Harvard Catalyst Profiles

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Jarrod Daniel Predina, M.D.


The research activities and funding listed below are automatically derived from NIH ExPORTER and other sources, which might result in incorrect or missing items. Faculty can login to make corrections and additions.
  1. F32CA210409 (PREDINA, JARROD D) Jul 6, 2016 - Jul 5, 2018
    Optimizing Immunotherapy Strategies to Eliminate Recurrences after Cancer Surgery
    Role: Principal Investigator

Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
  1. Onwugbufor MT, Predina JD, Osho AA, Schumacher LY. 10 Commandments of Robotic Lobectomy. Innovations (Phila). 2021 Mar-Apr; 16(2):123-126. PMID: 33829927.
    Citations:    Fields:    Translation:Humans
  2. Gangadharan S, Sarkaria IN, Rice D, Murthy S, Braun J, Kucharczuk J, Predina J, Singhal S. Multiinstitutional Phase 2 Clinical Trial of Intraoperative Molecular Imaging of Lung Cancer. Ann Thorac Surg. 2021 10; 112(4):1150-1159. PMID: 33221195.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  3. Predina JD, Haas AR, Martinez M, O'Brien S, Moon EK, Woodruff P, Stadanlick J, Corbett C, Frenzel-Sulyok L, Bryski MG, Eruslanov E, Deshpande C, Langer C, Aguilar LK, Guzik BW, Manzanera AG, Aguilar-Cordova E, Singhal S, Albelda SM. Neoadjuvant Gene-Mediated Cytotoxic Immunotherapy for Non-Small-Cell Lung Cancer: Safety and Immunologic Activity. Mol Ther. 2021 02 03; 29(2):658-670. PMID: 33160076.
    Citations: 3     Fields:    Translation:HumansCells
  4. Newton AD, Predina JD, Frenzel-Sulyok LG, Low PS, Singhal S, Roses RE. Intraoperative Molecular Imaging Utilizing a Folate Receptor-Targeted Near-Infrared Probe Can Identify Macroscopic Gastric Adenocarcinomas. Mol Imaging Biol. 2021 02; 23(1):11-17. PMID: 33033941.
    Citations: 2     Fields:    Translation:HumansCTClinical Trials
  5. Newton A, Predina J, Mison M, Runge J, Bradley C, Stefanovski D, Singhal S, Holt D. Intraoperative near-infrared imaging can identify canine mammary tumors, a spontaneously occurring, large animal model of human breast cancer. PLoS One. 2020; 15(6):e0234791. PMID: 32555698.
    Citations: 2     Fields:    Translation:HumansAnimals
  6. Corbett CJ, Frenzel Sulyok LG, Predina JD, Newton AD, Bryski MG, Xia L, Stadanlick J, Shin MH, Mahalingam SM, Low PS, Singhal S. Comparison of a Short Versus Long Stokes Shift Near-Infrared Dye During Intraoperative Molecular Imaging. Mol Imaging Biol. 2020 02; 22(1):144-155. PMID: 31820349.
    Citations: 1     Fields:    Translation:HumansAnimalsCells
  7. Newton AD, Predina JD, Shin MH, Frenzel-Sulyok LG, Vollmer CM, Drebin JA, Singhal S, Lee MK. Intraoperative Near-infrared Imaging Can Identify Neoplasms and Aid in Real-time Margin Assessment During Pancreatic Resection. Ann Surg. 2019 07; 270(1):12-20. PMID: 31188797.
    Citations: 16     Fields:    Translation:HumansCTClinical Trials
  8. Predina JD, Runge J, Newton A, Mison M, Xia L, Corbett C, Shin M, Sulyok LF, Durham A, Nie S, Singhal S, Holt D. Evaluation of Aminolevulinic Acid-Derived Tumor Fluorescence Yields Disparate Results in Murine and Spontaneous Large Animal Models of Lung Cancer. Sci Rep. 2019 05 21; 9(1):7629. PMID: 31113971.
    Citations: 2     Fields:    Translation:HumansAnimalsCells
  9. Predina JD, Keating J, Newton A, Corbett C, Xia L, Shin M, Frenzel Sulyok L, Deshpande C, Litzky L, Nie S, Kucharczuk JC, Singhal S. A clinical trial of intraoperative near-infrared imaging to assess tumor extent and identify residual disease during anterior mediastinal tumor resection. Cancer. 2019 03 01; 125(5):807-817. PMID: 30561757.
