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Kurt D Christensen, Ph.D.


A future where genomic information is readily available is rapidly approaching. Whether this information improves public health by improving patient care and empowering prevention, or whether it diminishes public health by motivating unnecessary follow-up testing and screening is unclear. I use my training in health economics, biochemistry, public health, and health behavior and health education to address these issues by focusing on three interrelated questions: 1) How do patients and physicians respond, behaviorally and psychologically, to information generated from emerging genomic technologies like whole genome sequencing? 2) What is the healthcare service and economic impact of integrating genomics into the everyday practice of medicine? 3) How can programs be improved to maximize the benefits and minimize the harms of genomic testing? The answers to these questions are essential as healthcare providers and policymakers make decisions about how to offer and support new genomic services.

The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. R01HL143295 (GREEN, ROBERT C.) Jul 1, 2019 - Jun 30, 2023
    Return of Genomic Results and Estimating Penetrance in Population-Based Cohorts
    Role Description: The overall goal of the proposed research is to develop and implement a genomic return of result process in the Framingham Heart Study and Jackson Heart Study cohorts and explore associated medical, behavioral and economic outcomes. We will also develop ways to automate and streamline genomic variant interpretation at scale, and develop analyses to aid assessment of penetrance.
    Role: Co-Investigator
  2. 20182750 (CHRISTENSEN, KURT DEREK) Feb 12, 2019 - Dec 31, 2022
    Sanford Health
    Medical/Economic ImpactT and Behavioral Responses to Integrating the Sanford ChipS (METRICS) Study
    Role Description: This goal of this research agreement is to summarize the impact of integrating pharmacogenetic and disease predisposition information into patient care within primary care settings, including the effect on clinician preparedness, provider and patient behaviors, medical and economic outcomes, and familial outcomes.
    Role: Principal Investigators
  3. R01HG009922 (GREEN, ROBERT C.) Sep 21, 2018 - Jun 30, 2021
    Experiences and Outcomes in Early Adopters of Predispositional Sequencing
    Role Description: The objective of this research is to aggregate data from, and assess the value of, personal predispositional genome sequencing among participants in present day projects focused on sequencing apparently healthy individuals.
    Role: Co-Investigator
  4. R01HD090019 (WU, ANN CHEN) Sep 11, 2017 - May 31, 2022
    Precision Medicine Policy and Treatment (PreEMPT) Model
    Role Description: This goal of this grant is to develop a detailed computer microsimulation model capable of simulating the clinical benefits, potential risks, and cost consequences associated with the integration of different genomic sequencing screening strategies into clinical care.
    Role: Co-Investigator
  5. FA8650-17-2-6704 (GREEN, ROBERT C.) Jan 1, 2017 - Dec 31, 2019
    MilSeq: Enabling Personalized Medicine through Exome Sequencing in the U.S. Air Force
    Role Description: The goal of this project is to test a pilot protocol for integrating genomic sequencing into the care of active duty airmen.
    Role: Co-Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Petry NJ, Baye JF, Frear S, Jacobsen K, Massmann A, Schultz A, Heukelom JV, Christensen K. Progression of precision statin prescribing for reduction of statin-associated muscle symptoms. Pharmacogenomics. 2022 07; 23(10):585-596. PMID: 35775396.
    Citations:    Fields:    
  2. Zeng C, Bastarache LA, Tao R, Venner E, Hebbring S, Andujar JD, Bland ST, Crosslin DR, Pratap S, Cooley A, Pacheco JA, Christensen KD, Perez E, Zawatsky CLB, Witkowski L, Zouk H, Weng C, Leppig KA, Sleiman PMA, Hakonarson H, Williams MS, Luo Y, Jarvik GP, Green RC, Chung WK, Gharavi AG, Lennon NJ, Rehm HL, Gibbs RA, Peterson JF, Roden DM, Wiesner GL, Denny JC. Association of Pathogenic Variants in Hereditary Cancer Genes With Multiple Diseases. JAMA Oncol. 2022 06 01; 8(6):835-844. PMID: 35446370; PMCID: PMC9026237.
    Citations:    Fields:    Translation:Humans
  3. Kunst N, Stout NK, O'Brien G, Christensen KD, McMahon PM, Wu AC, Diller LR, Yeh JM. Population-Based Newborn Screening for Germline TP53 Variants: Clinical Benefits, Cost-Effectiveness, and Value of Further Research. J Natl Cancer Inst. 2022 05 09; 114(5):722-731. PMID: 35043946; PMCID: PMC9086756.
