell Biology
Translation:
Cells
Bulumulla C, Krasley AT, Cristofori-Armstrong B, Valinsky WC, Walpita D, Ackerman D,
Clapham DE
, Beyene AG. Visualizing synaptic dopamine efflux with a 2D composite nanofilm. Elife. 2022 07 04; 11.
PMID:
35786443
; PMCID:
PMC9363124
.
Citations:
Fields:
Bio
Biology
Clapham DE
, Hulse RE. Sperm CatSper ion channel swims into sharper focus. Nature. 2021 Jul; 595(7869):654-655.
PMID:
34290412
.
Citations:
Fields:
Sci
Science
Bernal L, Sotelo-Hitschfeld P, König C, Sinica V, Wyatt A, Winter Z, Hein A, Touska F, Reinhardt S, Tragl A, Kusuda R, Wartenberg P, Sclaroff A, Pfeifer JD, Ectors F, Dahl A, Freichel M, Vlachova V, Brauchi S, Roza C, Boehm U,
Clapham DE
,
Lennerz JK
, Zimmermann K. Odontoblast TRPC5 channels signal cold pain in teeth. Sci Adv. 2021 03; 7(13).
PMID:
33771873
; PMCID:
PMC7997515
.
Citations:
8
Fields:
Sci
Science
Liu B, Mundt N, Miller M,
Clapham DE
, Kirichok Y, Lishko PV. Recording Electrical Currents across the Plasma Membrane of Mammalian Sperm Cells. J Vis Exp. 2021 02 14; (168).
PMID:
33645583
.
Citations:
1
Fields:
Bio
Biology
Med
Medicine (General)
Translation:
Humans
Animals
Cells
Gao S, Valinsky WC, On NC, Houlihan PR, Qu Q, Liu L, Pan X,
Clapham DE
, Yan N. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na+ channels in nanodisc. Proc Natl Acad Sci U S A. 2020 06 23; 117(25):14187-14193.
PMID:
32513729
.
Citations:
11
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Deo C, Sheu SH, Seo J,
Clapham DE
, Lavis LD. Isomeric Tuning Yields Bright and Targetable Red Ca2+ Indicators. J Am Chem Soc. 2019 09 04; 141(35):13734-13738.
PMID:
31430138
.
Citations:
15
Fields:
Che
Chemistry
Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J,
Clapham DE
, Zeng B, Li Z, Zhang J. Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function. Sci Adv. 2019 07; 5(7):eaaw7935.
PMID:
31355338
; PMCID:
PMC6656536
.
Citations:
34
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Duan J, Li Z, Li J, Hulse RE, Santa-Cruz A, Valinsky WC, Abiria SA, Krapivinsky G, Zhang J,
Clapham DE
. Structure of the mammalian TRPM7, a magnesium channel required during embryonic development. Proc Natl Acad Sci U S A. 2018 08 28; 115(35):E8201-E8210.
PMID:
30108148
; PMCID:
PMC6126765
.
Citations:
46
Fields:
Sci
Science
Translation:
Animals
Cells
Duan J, Li J, Zeng B, Chen GL, Peng X, Zhang Y, Wang J,
Clapham DE
, Li Z, Zhang J. Structure of the mouse TRPC4 ion channel. Nat Commun. 2018 08 06; 9(1):3102.
PMID:
30082700
.
Citations:
53
Fields:
Bio
Biology
Sci
Science
Translation:
Humans
Animals
Cells
Hulse RE, Li Z, Huang RK, Zhang J,
Clapham DE
. Cryo-EM structure of the polycystin 2-l1 ion channel. Elife. 2018 07 13; 7.
PMID:
30004384
.
Citations:
19
Fields:
Bio
Biology
Translation:
Humans
Cells
Clapham DE
. Influences: Short circuits. J Gen Physiol. 2018 04 02; 150(4):513-515.
PMID:
29559507
; PMCID:
PMC5881450
.
Citations:
1
Fields:
Phy
Physiology
Duan J, Li Z, Li J, Santa-Cruz A, Sanchez-Martinez S, Zhang J,
Clapham DE
. Structure of full-length human TRPM4. Proc Natl Acad Sci U S A. 2018 03 06; 115(10):2377-2382.
PMID:
29463718
; PMCID:
PMC5877947
.
Citations:
35
Fields:
Sci
Science
Translation:
Humans
Liu X, Vien T, Duan J, Sheu SH, DeCaen PG,
Clapham DE
. Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium. Elife. 2018 02 14; 7.