    Citations: 6     Fields:    Translation:HumansCTClinical Trials
  10. Predina JD, Newton AD, Corbett C, Shin M, Sulfyok LF, Okusanya OT, Delikatny EJ, Nie S, Gaughan C, Jarrar D, Pechet T, Kucharczuk JC, Singhal S. Near-infrared intraoperative imaging for minimally invasive pulmonary metastasectomy for sarcomas. J Thorac Cardiovasc Surg. 2019 05; 157(5):2061-2069. PMID: 31288365.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  11. Newton AD, Predina JD, Corbett CJ, Frenzel-Sulyok LG, Xia L, Petersson EJ, Tsourkas A, Nie S, Delikatny EJ, Singhal S. Optimization of Second Window Indocyanine Green for Intraoperative Near-Infrared Imaging of Thoracic Malignancy. J Am Coll Surg. 2019 02; 228(2):188-197. PMID: 30471345.
    Citations: 11     Fields:    Translation:HumansCTClinical Trials
  12. Newton AD, Predina JD, Nie S, Low PS, Singhal S. Intraoperative fluorescence imaging in thoracic surgery. J Surg Oncol. 2018 Aug; 118(2):344-355. PMID: 30098293.
    Citations: 14     Fields:    Translation:Humans
  13. Kennedy GT, Ukert BD, Predina JD, Newton AD, Kucharczuk JC, Polsky D, Singhal S. Implications of Hospital Volume on Costs Following Esophagectomy in the United States. J Gastrointest Surg. 2018 11; 22(11):1845-1851. PMID: 30066065.
    Citations: 3     Fields:    Translation:Humans
  14. Predina JD, Newton AD, Corbett C, Xia L, Shin M, Sulfyok LF, Okusanya OT, Cengel KA, Haas A, Litzky L, Kucharczuk JC, Singhal S. A Clinical Trial of TumorGlow to Identify Residual Disease During Pleurectomy and Decortication. Ann Thorac Surg. 2019 01; 107(1):224-232. PMID: 30028985.
    Citations: 3     Fields:    Translation:HumansCTClinical Trials
  15. Newton AD, Predina JD, Frenzel-Sulyok LG, Shin MH, Wang Y, Singhal S. Intraoperative near-infrared imaging can identify sub-centimeter colorectal cancer lung metastases during pulmonary metastasectomy. J Thorac Dis. 2018 Jul; 10(7):E544-E548. PMID: 30174930.
    Citations: 2     
  16. Predina JD, Newton A, Corbett C, Xia L, Sulyok LF, Shin M, Deshpande C, Litzky L, Barbosa E, Low PS, Kucharczuk JC, Singhal S. Localization of Pulmonary Ground-Glass Opacities with Folate Receptor-Targeted Intraoperative Molecular Imaging. J Thorac Oncol. 2018 07; 13(7):1028-1036. PMID: 29626619.
    Citations: 11     Fields:    Translation:Humans
  17. Predina JD, Newton AD, Keating J, Dunbar A, Connolly C, Baldassari M, Mizelle J, Xia L, Deshpande C, Kucharczuk J, Low PS, Singhal S. A Phase I Clinical Trial of Targeted Intraoperative Molecular Imaging for Pulmonary Adenocarcinomas. Ann Thorac Surg. 2018 03; 105(3):901-908. PMID: 29397932.
    Citations: 19     Fields:    Translation:HumansCTClinical Trials
  18. Predina JD, Newton AD, Xia L, Corbett C, Connolly C, Shin M, Sulyok LF, Litzky L, Deshpande C, Nie S, Kularatne SA, Low PS, Singhal S. An open label trial of folate receptor-targeted intraoperative molecular imaging to localize pulmonary squamous cell carcinomas. Oncotarget. 2018 Mar 02; 9(17):13517-13529. PMID: 29568374.
    Citations: 14     Fields:    
  19. Predina JD, Okusanya O, D Newton A, Low P, Singhal S. Standardization and Optimization of Intraoperative Molecular Imaging for Identifying Primary Pulmonary Adenocarcinomas. Mol Imaging Biol. 2018 02; 20(1):131-138. PMID: 28497233.
    Citations: 5     Fields:    Translation:Humans
  20. Predina JD, Newton A, Deshpande C, Low P, Singhal S. Utilization of targeted near-infrared molecular imaging to improve pulmonary metastasectomy of osteosarcomas. J Biomed Opt. 2018 01; 23(1):1-4. PMID: 29302953.
    Citations: 7     Fields:    Translation:Humans
  21. Predina JD, Newton A, Connolly C, Singhal S. Folate receptor-targeted molecular imaging improves identification of malignancy during pulmonary resection: a case report. J Cardiothorac Surg. 2017 Dec 04; 12(1):110. PMID: 29202877.