    Citations:    Fields:    Translation:HumansCellsPHPublic Health
  4. Armstrong B, Christensen KD, Genetti CA, Parad RB, Robinson JO, Blout Zawatsky CL, Zettler B, Beggs AH, Holm IA, Green RC, McGuire AL, Smith HS, Pereira S. Parental Attitudes Toward Standard Newborn Screening and Newborn Genomic Sequencing: Findings From the BabySeq Study. Front Genet. 2022; 13:867371. PMID: 35571041; PMCID: PMC9091188.
  5. Leppig KA, Kulchak Rahm A, Appelbaum P, Aufox S, Bland ST, Buchanan A, Christensen KD, Chung WK, Clayton EW, Crosslin D, Denny J, DeVange S, Gordon A, Green RC, Hakonarson H, Harr MH, Henrikson N, Hoell C, Holm IA, Kullo IJ, Jarvik GP, Lammers PE, Larson EB, Lindor NM, Marasa M, Myers MF, Perez E, Peterson JF, Pratap S, Prows CA, Ralston JD, Rasouly HM, Roden DM, Sharp RR, Singh R, Shaibi G, Smith ME, Sturm A, Thiese HA, Van Driest SL, Williams J, Williams MS, Wynn J, Blout Zawatsky CL, Wiesner GL. The reckoning: The return of genomic results to 1444 participants across the eMERGE3 Network. Genet Med. 2022 05; 24(5):1130-1138. PMID: 35216901.
    Citations: 1     Fields:    Translation:Humans
  6. Hajek C, Hutchinson AM, Galbraith LN, Green RC, Murray MF, Petry N, Preys CL, Zawatsky CLB, Zoltick ES, Christensen KD. Improved provider preparedness through an 8-part genetics and genomic education program. Genet Med. 2022 01; 24(1):214-224. PMID: 34906462; PMCID: PMC9121992.
    Citations:    Fields:    Translation:Humans
  7. Blout Zawatsky CL, Shah N, Machini K, Perez E, Christensen KD, Zouk H, Steeves M, Koch C, Uveges M, Shea J, Gold N, Krier J, Boutin N, Mahanta L, Rehm HL, Weiss ST, Karlson EW, Smoller JW, Lebo MS, Green RC. Returning actionable genomic results in a research biobank: Analytic validity, clinical implementation, and resource utilization. Am J Hum Genet. 2021 12 02; 108(12):2224-2237. PMID: 34752750; PMCID: PMC8715145.
    Citations: 1     Fields:    Translation:Humans
  8. Pereira S, Smith HS, Frankel LA, Christensen KD, Islam R, Robinson JO, Genetti CA, Blout Zawatsky CL, Zettler B, Parad RB, Waisbren SE, Beggs AH, Green RC, Holm IA, McGuire AL. Psychosocial Effect of Newborn Genomic Sequencing on Families in the BabySeq Project: A Randomized Clinical Trial. JAMA Pediatr. 2021 11 01; 175(11):1132-1141. PMID: 34424265; PMCID: PMC8383160.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  9. Brunette CA, Dong OM, Vassy JL, Danowski ME, Alexander N, Antwi AA, Christensen KD. A Cost-Consequence Analysis of Preemptive SLCO1B1 Testing for Statin Myopathy Risk Compared to Usual Care. J Pers Med. 2021 Oct 31; 11(11). PMID: 34834475; PMCID: PMC8624003.
  10. Wynn J, Milo Rasouly H, Vasquez-Loarte T, Saami AM, Weiss R, Ziniel SI, Appelbaum PS, Wright Clayton E, Christensen KD, Fasel D, Green RC, Hain HS, Harr M, Hoell C, Kullo IJ, Leppig KA, Myers MF, Pacyna JE, Perez EF, Prows CA, Kulchak Rahm A, Campbell-Salome G, Sharp RR, Smith ME, Wiesner GL, Williams JL, Blout Zawatsky CL, Gharavi AG, Chung WK, Holm IA. Do research participants share genomic screening results with family members? J Genet Couns. 2022 04; 31(2):447-458. PMID: 34665896; PMCID: PMC8983417.