PMID:
29443690
.
Citations:
52
Fields:
Bio
Biology
Translation:
Humans
Animals
Cells
Krapivinsky G, Krapivinsky L,
Renthal NE
, Santa-Cruz A, Manasian Y,
Clapham DE
. Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression. Proc Natl Acad Sci U S A. 2017 08 22; 114(34):E7092-E7100.
PMID:
28784805
; PMCID:
PMC5576826
.
Citations:
13
Fields:
Sci
Science
Translation:
Humans
Cells
Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG,
Clapham DE
. TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles. Proc Natl Acad Sci U S A. 2017 07 25; 114(30):E6079-E6088.
PMID:
28696294
; PMCID:
PMC5544332
.
Citations:
41
Fields:
Sci
Science
Translation:
Humans
Cells
Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X,
Clapham DE
. CatSper? regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility. Elife. 2017 02 23; 6.
PMID:
28226241
.
Citations:
53
Fields:
Bio
Biology
Translation:
Animals
Cells
Platt CD
,
Chou J
, Houlihan P,
Badran YR
, Kumar L,
Bainter W
, Poliani PL, Perez CJ, Dent SYR,
Clapham DE
, Benavides F,
Geha RS
. Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function. J Allergy Clin Immunol. 2017 Dec; 140(6):1651-1659.e1.
PMID:
28192143
; PMCID:
PMC6170198
.
Citations:
18
Fields:
All
Allergy and Immunology
Translation:
Humans
Animals
Cells
Pablo JL, DeCaen PG,
Clapham DE
. Progress in ciliary ion channel physiology. J Gen Physiol. 2017 Jan; 149(1):37-47.
PMID:
27999145
; PMCID:
PMC5217089
.
Citations:
17
Fields:
Phy
Physiology
Translation:
Humans
Animals
Cells
Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D,
Clapham DE
, Cao E. The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs. Cell. 2016 Oct 20; 167(3):763-773.e11.
PMID:
27768895
.
Citations:
97
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
DeCaen PG, Liu X, Abiria S,
Clapham DE
. Atypical calcium regulation of the PKD2-L1 polycystin ion channel. Elife. 2016 06 27; 5.
PMID:
27348301
.
Citations:
24
Fields:
Bio
Biology
Translation:
Humans
Cells
Delling M,
Indzhykulian AA
, Liu X, Li Y, Xie T,
Corey DP
,
Clapham DE
. Primary cilia are not calcium-responsive mechanosensors. Nature. 2016 Mar 31; 531(7596):656-60.
PMID:
27007841
; PMCID:
PMC4851444
.
Citations:
147
Fields:
Sci
Science
Translation:
Animals
Cells
Chaudhuri D, Artiga DJ, Abiria SA,
Clapham DE
. Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition. Proc Natl Acad Sci U S A. 2016 Mar 29; 113(13):E1872-80.
PMID:
26976564
; PMCID:
PMC4822583
.
Citations:
47
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Naylor CE, Bagnéris C, DeCaen PG, Sula A, Scaglione A,
Clapham DE
, Wallace BA. Molecular basis of ion permeability in a voltage-gated sodium channel. EMBO J. 2016 Apr 15; 35(8):820-30.
PMID:
26873592
.
Citations:
45
Fields:
Bio
Biotechnology
Mol
Molecular Biology
Translation:
Humans
Cells
Blair NT, Philipson BI, Richards PM, Doerner JF, Segura A, Silver WL,
Clapham DE
. Naturally Produced Defensive Alkenal Compounds Activate TRPA1. Chem Senses. 2016 05; 41(4):281-92.
PMID:
26843529
; PMCID:
PMC5863776
.
Citations:
2
Fields:
Bio
Biochemistry
Translation:
Humans
Animals
Cells
Syeda SS, Carlson EJ, Miller MR, Francis R,
Clapham DE
, Lishko PV, Hawkinson JE, Hook D, Georg GI. The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex. ACS Chem Biol. 2016 Feb 19; 11(2):452-9.
PMID:
26674547
; PMCID:
PMC4761407
.
Citations:
2
Fields:
Bio
Biochemistry
Bio
Biology
Translation:
Humans
Animals
Cells
Doerner JF, Delling M,
Clapham DE
. Ion channels and calcium signaling in motile cilia. Elife. 2015 Dec 09; 4.
PMID:
26650848
.
Citations:
12
Fields:
Bio
Biology
Clapham DE
. Structural biology: Pain-sensing TRPA1 channel resolved. Nature. 2015 Apr 23; 520(7548):439-41.