    Citations: 3     Fields:    Translation:Humans
  22. Singhal K, Newton AD, Corbett C, Predina JD. Management of partial anomalous pulmonary venous connections in patients requiring pulmonary resection: a case report and systematic review. J Thorac Dis. 2017 Dec; 9(12):5434-5439. PMID: 29312754.
  23. Predina JD, Fedor D, Newton AD, Xia L, Lee JYK, Guzzo T, Drebin J, Singhal S. Intraoperative Molecular Imaging: The Surgical Oncologist's North Star. Ann Surg. 2017 12; 266(6):e42-e44. PMID: 28837055.
    Citations: 4     Fields:    Translation:Humans
  24. Newton AD, Predina JD, Xia L, Roses RE, Karakousis GC, Dempsey DT, Williams NN, Kucharczuk JC, Singhal S. Surgical Management of Early-Stage Esophageal Adenocarcinoma Based on Lymph Node Metastasis Risk. Ann Surg Oncol. 2018 Jan; 25(1):318-325. PMID: 29147928.
    Citations: 15     Fields:    Translation:Humans
  25. Predina JD, Newton AD, Desphande C, Singhal S. Near-infrared intraoperative imaging during resection of an anterior mediastinal soft tissue sarcoma. Mol Clin Oncol. 2018 Jan; 8(1):86-88. PMID: 29387401.
    Citations: 4     
  26. Predina JD, Newton AD, Connolly C, Dunbar A, Baldassari M, Deshpande C, Cantu E, Stadanlick J, Kularatne SA, Low PS, Singhal S. Identification of a Folate Receptor-Targeted Near-Infrared Molecular Contrast Agent to Localize Pulmonary Adenocarcinomas. Mol Ther. 2018 02 07; 26(2):390-403. PMID: 29241970.
    Citations: 15     Fields:    Translation:HumansAnimals
  27. Predina JD, Newton AD, Keating J, Barbosa EM, Okusanya O, Xia L, Dunbar A, Connolly C, Baldassari MP, Mizelle J, Delikatny EJ, Kucharczuk JC, Deshpande C, Kularatne SA, Low P, Drebin J, Singhal S. Intraoperative Molecular Imaging Combined With Positron Emission Tomography Improves Surgical Management of Peripheral Malignant Pulmonary Nodules. Ann Surg. 2017 09; 266(3):479-488. PMID: 28746152.
    Citations: 23     Fields:    Translation:HumansCTClinical Trials
  28. Zeh R, Sheikh S, Xia L, Pierce J, Newton A, Predina J, Cho S, Nasrallah M, Singhal S, Dorsey J, Lee JYK. The second window ICG technique demonstrates a broad plateau period for near infrared fluorescence tumor contrast in glioblastoma. PLoS One. 2017; 12(7):e0182034. PMID: 28738091.
    Citations: 29     Fields:    Translation:HumansAnimalsCells
  29. Kennedy GT, Newton A, Predina J, Singhal S. Intraoperative near-infrared imaging of mesothelioma. Transl Lung Cancer Res. 2017 Jun; 6(3):279-284. PMID: 28713673.
    Citations: 8     
  30. Xia L, Zeh R, Mizelle J, Newton A, Predina J, Nie S, Singhal S, Guzzo TJ. Near-infrared Intraoperative Molecular Imaging Can Identify Metastatic Lymph Nodes in Prostate Cancer. Urology. 2017 Aug; 106:133-138. PMID: 28438626.
    Citations: 6     Fields:    Translation:HumansAnimalsCells
  31. McMillan MT, Ojerholm E, Verma V, Higgins KA, Singhal S, Predina JD, Berman AT, Grover S, Robinson CG, Simone CB. Radiation Treatment Time and Overall Survival in Locally Advanced Non-small Cell Lung Cancer. Int J Radiat Oncol Biol Phys. 2017 08 01; 98(5):1142-1152. PMID: 28721898.
    Citations: 32     Fields:    Translation:Humans
  32. Venegas O, Newton A, Vergara N, Singhal S, Predina JD. Tracheal Glomus Tumor: A Case Report and Review of the Literature. Rare Tumors. 2017 Mar 24; 9(1):6848. PMID: 28458792.
    Citations: 5     
  33. Predina JD, Newton A, Kennedy G, Lee MK, Singhal S. Near-Infrared Intraoperative Imaging Can Successfully Identify Malignant Pleural Mesothelioma After Neoadjuvant Chemotherapy. Mol Imaging. 2017 Jan-Dec; 16:1536012117723785. PMID: 28856921.
    Citations: 4     Fields:    Translation:Humans
  34. Keating J, Newton A, Venegas O, Nims S, Zeh R, Predina J, Deshpande C, Kucharczuk J, Nie S, Delikatny EJ, Singhal S. Near-Infrared Intraoperative Molecular Imaging Can Locate Metastases to the Lung. Ann Thorac Surg. 2017 Feb; 103(2):390-398. PMID: 27793401.
    Citations: 25     Fields:    Translation:HumansAnimals
  35. Newton AD, Kennedy GT, Predina JD, Low PS, Singhal S. Intraoperative molecular imaging to identify lung adenocarcinomas. J Thorac Dis. 2016 Oct; 8(Suppl 9):S697-S704. PMID: 28066672.
    Citations: 6     
  36. Xia L, Venegas OG, Predina JD, Singhal S, Guzzo TJ. Intraoperative Molecular Imaging for Post-Chemotherapy Robot-Assisted Laparoscopic Resection of Seminoma Metastasis: A Case Report. Clin Genitourin Cancer. 2017 02; 15(1):e61-e64. PMID: 27793611.
    Citations: 2     Fields:    Translation:Humans
  37. Predina JD, Keating J, Venegas O, Nims S, Singhal S. Neoadjuvant intratumoral immuno-gene therapy for non-small cell lung cancer. Discov Med. 2016 04; 21(116):275-81. PMID: 27232513.
    Citations:    Fields:    Translation:HumansAnimalsCells
  38. Predina JD, Keating J, Patel N, Nims S, Singhal S. Clinical implications of positive margins following non-small cell lung cancer surgery. J Surg Oncol. 2016 Mar; 113(3):264-9. PMID: 26719121.
    Citations: 7     Fields:    Translation:Humans
  39. De Jesus E, Keating JJ, Kularatne SA, Jiang J, Judy R, Predina J, Nie S, Low P, Singhal S. Comparison of Folate Receptor Targeted Optical Contrast Agents for Intraoperative Molecular Imaging. Int J Mol Imaging. 2015; 2015:469047. PMID: 26491562.
    Citations: 23     
  40. Predina JD, Morse CR. Minimally invasive esophagectomy and its current role in esophageal cancer. Minerva Chir. 2014 Dec; 69(6):363-370. PMID: 25300696.
    Citations: 1     Fields:    
  41. Quatromoni JG, Predina JD, Bhojnagarwala P, Judy RP, Jiang J, De Jesus EM, Kapoor V, Cheng G, Okusanya OT, Eruslanov E, Singhal S. Adenoviral-based immunotherapy provides local disease control in an orthotopic murine model of esophageal cancer. J Immunother. 2014 Jun; 37(5):283-92. PMID: 24810640.
    Citations: 5     Fields:    Translation:HumansAnimalsCells
  42. Liu Y, Wang L, Predina J, Han R, Beier UH, Wang LC, Kapoor V, Bhatti TR, Akimova T, Singhal S, Brindle PK, Cole PA, Albelda SM, Hancock WW. Inhibition of p300 impairs Foxp3? T regulatory cell function and promotes antitumor immunity. Nat Med. 2013 Sep; 19(9):1173-7. PMID: 23955711.
    Citations: 87     Fields:    Translation:HumansAnimalsCells
  43. Quatromoni JG, Suzuki E, Okusanya O, Judy BF, Bhojnagarwala P, Venegas O, Eruslanov E, Predina JD, Albelda SM, Singhal S. The timing of TGF-ß inhibition affects the generation of antigen-specific CD8+ T cells. BMC Immunol. 2013 Jul 17; 14:30. PMID: 23865808.
    Citations: 6     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  44. Yu Z, Predina JD, Cheng G. Refractoriness of interferon-beta signaling through NOD1 pathway in mouse respiratory epithelial cells using the anticancer xanthone compound. World J Biol Chem. 2013 May 26; 4(2):18-29. PMID: 23710296.
  45. Yang RL, Hashimoto DA, Predina JD, Bowens NM, Sonnenberg EM, Cleveland EC, Lawson C, Morris JB, Kelz RR. The virtual-patient pilot: testing a new tool for undergraduate surgical education and assessment. J Surg Educ. 2013 May-Jun; 70(3):394-401. PMID: 23618451.
    Citations: 2     Fields:    Translation:Humans
  46. Predina J, Eruslanov E, Judy B, Kapoor V, Cheng G, Wang LC, Sun J, Moon EK, Fridlender ZG, Albelda S, Singhal S. Changes in the local tumor microenvironment in recurrent cancers may explain the failure of vaccines after surgery. Proc Natl Acad Sci U S A. 2013 Jan 29; 110(5):E415-24. PMID: 23271806.