    Citations: 1     Fields:    Translation:Humans
  11. O'Brien G, Christensen KD, Sullivan HK, Stout NK, Diller L, Yeh JM, Wu AC. Estimated Cost-effectiveness of Genetic Testing in Siblings of Newborns With Cancer Susceptibility Gene Variants. JAMA Netw Open. 2021 10 01; 4(10):e2129742. PMID: 34661666; PMCID: PMC8524309.
    Citations: 2     Fields:    Translation:Humans
  12. Christensen KD, Schonman EF, Robinson JO, Roberts JS, Diamond PM, Lee KB, Green RC, McGuire AL. Behavioral and psychological impact of genome sequencing: a pilot randomized trial of primary care and cardiology patients. NPJ Genom Med. 2021 Aug 24; 6(1):72. PMID: 34429410.
  13. Schwartz TS, Christensen KD, Uveges MK, Waisbren SE, McGuire AL, Pereira S, Robinson JO, Beggs AH, Green RC, Bachmann GA, Rabson AB, Holm IA. Effects of participation in a U.S. trial of newborn genomic sequencing on parents at risk for depression. J Genet Couns. 2022 02; 31(1):218-229. PMID: 34309124; PMCID: PMC8789951.
    Citations:    Fields:    Translation:Humans
  14. Galbraith LN, Preys CL, Rehm HL, Scheuner MT, Hajek C, Green RC, Christensen KD. Primary care providers' responses to unsolicited Lynch syndrome secondary findings of varying clinical significance. Genet Med. 2021 10; 23(10):1977-1983. PMID: 34113000; PMCID: PMC8487923.
    Citations: 1     Fields:    Translation:Humans
  15. Yeh JM, Stout NK, Chaudhry A, Christensen KD, Gooch M, McMahon PM, O'Brien G, Rehman N, Blout Zawatsky CL, Green RC, Lu CY, Rehm HL, Williams MS, Diller L, Wu AC. Universal newborn genetic screening for pediatric cancer predisposition syndromes: model-based insights. Genet Med. 2021 07; 23(7):1366-1371. PMID: 33767345; PMCID: PMC8263476.
    Citations: 5     Fields:    Translation:HumansPHPublic Health
  16. Christensen KD, Bell M, Zawatsky CLB, Galbraith LN, Green RC, Hutchinson AM, Jamal L, LeBlanc JL, Leonhard JR, Moore M, Mullineaux L, Petry N, Platt DM, Shaaban S, Schultz A, Tucker BD, Van Heukelom J, Wheeler E, Zoltick ES, Hajek C. Precision Population Medicine in Primary Care: The Sanford Chip Experience. Front Genet. 2021; 12:626845. PMID: 33777099.
    Citations: 9     
  17. Pereira S, Hsu RL, Islam R, Robinson JO, Ramapriyan R, Sirotich E, Maxwell MD, Majumder M, Blout CL, Christensen KD, Mehlman M, Parasidis E, Gardner CL, Killian JM, De Castro M, Green RC, McGuire AL. Airmen and health-care providers' attitudes toward the use of genomic sequencing in the US Air Force: findings from the MilSeq Project. Genet Med. 2020 12; 22(12):2003-2010. PMID: 32807975; PMCID: PMC7710566.
    Citations: 1     Fields:    Translation:Humans
  18. Wiesner GL, Kulchak Rahm A, Appelbaum P, Aufox S, Bland ST, Blout CL, Christensen KD, Chung WK, Clayton EW, Green RC, Harr MH, Henrikson N, Hoell C, Holm IA, Jarvik GP, Kullo IJ, Lammers PE, Larson EB, Lindor NM, Marasa M, F Myers M, Peterson JF, Prows CA, Ralston JD, Milo Rasouly H, Sharp RR, Smith ME, Van Driest SL, Williams JL, Williams MS, Wynn J, Leppig KA. Returning Results in the Genomic Era: Initial Experiences of the eMERGE Network. J Pers Med. 2020 Apr 27; 10(2). PMID: 32349224.
    Citations: 13     
  19. Christensen KD, Karlawish J, Roberts JS, Uhlmann WR, Harkins K, Wood EM, Obisesan TO, Le LQ, Cupples LA, Zoltick ES, Johnson MS, Bradbury MK, Waterston LB, Chen CA, Feldman S, Perry DL, Green RC. Disclosing genetic risk for Alzheimer's dementia to individuals with mild cognitive impairment. Alzheimers Dement (N Y). 2020; 6(1):e12002. PMID: 32211507; PMCID: PMC7087414.