PMID:
25855290
.
Citations:
3
Fields:
Sci
Science
Translation:
Humans
Cai X, Wang X, Patel S,
Clapham DE
. Insights into the early evolution of animal calcium signaling machinery: a unicellular point of view. Cell Calcium. 2015 Mar; 57(3):166-73.
PMID:
25498309
; PMCID:
PMC4355082
.
Citations:
18
Fields:
Cel
Cell Biology
Met
Metabolism
Translation:
Animals
Cells
DeCaen PG, Takahashi Y, Krulwich TA, Ito M,
Clapham DE
. Ionic selectivity and thermal adaptations within the voltage-gated sodium channel family of alkaliphilic Bacillus. Elife. 2014 Nov 11; 3.
PMID:
25385530
.
Citations:
16
Fields:
Bio
Biology
Translation:
Cells
Kahle KT
, Gao G, Zhang J, Latremoliere A, Andrews N, Shang Y, Alessi D,
Woolf C
,
Elledge S
,
Clapham D
. Ronald R. Tasker Young Investigator Award 165 Promoting Endogenous GABAergic Analgesia via Kinase Modulation of Neuronal Ion Plasticity. Neurosurgery. 2014 Aug; 61 Suppl 1:214.
PMID:
25032616
.
Citations:
Cai X, Wang X,
Clapham DE
. Early evolution of the eukaryotic Ca2+ signaling machinery: conservation of the CatSper channel complex. Mol Biol Evol. 2014 Oct; 31(10):2735-40.
PMID:
25063443
; PMCID:
PMC4169769
.
Citations:
18
Fields:
Mol
Molecular Biology
Translation:
Animals
Cells
Krapivinsky G, Krapivinsky L, Manasian Y,
Clapham DE
. The TRPM7 chanzyme is cleaved to release a chromatin-modifying kinase. Cell. 2014 May 22; 157(5):1061-72.
PMID:
24855944
; PMCID:
PMC4156102
.
Citations:
68
Fields:
Cel
Cell Biology
Translation:
Humans
Animals
Cells
Bagnéris C, DeCaen PG, Naylor CE, Pryde DC, Nobeli I,
Clapham DE
, Wallace BA. Prokaryotic NavMs channel as a structural and functional model for eukaryotic sodium channel antagonism. Proc Natl Acad Sci U S A. 2014 Jun 10; 111(23):8428-33.
PMID:
24850863
.
Citations:
63
Fields:
Sci
Science
Translation:
Humans
Cells
Chung JJ, Shim SH, Everley RA,
Gygi SP
, Zhuang X,
Clapham DE
. Structurally distinct Ca(2+) signaling domains of sperm flagella orchestrate tyrosine phosphorylation and motility. Cell. 2014 May 08; 157(4):808-22.
PMID:
24813608
; PMCID:
PMC4032590
.
Citations:
80
Fields:
Cel
Cell Biology
Translation:
Animals
Cells
Kahle KT
,
Khanna A
,
Clapham DE
,
Woolf CJ
. Therapeutic restoration of spinal inhibition via druggable enhancement of potassium-chloride cotransporter KCC2-mediated chloride extrusion in peripheral neuropathic pain. JAMA Neurol. 2014 May; 71(5):640-5.
PMID:
24615367
; PMCID:
PMC4465580
.
Citations:
20
Fields:
Neu
Neurology
Translation:
Humans
Animals
Cells
Chaudhuri D,
Clapham DE
. Outstanding questions regarding the permeation, selectivity, and regulation of the mitochondrial calcium uniporter. Biochem Biophys Res Commun. 2014 Jul 11; 449(4):367-9.
PMID:
24792175
.
Citations:
4
Fields:
Bio
Biochemistry
Bio
Biophysics
Translation:
Humans
Cells
Py BF, Jin M, Desai BN,
Penumaka A
, Zhu H, Kober M, Dietrich A, Lipinski MM, Henry T,
Clapham DE
, Yuan J. Caspase-11 controls interleukin-1ß release through degradation of TRPC1. Cell Rep. 2014 Mar 27; 6(6):1122-1128.
PMID:
24630989
.
Citations:
53
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Humans
Animals
Cells
Riccio A, Li Y, Tsvetkov E, Gapon S,
Yao GL
, Smith KS,
Engin E
, Rudolph U,
Bolshakov VY
,
Clapham DE
. Decreased anxiety-like behavior and Gaq/11-dependent responses in the amygdala of mice lacking TRPC4 channels. J Neurosci. 2014 Mar 05; 34(10):3653-67.