    Citations: 59     Fields:    Translation:HumansAnimalsCellsPHPublic Health
  47. Predina JD, Kapoor V, Judy BF, Cheng G, Fridlender ZG, Albelda SM, Singhal S. Cytoreduction surgery reduces systemic myeloid suppressor cell populations and restores intratumoral immunotherapy effectiveness. J Hematol Oncol. 2012 Jun 28; 5:34. PMID: 22742411.
    Citations: 18     Fields:    Translation:AnimalsCells
  48. Predina JD, Judy B, Fridlender ZG, Aliperti LA, Madajewski B, Kapoor V, Cheng G, Quatromoni J, Okusanya O, Singhal S. A positive-margin resection model recreates the postsurgical tumor microenvironment and is a reliable model for adjuvant therapy evaluation. Cancer Biol Ther. 2012 Jul; 13(9):745-55. PMID: 22617772.
    Citations: 16     Fields:    Translation:HumansAnimalsCells
  49. Predina JD, Judy B, Kapoor V, Blouin A, Aliperti LA, Levine D, Okusanya OT, Quatromoni J, Fridlender ZG, Singhal S. Characterization of surgical models of postoperative tumor recurrence for preclinical adjuvant therapy assessment. Am J Transl Res. 2012; 4(2):206-18. PMID: 22611473.
    Citations: 4     
  50. Judy BF, Aliperti LA, Predina JD, Levine D, Kapoor V, Thorpe PE, Albelda SM, Singhal S. Vascular endothelial-targeted therapy combined with cytotoxic chemotherapy induces inflammatory intratumoral infiltrates and inhibits tumor relapses after surgery. Neoplasia. 2012 Apr; 14(4):352-9. PMID: 22577350.
    Citations: 16     Fields:    Translation:Animals
  51. Predina JD, Anolik RB, Judy B, Akers S, Freiman D, Ahmad N, Singhal S. Intramural esophageal dissection in a young man with eosinophilic esophagitis. Ann Thorac Cardiovasc Surg. 2012; 18(1):31-5. PMID: 21959190.
    Citations: 6     Fields:    Translation:Humans
  52. Predina JD, Judy B, Aliperti LA, Fridlender ZG, Blouin A, Kapoor V, Laguna B, Nakagawa H, Rustgi AK, Aguilar L, Aguilar-Cordova E, Albelda SM, Singhal S. Neoadjuvant in situ gene-mediated cytotoxic immunotherapy improves postoperative outcomes in novel syngeneic esophageal carcinoma models. Cancer Gene Ther. 2011 Dec; 18(12):871-83. PMID: 21869822.
    Citations: 19     Fields:    Translation:HumansAnimalsCells
  53. Moon EK, Carpenito C, Sun J, Wang LC, Kapoor V, Predina J, Powell DJ, Riley JL, June CH, Albelda SM. Expression of a functional CCR2 receptor enhances tumor localization and tumor eradication by retargeted human T cells expressing a mesothelin-specific chimeric antibody receptor. Clin Cancer Res. 2011 Jul 15; 17(14):4719-30. PMID: 21610146.
    Citations: 216     Fields:    Translation:HumansAnimalsCells
  54. Predina JD, Puc MM, Bergey MR, Sonnad SS, Kucharczuk JC, Staddon A, Kaiser LR, Shrager JB. Improved survival after pulmonary metastasectomy for soft tissue sarcoma. J Thorac Oncol. 2011 May; 6(5):913-9. PMID: 21750417.
    Citations: 26     Fields:    Translation:Humans
  55. Aliperti LA, Predina JD, Vachani A, Singhal S. Local and systemic recurrence is the Achilles heel of cancer surgery. Ann Surg Oncol. 2011 Mar; 18(3):603-7. PMID: 21161729.
    Citations: 38     Fields:    Translation:Humans
  56. Predina JD, Kunkala M, Aliperti LA, Singhal AK, Singhal S. Sleeve lobectomy: current indications and future directions. Ann Thorac Cardiovasc Surg. 2010 Oct; 16(5):310-8. PMID: 21030916.
    Citations: 16     Fields:    Translation:Humans
  57. Predina JD, Kotloff RM, Miller WT, Singhal S. Recurrent spontaneous pneumothorax in a patient with Birt-Hogg-Dubé syndrome. Eur J Cardiothorac Surg. 2011 Mar; 39(3):404-6. PMID: 20692178.
    Citations: 1     Fields:    Translation:Humans
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Funded by the NIH National Center for Advancing Translational Sciences through its Clinical and Translational Science Awards Program, grant number UL1TR002541.