    Citations: 9     
  20. Mackay ZP, Dukhovny D, Phillips KA, Beggs AH, Green RC, Parad RB, Christensen KD. Quantifying Downstream Healthcare Utilization in Studies of Genomic Testing. Value Health. 2020 05; 23(5):559-565. PMID: 32389220.
    Citations: 3     Fields:    Translation:Humans
  21. Robinson JO, Wynn J, Biesecker B, Biesecker LG, Bernhardt B, Brothers KB, Chung WK, Christensen KD, Green RC, McGuire AL, Hart MR, Griesemer I, Patrick DL, Rini C, Veenstra D, Cronin AM, Gray SW. Psychological outcomes related to exome and genome sequencing result disclosure: a meta-analysis of seven Clinical Sequencing Exploratory Research (CSER) Consortium studies. Genet Med. 2019 12; 21(12):2781-2790. PMID: 31189963; PMCID: PMC7260995.
    Citations: 23     Fields:    Translation:Humans
  22. Hart MR, Biesecker BB, Blout CL, Christensen KD, Amendola LM, Bergstrom KL, Biswas S, Bowling KM, Brothers KB, Conlin LK, Cooper GM, Dulik MC, East KM, Everett JN, Finnila CR, Ghazani AA, Gilmore MJ, Goddard KAB, Jarvik GP, Johnston JJ, Kauffman TL, Kelley WV, Krier JB, Lewis KL, McGuire AL, McMullen C, Ou J, Plon SE, Rehm HL, Richards CS, Romasko EJ, Sagardia AM, Spinner NB, Thompson ML, Turbitt E, Vassy JL, Wilfond BS, Veenstra DL, Berg JS, Green RC, Biesecker LG, Hindorff LA. Correction: Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study. Genet Med. 2019 May; 21(5):1261-1262. PMID: 30670880.
    Citations: 1     Fields:    
  23. Hylind RJ, Chandler SF, Beausejour Ladouceur V, Roberts AE, Bezzerides V, Christensen KD, Coggins M, Lakdawala NK, MacRae CA, Abrams DJ. Phenotypic Characterization of Individuals With Variants in Cardiovascular Genes in the Absence of a Primary Cardiovascular Indication for Testing. Circ Genom Precis Med. 2019 03; 12(3):e002463. PMID: 30919684.
    Citations:    Fields:    Translation:Humans
  24. Hart MR, Biesecker BB, Blout CL, Christensen KD, Amendola LM, Bergstrom KL, Biswas S, Bowling KM, Brothers KB, Conlin LK, Cooper GM, Dulik MC, East KM, Everett JN, Finnila CR, Ghazani AA, Gilmore MJ, Goddard KAB, Jarvik GP, Johnston JJ, Kauffman TL, Kelley WV, Krier JB, Lewis KL, McGuire AL, McMullen C, Ou J, Plon SE, Rehm HL, Richards CS, Romasko EJ, Miren Sagardia A, Spinner NB, Thompson ML, Turbitt E, Vassy JL, Wilfond BS, Veenstra DL, Berg JS, Green RC, Biesecker LG, Hindorff LA. Secondary findings from clinical genomic sequencing: prevalence, patient perspectives, family history assessment, and health-care costs from a multisite study. Genet Med. 2019 05; 21(5):1100-1110. PMID: 30287922; PMCID: PMC6450774.
    Citations: 44     Fields:    Translation:Humans
  25. Christensen KD, Phillips KA, Green RC, Dukhovny D. Cost Analyses of Genomic Sequencing: Lessons Learned from the MedSeq Project. Value Health. 2018 09; 21(9):1054-1061. PMID: 30224109; PMCID: PMC6444358.
    Citations: 4     Fields:    Translation:Humans
  26. Phillips KA, Deverka PA, Marshall DA, Wordsworth S, Regier DA, Christensen KD, Buchanan J. Methodological Issues in Assessing the Economic Value of Next-Generation Sequencing Tests: Many Challenges and Not Enough Solutions. Value Health. 2018 09; 21(9):1033-1042. PMID: 30224106.
    Citations: 14     Fields:    Translation:Humans
  27. Holm IA, Agrawal PB, Ceyhan-Birsoy O, Christensen KD, Fayer S, Frankel LA, Genetti CA, Krier JB, LaMay RC, Levy HL, McGuire AL, Parad RB, Park PJ, Pereira S, Rehm HL, Schwartz TS, Waisbren SE, Yu TW, Green RC, Beggs AH. The BabySeq project: implementing genomic sequencing in newborns. BMC Pediatr. 2018 07 09; 18(1):225. PMID: 29986673.
    Citations: 37     Fields:    Translation:HumansPHPublic Health
  28. Christensen KD, Vassy JL, Phillips KA, Blout CL, Azzariti DR, Lu CY, Robinson JO, Lee K, Douglas MP, Yeh JM, Machini K, Stout NK, Rehm HL, McGuire AL, Green RC, Dukhovny D. Short-term costs of integrating whole-genome sequencing into primary care and cardiology settings: a pilot randomized trial. Genet Med. 2018 12; 20(12):1544-1553. PMID: 29565423; PMCID: PMC6151171.
    Citations: 11     Fields:    Translation:Humans
  29. Mitchell PB, Ziniel SI, Savage SK, Christensen KD, Weitzman ER, Green RC, Huntington NL, Mathews DJ, Holm IA. Enhancing Autonomy in Biobank Decisions: Too Much of a Good Thing? J Empir Res Hum Res Ethics. 2018 04; 13(2):125-138. PMID: 29471711; PMCID: PMC8793343.
    Citations: 3     Fields:    Translation:Humans
  30. Christensen KD, Bernhardt BA, Jarvik GP, Hindorff LA, Ou J, Biswas S, Powell BC, Grundmeier RW, Machini K, Karavite DJ, Pennington JW, Krantz ID, Berg JS, Goddard KAB. Anticipated responses of early adopter genetic specialists and nongenetic specialists to unsolicited genomic secondary findings. Genet Med. 2018 10; 20(10):1186-1195. PMID: 29388940; PMCID: PMC6103906.
    Citations: 6     Fields:    Translation:Humans
  31. Roberts JS, Robinson JO, Diamond PM, Bharadwaj A, Christensen KD, Lee KB, Green RC, McGuire AL. Patient understanding of, satisfaction with, and perceived utility of whole-genome sequencing: findings from the MedSeq Project. Genet Med. 2018 09; 20(9):1069-1076. PMID: 29300387; PMCID: PMC6034997.
    Citations: 21     Fields:    Translation:Humans
  32. Guan Y, Roter DL, Erby LH, Wolff JL, Gitlin LN, Roberts JS, Green RC, Christensen KD. Communication Predictors of Patient and Companion Satisfaction with Alzheimer's Genetic Risk Disclosure. J Health Commun. 2018; 23(8):807-814. PMID: 30325721; PMCID: PMC6452435.
    Citations: 2     Fields:    Translation:Humans
  33. Guan Y, Roter DL, Wolff JL, Gitlin LN, Christensen KD, Roberts JS, Green RC, Erby LH. The impact of genetic counselors' use of facilitative strategies on cognitive and emotional processing of genetic risk disclosure for Alzheimer's disease. Patient Educ Couns. 2018 05; 101(5):817-823. PMID: 29203084; PMCID: PMC5911203.
    Citations: 2     Fields:    Translation:Humans
  34. Christensen KD, Uhlmann WR, Roberts JS, Linnenbringer E, Whitehouse PJ, Royal CDM, Obisesan TO, Cupples LA, Butson MB, Fasaye GA, Hiraki S, Chen CA, Siebert U, Cook-Deegan R, Green RC. A randomized controlled trial of disclosing genetic risk information for Alzheimer disease via telephone. Genet Med. 2018 01; 20(1):132-141. PMID: 28726810; PMCID: PMC5897910.
    Citations: 21     Fields:    Translation:Humans
  35. Vassy JL, Christensen KD, Schonman EF, Blout CL, Robinson JO, Krier JB, Diamond PM, Lebo M, Machini K, Azzariti DR, Dukhovny D, Bates DW, MacRae CA, Murray MF, Rehm HL, McGuire AL, Green RC. The Impact of Whole-Genome Sequencing on the Primary Care and Outcomes of Healthy Adult Patients: A Pilot Randomized Trial. Ann Intern Med. 2017 08 01; 167(3):159-169. PMID: 28654958; PMCID: PMC5856654.
    Citations: 66     Fields:    Translation:Humans
  36. Christensen KD, Savage SK, Huntington NL, Weitzman ER, Ziniel SI, Bacon PL, Cacioppo CN, Green RC, Holm IA. Preferences for the Return of Individual Results From Research on Pediatric Biobank Samples. J Empir Res Hum Res Ethics. 2017 04; 12(2):97-106. PMID: 28421887; PMCID: PMC5407299.
    Citations: 9     Fields:    Translation:Humans
  37. Jamal L, Robinson JO, Christensen KD, Blumenthal-Barby J, Slashinski MJ, Perry DL, Vassy JL, Wycliff J, Green RC, McGuire AL. When bins blur: Patient perspectives on categories of results from clinical whole genome sequencing. AJOB Empir Bioeth. 2017 Apr-Jun; 8(2):82-88. PMID: 28949844; PMCID: PMC6647021.
    Citations: 17     Fields:    Translation:Humans
  38. Jamal L Robinson JO Christensen KD Blumenthal-Barby J Slashinski MJ Perry DL Vassy JL Wycliff J Green RC McGuire AL. When bins blur together: patient perspectives on categories of returnable results from clinical whole genome sequencing. AJOB Empir Bioeth. 2017. View Publication.
  39. Guan Y, Roter DL, Erby LH, Wolff JL, Gitlin LN, Roberts JS, Green RC, Christensen KD. Disclosing genetic risk of Alzheimer's disease to cognitively impaired patients and visit companions: Findings from the REVEAL Study. Patient Educ Couns. 2017 05; 100(5):927-935. PMID: 28012682; PMCID: PMC5400683.
    Citations: 10     Fields:    Translation:Humans
  40. Conway-Pearson LS, Christensen KD, Savage SK, Huntington NL, Weitzman ER, Ziniel SI, Bacon P, Cacioppo CN, Green RC, Holm IA. Family health history reporting is sensitive to small changes in wording. Genet Med. 2016 12; 18(12):1308-1311. PMID: 27148937; PMCID: PMC5097687.
    Citations: 1     Fields:    Translation:Humans
  41. Robinson JO, Carroll TM, Feuerman LZ, Perry DL, Hoffman-Andrews L, Walsh RC, Christensen KD, Green RC, McGuire AL. Participants and Study Decliners' Perspectives About the Risks of Participating in a Clinical Trial of Whole Genome Sequencing. J Empir Res Hum Res Ethics. 2016 02; 11(1):21-30. PMID: 26928896; PMCID: PMC4842131.
    Citations: 23     Fields:    Translation:Humans
  42. Baptista NM, Christensen KD, Carere DA, Broadley SA, Roberts JS, Green RC. Adopting genetics: motivations and outcomes of personal genomic testing in adult adoptees. Genet Med. 2016 09; 18(9):924-32. PMID: 26820063; PMCID: PMC4965328.
    Citations: 12     Fields:    Translation:Humans
  43. Christensen KD, Roberts JS, Whitehouse PJ, Royal CD, Obisesan TO, Cupples LA, Vernarelli JA, Bhatt DL, Linnenbringer E, Butson MB, Fasaye GA, Uhlmann WR, Hiraki S, Wang N, Cook-Deegan R, Green RC. Disclosing Pleiotropic Effects During Genetic Risk Assessment for Alzheimer Disease: A Randomized Trial. Ann Intern Med. 2016 Feb 02; 164(3):155-63. PMID: 26810768; PMCID: PMC4979546.
    Citations: 21     Fields:    Translation:Humans
  44. Lupo PJ, Robinson JO, Diamond PM, Jamal L, Danysh HE, Blumenthal-Barby J, Lehmann LS, Vassy JL, Christensen KD, Green RC, McGuire AL. Patients' perceived utility of whole-genome sequencing for their healthcare: findings from the MedSeq project. Per Med. 2016 Jan 01; 13(1):13-20. PMID: 27019659.
    Citations: 18     Fields:    
  45. Christensen KD, Dukhovny D, Siebert U, Green RC. Assessing the Costs and Cost-Effectiveness of Genomic Sequencing. J Pers Med. 2015 Dec 10; 5(4):470-86. PMID: 26690481; PMCID: PMC4695866.
    Citations: 43     
  46. Holm IA, Iles BR, Ziniel SI, Bacon PL, Savage SK, Christensen KD, Weitzman ER, Green RC, Huntington NL. Participant Satisfaction With a Preference-Setting Tool for the Return of Individual Research Results in Pediatric Genomic Research. J Empir Res Hum Res Ethics. 2015 Oct; 10(4):414-26. PMID: 26376753; PMCID: PMC6686662.
    Citations: 14     Fields:    Translation:Humans
  47. Christensen KD, Vassy JL, Jamal L, Lehmann LS, Slashinski MJ, Perry DL, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Murray MF, Green RC, McGuire AL. Are physicians prepared for whole genome sequencing? a qualitative analysis. Clin Genet. 2016 Feb; 89(2):228-34. PMID: 26080898; PMCID: PMC4683111.
    Citations: 61     Fields:    Translation:Humans
  48. Robinson CL, Jouni H, Kruisselbrink TM, Austin EE, Christensen KD, Green RC, Kullo IJ. Disclosing genetic risk for coronary heart disease: effects on perceived personal control and genetic counseling satisfaction. Clin Genet. 2016 Feb; 89(2):251-7. PMID: 25708169; PMCID: PMC6685535.
    Citations: 10     Fields:    Translation:Humans
  49. Christensen KD, Roberts JS, Zikmund-Fisher BJ, Kardia SL, McBride CM, Linnenbringer E, Green RC. Associations between self-referral and health behavior responses to genetic risk information. Genome Med. 2015; 7(1):10. PMID: 25642295.
    Citations: 13     Fields:    
  50. Besser AG, Sanderson SC, Roberts JS, Chen CA, Christensen KD, Lautenbach DM, Cupples LA, Green RC. Factors affecting recall of different types of personal genetic information about Alzheimer's disease risk: the REVEAL study. Public Health Genomics. 2015; 18(2):78-86. PMID: 25634646; PMCID: PMC4470386.
    Citations: 4     Fields:    Translation:Humans
  51. Vassy JL, Christensen KD, Slashinski MJ, Lautenbach DM, Raghavan S, Robinson JO, Blumenthal-Barby J, Feuerman LZ, Lehmann LS, Murray MF, Green RC, McGuire AL. 'Someday it will be the norm': physician perspectives on the utility of genome sequencing for patient care in the MedSeq Project. Per Med. 2015; 12(1):23-32. PMID: 25642274.
    Citations: 17     Fields:    
  52. McLaughlin HM, Ceyhan-Birsoy O, Christensen KD, Kohane IS, Krier J, Lane WJ, Lautenbach D, Lebo MS, Machini K, MacRae CA, Azzariti DR, Murray MF, Seidman CE, Vassy JL, Green RC, Rehm HL. A systematic approach to the reporting of medically relevant findings from whole genome sequencing. BMC Med Genet. 2014 Dec 14; 15:134. PMID: 25714468; PMCID: PMC4342199.
    Citations: 47     Fields:    Translation:Humans
  53. Khan CM, Rini C, Bernhardt BA, Roberts JS, Christensen KD, Evans JP, Brothers KB, Roche MI, Berg JS, Henderson GE. How can psychological science inform research about genetic counseling for clinical genomic sequencing? J Genet Couns. 2015 Apr; 24(2):193-204. PMID: 25488723; PMCID: PMC4777349.
    Citations: 8     Fields:    Translation:Humans
  54. Green RC, Christensen KD, Cupples LA, Relkin NR, Whitehouse PJ, Royal CD, Obisesan TO, Cook-Deegan R, Linnenbringer E, Butson MB, Fasaye GA, Levinson E, Roberts JS. A randomized noninferiority trial of condensed protocols for genetic risk disclosure of Alzheimer's disease. Alzheimers Dement. 2015 Oct; 11(10):1222-30. PMID: 25499536; PMCID: PMC4461546.
    Citations: 20     Fields:    Translation:Humans
  55. Christensen KD, Kalia SS, Green RC. UpToDate, Raby BA (Ed). Incidental findings from genetic testing. 2014. View Publication.
  56. Vassy JL, Lautenbach DM, McLaughlin HM, Kong SW, Christensen KD, Krier J, Kohane IS, Feuerman LZ, Blumenthal-Barby J, Roberts JS, Lehmann LS, Ho CY, Ubel PA, MacRae CA, Seidman CE, Murray MF, McGuire AL, Rehm HL, Green RC. The MedSeq Project: a randomized trial of integrating whole genome sequencing into clinical medicine. Trials. 2014 Mar 20; 15:85. PMID: 24645908.
    Citations: 78     Fields:    Translation:Humans
  57. Gray SW, Martins Y, Feuerman LZ, Bernhardt BA, Biesecker BB, Christensen KD, Joffe S, Rini C, Veenstra D, McGuire AL. Social and behavioral research in genomic sequencing: approaches from the Clinical Sequencing Exploratory Research Consortium Outcomes and Measures Working Group. Genet Med. 2014 Oct; 16(10):727-35. PMID: 24625446; PMCID: PMC4163120.
    Citations: 31     Fields:    Translation:Humans
  58. Christensen KD, Green RC. How could disclosing incidental information from whole-genome sequencing affect patient behavior? Per Med. 2013 Jun; 10(4). PMID: 24319470.
    Citations: 10     Fields:    
  59. Lautenbach DM, Christensen KD, Sparks JA, Green RC. Communicating genetic risk information for common disorders in the era of genomic medicine. Annu Rev Genomics Hum Genet. 2013; 14:491-513. PMID: 24003856.
    Citations: 69     Fields:    Translation:Humans
  60. Terry SF, Christensen KD, Metosky S, Rudofsky G, Deignan KP, Martinez H, Johnson-Moore P, Citrin T. Community engagement about genetic variation research. Popul Health Manag. 2012 Apr; 15(2):78-89. PMID: 21815821.
    Citations: 4     Fields:    Translation:Humans
  61. Roberts JS, Christensen KD, Green RC. Using Alzheimer's disease as a model for genetic risk disclosure: implications for personal genomics. Clin Genet. 2011 Nov; 80(5):407-14. PMID: 21696382.
    Citations: 40     Fields:    Translation:Humans
  62. Christensen KD, Roberts JS, Uhlmann WR, Green RC. Changes to perceptions of the pros and cons of genetic susceptibility testing after APOE genotyping for Alzheimer disease risk. Genet Med. 2011 May; 13(5):409-14. PMID: 21270636; PMCID: PMC3170997.
    Citations: 18     Fields:    Translation:Humans
  63. Hock KT, Christensen KD, Yashar BM, Roberts JS, Gollust SE, Uhlmann WR. Direct-to-consumer genetic testing: an assessment of genetic counselors' knowledge and beliefs. Genet Med. 2011 Apr; 13(4):325-32. PMID: 21233722; PMCID: PMC3804135.
    Citations: 29     Fields:    Translation:Humans
  64. Christensen KD, Roberts JS, Shalowitz DI, Everett JN, Kim SY, Raskin L, Gruber SB. Disclosing individual CDKN2A research results to melanoma survivors: interest, impact, and demands on researchers. Cancer Epidemiol Biomarkers Prev. 2011 Mar; 20(3):522-9. PMID: 21307304.
    Citations: 29     Fields:    Translation:Humans
  65. Roberts JS, Shalowitz DI, Christensen KD, Everett JN, Kim SY, Raskin L, Gruber SB. Returning individual research results: development of a cancer genetics education and risk communication protocol. J Empir Res Hum Res Ethics. 2010 Sep; 5(3):17-30. PMID: 20831418; PMCID: PMC3159194.
    Citations: 17     Fields:    Translation:Humans
  66. Christensen KD, Jayaratne TE, Roberts JS, Kardia SL, Petty EM. Understandings of basic genetics in the United States: results from a national survey of black and white men and women. Public Health Genomics. 2010; 13(7-8):467-76. PMID: 20203477; PMCID: PMC3025896.
    Citations: 33     Fields:    Translation:Humans
  67. Christensen KD, Roberts JS, Royal CD, Fasaye GA, Obisesan T, Cupples LA, Whitehouse PJ, Butson MB, Linnenbringer E, Relkin NR, Farrer L, Cook-Deegan R, Green RC. Incorporating ethnicity into genetic risk assessment for Alzheimer disease: the REVEAL study experience. Genet Med. 2008 Mar; 10(3):207-14. PMID: 18344711; PMCID: PMC2483343.
    Citations: 26     Fields:    Translation:Humans
  68. Harvey EK, Fogel CE, Peyrot M, Christensen KD, Terry SF, McInerney JD. Providers' knowledge of genetics: A survey of 5915 individuals and families with genetic conditions. Genet Med. 2007 May; 9(5):259-67. PMID: 17505202.
    Citations: 29     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.