PMID:
24599464
.
Citations:
47
Fields:
Neu
Neurology
Translation:
Animals
Cells
Tsai MF, Jiang D, Zhao L,
Clapham D
, Miller C. Functional reconstitution of the mitochondrial Ca2+/H+ antiporter Letm1. J Gen Physiol. 2014 Jan; 143(1):67-73.
PMID:
24344246
.
Citations:
60
Fields:
Phy
Physiology
Translation:
Humans
DeCaen PG, Delling M, Vien TN,
Clapham DE
. Direct recording and molecular identification of the calcium channel of primary cilia. Nature. 2013 Dec 12; 504(7479):315-8.
PMID:
24336289
; PMCID:
PMC4073646
.
Citations:
150
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Delling M, DeCaen PG, Doerner JF, Febvay S,
Clapham DE
. Primary cilia are specialized calcium signalling organelles. Nature. 2013 Dec 12; 504(7479):311-4.
PMID:
24336288
; PMCID:
PMC4112737
.
Citations:
237
Fields:
Sci
Science
Translation:
Humans
Animals
Cells
Carvacho I, Lee HC, Fissore RA,
Clapham DE
. TRPV3 channels mediate strontium-induced mouse-egg activation. Cell Rep. 2013 Dec 12; 5(5):1375-86.
PMID:
24316078
; PMCID:
PMC3918412
.
Citations:
34
Fields:
Cel
Cell Biology
Mol
Molecular Biology
Translation:
Animals
Cells
Clapham DE
. The mother of all endocytosis. Elife. 2013 Nov 26; 2:e01738.
PMID:
24282238
.
Citations:
2
Fields:
Bio
Biology
Translation:
Animals
Cells
Sancak Y, Markhard AL, Kitami T, Kovács-Bogdán E, Kamer KJ, Udeshi ND, Carr SA, Chaudhuri D,
Clapham DE
, Li AA,
Calvo SE
, Goldberger O,
Mootha VK
. EMRE is an essential component of the mitochondrial calcium uniporter complex. Science. 2013 Dec 13; 342(6164):1379-82.
PMID:
24231807
.
Citations:
298
Fields:
Sci
Science
Translation:
Humans
Cells
Clapham DE
. Sperm BerserKers. Elife. 2013 Oct 08; 2:e01469.
PMID:
24137547
.
Citations:
6
Fields:
Bio
Biology
Translation:
Humans
Cells
Zeng XH, Navarro B, Xia XM,
Clapham DE
, Lingle CJ. Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa. J Gen Physiol. 2013 Sep; 142(3):305-13.
PMID:
23980198
.
Citations:
25
Fields:
Phy
Physiology
Translation:
Animals
Cells
Sah R, Mesirca P, Van den Boogert M, Rosen J, Mably J, Mangoni ME,
Clapham DE
. Ion channel-kinase TRPM7 is required for maintaining cardiac automaticity. Proc Natl Acad Sci U S A. 2013 Aug 06; 110(32):E3037-46.
PMID:
23878236
; PMCID:
PMC3740880
.
Citations:
50
Fields:
Sci
Science
Translation:
Animals
Cells
Mesirca P, Marger L, Toyoda F, Rizzetto R, Audoubert M, Dubel S, Torrente AG, Difrancesco ML, Muller JC, Leoni AL, Couette B, Nargeot J,
Clapham DE
, Wickman K, Mangoni ME. The G-protein-gated K+ channel, IKACh, is required for regulation of pacemaker activity and recovery of resting heart rate after sympathetic stimulation. J Gen Physiol. 2013 Aug; 142(2):113-26.
PMID:
23858001
.
Citations:
33
Fields:
Phy
Physiology
Translation:
Animals
Cells
Chaudhuri D, Sancak Y,
Mootha VK
,
Clapham DE
. MCU encodes the pore conducting mitochondrial calcium currents. Elife. 2013 Jun 04; 2:e00704.
PMID:
23755363
.
Citations:
93
Fields:
Bio
Biology
Translation:
Humans
Cells
Sah R, Mesirca P, Mason X, Gibson W, Bates-Withers C, Van den Boogert M, Chaudhuri D,
Pu WT
, Mangoni ME,
Clapham DE
. Timing of myocardial trpm7 deletion during cardiogenesis variably disrupts adult ventricular function, conduction, and repolarization. Circulation. 2013 Jul 09; 128(2):101-14.
PMID:
23734001
; PMCID: